32results about How to "Long exposure" patented technology

Antibody binding assays and radiolabeling kits are disclosed for radiolabeling and testing therapeutic antibodies in the commercial setting. In particular, the kits are designed for making and evaluating radiolabeled anti-CD20 conjugates to be used for the treatment and imaging of B cell lymphoma tumors. All kit reagents are sterile and are designed to achieve a high level of antibody radiolabeling and product stability with results which are highly reproducible.

The present disclosure provides an apparatus and a method for generating a wide dynamic range image by executing a pixel value combination process of a plurality of different exposure time setting pixels. Control of a different exposure time is performed for each of a plurality of pixels of the same colors configuring a pixel block and an addition pixel value obtained by adding outputs of the plurality of pixels of the same colors of the pixel block is generated. The generation of the addition pixel value is executed in an operation unit having an adding unit that that adds the outputs of the plurality of pixels of the same colors of the pixel block. Or, the generation of the addition pixel value is executed by a floating diffusion (FD) set in a pixel block unit and a charge output from each of the plurality of pixels of the same colors configuring the pixel block is accumulated and output in the floating diffusion (FD).

An imaging apparatus, includes: an imaging optical system; an image pickup device; and a control device which is configured to control the image pickup device, wherein the control device is configured to preliminarily decide an exposure order of a relatively short time exposure in a prescribed image size; an exposure with almost the same exposure time as the relatively short time in a smaller image size than the prescribed image size, and a relatively long time exposure in the prescribed image size, and to perform an imaging operation once by exposing the image pickup device by the decided exposure order.

In one aspect, the invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention further relates to anti-IgE therapeutic molecules.In one aspect, the present invention relates to a method wherein an immunoglobulin single variable domain (such as a Nanobody) and / or construct thereof are absorbed in pulmonary tissue. More particularly, the invention provides systemic delivery of an immunoglobulin single variable domain and / or construct thereof via the pulmonary route.

A method for upgrading a petroleum feedstock using a supercritical water petroleum upgrading system includes introducing the petroleum feedstock, water and an auxiliary feedstock. The method includes operating the system to combine the petroleum feedstock and the water to form a mixed petroleum feedstock and introducing separately and simultaneously into a lower portion of an upflowing supercritical water reactor. The auxiliary feedstock is introduced such that a portion of a fluid contained within the upflowing reactor located proximate to the bottom does not lack fluid momentum. An embodiment of the method includes operating the supercritical water petroleum upgrading system such that the upflowing reactor product fluid is introduced into an upper portion of a downflowing supercritical water reactor. The supercritical water petroleum upgrading system includes the upflowing supercritical water reactor and optionally a downflowing supercritical water reactor.

A protective coating for use on a silicon-containing substrate, and deposition methods therefor. The coating has a barium-strontium-aluminosilicate (BSAS) composition that is less susceptible to degradation by volatilization and in corrosive environments as a result of having at least an outer surface region that consists essentially of one or more stoichiometric crystalline phases of BSAS and is substantially free of a nonstoichiometric second crystalline phase of BSAS that contains a substoichiometric amount of silica. The coating can be produced by carrying out deposition and heat treatment steps that result in the entire coating or just the outer surface region of the coating consisting essentially of the stoichiometric celsian phase.

The present invention relates to a method wherein an immunoglobulin single variable domain (such as a Nanobody) and / or construct thereof are absorbed in pulmonary tissue. More particularly, the invention provides systemic delivery of an immunoglobulin single variable domain and / or construct thereof via the pulmonary route.

A ultra-violet sponge holder that emits sufficient radiation to eradicate germs, bacteria, viruses and other pathogens and microorganisms on a kitchen sponge with a ultra-violet light located on a holder top which is powered by a rechargeable battery with a on / off / auto switch with a safety mechanism whereby only turning the ultra-violet light on when the holder top is closed, also the holder top contains a holder top window whereby allowing the ultra-violet sponge holder to be mobile and a holder bottom contains a sponge holder and a drainage retention area where liquid from sponge is collected.

Apparatus and method for generating a wide dynamic range image by executing a pixel value combination process of a plurality of different exposure time setting pixels. Control of a different exposure time is performed for each of a plurality of pixels of the same colors configuring a pixel block and an addition pixel value obtained by adding outputs of the plurality of pixels of the same colors of the pixel block is generated. The generation of the addition pixel value is executed by an adding unit that adds the outputs of the plurality of pixels of the same colors of the pixel block. Or, the generation of the addition pixel value is executed by a floating diffusion set in a pixel block unit and a charge output from each of the plurality of pixels of the same colors configuring the pixel block is accumulated and output in the floating diffusion.

An improved method and apparatus for high-volume production of coated stents with highly uniform stent coatings using a roll coating technique is provided. In a first embodiment, uncoated stents are placed onto rotating stent holders with automated stent handling equipment. The holders are mounted on an endless conveyer belt which advances the stents toward a stent coater. As the stents advance through the coater, the holders rotate, thereby rolling the stents about their longitudinal axes as coating material is sprayed toward them, ensuring the stents are uniformly coated on their exterior and interior surfaces. After the conveyer turns to carry the coated stents back toward the loading area, the rotating stents pass again through the coating spray, downstream of the initial coating location, thereby increasing the efficient utilization of the coating material. The conveyer then advances the coated stents to an unloading area for removal before the holders return to the stent loading area to receive new stents.

An active pixel sensor cell including at least one photodiode and reset circuitry and an integrating varactor coupled to the photodiode, a method for reading out such a cell, and an image sensor including an array of such cells. The photodiode can be exposed to photons during an exposure interval to accumulate a sequence of subexposure charges at a first node of the photodiode. Each of the subexposure charges accumulates at the first node during a different subexposure interval of the exposure interval. The photodiode is reset during each of a sequence of reset intervals, each reset interval occurring before a different one of the subexposure intervals. An output signal indicative of an exposure charge accumulated at the storage node during the exposure interval can be asserted from the cell, where the exposure charge is indicative of a sum of all the subexposure charges.

The present invention relates to the use of a C1 inhibitor (C1INH) with shorter half-life than plasma-derived C1INH for the preparation of a medicament for the transient treatment of an individual. It relates to both therapeutic and prophylactic treatment. The method of the invention allows for the administration of C1INH at certain therapeutic levels for a concise pre-determined time span. Pharmaceutical compositions based on C1INH with shorter half-lives may be used both in situations where transient treatment is merely and advantage. The advantage of the use according to the invention is that an individual is not exposed to C1INH for longer than required, since the levels of the C1INH more rapidly subsides after administration has stopped. In contrast, levels of plasma-derived C1INH would remain elevated for a prolonged period of time.

The present invention relates to a universal colorant composition that is essentially free of volatile organic compounds (VOCs) and alkyl phenol ethoxylates (APEs). The present invention comprises a dispersing vehicle that comprises a low molecular weight carbamide compound, a C3-C5 polyalcohol, a polyethylene glycol, and optionally water. The dispersing vehicle provides excellent humectant and dispersing properties. The colorant composition comprising the dispersing vehicle maintains its stability and functionality following extended exposure to the atmosphere and / or temperature extremes. The present invention provides a colorant composition that is universally compatible with a wide variety of aqueous / water-based and organic solvent-based paints and coatings, while exhibiting physical and performance characteristics that are comparable to conventional colorant compositions that contain VOCs and APEs. A process for preparing a universal colorant composition for tinting a wide variety of aqueous / water-based and organic solvent-based paints and coatings is also provided.

An active pixel sensor cell including at least one photodiode and reset circuitry and an integrating varactor coupled to the photodiode, a method for reading out such a cell, and an image sensor including an array of such cells. The photodiode can be exposed to photons during an exposure interval to accumulate a sequence of subexposure charges at a first node of the photodiode. Each of the subexposure charges accumulates at the first node during a different subexposure interval of the exposure interval. The photodiode is reset during each of a sequence of reset intervals, each reset interval occurring before a different one of the subexposure intervals. An output signal indicative of an exposure charge accumulated at the storage node during the exposure interval can be asserted from the cell, where the exposure charge is indicative of a sum of all the subexposure charges.

An apparatus for attenuating the intensity of light transmitted through the apparatus is provided. In one embodiment, the apparatus may comprise a first polarizer having a first polarizing orientation and a second polarizer having a polarizing orientation perpendicular to the first polarizer. First and second electrodes are disposed between the polarizers and a nematic liquid crystal layer is disposed between the electrodes. At least one light detector positioned for measuring the intensity of the transmitted light may be positioned on an outer side of the second polarizer. A voltage controller in electrical communication with the light detector is provided for controlling the voltage level applied to the electrodes based on the intensity of the measured light wherein the voltage determines the amount of light transmitted through the apparatus.

The present invention relates to an image-taking apparatus such as a digital camera which is equipped with a release button and shoots a still image when the release button is pressed. It can perform proper metering for still images and reduce a time lag between a half press and the time when it is ready to shoot a still image. The image-taking apparatus has a through image display section which displays a through image which is moving images for display before a half press, a metering section which performs both metering for a through image and metering for a still image before the half press, a distance measuring section which measures distance in response to a half press, and a shooting section which shoots a still image in response to a full press.

A separation device with a gas inlet port that accepts an inlet gas. The inlet gas is composed of a mixture of at least two separable particle components with each component having a different mass. A rotating separation rotor accepts the inlet gas and uses a separator to substantially separate the gas according to mass into two fractions, a heavier and a lighter fraction. One of the fractions is passed to a second separator that further separates that fraction into another two fractions consisting of heavier and lighter fractions. The desired fractions are collected and exhausted from the separation device for use.

Described herein is a novel dosage regimen, and related uses and methods, for a prostaglandin FP receptor agonist (PFPRA) compound topically administered to the skin. The dosage regimen is useful for reduction of subcutaneous fat, for example, in patients who suffer from local excesses of subcutaneous fat. A particular advantage of the dosage regimen is the ability to reduce composition exposure and thereby promote convenience and comfort, while maintaining the desired exposure and therapeutic effect in subcutaneous fat. Further provided are kits according to the novel dosage regimen, comprising a PFPRA composition and instruction for use.

A protective coating for use on a silicon-containing substrate, and deposition methods therefor. The coating has a strontium-aluminosilicate (SAS) composition that is less susceptible to degradation by volatilization and in corrosive environments as a result of having at least an outer surface region that consists essentially of one or more stoichiometric crystalline phases of SAS and is substantially free of a nonstoichiometric second crystalline phase of SAS that contains a substoichiometric amount of silica. The coating can be produced by carrying out deposition and heat treatment steps that result in the entire coating or just the outer surface region of the coating consisting essentially of the stoichiometric celsian phase.

A separation device with a gas inlet port that accepts an inlet gas. The inlet gas is composed of a mixture of at least two separable particle components with each component having a different mass. A rotating separation rotor accepts the inlet gas and uses a separator to substantially separate the gas according to mass into two fractions, a heavier and a lighter fraction. One of the fractions is passed to a second separator that further separates that fraction into another two fractions consisting of heavier and lighter fractions. The desired fractions are collected and exhausted from the separation device for use.

The present invention relates to an indirectly heated gas turbine system comprising a combustion chamber (3) that extends along a central axis of the gas turbine system for the combustion of compressed air and supplied fuel whereby flue gas is formed, a turbine (2) driven by a working medium, a compressor (1) rotatably connected to the turbine for compressing the working medium and / or air to the combustion chamber, and a first heat exchanger device (8) for the transfer of heat between the flue gas and the working medium. The first heat exchanger device and the combustion chamber are integrally formed as a monolithic unit, the first heat exchanger device being substantially arranged within the axial extension of the combustion chamber along the central axis. By the integrated design of the combustion chamber and the first heat exchanger device, a compact, indirectly heated gas turbine system having high efficiency is achieved.

A protective coating for use on a silicon-containing substrate, and deposition methods therefor. The coating has a barium-strontium-aluminosilicate (BSAS) composition that is less susceptible to degradation by volatilization and in corrosive environments as a result of having at least an outer surface region that consists essentially of one or more stoichiometric crystalline phases of BSAS and is substantially free of a nonstoichiometric second crystalline phase of BSAS that contains a substoichiometric amount of silica. The coating can be produced by carrying out deposition and heat treatment steps that result in the entire coating or just the outer surface region of the coating consisting essentially of the stoichiometric celsian phase.

In one aspect, the invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention further relates to anti-IgE therapeutic molecules.In one aspect, the present invention relates to a method wherein an immunoglobulin single variable domain (such as a Nanobody) and / or construct thereof are absorbed in pulmonary tissue. More particularly, the invention provides systemic delivery of an immunoglobulin single variable domain and / or construct thereof via the pulmonary route.

A protective coating for use on a silicon-containing substrate, and deposition methods therefor. The coating has a strontium-aluminosilicate (SAS) composition that is less susceptible to degradation by volatilization and in corrosive environments as a result of having at least an outer surface region that consists essentially of one or more stoichiometric crystalline phases of SAS and is substantially free of a nonstoichiometric second crystalline phase of SAS that contains a substoichiometric amount of silica. The coating can be produced by carrying out deposition and heat treatment steps that result in the entire coating or just the outer surface region of the coating consisting essentially of the stoichiometric celsian phase.

An imaging apparatus, includes: an imaging optical system; an image pickup device; and a control device which is configured to control the image pickup device, wherein the control device is configured to preliminarily decide an exposure order of a relatively short time exposure in a prescribed image size; an exposure with almost the same exposure time as the relatively short time in a smaller image size than the prescribed image size, and a relatively long time exposure in the prescribed image size, and to perform an imaging operation once by exposing the image pickup device by the decided exposure order.