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Composition for treating diabetic gastroparesis and application thereof

A composition and technology of gastroparesis, applied in the direction of drug combination, organic active ingredients, medical preparations containing active ingredients, etc., can solve the problem of increased drug dosage, and achieve the effect of short treatment period, good effect and complete dispensing

Active Publication Date: 2021-08-27
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are various treatment methods for this disease, and the treatment methods of Western medicine are simple, such as metoclopramide, domperidone, mosapride, itopride, cisapride, quick effect, but repeated symptoms, drugs The dosage is gradually increasing; traditional Chinese medicine treatment is mainly based on warming, nourishing and tonifying. There are also related reports on acupuncture and moxibustion. For example, Zhi Mujun et al. Conception of Chinese Acupuncture and Moxibustion

Method used

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  • Composition for treating diabetic gastroparesis and application thereof
  • Composition for treating diabetic gastroparesis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] 200 parts by weight of Citrus aurantium, 20 parts by weight of Atractylodes macrocephala, 100 parts by weight of ginseng

[0052] 30 parts by weight of medlar, 150 parts by weight of donkey-hide gelatin, 20 parts by weight of Polygonum multiflorum

[0053] 500 parts by weight of Semen Cassiae and 30 parts by weight of Aloe Vera.

[0054] Grind donkey-hide gelatin into fine powder (through 80-mesh sieve) for later use; ginseng, Polygonum multiflorum, Semen Cassiae, and aloe were refluxed and extracted with 40% ethanol for 3 times, each time for 1 hour, the extract was filtered, ethanol was recovered, and concentrated into an extract for later use; Lycium barbarum, Add 5 times of water to Atractylodes macrocephala and Citrus aurantium, soak for 3 hours, decoct for 3 hours, add 5 times of water, decoct for 2 hours, combine the decoction liquid, filter, concentrate under reduced pressure until the medicinal materials: water = 1:1, adjust alcohol to 85%, cooled for 12 hours...

Embodiment 2

[0056] 50 parts by weight of Citrus aurantium, 100 parts by weight of Atractylodes macrocephala, 20 parts by weight of ginseng

[0057] 150 parts by weight of medlar, 30 parts by weight of donkey-hide gelatin, 400 parts by weight of Polygonum multiflorum

[0058] 30 parts by weight of Semen Cassiae and 600 parts by weight of Aloe Vera.

[0059] Donkey-hide gelatin melted into donkey-hide gelatin solution for later use; ginseng, Polygonum multiflorum, Cassia seed, and aloe plus 80% ethanol for reflux extraction once, each time for 3 hours, the extract was filtered, ethanol was recovered, and concentrated into an extract for later use; Lycium barbarum, Atractylodes macrocephala, Citrus aurantium Add 10 times of water, soak for 0.5 hours, decoct for 1 hour, add 10 times of water, decoct for 1 hour, combine the decoction liquid, filter, concentrate under reduced pressure until medicinal materials: water = 3:1, adjust alcohol to 65%, Cooling for 48 hours, filtering, and concentrat...

Embodiment 3

[0061] 150 parts by weight of Citrus aurantium, 20 parts by weight of Atractylodes macrocephala, 20 parts by weight of ginseng

[0062] 100 parts by weight of medlar, 30 parts by weight of donkey-hide gelatin, 150 parts by weight of Polygonum multiflorum

[0063] 80 parts by weight of cassia seed and 200 parts by weight of aloe.

[0064] Grind donkey-hide gelatin into fine powder (through 80 mesh sieve) for later use; ginseng, Polygonum multiflorum, Semen Cassiae, and aloe were refluxed and extracted twice with 65% ethanol, each time for 2 hours, the extract was filtered, ethanol was recovered, and concentrated into an extract for later use; Lycium barbarum, Add 8 times of water to Atractylodes macrocephala and Citrus aurantium, soak for 1 hour, decoct for 2 hours, add 5 times of water, decoct for 1 hour, combine the decoction liquid, filter, concentrate under reduced pressure until medicinal materials: water = 3:1, adjust alcohol to 40%, cooled for 48 hours, filtered, and co...

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Abstract

The invention belongs to the field of traditional Chinese medicine application, and particularly discloses a composition for treating diabetic gastroparesis and an application thereof. The composition contains ginseng, bighead atractylodes rhizome, colla corii asini, polygonum multiflorum, fructus lycii, semen cassiae, aloe and fructus aurantii immaturus. The traditional Chinese medicine adopts pure traditional Chinese medicine raw materials, is complete in monarch, minister, assistant and guide, and is suitable for cases. The clinical medication feedback shows that the composition can effectively treat gastroparesis syndrome, especially diabetic gastroparesis, and is short in treatment course and good in effect; and animal experiments show that the effective rate of the medicine for treatment is 95% or above. The traditional Chinese medicine composition can be added into health-care products and food according to a certain proportion to prepare products with the same curative effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating diabetic gastroparesis and an application thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] In recent years, with the change of people's lifestyle, diabetes mellitus (DM) has become the third largest non-communicable disease in the world, and the incidence rate is increasing year by year. From the perspective of pathogenesis, diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia, which is caused by defects in insulin secretion or impaired biological functions, or both. During the onset of diabetes, long-term hyperglycemia can lead to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. [0003] From a genetic point of view, there is obvious genetic heterogeneity in both diabetes type 1 and type 2 diabetes, and there is a phenomenon of fam...

Claims

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Application Information

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IPC IPC(8): A61K31/216A61P35/04
CPCA61K31/216A61P35/04
Inventor 张贵民黄志艳陆杰
Owner LUNAN PHARMA GROUP CORPORATION
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