208 results about "Perfluoroacetic Acid" patented technology

The invention relates to the technical field of organic synthesis, and discloses a preparation method of bromo-pyrrole nitrile. The method comprises the following steps: (1) mixing p-chlorophenylglycine, acetonitrile, trifluoroacetic acid and a catalyst, then dropwise adding acyl chloride and carrying out acylation reaction, and after the reaction is completed, purging with an inert gas; (2) under the inert gas, mixing the mixture obtained in the step (1) with inorganic salt, then dropwise adding 2-chloroacrylonitrile, carrying out cyclization reaction, and separating a liquid phase from the obtained mixture; and (3) under the inert gas, mixing the liquid phase obtained in the step (2), hydrobromic acid and hydrogen peroxide, carrying out a bromination reaction, then extracting with acetonitrile to obtain an acetonitrile layer, then removing the acetonitrile, and then carrying out cooling crystallization to obtain the bromo-pyrrolenitrile. According to the technical scheme, the reaction yield is high, different solvents do not need to be frequently replaced, and the solvents can be recycled.

The invention discloses an antibacterial peptide simulant based on adamantane modification and application of the antibacterial peptide simulant. The preparation method comprises the following steps: performing amide condensation on Fmoc amino acid to obtain a compound of which the carboxyl terminal is modified by amantadine or Boc protected aliphatic amine, and then removing an Fmoc group by piperidine to obtain a series of amantadine modified crude products and Boc protected aliphatic amine modified intermediate compounds; the intermediate compound is subjected to amide condensation to obtain a compound of which the amino terminal is further modified by adamantanic acid, then other protecting groups are cracked by trifluoroacetic acid to obtain a series of adamantanic acid modified crude products, and the crude products are purified to obtain the adamantane modified peptidomimetic. The adamantane modified peptidomimetic is used for preparing drugs for treating infectious diseases caused by sensitive bacteria and drug-resistant bacteria, has efficient antibacterial activity and low toxicity, and is not influenced by a traditional drug-resistant mechanism.

The invention relates to a pyrimidyl full-conjugated structure covalent organic framework material, a catalyst containing the pyrimidyl full-conjugated structure covalent organic framework material and a preparation method and application thereof. The preparation method of the pyrimidyl full-conjugated structure covalent organic framework material comprises the following steps: (1) dissolving an aldehyde precursor and a methyl precursor containing a bipyrimidine structure in an organic mixed solvent, fully dispersing, and adding a catalyst to obtain a mixed solution; the organic mixed solvent is composed of mesitylene, 1, 4-dioxane and acetonitrile, and the catalyst is trifluoroacetic acid; (2) sequentially carrying out liquid nitrogen freezing-vacuumizing-unfreezing cyclic operation, vacuum sealing and secondary unfreezing on the obtained mixed solution to room temperature, and reacting at the temperature of 120-150 DEG C to obtain a crude product; and (3) deblocking the reaction system of the obtained crude product, and then carrying out solid-liquid separation, washing, Soxhlet extraction and drying to obtain the pyrimidyl covalent organic framework material with the fully conjugated structure.

The invention provides chlorotrifluoroethylene continuously prepared based on a microchannel reactor and a preparation method of the chlorotrifluoroethylene, and the chlorotrifluoroethylene comprises the following raw materials in parts by weight: 1, 1, 2-trifluoro-1, 2, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3 The low-temperature refrigerant refrigerant is prepared from the following components in parts by weight: 90 to 100 parts of 1, 2-trichloroethane, 1 to 5 parts of a zinc fluoride induced palladium-copper bimetallic catalyst, 8 to 15 parts of a cyclohexyl dimethyl ether-formic acid composite hydrogen donor, 0.5 to 2 parts of trifluoroacetic anhydride, 0.1 to 0.5 part of a perfluoropolyether lubricant, a proper amount of a low-temperature mixed refrigerant and 15 to 20 percent by weight of diluted hydrochloric acid. According to the invention, the preparation efficiency and product purity of chlorotrifluoroethylene can be improved, and stable operation of the preparation system and reasonable treatment of byproducts can be guaranteed.

The invention provides a preparation method of an efficient selective antagonist BQ-788, and relates to the technical field of preparation of antagonists. A solid-liquid combination method is adopted for synthesis, due to the fact that dimethyl dialkanoate on a side chain of tryptophan (DTrp) is difficult, Fmoc-DTrp (CO2Me)-OH is obtained through liquid-phase synthesis, p-methoxybenzyl is selected for protecting carboxyl in the synthesis process, the carboxyl can be removed through trifluoroacetic acid subsequently, and the risk that an indole ring of tryptophan is reduced due to hydrogenation can be successfully avoided. According to the present invention, by using the solid phase synthesis method, the fragment can be rapidly and efficiently obtained, the racemization problem during the condensation process can be effectively avoided, the urea is formed on the solid phase, the operation is simple and convenient, the hydrogen and the diphosgene are not used during the preparation process, the production is safe, the obtained product has characteristics of high yield and high purity, and the preparation steps are less.

An electrolyte solution for a lithium secondary battery is provided, comprising a lithium salt, a nonaqueous organic solvent with at least 50% FSA by volume, and a silver (Ag) compound additive selected from AgHFB, AgPFP, or silver trifluoroacetate. The additive is present in an amount of about 0.05 wt % to 0.2 wt % to promote stable SEI layer formation and reduce lithium deposition overvoltage. The solution may also include a secondary additive such as calcium hydride (CaH2) or magnesium fluoride (MgF2) to further suppress lithium dendrite growth. The lithium secondary battery incorporating this electrolyte is designed to form a lithium metal layer with a thickness of 40 to 45 μm and a surface pore average diameter of less than 1 μm during the initial charging process, optimizing performance and stability.

The invention belongs to the technical field of chromatographic separation materials, and discloses a preparation method and application of a GM-8 nanosheet material. The preparation method of the material comprises the following steps: respectively dissolving Cu (NO3) 2.3 H2O and 1, 3, 6, 8-tetra (4-carboxybenzene) pyrene in an organic solvent, mixing, transferring into a reaction bottle, adding trifluoroacetic acid and pyridine, and uniformly mixing and stirring to obtain a reaction mixture; and heating the reaction mixture to react for 7-9 hours to obtain a blue precipitate, cooling the blue precipitate to room temperature, and washing and drying the blue precipitate to obtain the ultra-stable microporous GM-8 nanosheet material. The nanosheet GM-8 is used as a gas chromatography stationary phase, high-efficiency separation and trace detection of xylene isomers can be realized, and the chromatographic column still keeps excellent separation capacity after being stored in an environment with air humidity of 65-90% for 31 months. The capillary gas chromatographic column can realize high-efficiency separation of disubstituted benzene isomers such as xylene, the separation degree of m-xylene / p-xylene is up to 18.2, and a new solution is provided for high-efficiency separation of isomers with similar properties.

The invention provides a green and efficient production method of hexafluoropropylene oxide, and belongs to the technical field of synthesis of organic fluorine compounds. The method comprises the following steps: carrying out a continuous oxidation reaction on hexafluoropropylene, oxygen and a perfluoro solvent in an immersed supergravity reactor to generate HFPO and byproducts carbonyl fluoride and trifluoroacetyl fluoride, removing the solvent from the reacted liquid, feeding the liquid into an acyl fluoride rectifying tower, separating low-boiling-point acyl fluoride from the tower top, enriching HFPO, unreacted HFP and a small amount of acyl fluoride from the tower bottom, and carrying out a continuous oxidation reaction on the HFPO and the byproducts carbonyl fluoride and trifluoroacetyl fluoride. Converting acyl fluoride into anhydrous trifluoroacetic acid from a high-boiling-point substance at the bottom of the tower through a hydrolysis tower, carrying out alkali washing on the synthesis gas to obtain an HFPO crude product, and further carrying out drying and extractive distillation to obtain an HFPO product; acyl fluoride rectified by an acyl fluoride rectifying tower is directly used for producing PAVE, and long-chain perfluoroacyl fluoride accumulated in a solvent of oxidation reaction is hydrolyzed to synthesize a non-PFOA emulsifier. The method has the advantages of high HFPO selectivity, short reaction time and high safety; the method realizes resource comprehensive utilization of byproducts, and is environment-friendly and economical.

The invention belongs to the technical field of medical nano-materials, and particularly relates to a preparation method of a nano-metal covalent organic framework material for enhancing cell ferroptosis by consuming glutathione as well as an obtained product and application of the nano-metal covalent organic framework material. The material is prepared by the following steps: firstly, preparing a metal organic ligand Cu3-PyCA3; the preparation method comprises the following steps: firstly, preparing a metal organic ligand Cu3-PyCA3, then mixing the metal organic ligand Cu3-PyCA3, 2, 5-diethoxybenzene-1, 4-bis (formylhydrazine), mesitylene, 1, 4-dioxane and a trifluoroacetic acid solution, and then reacting to obtain a nano metal covalent organic framework Cu3-MCOF; and finally, uniformly mixing the activated hyaluronic acid solution and the Cu3-MCOF, and intensely stirring to obtain the Cu3-MCOF-coated HA. The nano-metal covalent organic framework provided by the invention can consume glutathione to enhance cell ferroptosis, and the nano-metal covalent organic framework Cu3-MCOF can quickly react with glutathione, so that the framework structure of the Cu3-MCOF is seriously damaged, the crystalline state disappears, a large number of ribbons are further assembled and generated, glutathione is consumed, and the ferroptosis of cells is enhanced. The ferroptosis tumor treatment enhancer has an application prospect.

The invention relates to a chlorophyll derivative-based efficient nickel oxide-based perovskite solar cell, and belongs to the technical field of perovskite solar cells. The perovskite solar cell sequentially comprises a transparent conductive glass anode, a hole transport layer, a chlorophyll derivative passivation layer, a perovskite layer, an electron transport layer, a hole barrier layer and a metal cathode from bottom to top, the hole transport layer is nickel oxide; and the chlorophyll derivative passivation layer is a chlorophyll derivative layer containing trifluoroacetate. The perovskite solar cell is an efficient nickel oxide-based perovskite solar cell with chlorophyll derivatives containing trifluoroacetate as a hole transport layer and a perovskite layer interface passivation layer, and the photoelectric conversion efficiency of the perovskite solar cell can reach 25.54%. According to the preparation method of the perovskite solar cell, the synthesis process is simple and easy to implement, the requirement for equipment is low, and the preparation method has a good industrial application prospect.

The invention discloses a method for preparing a perovskite solar cell based on a fused salt doped Spiro-OMeTAD hole transport layer, and the method comprises the steps: dissolving lead iodide and formamidine iodide in a mixed solvent of N, N-dimethylformamide and dimethyl sulfoxide according to a molar ratio of (0.8-1.5): 1 to prepare an FAPbI3 perovskite precursor solution; the method comprises the following steps: mixing cyclohexylamine trifluoroacetic acid and 4-tert-butylpyridine according to a molar ratio of 1: (8-14), dissolving the mixture in a 70-110 mg / mL Spiro-OMeTAD chlorobenzene solution, adding an acetonitrile solution of LiTFSi, and stirring at normal temperature to obtain a hole transport material Spiro-OMeTAD solution; spin-coating the FTO substrate with an electron transport layer material, spin-coating the electron transport layer with the FAPbI3 perovskite precursor solution, and annealing to form a perovskite thin film; the method comprises the following steps: spin-coating an ammonium butyrate iodide solution on a perovskite thin film to obtain an interface modification layer, spin-coating a hole transport material Spiro-OMeTAD solution on the interface modification layer to obtain a cyclohexylamine trifluoroacetic acid doped Spiro-OMeTAD hole transport layer, and evaporating an interface modification layer and a metal electrode on the Spiro-OMeTAD hole transport layer.

The invention discloses a sodium ion battery electrolyte as well as a preparation method and application thereof, and belongs to the technical field of sodium ions. The sodium ion battery electrolyte provided by the invention comprises a sodium salt, an organic solvent, a main additive and an auxiliary additive, the main additive is one or more of sodium difluorophosphate NaDFP, sodium tetrafluoroborate NaBF4, sodium trifluoroacetate NaTFA or sodium nitrate NaNO3, and the auxiliary additive is one or more of sodium difluorophosphate NaDFP, sodium tetrafluoroborate NaBF4, sodium trifluoroacetate NaTFA or sodium nitrate NaNO3. According to the present invention, one or more of tris (trimethylsilane) borate TMSB, tris (trimethylsilane) phosphate TMSP, (pentafluorophenyl) silane TPFS or tris (trimethylsilane) phosphite TMSPi are adopted, the circulation capacity retention rate in a wide temperature range is significantly improved through the synergistic mechanism in a certain proportion range, the capacity retention rate is high at a high rate of 10 C and above, the rapid charging performance is provided, and the application prospect is broad. The cost is reduced; and commercialization is promoted.

The invention provides a preparation method of an environment-friendly two-dimensional high-strength coating and a raw material recycling method, and the preparation method comprises the following steps: preparing trimesic acid, melamine, a solution A and a solution B into a reaction solution according to a proportion in a glove box, and putting the reaction solution into a high-pressure reaction kettle to react to form gel; and mixing the gel with ethanol, carrying out ultrasonic treatment, filtering, washing and drying to obtain faint yellow polymer powder, dissolving the powder in trifluoroacetic acid, and preparing film coatings with different thicknesses by adjusting the concentration of the solution. According to the raw material recovery method of the coating, an acid catalyst is used for hydrolysis, trimesic acid and melamine are recovered, and the recovery rate reaches 88.9% or above. The prepared coating material has the advantages of high strength, low density, excellent leakproofness and chemical corrosion resistance, raw material recycling is realized, the production cost is reduced, the green and environment-friendly requirements are met, and the coating material is suitable for light high-strength materials, protective coatings and other high-performance application fields.

The application provides a method for synchronously separating active substances of Haematococcus pluvialis, and relates to the technical field of natural product extraction, and comprises an extraction phase with a mass ratio of 20%-50%, and the balance is water; the extraction phase is a quaternary phosphonium ionic liquid or a eutectic solvent; the quaternary phosphonium ionic liquid comprises tetrabutylphosphonium trifluoroacetate or tributyl octyl phosphonium bromide; and the eutectic solvent comprises a quaternary phosphonium ionic liquid and a fatty acid with a molar ratio of 1:1-5:3. The extraction phase has weak acidity, the ability to form van der Waals forces and hydrogen bond interactions, the Haematococcus pluvialis cell wall breaking effect and high solubility. The extraction phase can form liquid-liquid phase separation, can realize the synchronous extraction of Haematococcus pluvialis cell wall breaking, astaxanthin, carbohydrates and proteins, and has no organic solvent, is simple to operate, has short extraction time and high extraction efficiency. The method solves the technical problem that the extraction agent in the prior art cannot effectively separate multiple active substances of Haematococcus pluvialis.

The invention relates to a zwitterionic particle and a preparation method and application thereof, the zwitterionic particle is of a core-shell structure, the shell is a water-soluble zwitterionic polymer, and the core is a water-insoluble cross-linked polymer; the preparation method comprises the following steps: firstly, preparing core-shell polymer particles of which shells are polydiolefin and cores are crosslinked polystyrene or crosslinked polymethacrylate polymers by combining an active anionic polymerization mediated polymerization induced self-assembly technology with a post-polymerization modification technology; then, polydiolefin of a shell layer is hydrolyzed with trifluoroacetic acid, hydroxylated polydiolefin is prepared, hydroxyl is converted into potassium alkoxide, bromoisobutyl ester or a chain transfer reagent, and allyl monomers containing tertiary amine are initiated to be subjected to controllable / active polymerization; and finally, converting the tertiary amine group into a zwitterionic group by using a modification reagent to prepare the core-shell particle of which the shell is a water-soluble zwitterionic polymer and the core is a water-insoluble polymer. According to the invention, the problem of limitation in the aspects of controllability, function expansion and the like in the prior art is solved.

The invention relates to a core-shell polyacrylamide nano flocculant as well as a preparation method and application thereof, the flocculant is of a core-shell structure, the shell is a water-soluble polyacrylamide polymer, and the core is cross-linked poly (p-hydroxystyrene); the preparation method comprises the following steps: preparing a poly (p-tert-butoxystyrene-b-polyacrylate) block polymer or a poly (4-acetoxystyrene-b-polyacrylate) block polymer; carrying out hydrolysis and self-assembly on poly (p-tert-butoxystyrene) or poly (4-acetoxystyrene) on the block polymer at the same time in the presence of a trifluoroacetic acid hydrolysis reagent by utilizing a modification induced self-assembly process, and carrying out in-situ crosslinking on poly (p-hydroxystyrene) obtained by hydrolysis by using formaldehyde; and in the presence of a 1, 5, 7-triazabicyclo [4.4. 0] decene-5-ene catalyst, modifying the polyacrylate block by using an amination reagent to prepare the flocculant. Compared with the prior art, the flocculant provided by the invention has the advantages of controllable morphology, stable cross-linkable property and the like.

The present invention discloses a medium and low temperature shape memory polyurethane flexible conductive elastomer and a preparation method thereof. First, a polyurethane prepolymer is formed by a bis-NCO-functionalized ureidopyrimidinone (UPy) derivative (UPy-2NCO) and an -OH-terminated flexible chain molecule, and then reacted with a diamine to obtain a polyurethane elastomer. Subsequently, using the polyurethane elastomer as a substrate, silver nanoparticles are directly deposited onto the polyurethane elastomer film by hydrazine hydrate reduction of silver trifluoroacetate to prepare a high tensile strength and medium and low temperature shape memory function polyurethane-based composite flexible conductive elastomer. Compared with the prior art, the flexible conductive elastomer has ultra-high tensile strength and deformation behavior, excellent electrical conductivity, good shape memory behavior, outstanding medium and low temperature resistance performance, stable sensing performance and good electrical conductivity repair performance, and can be used as a flexible sensor and a temperature control element, and can be applied to fields such as electronic circuits and aerospace.

The present invention discloses a method for improving the stability of solid-phase synthesized multi-cysteine ​​polypeptides, primarily addressing the technical problem of poor stability caused by the susceptibility of such polypeptides to oxidation, degradation, elimination, denaturation, and inactivation. The method comprises the following steps: 1) purifying the multi-cysteine ​​polypeptide synthesized by solid-phase synthesis via liquid chromatography to obtain a preparation solution containing trifluoroacetate; 2) passing the preparation solution through a depth filter containing hydrophilic silica aerogel spheres as a filter material to remove metal ions and trace peroxides contained in the preparation solution by adsorption; 3) further passing the preparation solution through a weakly basic cation exchange resin to a pH of 6.3-6.5; 4) removing the sodium trifluoroacetate in the preparation solution by tangential flow filtration with low pressure, obtaining a weakly acidic, salt-free preparation solution; 5) freezing and vacuum drying to obtain a solid powder final product; 6) vacuum packaging and frozen storage; and 7) ensuring purity and stability after storage in accordance with scientific research requirements.

The utility model discloses a sodium trifluoroacetate purification device, which relates to the technical field of purification, and comprises a workbench, a crystallization chamber, a drying chamber, a stirring assembly and a water cooling assembly, the crystallization chamber is installed on the top surface of the workbench, and two sides of the workbench are fixedly connected with a pair of first installation blocks; an elastic component is fixedly connected to the bottom surface of the first mounting block, and a second mounting block is fixedly connected to the end, away from the first mounting block, of the elastic component; according to the utility model, the output motor drives the stirring rod and the connecting plate to rotate, so that internal compounds are quickly and uniformly mixed and stirred, and meanwhile, the driving motor is combined to drive the rocker to rotate, so that the drying chamber vibrates through the transmission mechanism, and the combination of vibration and stirring not only promotes the uniform mixing of the compounds, but also improves the drying efficiency. And evaporation of water in the drying process is accelerated through gaps generated by vibration, and the drying efficiency and the purification effect are improved.

The invention discloses a preparation method of a three-dimensional perovskite blue light film in an air environment. The preparation method comprises the following steps: S1, preparing a substrate modified by polyvinylpyrrolidone; s2, preparing a precursor solution of the three-dimensional perovskite blue light thin film; and S3, heating the precursor solution prepared in S2, and forming a film on a substrate modified by polyvinylpyrrolidone to prepare the three-dimensional perovskite blue light thin film. The preparation method comprises the following steps: modifying a substrate by polyvinylpyrrolidone and a precursor solution consisting of dimethyl sulfoxide containing cesium trifluoroacetate, lead bromide, rubidium chloride, triphenylphosphine oxide, 18-crown ether-6 and cesium bromide in different proportions, and combining a solvent treatment process in a spin coating process of the heated precursor solution and the spin coating process of the solution; and a series of perovskite blue light films are prepared in an air environment. The method provides a new reference for large-scale application of the perovskite light-emitting layer, especially the perovskite blue light-emitting layer, in light-emitting films and devices.

The invention discloses a preparation method and application of a silicon-based functionalized fluorenyl polysubstituted acetylene copolymer and a gas separation membrane thereof. Belongs to the technical field of polymer material and gas separation. The invention provides a new thought for preparation of a high-permeability gas separation membrane material. The preparation method comprises the following steps: carrying out copolymerization on 1-phenyl-2-(7-trimethylsilyl-9, 9-bis (trimethylsilyl-fluorene-2-yl) acetylene and 1-phenyl-2-(7-trimethylsilyl-9, 9-dimethyl-fluorene-2-yl) acetylene under the catalysis of TaCl5-n-Bu4Sn, so as to prepare a copolymer with high molecular weight; the preparation method comprises the following steps of: carrying out film casting on a solution of the nano-silver oxide, and then carrying out desiliconization treatment by using normal hexane / trifluoroacetic acid to obtain a gas separation membrane with the thickness of 100-220 microns, the specific surface area of 298-492 m / g and the total pore volume of 0.134-0.299 cm / g. The prepared separation membrane has the advantages that the COpermeability is up to 36,900 Barrer, the Opermeability is 19,800 Barrer, the thermal decomposition temperature exceeds 420 DEG C, the separation membrane can be used for separating gases such as COO, ON and the like, the preparation process is simple and convenient, and the industrial potential is realized.

The invention relates to a method for analyzing and detecting a non-azonetin enantiomer, which adopts normal-phase high performance liquid chromatography and takes normal hexane-ethanol-trifluoroacetic acid as a mobile phase to detect the non-azonetin enantiomer, and the specific chromatographic conditions are as follows: a chromatographic column is prepared by covalently bonding amylose-tri (3, 4, 6-trimethyl-1, 3-pentanediol) on the surface of silica gel; 2, 5-dichlorophenyl carbamate is used as a filling agent (IE, 4.6 * 250 mm, 5.0 [mu] m); a mobile phase: n-hexane: ethanol: trifluoroacetic acid = 500: 500: 1 (V / V / V); the flow rate is 1.0 ml / min; the column temperature is 30 DEG C; the sample size is 20 [mu] l; the detection wavelength is 280 nm; the elution gradient is isocratic elution. The invention provides a high performance liquid chromatography method for analyzing the enantiomer of the fiazonetin, the complete separation of the fiazonetin and the enantiomer of the fiazonetin can be realized by adopting the method, and the separation degree of a main component and the enantiomer is greater than 1.5.

The present application relates to a method for synthesizing leu-enkephalin by Fmoc method, which uses Fmoc-protected amino acid as monomer, and sequentially connects amino acid to resin. In the synthesis of leu-enkephalin, all the amino acids do not have any side chain protection group. The Fmoc protection group is removed by using a solution of 1.00 mol / L imidazole and 0.02 mol / L tricyclohexylphosphine in tetrahydrofuran, and finally leu-enkephalin is obtained by removing the resin with aqueous trifluoroacetic acid. The present application first uses imidazole and tricyclohexylphosphine as components of Fmoc deprotection agent, instead of traditional pyridine. The deprotection agent is not controlled by "controlled chemicals", is cheap and easy to obtain, is stable in nature, and is low in toxicity, volatility and corrosion. The deprotection agent has excellent Fmoc removal ability, does not cause phenolic ring acylation side reaction of tyrosine side chain, does not need any side chain protection, simplifies the production process of polypeptide, reduces the preparation cost of polypeptide, and provides great improvement space for the design of synthesis strategy of polypeptide containing basic sensitive side chain protection group.

An object of the present disclosure is to provide a nonaqueous electrolytic solution and a lithium ion secondary battery using same, the nonaqueous electrolytic solution having both excellent battery safety when used at a high temperature, an important feature for secondary batteries to be installed in modern vehicles such as electric vehicles, and having excellent battery characteristics. The nonaqueous electrolytic solution of the present disclosure is a nonaqueous electrolytic solution including an electrolyte salt dissolved in a nonaqueous solvent, the nonaqueous solvent containing from 80 to 100 vol % in total of at least one selected from ethylene carbonate, propylene carbonate, and γ-butyrolactone, and the nonaqueous electrolytic solution further including a trifluoroacetic acid ester having an alcohol group with a carbon chain length of from 6 to 8.

The invention relates to a preparation method of a hyperbranched polymer containing phthalic dicarboxaldehyde, which comprises the following steps: dissolving a chain transfer agent, a monomer ADP containing a phthalic dicarboxaldehyde protecting group, dimethylacrylamide and azodiisobutyronitrile in tetrahydrofuran, and reacting for 8-24 hours at 70 DEG C in an inert atmosphere; cooling to normal temperature, adding trifluoroacetic acid, and continuously reacting for 1-3 hours; and stopping the reaction and precipitating, and then drying in vacuum to obtain the hyperbranched polymer containing o-phthalaldehyde. The hyperbranched polymer prepared by the invention can be efficiently cross-linked and fixed with sclera collagen, and is used for intervention treatment of myopia progress.

The invention relates to a method for detecting related substances of a macloxvir tablet, which belongs to the technical field of pharmaceutical analysis, and adopts a high performance liquid chromatography, a reversed-phase liquid chromatographic column taking octadecyl bonded silica gel as a filler, a mixed solution of a trifluoroacetic acid solution containing ion pairs and acetonitrile as a mobile phase A and acetonitrile as a mobile phase B, a gradient elution mode is adopted. According to the method, elution conditions and detection conditions of high performance liquid chromatography are optimized through scientific screening, effective separation and detection of nine known impurities which are similar in structure and difficult to separate and seven or more unknown impurities contained in the macavir tablets are achieved at the same time, splitting of a detection method is avoided, time cost can be saved, economic benefits are improved, and the method is suitable for industrial production. The method has a positive effect and practical application value on detection of related substances of the macloxvir tablets.

The invention discloses bio-based polyamide with low water absorption and a preparation method thereof, and belongs to the technical field of polyamide preparation. The bio-based polyamide with the low water absorption rate is prepared from the following components in parts by weight: 30 to 50 parts of pentamethylene diamine, 15 to 30 parts of sebacic acid, 5 to 12 parts of citric acid, 5 to 10 parts of hexamethylenediamine, 2 to 5 parts of a hydrophobic auxiliary agent and 1 to 5 parts of a modified high-temperature-resistant additive, the hydrophobic additive is prepared from acetoxybenzoic acid, nonadecanoic acid, m-dimethoxybenzene, trifluoroacetic anhydride and methyl tert-butyl ether as raw materials, and the modified high-temperature-resistant additive is prepared from o-phenylenediamine, chloroacetic acid, vanillin, benzoyl bromide and thiourea as raw materials. The bio-based polyamide prepared from the substances has low water absorption and excellent thermal stability.

The invention discloses a method for microwave digestion of an express packaging material and application, and the method comprises the following steps: S1, crushing and grinding the express packaging material until the particle size is less than 100 [mu] m; s2, adding a composite acid-chitinase mixed solution into the digestion tank, and preliminarily contacting with the sample to weaken the structure of the sample; the composite acid-chitinase mixed solution comprises a composite acid mixed solution and a chitinase aqueous solution; the composite acid mixed solution comprises nitric acid, trifluoroacetic acid, hydrogen peroxide and formic acid; s3, placing the digestion tank treated in the step S2 on a turntable of a microwave digestion instrument, and carrying out pulse type microwave digestion; the microwave time is 25 minutes to 35 minutes; according to the method, pulse type microwaves are matched with the composite acid to digest the express packaging material, the digestion solution with high digestion completeness is obtained, HP-beta-CD and DTPA are used as double ligands to synergistically extract heavy metals such as lead and cadmium, the selectivity is good, and the efficiency is high.

The utility model belongs to the technical field of rectification systems of chemicals, and particularly relates to a continuous rectification system for ethyl trifluoroacetate. The ethyl trifluoroacetate continuous rectification system comprises a first-stage rectification tower and a second-stage rectification tower, the tower top of the first-stage rectification tower is connected with a first-stage condenser, a gas outlet of the first-stage condenser is connected with a first-stage absorption device, a liquid outlet of the first-stage condenser is connected with an alcohol-containing substance receiving tank, and the alcohol-containing substance receiving tank is connected with a second-stage absorption device. The first-stage rectifying tower is connected with the second-stage rectifying tower, the tower top of the second-stage rectifying tower is connected with the second-stage condenser, a gas outlet of the second-stage condenser is connected with the first-stage absorption device, and a liquid outlet of the second-stage condenser is connected with the finished product receiving tank. The ethyl trifluoroacetate continuous rectification system provided by the utility model is easy to operate, the cost is reduced, the yield of rectified products is improved, and the process is environment-friendly.

The present invention provides a stain-resistant and wrinkle-resistant ultrafine polyester fiber fabric and a preparation method thereof. The preparation method comprises the following steps: S1. dissolving polyester chips in a trifluoroacetic acid / dichloromethane solution to obtain solution A; S2. adding a copper nitrate solution to solution A to obtain solution B, electrospinning solution B to obtain polyester / copper nitrate fiber yarn, and then weaving polyester / copper nitrate fabric; S3. immersing the polyester / copper nitrate fabric in a cassia seed extract solution, drying the polyester / copper nitrate fabric, and immersing the polyester / copper nitrate fabric in an alkaline solution to obtain a polyester fabric containing a liquid containing copper; S4. immersing the polyester fabric containing a liquid containing copper in a 3,4-epoxycyclohexyl methacrylate / ethanol solution, performing two dipping and two rolling steps to obtain the stain-resistant and wrinkle-resistant ultrafine polyester fiber fabric. The fabric obtained by the present invention has good stain-resistant and wrinkle-resistant properties.