The invention belongs to the technical field of road marks and aims at providing a night continuously self-luminous and highly-reflective road mark. The production method of the night continuously self-luminous and highly-reflective road mark comprises combining cementing materials, curing agent, filler, paint, reflective materials, luminous materials and glass beads at a certain ratio, and then spreading the materials layer by layer on a road surface. The night continuously self-luminous and highly-reflective road mark can achieve continuous self-illumination, and with the highly-reflective materials, provide better reflective effects, thereby meeting the original standard requirements on properties such as non-sticking drying time, pressure resistance, wear resistance and chromaticity, and meanwhile, achieving higher reflective performance and better energy storage effects compared with traditional marks; the night continuously self-luminous and highly-reflective road mark can achieve continuous self-illumination, so that, during night driving and within the light range of car lamps, the night continuously self-luminous and highly-reflective road mark is higher in reflective performance, clearer in marking, wider in view field and capable of ensuring driving safety; besides, through self-illumination in the range where car light cannot reach, the night continuously self-luminous and highly-reflective road mark can indicate the heading direction for drivers to reduce accidents.