Application of composition in preparation of medicine for treating diabetic gastroparesis
A composition and drug technology, applied in the field of medicine, can solve the undisclosed problems such as the application of Huanghou Zhixie dripping pills
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[0029] Example 1 Huanghou Zhixie Dropping Pills Treating Drug Effects of Diabetic Gastroparesis (DGP) Rats
[0030] (1) Construction of DGP rat model
[0031] 100 5-6 week-old clean healthy male SD rats (provided by Shanghai Jihui Experimental Animal Breeding Co., Ltd., license number SCXK (Shanghai) 2017-0012), were raised in Suzhou Xishan Zhongke Pharmaceutical Research and Development Co., Ltd., After 1 week of adaptive feeding, 10 rats were randomly selected as blank control rats, and the rest were model rats; after all rats were fasted for 12 hours, 10 blank control rats were intraperitoneally injected with 0.1mol / L citric acid buffer ( pH=4.5), the model rats were injected intraperitoneally with 1% streptozotocin (STZ, dissolved in the above-mentioned citric acid buffer), and the dosage was 60mg / kg; the tail vein blood sampling of the model rats after 72h measured the blood glucose value, and screening Rats with blood glucose ≥ 16.7mmol / L. Qualified rats use high-fat a...
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