8 results about "Antacid" patented technology

An aspect provides a pharmaceutical composite formulation containing: a first layer comprising a proton pump inhibitor or a pharmaceutically acceptable salt thereof as an active ingredient, a disintegrant, and a binder; and a second layer comprising, as an active ingredient, an antacid selected from magnesium hydroxide, magnesium oxide, or a mixture thereof.

The invention relates to the field of medicines for treating oral inflammations, and provides a PANX1 / P2X7R antagonist and application thereof in preparation of a medicine for treating oral inflammations through a synergistic effect with red laser irradiation. Wherein the PANX1 / P2X7R antagonist comprises a sulfonated triphenylmethane dye, a gel material, an antacid, a humectant, a preservative, a solvent and other acceptable components. Wherein the first application is the application of the PANX1 / P2X7R antagonist in preparation of medicines for treating oral inflammation; the second application is the application of the PANX1 / P2X7R antagonist in preparation of a medicine for treating oral inflammation under the synergistic effect with red laser irradiation; the PANX1 / P2X7R antagonist is combined with red laser irradiation to serve as a regulator of ATP inside and outside cells, and remarkable synergistic anti-inflammatory, anti-oxidation, antibacterial and repair-promoting effects are shown.

The objective is to provide an additive for mushroom culture media that can reduce weighing errors and improve the uniform mixing of antacids in the culture media. [Solution] The mushroom culture medium additive of this disclosure comprises a bulking agent and an antacid.

This invention relates to coated soft chewable tablets, the soft chewable tablets comprising: a core, in an amount of 60% to 99% by weight of the soft chewable tablet, the core forming a cohesive, unheated mass and comprising: one or more water-soluble fibers, in an amount of 10% to 45% by weight of the core; one or more powdered monosaccharides and / or disaccharides, in an amount of 10% to 45% by weight of the core; one or more texture agents, in an amount of 0.1% to 15% by weight of the core; one or more active ingredients, in an amount of 1% to 60% by weight of the core; and one or more solid syrups, in an amount of up to 20% by weight of the core; and an outer coating surrounding the core, in an amount of 1% to 40% by weight of the soft chewable tablet.

The invention discloses a gastric acid resistant astaxanthin ester microcapsule and a preparation method thereof, and belongs to the technical field of astaxanthin ester processing and preparation. The preparation method comprises the following steps: dispersing starch octenyl succinate in water, gelatinizing, cooling, mixing with a chitosan solution, adding a sodium chloride solution, and freeze-drying to obtain rigid nanoparticles; dissolving natural astaxanthin ester in the oil phase to obtain astaxanthin ester oil; the preparation method comprises the following steps: dissolving rigid nanoparticles in water, adding astaxanthin ester oil, and shearing to obtain an astaxanthin ester emulsion; and mixing with a wall material solution, and carrying out spray drying to obtain the gastric acid-resistant astaxanthin ester microcapsule. The prepared astaxanthin ester microcapsule has gastric acid resistance stability, degradation of astaxanthin ester in the digestion and absorption process is reduced, more astaxanthin ester reaches the small intestine stage to be absorbed into the body, and the utilization efficiency of astaxanthin is improved. The preparation method is simple in preparation process, does not use a small molecular surfactant in the process, is green and safe, and can be efficiently applied to the field of functional foods.

This invention discloses a gelling material for treating gastric diseases and its preparation method, belonging to the field of pharmaceutical preparation technology. The gelling material is composed of 8-10g of Codonopsis pilosula extract, 6-10g of Bletilla striata extract, 6-8g of Dioscorea opposita extract, 2-4g of Citrus reticulata peel extract, 2-3g of gelatin, 2-4g of xylitol, 0.1-0.2g of citric acid, and 60.8-73.9g of purified water. As a carrier matrix, the gelling material of this invention exhibits good compatibility with commonly used antacids (such as calcium carbonate), PPIs (such as omeprazole), antibiotics (such as amoxicillin and clarithromycin), and traditional Chinese medicine extracts. During preparation, the above-mentioned active pharmaceutical ingredients (APIs) can be uniformly dispersed in the gel matrix, achieving integrated synergistic treatment of "mucosal protection + acid suppression / bactericidal action" without compromising their chemical stability or causing burst release problems, providing an ideal platform for developing compound gastric disease preparations.

The invention discloses an absorbable tissue strengthening material loaded with an antacid agent and a preparation method of the absorbable tissue strengthening material, and belongs to the technical field of biomedical materials. The invention is used for solving the problems of postoperative wound ulcer, difficulty in healing and the like caused by the side effect of taking aspirin or other NSAIDs for a long time after an ESD (Electro-Static Discharge) operation of a patient who suffers from an early gastric tumor and needs to be subjected to ESD treatment and anti-thrombus treatment at the same time in the prior art. The invention provides a preparation method of an absorbable tissue reinforcing material loaded with an anti-acid agent, which comprises the following steps: S1, mixing a polymer resin material and the anti-acid agent, and carrying out melt extrusion to form a composite melt trickle; cooling the composite melt trickles to form nascent filaments; s2, drafting and shaping the nascent filaments, and stripping and splitting the nascent filaments by adopting high-pressure water flow to prepare a polymer resin / antacid composite net; and cutting the polymer resin / antacid composite net to prepare the absorbable tissue reinforcing material loaded with the antacid.

The present invention relates to a pharmaceutical combination preparation comprising ilaprazole, an antacid, and an alkalizing agent and, more specifically, to a pharmaceutical combination preparation and a method for preparing same, wherein decomposition of ilaprazole in the stomach is prevented without enteric coating to improve stability, thereby increasing bioavailability, and the quality and productivity of pharmaceutical products are improved due to uncomplicated manufacturing processes and excellent storage stability of the preparation.