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34results about How to "Rapid and easy identification" patented technology

Therapeutic compositions and methods

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and structurally and functionally related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions.
Owner:THE RGT OF THE UNIV OF MICHIGAN

Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties

The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides novel 1,4-benzodiazepine-2,5-dione compounds, and methods of using novel 1,4-benzodiazepine-2,5-dione compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.
Owner:RGT UNIV OF MICHIGAN

Methods and kits for detecting cerebrospinal fluid in a sample

The present invention relates to detection of the presence or absence of cerebrospinal fluid (CSF) in a sample, in particular to the analysis of the CSF protein lipocalin-type prostaglandin D2 synthase (PGDS). The present invention provides assays for the analysis of PGDS indicating the presence or absence of CSF in a sample.
Owner:PENTYALA SRINIVAS N

Ras association domain containing protein

The invention provides a mammalian cDNA which encodes a mammalian Ras association domain containing protein. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of cell proliferative and inflammatory disorders, particularly thymus hyperplasia, allergies, asthma, and hypereosinophilia. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
Owner:INCYTE

Homeodomain fusion proteins and uses thereof

Provided herein are fusion proteins comprising a homeodomain fusion protein domain and a transcription modulator domain for treatment of various diseases or disorders such as cancer. The homeodomain fusion protein domain binds to a target gene and the transcription modulator domain either activates or represses gene transcription. The present invention also relates to polynucleotides encoding the fusion proteins, vectors comprising the polynucleotides, cells comprising the polynucleotides, vectors, or fusion proteins. Also provided are methods of use and compositions for delivery of the fusion proteins.
Owner:PRESIDENT & FELLOWS OF HARVARD COLLEGE +1

Nucleic acids encoding 3-ketoacyl-ACP reductase from Moraxella catarrahalis

InactiveUS6632636B1Extended half-lifeIncrease intracellular stabilitySugar derivativesBacteriaPDAT enzymeOpen reading frame
The present invention provides the genomic sequences of a library of purified nucleic acid molecules, or their complements, comprising the genome of <HIL><PDAT>Moraxella catarrhalis< / ITALIC><PDAT>. The invention also provides the identification of open reading frames contained within the nucleic acid molecules of the library. The present invention further provides for the use of the nucleic acid molecules, their complements or fragments, and proteins or portions thereof for identifying ligands and useful diagnostic and therapeutic compositions. In addition the invention provides for vectors, host cells and methods for producing <HIL><PDAT>M. catarrhalis < / ITALIC><PDAT>proteins or portions thereof.< / PTEXT>
Owner:MERCK & CO INC

Apparatus and method for cell analysis

A cell analysis apparatus includes a test sample preparation part for preparing a test sample by treating an analyte with a dye for staining an intracellular substance of cells in the analyte, a detector for detecting scattered light and fluorescence from each cell in the test sample, and a controller for identifying living mononuclear cells based on the scattered light and the fluorescence detected by the detector. A cell analysis method includes preparing a test sample by treating the analyte with a dye for staining an intracellular substance of cells in the analyte; detecting scattered light and fluorescence from each cell in the test sample; and identifying living mononuclear cells based on the scattered light and the fluorescence detected.
Owner:SYSMEX CORP

Methods and systems for automatically rendering information on a display of a building information system

ActiveUS20070257937A1Easy identification of graphicalIncrease contrastImage enhancement2D-image generationGraphicsDisplay device
A method, system and computer program product for automatically rendering information on a display screen of a building information system. Following generation of a plan image, such as a floor or site plan image, the plan image is modified and subsequently rendered on the display screen. The plan image is modified by adjusting the contrast ratio of the plan image such that, when graphical elements, such as icons representing elevators, evacuation stairways and fire hydrants, are rendered on the display screen overlaying the modified plan image, the graphical elements are visually distinct from the modified plan image.
Owner:HONEYWELL INT INC

Pigmented decontaminating gel and method for decontaminating surfaces using said gel

A decontamination gel is provided consisting of a colloidal solution comprising 0.1% to 30% by mass, preferably 0.1% to 25% by mass, still more preferably from 5% to 25% by mass, even more preferably 8% to 20% by mass, based on the mass of the gel, of at least one inorganic viscosifying agent; 0.1 to 10 mol / L of gel, preferably 0.5 to 10 mol / L of gel, still more preferably 1 to 10 mol / L of gel of at least one active decontamination agent; 0.01% to 10% by mass, preferably 0.1% to 5% by mass based on the mass of the gel of at least one mineral pigment; optionally, 0.1% to 2% by mass based on the mass of the gel, of at least one surfactant; optionally, 0.05% to 5% by mass, preferably 0.05% to 2% by mass, based on the mass of the gel, of at least one super-absorbent polymer; and the balance of solvent.
Owner:COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

Compositions and methods related to graft-versus-host disease

The present invention relates to compositions and methods for the treatment and management of graft-versus-host disease and other diseases. In some embodiments, the present invention provides therapies comprising treating subjects with agents that inhibit TNF-alpha and IL-1.
Owner:RGT UNIV OF MICHIGAN

Insect g protein-coupled receptor genes and uses thereof

InactiveUS20040248791A1Rapid and easy identificationSuppresses growthBacteriaPeptide/protein ingredientsG Protein-Coupled Receptor GeneAntiparasite agent
The present invention provides isolated nucleic acids encoding insect G protein-coupled receptor (GPCR) polypeptides, isolated insect GPCR polypeptides, and uses thereof. Further provided are recombinant proteins and methods for identifying inhibitors to these proteins. The disclosed insect GPCR nucleic acids and polypeptides can be used in screening assays to identify modulating compounds. Protein inhibitors active in the methods disclosed herein are useful as insecticidal, ectoparasiticidal, antiparasitic, anthenenthic and acaracidal agents.
Owner:SYNGENTA PARTICIPATIONS AG

Method and apparatus for identifying vulnerability information using keyword analysis for banner of open port

Provided are a method and an apparatus for identifying computer system information which process banner information of an open port of a computer system, create a CPE tree by analyzing a CPE dictionary, and search keywords of respective levels of the CPE tree in a banner and generate one or more CPEs based on the CPE tree observing a format of the CPE dictionary to select CPEs which most match information of an operating system or an application program of a specific computer system among various CPE candidates and rapidly and easily identify CPE type vulnerability information which can interlock with CVE vulnerability information.
Owner:KOREA INTERNET & SECURITY AGENCY

Promoter Variants Of The Alpha-7 Nicotinic Acetylcholine Receptor

InactiveUS20100047795A1Rapid and easy identificationAvoid immuno-deactivationSugar derivativesPeptide/protein ingredientsAcetylcholine nicotinic receptorAllele
The present invention is directed to methods and compositions related to α7 acetylcholine nicotinic receptor genes, in particular, the human α7 nicotinic acetylcholine receptor gene. The human α7 nicotinic acetylcholine receptor gene is associated with the pathophysiological aspects of the disease schizophrenia. The present invention further provides methods and compositions to screen populations for abnormal α7 alleles, as well as methods and compositions for development of therapeutics.
Owner:UNITED STATES OF AMERICA

Porphorymonas gingivalis polypeptides and nucleotides

The present invention relates to isolated Porphorymonas gingivalis polypeptides and nucleotides. The polypeptides include; an amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532; or an amino acid sequence at least 85%, preferably at least 95%, identical to an amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532; or at least 40 amino acids having a contiguous sequence of at least 40 amino acids identical to a contiguous amino acid sequence selected from the group consisting of SEQ. ID. NO. 265 to SEQ. ID. NO. 528, SEQ. ID. NO. 531 and SEQ. ID. NO. 532.
Owner:CSL LTD +1

Aquaporin-8 variant

The invention provides a mammalian cDNA which encodes a mammalian AQP8V. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of pancreatic disorders, particularly type I diabetes. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
Owner:INCYTE

System, method, and apparatus for passive, multi-spectral, optical identification of remote objects

A system passively identifies objects at large distances with an integrated two-dimensional pattern, spectral tailoring, and an imaging system. Encoded information allows objects of various origin and configuration to be easily and rapidly identified by optical means, but is invisible to the naked eye. The devices used for detecting the objects may be ground-based, airborne, or even satellite-based, and can track engagements of such marked objects in real-time. A tailored reflective surface at a specific wavelength band is applied to the exteriors of the objects to form a unique signature. A scanning system passively records the light emanating from the signature in the specific band, and recognizes the signature to discern what the object is based on a database of information.
Owner:LOCKHEED MARTIN CORP

Method of detecting cardiac hypertrophy through probe hybridization and gene expression analysis

The present invention is based upon the identification of genes which are differentially expressed in hypertrophic cardiac tissue as compared to normal cardiac tissue. Accordingly, the present invention provides nucleotide sequences of genes selected from the group consisting of CH-1, CH-2, CH-3, CH-4, CH-5, CH-6, CH-7, CH-8, and CH-9 and amino acid sequences of their encoded proteins, as well as derivatives (e.g., fragments) and analogs thereof. The invention also provides therapeutic methods and pharmaceutical compositions which are based on the promotion or inhibition of the function of the differentially expressed genes. The invention further provides methods of diagnosis, prognosis and screening for a disposition for diseases or disorders associated with cardiac hypertrophy. Methods for screening for modulators of the protein products of the differentially expressed genes in cardiac hypertrophy tissue are additionally provided.
Owner:SHIMKETS RICHARD A +1

Promoter variants of the alpha-7 nicotinic acetylcholine receptor

InactiveUS7572580B2Avoid immuno-deactivationAvoid immune responseFungiBacteriaDiseaseAcetylcholine nicotinic receptor
The present invention is directed to methods and compositions related to α7 acetylcholine nicotinic receptor genes, in particular, the human α7 nicotinic acetylcholine receptor gene. The human α7 nicotinic acetylcholine receptor gene is associated with the pathophysiological aspects of the disease schizophrenia. The present invention further provides methods and compositions to screen populations for abnormal α7 alleles, as well as methods and compositions for development of therapeutics.
Owner:THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPT OF VETERANS AFFAIRS

Nucleic acid sequences from Drosophila melanogaster that encode proteins essential for viability and uses thereof

Nucleotide sequences are isolated from Drosophila melanogaster that code for proteins essential for viability. These proteins are useful for discovering new insecticides based on the essentiality of the nucleotide sequences for Drosophila viability. Further provided are recombinant proteins and methods for identifying inhibitors to these proteins. Protein inhibitors active in the methods disclosed herein are useful as insecticidal, ectoparasiticidal, antiparasitic, anthementhic and acaracidal agents.
Owner:SYNGENTA PARTICIPATIONS AG

Growth-related inflammatory and immune response protein

InactiveUS20030166300A1Facilitate interactionIncreased frequencyFungiBacteriaImmunoreactive proteinAntibody
The invention provides a mammalian cDNA which encodes a mammalian GRIIP. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of disorders associated with inflammation and immune response, particularly cancers of the immune system. The invention additionally provides expression vectors and host cells for the production of the protein and a transgenic model system.
Owner:INCYTE

Method and apparatus for identifying vulnerability information using keyword analysis for banner of open port

Provided are a method and an apparatus for identifying computer system information which process banner information of an open port of a computer system, create a CPE tree by analyzing a CPE dictionary, and search keywords of respective levels of the CPE tree in a banner and generate one or more CPEs based on the CPE tree observing a format of the CPE dictionary to select CPEs which most match information of an operating system or an application program of a specific computer system among various CPE candidates and rapidly and easily identify CPE type vulnerability information which can interlock with CVE vulnerability information.
Owner:KOREA INTERNET & SECURITY AGENCY
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