2 results about "Benzodiazepine Compounds" patented technology

Provided are a new type of benzodiazepine compound, a preparation method thereof, and a use thereof. The short-acting benzodiazepine derivative has the characteristics of rapid onset, short action time, strong depth, fast metabolism, and fast awakening. In the anesthesia experiments on mice and rats, the short-acting benzodiazepine derivative has an onset time comparable to that of remazepam, but the action time and awakening time are significantly shortened, and the action depth of some compounds is significantly enhanced, and has the characteristics of faster onset, shorter action time, greater action strength, faster metabolism, and faster awakening. In the long-term infusion anesthesia experiment on rats, compared with remazepam, the short-acting benzodiazepine derivative has significantly shortened awakening time and recovery time, and has the characteristics of faster awakening and faster recovery.

The present disclosure relates to benzodiazepine compounds and pharmaceutically acceptable salts thereof, their uses in medicine, pharmaceutical compositions containing them, processes for their preparation, and intermediates used in such processes. The benzodiazepine compounds can be useful in the treatment, prevention, inhibition, and amelioration of RSV infection.