Chinese patent medicine external application ointment for treating pain in neck, shoulder, waist and lower extremities and preparation method of Chinese patent medicine external application ointment

Abstract

The invention belongs to the technical field of Chinese patent medicine external application ointment, and discloses Chinese patent medicine external application ointment for treating neck, shoulder, waist and leg pain and a preparation method of the Chinese patent medicine external application ointment. The external application paste is prepared from the following raw materials in parts by weight: 20-25 parts of kadsura longepedunculata leaves, 12-16 parts of kadsura longepedunculata roots, 10-15 parts of helwingia himalayana, 10-15 parts of ainsliaea insignis, 10-15 parts of paris polyphylla, 10-15 parts of rhizoma bletillae, 10-15 parts of frankincense, 10-15 parts of myrrh, 10-15 parts of rheum officinale, 12-16 parts of cortex phellodendri chinensis, 10-15 parts of radices trichosanthis, 6-12 parts of radix angelicae, 10-15 parts of scutellaria baicalensis, 6-12 parts of purpleflower holly leaves, 3-9 parts of liquorice, 6-10 parts of radix aconiti kusnezoffii and 9-12 parts of radix aconiti The preparation method comprises the following steps: weighing the raw materials, grinding into superfine powder, and uniformly mixing; and adding yellow wine, and stirring into a thick state so as to be conveniently coated on an affected part. The invention solves the problems of single medicinal composition, slow effect and unsatisfactory treatment effect of the existing external application paste.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine external application plasters, and specifically relates to a traditional Chinese medicine external application plaster for treating neck, shoulder, waist and leg pain and a preparation method thereof. Background Art

[0002] Neck, shoulder, waist and leg pain is a common clinical syndrome, mainly including diseases such as cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, lumbar muscle strain, knee arthritis, etc. Its pathogenesis is complex, and it is mostly related to factors such as invasion of wind, cold and damp pathogens, strain, trauma, etc., resulting in meridian blockage, poor qi and blood circulation, and loss of nourishment for muscles and bones. At present, there are many clinical treatment methods for neck, shoulder, waist and leg pain, including drug treatment, physical therapy, surgical treatment, etc.

[0003] Among them, external application plasters are widely used in the treatment of neck, shoulder, waist and leg pain due to their advantages such as convenient use and small side effects. However, the existing external application plasters still have certain limitations in terms of treatment effect, safety, etc., and the medicinal components are single and the onset is slow. Therefore, it is urgent to develop an external application plaster with significant curative effect and high safety. Summary of the Invention

[0004] The present invention aims to provide a traditional Chinese medicine external application plaster for treating neck, shoulder, waist and leg pain and a preparation method thereof, which solves the problems of single medicinal components, slow onset and unsatisfactory treatment effect of the existing external application plasters.

[0005] In order to achieve the above purpose, the present invention provides the following technical solutions:

[0006] A traditional Chinese medicine external application plaster for treating neck, shoulder, waist and leg pain is made from the following raw materials in parts by weight: 20 - 25 parts of Sargentodoxa cuneata leaves, 12 - 16 parts of Sargentodoxa cuneata roots, 10 - 15 parts of Helwingia himalaica, 10 - 15 parts of Helwingia japonica, 10 - 15 parts of Paris vietnamensis, 10 - 15 parts of Bletilla striata, 10 - 15 parts of frankincense, 10 - 15 parts of myrrh, 10 - 15 parts of Rheum officinale, 12 - 16 parts of Phellodendron amurense var. sutchuenense, 10 - 15 parts of Trichosanthes kirilowii Maxim., 6 - 12 parts of Angelica dahurica, 10 - 15 parts of Scutellaria baicalensis Georgi, 6 - 12 parts of Ilex purpurea Hassk., 3 - 9 parts of Glycyrrhiza uralensis Fisch., 6 - 10 parts of Aconitum carmichaelii Debx., 9 - 12 parts of Aconitum kusnezoffii Reichb.

[0007] Further, it is made from the following raw materials in parts by weight: 21 parts of Sargentodoxa cuneata leaves, 15 parts of Sargentodoxa cuneata roots, 12 parts of Helwingia himalaica, 12 parts of Helwingia japonica, 12 parts of Paris vietnamensis, 12 parts of Bletilla striata, 12 parts of frankincense, 12 parts of myrrh, 12 parts of Rheum officinale, 15 parts of Phellodendron amurense var. sutchuenense, 15 parts of Trichosanthes kirilowii Maxim., 9 parts of Angelica dahurica, 12 parts of Scutellaria baicalensis Georgi, 9 parts of Ilex purpurea Hassk., 6 parts of Glycyrrhiza uralensis Fisch., 9 parts of Aconitum carmichaelii Debx., 12 parts of Aconitum kusnezoffii Reichb.

[0008] According to the above-mentioned preparation method of a traditional Chinese medicine external application plaster for treating neck, shoulder, waist and leg pain, it includes the following steps:

[0009] S1. Weigh the leaves and roots of Sargentodoxa cuneata, the flowers above and below the leaves, Paris polyphylla, Bletilla striata, frankincense, myrrh, rhubarb, Phellodendron amurense, Trichosanthes kirilowii, Angelica dahurica, Scutellaria baicalensis, Ilex purpurea, liquorice, Aconitum carmichaelii and Aconitum kusnezoffii, grind them into extremely fine powder, and mix them evenly.

[0010] S2. Add yellow rice wine and stir evenly to form a viscous state for easy application on the affected area.

[0011] The beneficial effects of the technical solution are as follows:

[0012] The present invention provides a preparation method of a traditional Chinese medicine external application plaster for treating neck, shoulder, waist and leg pain. The leaves / roots of Sargentodoxa cuneata: Soothe the muscles and activate collaterals, reduce swelling and relieve pain, mainly regulate rheumatic arthralgia; the flowers above / below the leaves: Expel wind and dampness, activate blood circulation and dredge collaterals, improve joint stiffness and pain; Paris polyphylla: Clear heat and detoxify, reduce swelling and relieve pain, inhibit inflammatory reactions; Bletilla striata: Bletilla striata has the effects of astringing bleeding, reducing swelling and promoting granulation; frankincense / myrrh: Activate blood circulation and promote qi movement, disperse stasis and relieve pain, promote local blood circulation; rhubarb: Remove blood stasis and dredge meridians, clear heat and dissipate stasis, remove blood stasis and relieve pain; Phellodendron amurense: Clear heat and purge fire, cool blood and detoxify, reduce tissue edema; Trichosanthes kirilowii: Trichosanthes kirilowii has the effects of clearing heat and purging fire, reducing swelling and discharging pus; Angelica dahurica: Angelica dahurica relieves exterior syndrome by diaphoresis, dispels wind and relieves pain, opens orifices, reduces swelling and discharges pus; Scutellaria baicalensis: Scutellaria baicalensis clears heat and dries dampness, purges fire and detoxifies, can inhibit the production and release of inflammatory factors in the body, and helps to eliminate local damp-heat pathogens; Ilex purpurea: Ilex purpurea clears heat and detoxifies, cools blood and stops bleeding, heals sores; Aconitum carmichaelii / Aconitum kusnezoffii: Expel wind and dampness, warm meridians and relieve pain, quickly relieve severe pain; liquorice: Harmonize all the drugs, alleviate toxicity, and enhance the synergistic effect.

[0013] The formula of this plaster has been clinically verified by several people. For diseases such as low back pain, leg pain, lumbar disc herniation, cervical spondylosis, and muscle injury, it has definite and stable therapeutic effects. The medicinal components of the plaster are diverse, with a fast onset of action and good therapeutic effects. In the formula, the leaves of Sargentodoxa cuneata are paired with the roots of Sargentodoxa cuneata, which can penetrate deep into the tendons and meridians and quickly soothe the pain caused by strain, cold and dampness; Aconitum carmichaelii and Aconitum kusnezoffii are precisely formulated to exert a powerful effect of warming meridians and relieving pain, quickly curb the pain symptoms, and cooperate with liquorice to reconcile and reduce toxicity to ensure the safety of medication. After patients use this plaster, the drug components can penetrate through the skin and be absorbed through acupoints, and can quickly take effect within about two hours, rapidly relieving the pain symptoms. Frankincense and myrrh activate blood circulation and promote qi movement, while rhubarb and Phellodendron amurense clear heat and reduce swelling. The synergistic effect of multiple medicinal materials can not only quickly relieve pain, but also improve local blood circulation and inflammatory state, continuously play the role of reducing swelling and relieving pain, repairing injuries, and consolidating the therapeutic effect.

[0014] The effects of the medicinal materials in the formula complement each other, and they act on the pathogenesis of various diseases such as neck, shoulder, waist and leg pain. Huperzia serrata and Phyllanthus simplex can dispel wind and dampness, dredge collaterals and relieve pain, and are applicable to rheumatic low back pain and leg pain; Paris polyphylla and Bletilla striata have a good effect of detumescence and promoting granulation growth on the swelling, redness, heat and pain after muscle injury; medicinal materials such as Angelica dahurica and Scutellaria baicalensis can improve symptoms such as dizziness and numbness of the upper limbs caused by cervical spondylosis, achieving multiple treatments with one medicine and meeting the needs of different patients.

[0015] This plaster uses natural Chinese medicinal materials as raw materials and is administered externally, avoiding the irritation to the gastrointestinal tract and the first-pass effect of the liver caused by oral drugs. At the same time, through reasonable compatibility of medicinal materials and dose control, the risk of adverse reactions is greatly reduced. The effective rate in clinical application reaches 95%, and it has good safety and is suitable for long-term use. Specific implementation mode

[0016] The present invention will be further described in detail below in conjunction with the implementation mode:

[0017] Example 1

[0018] A traditional Chinese medicine external plaster for treating neck, shoulder, waist and leg pain is made from the following raw materials by weight: 21g of Sargentodoxa cuneata leaves, 15g of Sargentodoxa cuneata roots, 12g of Huperzia serrata, 12g of Phyllanthus simplex, 12g of Paris polyphylla, 12g of Bletilla striata, 12g of frankincense, 12g of myrrh, 12g of rhubarb, 15g of Phellodendron amurense, 15g of Trichosanthes kirilowii Maxim., 9g of Angelica dahurica, 12g of Scutellaria baicalensis, 9g of Ilex purpurea Hassk., 6g of Glycyrrhiza uralensis Fisch., 9g of Aconitum carmichaelii Debx., and 12g of Aconitum kusnezoffii Reichb. Among them, frankincense and myrrh have been processed by vinegar processing, which can change or enhance the properties of the drugs, enhance the curative effect and reduce irritation;

[0019] The preparation method includes the following steps:

[0020] S1. Weigh 21g of Sargentodoxa cuneata leaves, 15g of Sargentodoxa cuneata roots, 12g of Huperzia serrata, 12g of Phyllanthus simplex, 12g of Paris polyphylla, 12g of Bletilla striata, 12g of frankincense, 12g of myrrh, 12g of rhubarb, 15g of Phellodendron amurense, 15g of Trichosanthes kirilowii Maxim., 9g of Angelica dahurica, 12g of Scutellaria baicalensis, 9g of Ilex purpurea Hassk., 6g of Glycyrrhiza uralensis Fisch., 9g of Aconitum carmichaelii Debx., and 12g of Aconitum kusnezoffii Reichb., grind them into extremely fine powder, and mix evenly;

[0021] S2. Add yellow rice wine and stir evenly into a viscous state for easy application to the affected area; the weight ratio of yellow rice wine to the evenly mixed traditional Chinese medicine powder is 1:1.

[0022] When in use, according to the actual situation of the patient, take the viscous plaster and directly apply it on the corresponding part or acupoint, and then wrap it with an acupoint patch or gauze and fix it on the skin. For example, for parts such as the knee joint, the drug can be fixed with gauze wrapping; specific acupoints can be wrapped and fixed with an acupoint patch.

[0023] Example 2

[0024] The differences between this embodiment and Embodiment 1 are as follows: The components and weights of each raw material are: 20 g of Sarcandra glabra leaves, 16 g of Sarcandra glabra roots, 14 g of Helwingia himalaica, 14 g of Helwingia japonica, 14 g of Paris vietnamensis, 14 g of Bletilla striata, 13 g of frankincense, 13 g of myrrh, 13 g of Rheum officinale, 15 g of Phellodendron amurense var. sutchuenense, 12 g of Trichosanthes kirilowii, 10 g of Angelica dahurica, 14 g of Scutellaria baicalensis, 12 g of Ilex purpurea, 5 g of Glycyrrhiza uralensis, 8 g of Aconitum carmichaelii, and 10 g of Aconitum kusnezoffii.

[0025] Embodiment 3

[0026] The differences between this embodiment and Embodiment 1 are as follows: The components and weights of each raw material are: 22 g of Sarcandra glabra leaves, 16 g of Sarcandra glabra roots, 10 g of Helwingia himalaica, 10 g of Helwingia japonica, 10 g of Paris vietnamensis, 13 g of Bletilla striata, 13 g of frankincense, 10 g of myrrh, 10 g of Rheum officinale, 12 g of Phellodendron amurense var. sutchuenense, 15 g of Trichosanthes kirilowii, 8 g of Angelica dahurica, 12 g of Scutellaria baicalensis, 10 g of Ilex purpurea, 8 g of Glycyrrhiza uralensis, 8 g of Aconitum carmichaelii, and 10 g of Aconitum kusnezoffii.

[0027] Examples of the usage effects of the plaster in Embodiment 1:

[0028] 1. Fan Xiaohua, female

[0029] Date of visit: April 8, 2022

[0030] Patient's symptoms: 2 months after lumbar 4-5 foraminal endoscopic surgery, there was low back pain after the surgery, and there was no change in the numbness of the left lower limb, so she came to our clinic for treatment. There was obvious lumbosacral pain, difficulty standing and walking for a long time, swelling pain in the lower leg of the left lower limb, and obvious numbness on the lateral side of the lower leg. Magnetic resonance imaging showed a lumbar 4-5 intervertebral disc herniation (mild degree);

[0031] Patient's usage effect: Apply one plaster at the lumbar 4-5 position. After two days, she reported that the low back pain was significantly relieved. After continuously applying five plasters, she reported that there was no obvious feeling of low back pain, the numbness of the left lower limb improved, and there was a slight swelling feeling in the anterolateral part of the lower leg, and no other discomfort was reported;

[0032] Effect cycle: 8 days

[0033] 2. Wu Wei, male

[0034] Date of visit: March 2023

[0035] Patient's symptoms: A professional athlete, due to long-term load and fatigue, multiple tendons in the right ankle were slightly torn. Now, there is obvious pain in the ankle joint, and symptoms are present in both the lateral and medial malleoli;

[0036] Patient's usage effect: After applying the plaster 3 times, he reported that the pain was relieved and the pain during training was reduced;

[0037] Effect cycle: 3 days

[0038] 3. Yin Lihua, female

[0039] Medical visit time: April 2024

[0040] Patient's symptoms: The patient has breast cancer and a definite history of cancer. She complains of pain in the lumbosacral region, with obvious pain when getting up after sitting for a long time and bending down. There are no symptoms in the lower limbs;

[0041] Patient's usage effect: She reported significantly reduced pain on the second day after applying one patch, and then continued the 7-day patch application treatment course;

[0042] Effect cycle: 7 days

[0043] 4. Liao Shibi, female

[0044] Medical visit time: March 2025

[0045] Patient's symptoms: History of femoral head necrosis. She complains of pain in the right hip and pain on the inner edge of the left knee. The joints are significantly deformed. Consider femoral head necrosis and osteoarthropathy;

[0046] Patient's usage effect: After applying one patch, she reported reduced pain in the right hip at night. After continuously applying three patches, she reported improved pain in the hip and knee joints and improved walking ability;

[0047] Effect cycle: 4 days

[0048] 5. Zou Kaigui, male

[0049] Medical visit time: April 15, 2025

[0050] Patient's symptoms: The patient complains of low back pain and numbness in both lower limbs. Magnetic resonance imaging shows severe lumbar disc herniation at L4-L5 and L5-S1, combined with spinal canal stenosis. The treatment effect outside the hospital is not good;

[0051] Patient's usage effect: She reported reduced low back pain after applying the patch for three days. After cooperating with other treatments, she reported relieved numbness and improved mobility, and continued to apply the medicine twice;

[0052] Effect cycle: 5 days

[0053] In summary, the formula of this plaster has been clinically verified by several people. It has definite and stable therapeutic effects on diseases such as low back pain, leg pain, lumbar disc herniation, cervical spondylosis, and muscle injuries. The formula of this plaster has been clinically verified by several people. It has definite and stable therapeutic effects on diseases such as low back pain, leg pain, lumbar disc herniation, cervical spondylosis, and muscle injuries. The medicinal components of the plaster are diverse, with a fast onset of action and good therapeutic effects. In the formula, the leaves of Sargentodoxa cuneata var. enneaphylla are paired with Sargentodoxa cuneata, which can penetrate deep into the tendons and veins and quickly relieve the pain caused by strain, cold, and dampness. Prepared Aconite Root and Kusnezoff Monkshood Root are precisely formulated to exert a powerful effect of warming the meridians and relieving pain, quickly curbing the pain symptoms, and are combined with Licorice Root to reconcile and reduce toxicity to ensure the safety of medication. After patients use this plaster, the drug components can penetrate through the skin and be absorbed through acupoints, and can quickly take effect within about two hours, rapidly relieving the pain symptoms. Frankincense and Myrrh promote blood circulation and activate qi, and Rhubarb and Amur Cork Tree Bark clear heat and reduce swelling. The synergistic effect of multiple medicinal materials can not only quickly relieve pain, but also improve local blood circulation and inflammatory state, continuously play the role of reducing swelling and relieving pain, repairing injuries, and consolidating the therapeutic effect.

[0054] The effects of each medicinal material in the formula complement each other and play a role in the pathogenesis of various diseases of neck, shoulder, low back and leg pain. Chloranthus multistachys Wall. var. laxus Hand.-Mazz. and Chloranthus multistachys Wall. dispel wind and dampness, dredge collaterals and relieve pain, and are suitable for rheumatic low back pain and leg pain; Paris vietnamensis (Takht.) H. Li and Bletilla striata (Thunb.) Reichb. f. have a good effect of reducing swelling and promoting granulation growth on the red, swollen, hot and painful symptoms after muscle injury; medicinal materials such as Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav. and Scutellaria baicalensis Georgi can improve symptoms such as dizziness and numbness of the upper limbs caused by cervical spondylosis, achieving multiple treatments with one medicine and meeting the needs of different patients.

[0055] This plaster uses natural Chinese medicinal materials as raw materials and is administered externally, avoiding the irritation of oral drugs to the gastrointestinal tract and the first-pass effect of the liver. At the same time, through reasonable compatibility of medicinal materials and dose control, the risk of adverse reactions is greatly reduced. The effective rate in clinical application reaches 95%, and it has good safety and is suitable for long-term use.

[0056] The above are only examples of the present invention. Specific technical solutions or common knowledge such as characteristics known in the solution are not described in detail here. It should be noted that for those skilled in the art, without departing from the technical solution of the present invention, several deformations and improvements can still be made, which should also be regarded as the protection scope of the present invention, and these will not affect the implementation effect of the present invention and the practicality of the patent. The protection scope required by this application should be subject to the content of its claims, and the specific implementation manners described in the specification can be used to interpret the content of the claims.

Claims

1. A Chinese patent medicine external application plaster for treating neck, shoulder, waist and leg pain, characterized in that, It is made from the following raw materials in parts by weight: 20 - 25 parts of Sarcandra glabra leaves, 12 - 16 parts of Sarcandra glabra roots, 10 - 15 parts of Helwingia himalaica, 10 - 15 parts of Helwingia japonica, 10 - 15 parts of Paris vietnamensis, 10 - 15 parts of Bletilla striata, 10 - 15 parts of Olibanum, 10 - 15 parts of Myrrha, 10 - 15 parts of Rheum officinale, 12 - 16 parts of Phellodendron amurense var. sutchuenense, 10 - 15 parts of Trichosanthes kirilowii Maxim., 6 - 12 parts of Angelica dahurica, 10 - 15 parts of Scutellaria baicalensis, 6 - 12 parts of Ilex purpurea Hassk., 3 - 9 parts of Glycyrrhiza uralensis Fisch., 6 - 10 parts of Aconitum carmichaelii Debx., 9 - 12 parts of Aconitum kusnezoffii Reichb.

2. The Chinese patent medicine external application plaster for treating neck, shoulder, waist and leg pain according to claim 1, wherein It is made from the following raw materials in parts by weight: 21 parts of Sarcandra glabra leaves, 15 parts of Sarcandra glabra roots, 12 parts of Helwingia himalaica, 12 parts of Helwingia japonica, 12 parts of Paris vietnamensis, 12 parts of Bletilla striata, 12 parts of Olibanum, 12 parts of Myrrha, 12 parts of Rheum officinale, 15 parts of Phellodendron amurense var. sutchuenense, 15 parts of Trichosanthes kirilowii Maxim., 9 parts of Angelica dahurica, 12 parts of Scutellaria baicalensis, 9 parts of Ilex purpurea Hassk., 6 parts of Glycyrrhiza uralensis Fisch., 9 parts of Aconitum carmichaelii Debx., 12 parts of Aconitum kusnezoffii Reichb.

3. The preparation method of a Chinese patent medicine external application plaster for treating neck, shoulder, waist and leg pain according to claim 1, characterized in that It includes the following steps: S1. Weigh Sarcandra glabra leaves, Sarcandra glabra roots, Helwingia himalaica, Helwingia japonica, Paris vietnamensis, Bletilla striata, Olibanum, Myrrha, Rheum officinale, Phellodendron amurense var. sutchuenense, Trichosanthes kirilowii Maxim., Angelica dahurica, Scutellaria baicalensis, Ilex purpurea Hassk., Glycyrrhiza uralensis Fisch., Aconitum carmichaelii Debx., and Aconitum kusnezoffii Reichb., grind them into extremely fine powder, and mix them evenly. S2. Add yellow rice wine and stir evenly to form a viscous state for easy application to the affected area.