116 results about "Diaminotoluene" patented technology

The invention discloses preparing methods of carbon quantum dots and a phosphorescence composite material of the carbon quantum dots. The carbon quantum dots are synthesized through aniline monomers such as 3,5-diaminobenzoic acid, 2,4-diaminobenzenesulfonic acid and 2,6-diaminotoluene under the room-temperature condition. The composite material is compounded by the water-soluble carbon quantum dots and a hydrophilic poymer such as polyacrylic acid, sodium polyacrylate, polyacrylamide, polymaleic anhydride, polymaleic acid and sodium polystyrenesulfonate. The preparing technology is simple, the raw materials are easy to obtain, the cost is low, and the preparing method is poisonless and environmentally friendly. The carbon quantum dots are diversified, and have the advantages of being highin fluorescence quantum efficiency, good in water solubility and the like; the phosphorescence composite material is diversified, long in phosphorescence service life at the room temperature, and excellent in phosphorescence performance and has a huge application prospect in the fields of counterfeiting prevention, display, biological and chemical detection and the like.

The invention discloses a method for preparing diethyltoluenediamine, which comprises the following steps: diaminotoluene and catalyst are added to a reactor; an 'aromatic amine-aluminum' catalyst system is formed after temperature rising and stirring, and ethylene is pumped into the reactor to purge the hydrogen produced by the reaction; high pressure ethylene gas is pumped in, and after complete alkylation, diphenyl ether or phenoxy biphenyl are added to dilute the reactants; the mixture is filtered, the materials at the bottom of the reactor are recycled, the filtrate is distilled, and diethyltoluenediamine is obtained. The method has the advantages that, aluminum, zinc, aluminum chloride and organic aluminum are used as the catalyst, so activity is increased, reaction pressure is lowered and reaction time is reduced; diphenyl ether or phenoxy biphenyl is added before filtration, so material viscosity can be lowered to facilitate filtration and separation, simultaneously, the 'aromatic amine-aluminum' catalyst system is not damaged; the catalyst can be recycled, so operation steps are reduced, catalyst cost is greatly lowered and environment protection is benefited.

The invention provides a method for economically synthesizing 2,5-diaminotoluene and sulfate of the 2,5-diaminotoluene. The method comprises that: ortoluidine(OT) is subjected to diazonium-coupled reaction under the action of sodium nitrite in inorganic acid water solution to form 2-amino azotoluol(C.I.11160); the 2-amino azotoluol is subjected to reduction hydrogenolysis reaction in the presence of metal or catalyst(Zn or Ni, Pd/C or Raney-Ni), simultaneously the by product of ortoluidine is distilled out by vapor for cyclical utilization, and the 2-amino azotoluol is filtered to synthesize 2,5-diaminotoluene water solution; furthermore, serial products of 2,5-diaminotoluene sulfate(2,5-TDAS) and free 2,5-diaminotoluene(2,5-TDA) of the 2,5-diaminotoluene sulfate are prepared. Due to the adoption of the one-pot in situ synthetic technique, the method has the characteristics of convenient operation, high yield, general equipment, higher recovery circulation rate, easy disposal of waste water, the reduction of waste water discharge by more than 40 percent, effective execution of clean production, generation of circular economy and the like.

The invention relates to a method for synthesizing 2, 6-diaminotoluene. The method comprises the following step: by using 2-chlorine-6-nitrotoluene as a raw material, carrying out reduction reaction and ammonolysis reaction to obtain 2, 6-diaminotoluene. The process is simple in synthesis route, easy to control the reaction and few in three wastes generated at the working segments, thereby meeting the green and environmental friendly requirements; and moreover, produced 2, 6-diaminotoluene is high in purity and excellent in quality, so that the method is an excellent industrial route.

The invention relates to a method for preparing diethyl diaminotoluene. 2, 4- diaminotoluene is in ethylization reaction with ethylizing agent under catalysis of an acidic zeolite molecular sieve to prepare the diethyl diaminotoluene, wherein the ethylizing agent is selected from ethylene and ethanol. The preparation method is completed by one step, simple in process procedure and convenient in operation. The solid acidic catalyst is incorrosive to equipment and easy to be separated from reaction product after reaction is completed, and the method is applicable to continuously operated reactors such as fixed beds and the like and has industrial application prospect. Controlling anhydrous conditions during reaction is not needed, so that reaction conditions are convenient to control and cost of reaction equipment is reduced. By-products such as ethyl products, TDA (tolylenediamine), ethylene or ethanol can be recycled, and accordingly raw materials are effectively saved. Moreover, the method is environment-friendly, high in atom utilization rate, barely free of discharge of waste liquid and waste residue and free of coupled products, thereby being the development orientation of future industrial production.

The invention discloses a preparation method of 2,6-dihydroxytoluene. The preparation method comprises the following steps of: by taking the 2,6-dihydroxytoluene as an initial raw material; and under the effects of a composite tube solid acid catalyst, preparing the 2,6-dihydroxytoluene through high-temperature steam hydrolysis, wherein the liquefied 2,6-dihydroxytoluene and deionized water are fed into a fixed bed reactor according to a flow ratio of (1:1.5)-(1:10), and the mixed materials are subjected to a hydrolysis reaction through the effect of the solid acid catalyst filled in the fixed bed reactor at high temperature. By utilizing the preparation method, liquid acid with large environment pollution is avoided, at the same time, high-temperature equipment and acid corrosion resisting materials are not used, so that the acid corrosion problem of the equipment in the conventional method is overcome, the environment pollution is reduced, and the economic cost is lowered; moreover the process is simple, the product purity and the yield achieve a good level, the purity of the prepared 2,6-dihydroxytoluene is more than 99% under the optimal condition, and the yield can be 95%.

This invention relates to a production method of 5-methyl benzotriazole. Its characteristic is that it includes following steps: (1)in reaction kettle, put 3,4 diaminotoluene in purified water, heat to dissolve; (2)add sodium nitrite of 3,4 diaminotoluene in the solution that is produced by step (1), progress reaction; (3)cool the solution produced by step (2); (4)drop sulphuric acid in the solution produced by step (3), appear a great quantity of crystal; (5)progress manipulation that takes off the liquid for mixture produced by step (4); (6) heat the crystal produced by step (5), dewater; (7)distill the crystal produced by step (6), produce the stated 5-methyl benzotriazole. The production method of this invention uses 3,4 diaminotoluene as raw material, through medium voltage synthesis, acidification, dehydration, distilling manipulation, to prepare 5-methyl benzotriazole. Technology is simple, preparation process is easy to control, yield is high, purity is high, production cost is low, and it is easy to organize industrialized production.

The invention discloses a method for recovering m-diaminotoluene from dinitrotoluene hydrogenated tar. The method adopts the dinitrotoluene hydrogenated tar as the raw material, uses molecular sieves as adsorbent and enables the dinitrotoluene hydrogenated tar and the adsorbent to contact in an adsorption condition, the adsorption temperature is 30-80 DEG C, the desorption temperature is 40-100 DEG C, the residence time is 0.5-8h, and solvent and desorption agent are organic solvent, then residual components in raw material mixture are removed, and the adsorbed m-diaminotoluene is desorbed and recovered by the desorption agent which contains low alcohol in a desorption condition.

A method for separating diaminotoluene through double-effect flow rectification belongs to the rectification process optimization field with better energy conservation and consumption reduction effect. The method comprises the following steps that a coarse TDA material containing water, solvent and tar is dewatered at first; then, the solvent is removed and then the TDA containing tar undergoes isomer separation so as to remove ortho position TDA and meta position TDA; and finally, pure TDA is obtained.

The invention provides water-soluble red/green light double-emission carbon dots (RGDE CDs) which are prepared by taking 2,5-diaminotoluene sulfate as a carbon source through a one-step method. Compared with an existing method, a multi-step material preparation process is avoided. The RGDE CDs prepared by the method have excellent anti-photo-bleaching capability, good biocompatibility and low cytotoxicity. Under the single excitation wavelength, the strength of green fluorescence (with the wavelength of 525nm) of the RGDE CDs is quenched after OONO- is added, and the strength of red fluorescence (with the wavelength of 603nm) is basically not changed. On the basis, the invention establishes a novel method for determining fluorescence of the OONO- through a ratio method.

The invention discloses a method for preparing corresponding diaminotoluene through catalytic hydrogenation of 2,4-dinitrotoluene or 2,6-dinitrotoluene or a mixture of the 2,4-dinitrotoluene and the 2,6-dinitrotoluene. The method for preparing the diaminotoluene through catalytic hydrogenation of the 2,4-dinitrotoluene comprises: respectively adding the 2,4-dinitrotoluene or the 2,6-dinitrotoluene or the mixture of the 2,4-dinitrotoluene and the 2,6-dinitrotoluene, and ethanol and a supported catalyst into a reaction kettle first; performing hydrogenation reaction for 3 to 8 hours at a temperature of between 60 and 90 DEG C, wherein the pressure of the hydrogenation reaction is between 1.5 and 3.0 MPa; and performing solid-liquid separation after the reaction is over, using separated supernatant for product separation, and conveying a separated solid catalyst back to a reaction system for continuous use.

The invention relates to a method for preparing AS-605240 and an application thereof on medicines for treating inflammatory diseases. An improvement of the preparation method disclosed to the international patent is supplied to 5-quinoxaline methylene-2, 4-thiazolidinedione (AS-605240 with a structural formula I). 3, 4-diaminotoluene and glyoxal water solution as raw materials are relatively easy to obtain, reactive reagent, such as sodium bicarbonate, N-bromosuccinimide, carbon tetrachloride, and the like in each step is cheap and easy, and the reaction condition is mild. A great deal of mouse experimental curative effect observation of myocarditis, acute and chronic hepatitis, acute colitis and pancreatitis, which is induced by concanavalin A, is performed by the AS-605240, and the favorable curative effects of the AS-605240 are all confirmed. The prior TZDs, such as troglitazone, and the like are mainly used for aspects on treating diabetes mellitus, angiocardiopathy, and the like. In recent years, a study confirms that the AS-605240 protects the mouse joint and treats rheumatoid arthritis through restraining an osphatidylinositol 3 (PI3K) kinase gamma subtype signal way, therefore, the AS-605240 application on medicines for treating the inflammatory diseases opens up a new medical treatment field on the discovery of thiazolidinedione compound.

The invention relates to a preparation method of 5-amino-6-methyl benzimidazolone, belonging to the technical field of a compound preparation method, in particular to a preparation method of fine chemical intermediate. The preparation method is characterized by sequentially comprising the following steps of: carrying out condensation on 3, 4-diaminotoluene and urea, and preparing 5-methyl benzimidazolone; carrying out nitration reaction on the 5-methyl benzimidazolone under the condition of dilute nitric acid, and preparing 5-nitro-6-methyl benzimidazolone; and finally, carrying out reduction reaction on the 5-nitro-6-methyl benzimidazolone, and preparing the target compound of 5-amino-6-methyl benzimidazolone. In the reduction process of ferrous powder of the reduction reaction of the preparation method, alcohol-water system is taken as a solvent, and the system has low toxicity. In the process of hydrogenation reduction process, DMF-water system is taken as a solvent, and the solvent can be easily recovered, so that the cost is saved. In the process of hydrogenation reduction process, Nguyen Ni or Pd carbon is taken as a catalyst, so that the catalysis effect is good, the cost is low, and the synthetic route has simple technique.

The invention provides a technology for separating and purifying 2,4-diaminotoluene and 2,6-diaminotoluene by a derivatization crystallization process. The technology adopts TDA as a raw material and comprises the following steps of: performing rectification degumming treatment and dissolving in distilled water; adjusting the pH to 6-6.5, adding sodium chloride and performing a catalysis reaction; crystallizing and separating to obtain a crude product of 2,6-diaminotoluene; performing sectional rectification to obtain a pure product of 2,6-diaminotoluene; adjusting the pH of the mother liquid obtained after separating the 2,6-diaminotoluene to 10-12; adding sodium hydrosulfite and performing a catalysis reaction; crystallizing and separating to obtain a crude product of 2,4-diaminotoluene; performing sectional rectification to obtain a pure product of 2,4-diaminotoluene. According to the technology provided by the invention, a derivatization crystallization process is adopted for separation and purification so that the 2,4-diaminotoluene and 2,6-diaminotoluene in TDA (Toluene Diammonium) are completely separated, the utilization rate of the raw materials is over 99%, and the main content of the product is over 99%.

Heat-resistant polyimide copolymers having the following four components: pyromellitic dianhydride (PMDA), 1,4-diaminodiphenyl ether (DADE), biphenyltetracarboxylic dianhydride (BPDA), and 2,4-diaminotoluene (DAT) are provided. In an embodiment the molar ratio of (BPDA):(DADE):(PMDA):(DAT) is 2:2:m:m, in which m is an integer of 3, 4 or 5.

The invention provides a green synthetic method of 2,5-diaminotoluene shown as the formula (II). The method comprises the following steps: taking 2-methyl-4-nitroaniline as raw material, magnetic Mg/Al-hydrotalcite solid alkali as catalyst and hydrazine hydrate as reducing agent, reacting at the temperature of 0-100 DEG C for 1-20 hours, and separating and purifying the reaction solution to prepare the 2,5-diaminotoluene. Compared with the prior art, the green synthetic method has the beneficial effects that: the magnetic Mg/Al-hydrotalcite solid alkali taken as catalyst and the hydrazine hydrate taken as reducing agent are applied in the synthesis of the 2,5-diaminotoluene, so that compared with the prior art, the preparation of the 2,5-diaminotoluene is simpler in processing, easy in operation, high in reaction yield, and good in product purity, has no pollution to environment, is suitable for industrialized production with a certain scale, is a green and clean synthetic line, and has no application report of industrialized production at present.

The invention discloses a technology for purifying 2, 4-diaminotoluene by a recrystallization method. The technology comprises the following steps: a) mixing the mixture of 2,4-diaminotoluene and 2,6-diaminotoluene, distilled water and an organic alcohol solvent or a ketone solvent at the mass ratio of 1:(0.5-1.5):(0.5-1.5) in a reactor, stirring the materials under a regurgitation state at the temperature of 50-90 DEG C to enable the materials to be uniformly mixed; b) stopping heating, cooling the mixed materials to the temperature of 5-25 DEG C in a crystallizer, and separating out crystals; c) performing centrifugation and washing; d) drying the washed crystals so as to obtain the pure product 2,4-diaminotoluene. Through the adoption of the technology disclosed by the invention, the content of the 2,4-diaminotoluene in products exceeds more than 99.5%, the product quality is improved, and the additional value is increased; besides, washed raffinate can be circularly utilized and can be used for replacing about 60% of raw material water and a solvent, so that the production cost is reduced, requirements of energy conservation and emission reduction are met, and secondary pollution is avoided.

The invention provides a 2, 4-diaminotoluene purification system which comprises a crystallizer, a heat exchanger, a raw material tank, a product receiving tank, a sweat liquid receiving tank and a residual liquid receiving tank. The crystallizer is provided with a feed port and a discharge port. The crystallizer further comprises a temperature adjusting sleeve which is arranged around the crystallizer and used for changing temperature of the crystallizer. The temperature adjusting sleeve is provided with a circulating water inlet and a circulating water outlet. The heat exchanger is used for heating or cooling circulating water in the temperature adjusting sleeve. The raw material tank is communicated with the feed port of the crystallizer. The product receiving tank, the sweat liquid receiving tank and the residual liquid receiving tank are communicated with the discharge port of the crystallizer. The purification system can carry out TDA purification conveniently, the structure is compact, and therefore the overall occupied area is small.

The invention relates to an oxidized type dyeing composition. The oxidized type dyeing composition comprises a first agent and a second agent, wherein the first agent contains an oxidation coloring base, a coupling agent and an oxidation retarder; the second agent contains an oxidant; the oxidation coloring base comprises 2,5-diaminotoluene or an addition salt thereof, the coupling agent comprises hydroxyethyl-3,4-methylene dioxyaniline or an addition salt thereof, and the oxidation retarder is a polyhydroxyl phenol oxidation retarder. The oxidized type dyeing composition provided by the invention is applied to hair, of which the ratio of white hair does not exceed 50%, and the color difference between the white hair and black hair after hair dyeing can be reduced while the white hair is excellently covered, so that the dyeing requirement that the hair is uniformly dyed to brown can be met.

The invention discloses a 2,4-diaminotoluene molecularly imprinted polymer, a preparation method and application thereof, and particularly provides the 2,4-diaminotoluene molecularly imprinted polymer prepared from a functional monomer of methyl acrylic acid, a template molecule 2,4-diaminotoluene, and a crosslinking agent divinyl benzene, a preparation method for the molecularly imprinted polymer, and application of the molecularly imprinted polymer to solid phase extraction separation. The 2,4-diaminotoluene molecularly imprinted polymer provided by the invention is more excellent in mechanical property, higher in specific volume, higher in adsorption acting force to 2,4-diaminotoluene, and higher in adsorption capacity to 2,4-diaminotoluene; the preparation method for the 2,4-diaminotoluene molecularly imprinted polymer is short in synthesis time, and the washing of the template molecule is easy; the molecularly imprinted polymer is high in solid phase extraction efficiency to 2,4-diaminotoluene and more thorough in adsorption.