3 results about "Aconitum carmichaelii" patented technology

This invention provides a traditional Chinese medicine composition for treating anxiety, depression, and / or sleep disorders, its preparation method, and its application, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition includes the following raw materials: *Aconitum carmichaelii* root slices, calcined magnetite, stir-fried jujube seed, prepared polygala tenuifolia root, prepared pinellia tuber, tangerine peel, stir-fried immature bitter orange, ginger-processed bamboo shavings, albizia bark, poria cocos, coix seed, bamboo leaf bupleurum root, oyster shell, licorice root, and dragon bone. The preparation method includes: first decocting the *Aconitum carmichaelii* root slices, then adding the remaining medicinal ingredients and decocting with water; concentrating the filtrate into a clear paste, adding excipients, and compressing into tablets. Animal experiments show that, compared with the model group, the traditional Chinese medicine composition of this invention can significantly increase the number of times mice enter the central region and the dwell time in the open field test, and improve the number of times mice enter the open arms of the elevated cruciate maze and the dwell time; hippocampal Nielsen staining shows that neurons are neatly arranged and cell density is well restored. This invention has the effects of warming the kidney and suppressing yang, resolving phlegm and calming the mind, and can be used to prepare drugs for treating anxiety, depression, and / or sleep disorders.

This invention provides a traditional Chinese medicine preparation for treating Hashimoto's thyroiditis and its preparation method, belonging to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from Curcuma zedoaria, oyster shell, Eclipta prostrata, Ligustrum lucidum, Sargassum, processed Aconitum carmichaelii, Cremastra appendiculata, Duchesnea indica, Hedyotis diffusa, Artemisia capillaris, Oroxylum indicum, and cinnamon. The formula is meticulously formulated, closely addressing the core pathogenesis of Hashimoto's thyroiditis: "phlegm and blood stasis, spleen and kidney deficiency, and nutritional imbalance." It focuses on "eliminating masses and dispersing nodules, promoting qi and blood circulation," fully embodying the TCM diagnostic and treatment approach of "differentiating syndromes and treating accordingly, addressing both the root cause and symptoms." This invention's preparation has a good therapeutic effect on Hashimoto's thyroiditis, effectively improving thyroid autoimmune disorders, regulating thyroid function, and alleviating symptoms of local thyroid inflammation in experimentally induced Hashimoto's thyroiditis rats. Further clinical observation studies have found that this preparation significantly improves the overall effective rate of clinical treatment for Hashimoto's thyroiditis patients, providing a new approach to the treatment of this condition.

This invention relates to the technical field of traditional Chinese medicine compounds, specifically a diterpenoid alkaloid compound for preventing and treating root rot in Codonopsis pilosula. The diterpenoid alkaloid compound is neoaconitine, and its structural formula is shown in Figure 1. The neoaconitine is a white amorphous powder. 1 H-NMR signals included three groups of hydrogen atoms on the aromatic ring, one monosubstituted acetyl group, four methoxy hydrogen atoms, and one group of N-methyl hydrogen atoms. 13 C-NMR has a specific chemical shift value. This invention has a strong inhibitory effect on Fusarium oxysporum, the pathogen causing root rot in Codonopsis pilosula, and can effectively inhibit the growth and reproduction of pathogenic mycelia, blocking the occurrence and spread of the disease from the source, significantly reducing the incidence and severity of root rot in Codonopsis pilosula, ensuring the normal growth of Codonopsis pilosula, and improving yield and quality.