Magnetic polymer nanocapsules suitable for therapy, in particular anti-cancer therapy
By developing magnetic polymer nanocapsules based on liquid oil cores, the problems of low encapsulation efficiency and poor targeting of hydrophobic active substances in the prior art are solved, and efficient, selective targeting and controlled release to cancer cells is achieved, reducing the side effects of anti-cancer therapy.
Patent Information
- Application Number
- CN202380072570.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Priority Date
- 2022-08-11
- Filing Date
- 2023-08-11
- Publication Date
- 2025-08-12
AI Technical Summary
The polymer nanocapsules with high stability and magnetic properties in the prior art are used in anti-cancer therapy, resulting in low encapsulation efficiency, insufficient release concentration, poor targeting, and side effects, and the existing system size is large and difficult to penetrate cancer cells.
Magnetic polymer nanocapsules based on liquid oil cores are developed, containing magnetic iron oxide nanoparticles and hydrophobic active substances. Through static magnetic field navigation and alternating magnetic field release, efficient targeted delivery is achieved. The capsule size is small and has good biocompatible.
It achieves efficient encapsulation and release of hydrophobic active substances to cancer cells, avoids toxicity to normal cells, provides selective targeting and controlled release, and reduces the side effects of anti-cancer therapy.