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33 results about "Oral Microflora" patented technology

Application of lactobacillus paracasei L9 to prevention or treatment oral disease and regulation of oral cavity flora

The invention discloses an application of lactobacillus paracasei L9 to prevention or treatment oral disease and regulation of oral cavity flora. L9 can be used for preparing a medical composition anda food for preventing or treating dental caries. Research proves that L9 can notably relieve generation degree of occlusal surface E-level dental caries, after the LP is taken, the structure of the oral cavity flora is changed notably, particularly actinobacteria is notably increased, the actinobacteria of L9 group is obviously reduced, klebsiella, aerococcus, Gemella, corynebacterium and pseudomonas aeruginosa on the classification level are notably reduced, and the oral disease risk is reduced. When L9 is taken, the saliva species richness is notably reduced, the relative abundance of oraldisease relevant fungi of streptococcus salivarius, actinomycetaceae, peptostreptococcus and the like is notably reduced, and the L9 can have relieving effects on periodonitis diseases. The dental plaque flora species diversity is notably reduced, the relative abundance of leptothrix, fusobacteriaceaeand flavobacterium is notably reduced, and the L9 can have relieving effects on oral diseases of periodontal disease, halitosis, dental caries and the like.
Owner:BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY

Composition with oral cavity health care function and preparing method and application thereof

The invention relates to the technical field of daily chemical products, in particular to a composition with an oral cavity health care function and a preparing method and application thereof. The composition comprises glycyrrhetinic acid, a herba taraxaci extract, totarol and a krameria triandra extract. According to the composition, different medicinal mechanisms of various components are utilized, the glycyrrhetinic acid, the herba taraxaci extract and the totarol are compounded and further supplemented with the krameria triandra extract, and thus full is given to the synergistic effects ofall the components. In the meanwhile, effective components which are hard to dissolve, disperse and absorb are subjected to nanocrystallization, so that the absorptivity and bioavailability of the components by the mouth mucosa are significantly increased, and it is guaranteed that the effective components play a synergistic effect to the greatest extent. The obtained composition has the functions of inhibiting helicobacter pylori and other bacteria harmless to the oral cavity, maintaining the balance of the flora of the oral cavity, and preventing and relieving gingival bleeding, gingivitisand inflammations of the oral cavity; meanwhile, the composition has the advantages of being natural in raw material, wide in source, safe to the human body, low in cost, convenient to produce and thelike.
Owner:沈阳天然纳美科技有限公司

Chinese herbal medicine plant oral care composition and preparation method and application method thereof

InactiveCN110575414ARegulate and restore micro-ecological balanceReduce and prevent looseningCosmetic preparationsToilet preparationsChlorogenic acidAdditive ingredient
The invention relates to a Chinese herbal medicine plant oral care composition, and a preparation method and an application method thereof. The composition is prepared from the following raw materials: sorbitol, hydrated silica, water, polyethylene glycol-8, sodium lauryl sulfate, essence, a Chinese herbal medicine extract, methyl hydroxybenzoate, cellulose gum, CI77891, sodium saccharin, tetrasodium pyrophosphate, and zinc citrate. The ingredients of the above Chinese herbal medicine extract are prepared from the following raw materials: pubescent holly root, rhizoma anemarrhenae, Chinese angelica, pseudo-ginseng, cortex moutan, gentiana macrophylla, rhzizoma drynariae, cortex lycii radicis, sarcandra glabra, and Chamaemelum nobile. The preparation process of the invention is simple. Since the Chinese herbal medicine extract contains various natural plant organic acids, trace elements, minerals, chlorogenic acid and flavonoids compounds, the Chinese herbal medicine plant oral care composition has antibacterial, antiviral, anti-inflammatory and free radical removal effects, and can effectively inhibit harmful bacteria, cultivate beneficial flora, condition and repair oral microflora micro-ecological balance and fundamentally reduce and prevent and treat various oral problems if being used for a long time.
Owner:广州医家仁生物科技有限责任公司

FBA oral flora functional group obtained based on microbial functional group mining method

PendingCN113012810AEffectively reflect stabilityHealth-index calculationSurgeryBiotechnologyOral disease
The invention relates to the field of biological information technology and medical health, and discloses a concept, thought and method for mining a community functional group based on the network analysis technology, and an FBA functional group found from a healthy human oral flora. The functional group is mainly composed of bacteria of the phylum F, the phylum B and the phylum A of actinobacteria, the whole functional group is of a structure that the phylum F and the phylum B synergistically inhibit the phylum A, and the functional group is generally a module with the most species number and the highest density in a healthy oral cavity network. Specifically, the functional group is composed of two sub-functional groups (Sub-Guld), wherein one of the sub-functional groups is mainly composed of F and B mycophylum bacteria, and the other one of the sub-functional groups is mainly A mycophylum bacteria. Species in the two sub-functional groups are in a synergistic relationship, but the two sub-functional groups are in a complete antagonistic competition relationship. The FBA functional group can effectively reflect the stability of the environment in the oral cavity, and a biological foundation is laid for oral health and oral disease healing condition monitoring.
Owner:KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI

Helicobacter pylori toothpaste and preparation method and device thereof

The invention relates to the technical field of toothpaste preparation, in particular to helicobacter pylori toothpaste and a preparation method and device thereof.The helicobacter pylori toothpaste is prepared from, by mass, forsythiaside, fagopyrin, tea polyphenol, glycyrrhetinic acid, lactoferrin, hydrated silica, sorbitol, glycerin, purified water, herbal extracts and essence. Comprising a supporting frame, a fixing rod, a connecting ring, a feeding pipe, a blending bag, an abutting assembly, a mixing module and a scraping assembly, the fixing rod is fixedly connected with the supporting frame, the feeding pipe is fixedly connected with the connecting ring, the feeding pipe is communicated with the blending bag, the scraping assembly comprises a sliding rail, a sliding block, a connecting strip and a scraping strip, the sliding rail is fixedly connected with the blending bag, the connecting strip is fixedly connected with the sliding block, and the scraping strip is fixedly connected with the sliding block. The prepared helicobacter pylori toothpaste has the characteristics of diminishing inflammation and maintaining the balance of oral flora, the production of production personnel is facilitated, and the production efficiency is improved.
Owner:南京健邦锦源医疗科技有限公司

A gum base composition for protecting oral flora balance and preparation method thereof

The invention relates to a gum base composition for protecting the balance of oral flora. The gum-based composition is prepared from a gum base, bioactivity mineral powder and polylysine, wherein a weight proportion of the bioactivity mineral powder and the polylysine is (2 to 25) : (0.0003 to 10). According to the gum base composition disclosed by the invention, the bioactivity mineral powder and the polylysine in the gum base composition are capable of inhibiting and killing various pathogenic bacteria in an oral cavity, preventing and treating oral problems of oral infection, oral ulcer, chronic gingisitis and the like, and have long-acting bacteria resistance; meanwhile, the bioactivity mineral powder and the polylysine have a certain selective protection function on beneficial bacteria in the oral cavity, the balance of flora in the oral cavity can be effectively regulated, and normal sanitation and health of the oral cavity can be maintained. Through remineralization of the bioactivity mineral powder on teeth, the gum base composition is capable of effectively repairing dentin defects; the gum base composition provided by the invention is convenient to use, wide in receiver groups and very strong in market application value.
Owner:北京刷新活力健康科技有限公司

Toothpaste with antibacterial and bacteriostatic effects for adjusting oral flora and preparation method thereof

The invention belongs to the technical field of daily necessities, and particularly relates to toothpaste with antibacterial and bacteriostatic effects and capable of adjusting oral flora and a preparation method of the toothpaste, and the toothpaste comprises a toothpaste body and a toothpaste tube for containing the toothpaste body. The toothpaste tube is squeezed through the two rotating squeezing rods, it is guaranteed that the squeezing rods can roll over the surface of the toothpaste tube, no non-squeezed part exists, it is guaranteed that the remaining toothpaste body in the toothpaste tube can be almost completely squeezed out, waste of the toothpaste body is reduced, and the toothpaste body in the toothpaste tube can be fully utilized; the natural extract is adsorbed in the pore structure of the active carbon, the active carbon can be uniformly dispersed after the active carbon is mixed with other raw materials to prepare the toothpaste, the natural extract in the pores can give full play to the antibacterial activity and desensitization acid-proof activity, and the active carbon has very good stability, so that the natural extract can continuously give play to the antibacterial activity, and the toothpaste can be used for preparing the toothpaste. Therefore, the antibacterial performance, the antibacterial durability and the desensitization acid-proof performance of the toothpaste are greatly improved.
Owner:STOMATOLOGY AFFILIATED STOMATOLOGY HOSPITAL OF GUANGZHOU MEDICAL UNIV

Application of black raspberry lyophilized powder in preparing drug for inhibiting oral diseases

The invention relates to application of black raspberry lyophilized powder in preparing a drug for inhibiting oral diseases. The black raspberry lyophilized powder or an extract of the powder as an active ingredient is in combination with a pharmaceutically acceptable adjuvant to form a pharmaceutical preparation. The adjuvant comprises, by weight, 83-93% of black raspberry lyophilized powder or the extract, 1-5% of maltodextrin, 2-6% of filler, 1-5% of disintegrant and 1-4% of lubricant. The pharmaceutical preparation has small adjuvant amount, uniform dispersion of active ingredients, good stability and high bioavailability, can effectively inhibit the growth of pathogenic bacteria, maintain the balance of oral flora and further improve generation and development of poor oral breath likeozostomia.
Owner:LIAONING UNIVERSITY

Traditional Chinese medicine composition for oral cavity bacteriostasis and preparation method thereof

The invention relates to the technical field of traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for oral cavity bacteriostasis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine main materials and auxiliary materials in parts by weight: the main materials comprise 0.1 to 5 parts of chrysanthemum, 0.1 to 3 parts of flos lonicerae, 0.1 to 3 parts of fructus aurantii, 0.01 to 1 part of menthol, and the balance of the auxiliary materials; and the auxiliary materials are selected from purified water, glycerol and potassium sorbate in a ratio of 200: 1: 1. According to the traditional Chinese medicine composition for oral cavity bacteriostasis and the preparation method thereof, by inhibiting halitosis pathogenic bacteria in an oral cavity, halitosis is effectively removed, meanwhile, gingiva and oral health can be protected, the morbidity rate of caries, periodontal diseases and the like of a user is reduced, oral flora is not prone to being damaged, and the problem of new diseases caused by oral flora imbalance easily caused by long-term use of existing mouthwash is solved.
Owner:贵州医之星药业有限公司
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