Angina pectoris is a clinical syndrome mainly manifesting paroxysmal chest pain or cheat discomfort caused by coronary artery insufficiency, myocardium sharp temporary ischemia or anoxia. Angina pectoris is characterized by prothorax paroxysmal and crushing pain, can be companied by other symptoms, namely, pain mainly positioned at the rear part of breastbone, can radiate to precardium and left upper extremity, and often happens during labor and rage. The drug is prepared by combining lycopus herb, Chinese trumpetcreeper, prepared rehmannia root, peach kernel, zedoary, rhizome of Sichuan lovage, radix paeoniae alba, red flower, burred tuber, frankincense, flatstem astragalus seed, achyranthes root, red sage root, bark of Chinese redbud, Chinese caterpillar fungus, faeces trogopterpri, giant knotweed, jasminum amplexicaule Buch, Chinese date, pangolin, leonurus heterophyllus, common myrrh tree, black sesame, dalbergia wood, caulis spatholobi, corydalis tuber, angelica sinensis, curcuma root, sappan caesalpinia, curcuma, atractylodes macrocephala, seed of cow-fat and herb of diverse wormwood, and the drugs are combined to ensure that efficacies of all the drugs generate a synergistic action, so that angina pectoris can be effectively treated.