The invention relates to a 
drug sustained-release 
microsphere capable of being embedded in 
intraocular lens loop and a preparation method of the 
drug sustained-release 
microsphere. The 
drug sustained-release 
microsphere prepared by the provided method can be used for effectively preventing and treating 
microorganism infection and antagonistic inflammatory reaction after a 
cataract surgery, reducing the occurrence rate of intraocular 
inflammation infection after the 
cataract surgery, and preventing and inhibiting after-cataract, so as to improve visual quality after the 
surgery. The technical scheme is that according to the drug sustained-release microsphere capable of being embedded in the 
intraocular lens loop, the drug sustained-release microsphere is formed by mixing drugs and a carrier at the ratio of 1 to (10000-1), and the drug sustained-release microsphere is 100-800mm in 
diameter. The preparation method of the drug sustained-release microsphere capable of being embedded in the 
intraocular lens loop sequentially comprises the following steps: (1) mixing the drugs and the carrier according to the ratio and stirring to obtain mixed liquid; (2) condensing 
fog-like materials in a collecting room to obtain microspheres; and (3) collecting the microspheres and screening the microspheres by virtue of a screen to obtain the microspheres with required diameters; disinfecting, sealing and packaging the microspheres.