Chinese patent medicine for treating vascular dementia and preparation method thereof

A technology of vascular dementia and Chinese patent medicine, which is applied in the field of traditional Chinese medicine, can solve the problems of difficulty in obtaining satisfactory prevention and treatment effects, long-term curative effect to be evaluated, and restrictions on clinical application, and achieve good controllability and stability, low price, Clinically significant effect

Inactive Publication Date: 2014-04-16
NANYANG INST OF TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the pathway of action of some drugs is not yet clear, the side effects are obvious, the long-term efficacy needs to be evaluated, and the price is expensive, they are often limited to the control of basic diseases, etc., and they do not work on every link in the pathogenesis of VD, so it is difficult to obtain Satisfactory control effect, so it seriously restricts its clinical application

Method used

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  • Chinese patent medicine for treating vascular dementia and preparation method thereof
  • Chinese patent medicine for treating vascular dementia and preparation method thereof
  • Chinese patent medicine for treating vascular dementia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A Chinese patent medicine for treating vascular dementia, which is made from the following raw Chinese medicines in parts by weight:

[0022] Rehmannia glutinosa 18g, cornus 12g, astragalus 9g, salvia miltiorrhiza 15g, safflower 12g, Chuanxiong 12g, Zhuru 6g, Shichangpu 9g, licorice 6g. The cornus, calamus and bamboo rut in the above formula are processed in the following ways: steaming cornus with wine; frying shichangpu with bran; and making zhuru with ginger.

[0023] Above-mentioned raw material Chinese medicine is prepared according to the following steps:

[0024] 1. Take the two herbs of Shichangpu and Chuanxiong, and use supercritical CO 2 Method Extract the volatile oil, take the powder of the two herbs according to the above dosage, put it into the extraction kettle, the pressure of the separation kettle is 5.5-6.0MPa, the pressure of the extraction kettle is 15MPa, the temperature of the extraction kettle is 30°C, the temperature of the separation kettle is ...

Embodiment 2

[0030] A kind of Chinese patent medicine for treating vascular dementia, made of the following raw materials by weight: rehmannia glutinosa 20g, cornus 15g, astragalus 10g, salvia miltiorrhiza 12g, safflower 15g, chuanxiong 15g, Zhuru 9g, Shichangpu 10g, licorice 9g. The cornus, calamus and bamboo rut in the above formula are processed in the following ways: steaming cornus with wine; frying shichangpu with bran; and making zhuru with ginger.

[0031] Preparation method: with embodiment 1.

Embodiment 3

[0033] A kind of Chinese patent medicine for treating vascular dementia, made from the following raw materials by weight: rehmannia glutinosa 15g, cornus 10g, astragalus 8g, salvia miltiorrhiza 10g, safflower 9g, chuanxiong 12g, zhuru 6g, calamus 9g, licorice 5g. The cornus, calamus and bamboo rut in the above formula are processed in the following ways: steaming cornus with wine; frying shichangpu with bran; and making zhuru with ginger.

[0034] Preparation method: with embodiment 1.

[0035] Main function of medicine of the present invention and treatment disease:

[0036] 1. Main functions: Tonify qi and invigorate the kidney, remove blood stasis and resolve phlegm, refresh the brain and resuscitate.

[0037] 2. Treatment of diseases: vascular dementia, TCM syndrome differentiation is kidney deficiency and phlegm stasis type.

[0038] 3. Usage and dosage: Adults take 10g three times a day after meals.

[0039] The clinical observation of medicine of the present inv...

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Abstract

The invention discloses a Chinese patent medicine for treating vascular dementia and a preparation method thereof. The Chinese patent is prepared from the following raw materials in parts by weight: 15-20 parts of prepared rehmannia, 10-15 parts of cornus pulp, 8-12 parts of astragalus membranaceus, 12-18 parts of salviae miltiorrhizae, 9-15 parts of safflower, 9-15 parts of ligusticum wallichii, 6-12 parts of bamboo shavings, 6-12 parts of rhizoma acori graminei, and 4-10 parts of liquorice. The Chinese patent medicine has the effects of invigorating qi and tonifying kidney, removing blood stasis and reducing phlegm, and restoring consciousness and inducing resuscitation, can be used for improving the clinical syndrome of a patient with vascular dementia, has an improving effect to traditional Chinese medicine score, cognitive competence, daily living activity and brain neurotransmitter of the patient with vascular dementia, has a total effective rate of 85.4 percent, is reliable in effect for treating vascular dementia, does not have remarkable toxic or side effect, and is high in bioavailability and good in controllability and stability.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a Chinese patent medicine for treating vascular dementia and a preparation method thereof. Background technique [0002] Vascular dementia (Vascular Dementia, VD) is a dementia syndrome caused by brain tissue damage caused by a series of cerebrovascular lesions. It is the result of degeneration caused by stroke damage after the intelligence is fully developed. One of the main types of dementia. A mental disorder characterized by forgetfulness, disorientation, misunderstanding, and poor calculation ability, among which memory loss is the early core symptom [1]. Epidemiological surveys have shown that the incidence of VD increases sharply with age, and the high prevalence and incidence of dementia have brought serious burdens to families and society. With the development of social aging and the increase of stroke patients, VD has become the main type of demen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61P25/28A61P9/10
Inventor 胡久略卞华史马广寒张延英张瓅方马长德路鹏
Owner NANYANG INST OF TECH
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