44 results about "Laboratory scale" patented technology

The invention discloses a granular catalyst and a preparation method thereof, and belongs to the technical field of chemical engineering. The preparation method of the granular catalyst comprises the following steps: S1, mixing raw materials containing a carbon material, an active metal material and a solvent to form slurry; s2, the slurry serves as a cathode in an electrode system and is subjected to pulse electrodeposition treatment, and active metal is deposited on the surface of a carbon material to form a particle catalyst; the electrode system is a two-electrode system; an anode in the two-electrode system comprises a dimensionally stable electrode, and an anode electrolyte is a sulfuric acid solution; and the two electrode systems are electrode systems in a flow battery stack structure. According to the preparation method, a flowing slurry and pulse electrodeposition combined method is adopted, so that metal particles are uniformly and stably loaded on a carbon material carrier, and gt is obtained within one-time preparation time of 1h; according to the method, laboratory-scale continuous synthesis of the granular catalyst is realized, and the method is simple in preparation process, mild in reaction condition and high in controllability.

This invention provides a system for predicting production scale up, comprising units of (a) a scale up theoretical unit that predicts process parameters of production scale up with input of experimental data obtained from lab scale trial; (b) a data driven unit that adjusts the process parameters obtained from scale up theoretical unit; and (c) an assistant decision-making unit that outputs parameters applicable for trial production in plant for next round of prediction based on the data obtained from data driven unit, said assistant decision-making unit is configured to map knowledge data from one or more knowledge databases including one or more decision trees. This invention also provides a method for predicting production scale up as well.

The application discloses an indoor fire source loading method for simulating real fire in an underground tunnel, S1: processing a test rock block in the shape of a cuboid; S2: selecting rock blocks as bases and placing the test rock block above the two bases with a distance between the two bases, so as to form a structure similar to a "pin" character; S3: setting a heating groove in the space between the two bases and the bottom surface of the test rock block; S4: spraying fireproof materials at the intersection gap between the bottom of the left and right side walls of the test rock block and the two bases, and at the intersection gap between the bottom of the front and back wall surfaces of the test rock block and the heating groove; S5: placing combustion materials in the heating groove and performing open fire source damage loading; and S6: extinguishing the open fire source and performing post-processing on the test rock block. The method can effectively realize single-side open fire loading on the rock block in a laboratory scale, is closer to the actual situation that the single-side wall of surrounding rock is affected by fire, and is more reasonable and intuitive for simulating and studying rock open fire damage in real fire in an underground tunnel.

The invention relates to the technical field of reef limestone pore filling, in particular to reef limestone pore filling experimental equipment for simulating a marine environment, which comprises a box body and a filling chamber arranged in the box body and used for placing a rock sample, the filling chamber is of a bottom opening structure, the lower part of the filling chamber is connected with a water permeable seat, and the lower part of the water permeable seat abuts against the box body; a water-permeable opening communicated with the bottom of the filling chamber is formed in the water-permeable base, a water injection hole is formed in the upper portion of the filling chamber and communicated with a liquid storage tank located on the outer side of the box body through a water injection pipe, a pressurizing assembly is connected to the liquid storage tank, and a water drainage opening is formed in the box body. The experimental equipment for the reef limestone pore filling technology aiming at the seawater reaction is innovatively provided, the pore filling technology based on the seawater chemical reaction can be explored under the laboratory scale, the real marine environment can be effectively simulated based on the experimental equipment, the repeatable reef limestone pore filling process can be achieved, and the experimental equipment is suitable for the reef limestone pore filling technology. And effective technical indexes are obtained.

A pressure-equalization holder is provided with a laboratory-scale reactor for measuring material deposition with a quartz crystal microbalance assembly. The pressure-equalization holder allows a process liquid from an interior of the laboratory-scale reactor to contact a liquid-facing crystal surface of a crystal of a quartz crystal microbalance assembly. The pressure-equalization holder also allows an inert fluid to contact an inert fluid-facing crystal surface of the crystal, where the inert fluid is at the same pressure as the process liquid.

The invention discloses a high-purity column chromatography purification method of a burning rate catalyst Cartosin, and aims to solve the problems of low purity and high HPLC (High Performance Liquid Chromatography) cost in the traditional method. According to the method, 200-300-mesh silica gel is used as a stationary phase for wet column packing, a Cartosin crude product is dissolved in a low-polarity solvent for sample loading, and a silica gel column is obtained; a mixed solvent composed of a non-polar solvent and a polar solvent is adopted as an eluent for gradient elution, a target fraction is monitored and collected through TLC, and then a product is obtained through rotary evaporation and vacuum drying; according to the method, the purity of cartosin can be increased from about 60% to 93.0% or above, equipment is simple, the cost is low, the process is stable, large-scale amplification from a laboratory to industrial production is easy, and the method is suitable for the requirement of a high-performance propellant.

Laboratory ball mill (1), in particular planetary or centrifugal ball mill on laboratory scale, comprising a support device (8) which is rotatably mounted about a central axis (20), at least one grinding station (10) with a receiving device (16) for at least one grinding vessel (12) that can be filled with grinding material and grinding media, wherein the receiving device (16) is rotatably mounted about an offset planetary axis (24) relative to the support device (8) and is carried by the latter about the central axis (20), a drive (7, 18) for the carrier device (8), a drive (22) for the grinding station (10), wherein the receiving device (16) has a cage (34) which forms a closed rigid frame in a plane parallel to the planetary axis (24) and has a clamping element (62) for axially clamping the grinding vessel (12) in the cage (34), wherein the cage (34) in the form of the closed rigid frame has a lateral opening (54) such that the grinding vessel (12) can be inserted into the cage (34) from the side through the lateral opening (54) for the grinding process and subsequently axially clamped in the cage (34), wherein the cage (34) absorbs the axial clamping force and after the grinding process the clamping of the grinding vessel (12) in the cage (34) can be released again and the grinding vessel (12) can be removed from the cage (34) also from the side through the lateral opening (54).

The present application relates to reef limestone pore filling technical field, concretely for a kind of reef limestone pore filling experimental equipment under simulated marine environment, including box and be set in box for placing filling chamber of rock sample, filling chamber is bottom opening structure, the lower part of filling chamber is connected with water-permeable seat, the lower part of water-permeable seat and box abut, water-permeable seat is opened with water-permeable mouth in filling chamber bottom intercommunication, the upper part of filling chamber is equipped with water injection hole, water injection hole is communicated with the liquid storage tank located outside the box by water injection pipe, liquid storage tank is connected with pressurizing assembly, box is opened with drain outlet.The present application innovatively proposes a kind of experimental equipment for the reef limestone pore filling technology of seawater reaction, can explore pore filling technology based on seawater chemical reaction under laboratory scale, based on the present application can effectively simulate real marine environment, and realize repeatable reef limestone pore filling process, obtain effective technical index.

The invention relates to the technical field of chemical process simulation, in particular to a gas-solid two-phase flow inter-phase heat transfer calculation method, system and equipment, and solves the problem that current accurate fine grid numerical simulation can only be limited to laboratory scale calculation and cannot be used for large-scale calculation through filtering analysis and fitting to obtain a gas-solid two-phase flow inter-phase heat transfer calculation model. In the process of amplifying to the industrial scale, the calculation cost cannot be borne by using fine grid simulation; and meanwhile, the problem that a high-precision mesoscale gas-solid interphase heat transfer model is lacked in coarse grid calculation is solved, and the calculation precision is ensured while the calculation efficiency is improved.

The utility model belongs to the technical field of ceramic production equipment, and particularly relates to small ball milling equipment for a laboratory. The device comprises a mounting frame, a ball milling assembly mounted on the mounting frame, a first supporting transmission assembly, a second supporting transmission assembly, a belt transmission assembly and a driving assembly, the first supporting transmission assembly and the second supporting transmission assembly are oppositely arranged in the axial direction of the ball milling assembly, located on the front side and the rear side of the ball milling assembly correspondingly and both in transmission connection with the ball milling assembly. The driving assembly is connected with the first supporting transmission assembly through the belt transmission assembly, drives the first supporting transmission assembly to rotate and drives the ball milling assembly to rotate in the axial direction of the ball milling assembly. In the small ball-milling equipment for the laboratory, the rotating shaft structure ensures the stability of the equipment and the convenience in maintenance, and can axially limit to prevent displacement of components; the rubber sleeve is easy to replace, cost is reduced, friction force is increased, and rotating speed is stable; in addition, the supporting transmission assembly is flexible in configuration and can be adjusted according to the ball milling requirement and the assembly size, and the universality and applicability of the equipment are enhanced.

The application discloses a numerical calculation method for calculating lean hydrogen turbulent combustion, and belongs to the field of hydrogen turbulent combustion numerical calculation. The method establishes an unsteady model containing a mixing fraction Z, a reaction progress variable C and a hydrogen mass fraction control equation, wherein the equation maps the influence of curvature; the control equation is solved, a pre-built small flame library is input to obtain components, temperature, chemical reaction source terms and diffusion coefficients; and a PIMPLE algorithm is used to couple pressure correction cycle iteration to update the flow field. Through dynamic characterization of the curvature effect and combination of the difference diffusion influence, the lean hydrogen flame local superadiabatic state can be efficiently captured, and a high-precision numerical tool is provided for laboratory scale turbulent hydrogen burner optimization.

A modular system for blow molding containers is provided.SOLUTION: The system may include a first portion, a second portion, and a third portion. The first portion and the second portion may each include a shell, a mold removably coupled to the shell, and a top plate. The third portion may include a base and a base mold. The mold may be 3D printed. The molds may collectively define a blow mold cavity. The modular system may be used at laboratory scale, pilot scale, or full production scale. The mold may be durable and smooth enough for full production scale. Some embodiments relate to a method for making a modular system for blow molding containers.SELECTED DRAWING: Figure 1

The application discloses a novel bismuth-based chelate CT contrast agent and a preparation method and application thereof. The synthesis method comprises the following steps: 2,6-pyridine dimethyl alcohol is reacted with chlorosulfoxide to obtain 2,6-bis(chloromethyl)pyridine; the 2,6-bis(chloromethyl)pyridine is reacted with N,N',N''-tris(p-tolylsulfonyl)divinyltriamine and an inorganic base in a solvent and is heated, is deprotected by concentrated sulfuric acid to obtain an intermediate pyclen; the pyclen is heated and reacted with a halogenated carboxylic acid ester under alkaline conditions in a polar organic solvent, is hydrolyzed to obtain a ligand product; and the ligand product is heated and chelated with a bismuth agent to obtain the target bismuth-based chelate. The application realizes the laboratory scale preparation of the small-molecule bismuth-based chelate CT contrast agent, and a non-ionic contrast agent is prepared, which has low osmotic pressure, high stability, high water solubility and good biological safety and is used for CT imaging of the digestive system, the urinary system and the circulatory system.

This invention provides a TEM sample, its preparation method, and its application. The TEM sample preparation method provided by this invention, without affecting the pore structure of the semiconductor device, first uses reactive ion etching to remove some residual polymer deposits blocking the pore openings on the semiconductor device. This enlarges the pore openings, preventing blockage and facilitating the entry of colloidal materials into the pore structure for filling and the deposition of precursor materials for atomic layer deposition. This enhances the clarity of the pore sidewalls, effectively improving the quality of the TEM sample and the final observation results. Furthermore, the TEM sample preparation method provided by this invention requires less equipment and technical investment, and the operation process is simpler and faster than Fab etching. It also enables batch laboratory-scale sample processing. In addition, compared to wet chemical etching cleaning techniques for removing residual polymers, it avoids problems such as chemical reagent residues at the bottom of deep pore structures and chemical reactant contamination.

The application discloses a synthesis method of a N,N-diphenyl-4-(pyridine-4-yl) aniline B-N coordination compound and application thereof. Under anhydrous and anaerobic conditions, (Me4N)B3H8 is reacted with I2 in THF to prepare an intermediate THF.B3H7, which is then reacted with a ligand N,N-diphenyl-4-(pyridine-4-yl) aniline to obtain a borane complex. Under anhydrous and anaerobic conditions, DMS.BH3 is reacted with the ligand N,N-diphenyl-4-(pyridine-4-yl) aniline in THF to obtain the borane complex. The synthesis method is simple, safe and high in yield, and is suitable for laboratory scale preparation. Optical property research shows that the prepared borane complexes all exhibit significant positive solvatochromic effect, aggregation-induced emission characteristics, mechanochromic performance and high quantum yield, and are ideal organic stimulus-responsive luminescent materials.

The invention provides a deep sea rare earth sediment foundation preparation method based on supergravity centrifugal physical simulation. The deep sea rare earth sediment foundation preparation method comprises the steps of similarity ratio design, solid phase formula design, initial layered filling in a model box, pore solution preparation, supergravity centrifugal accelerated consolidation and similarity evaluation of a model sample and a deep sea original sample. According to the technical scheme, deep sea stress and temperature boundaries can be reproduced at the same time in a laboratory scale, and the consolidation steady-state time is greatly shortened; the solid phase formula aligns the original sample mineral composition and the rare earth element REE spectrum, and pore water chemical alignment actually measures the seawater main ion strength and pH / Eh value; stable batch preparation can be achieved without open sea sampling, the cost and risk of going out of sea, salvaging and transporting are remarkably reduced, indoor low-cost large-scale preparation of deep sea rare earth sediment sea water samples is achieved, and large-scale indoor mechanics, seepage and process evaluation tests are supported; physical property / chemical / microcosmic / mechanical quantitative thresholds are provided, consistency acceptance and engineering application are facilitated, and batch-to-batch consistency and controllability are high.

The present invention relates to an automated integrated continuous bioprocess system and bioprocess that are capable of continuously producing therapeutic protein in an uninterrupted manner and scalable from laboratory to manufacturing scale. The present invention provides an automated integrated continuous bioprocess system and bioprocess for producing therapeutic protein, in which the system and process is controlled with one or more control system selected from supervisory control and data acquisition (SCADA) control system (110), proportional integral derivative (PID), programmable logic circuit (PLC), industrial PC (IPC), distributed control system (DCS), message relaying system and automated UPLC / HPLC sampling for online testing to run the system and process and in an uninterrupted manner and continuously produce therapeutic protein.

The utility model discloses an experimental type double fluid atomization spray drier belongs to spray drying equipment technical field, is open system, is especially used for the laboratory scale drying of aqueous solution. Including the organism, atomizer, by glass material one body and is not equipped with independent window's drying room, cyclone separator and fixed mounting in the built -in cloth bag filter of organism. The rated evaporation capacity of the equipment is 2 liters of water per hour, including condensing assembly and tail gas circulating assembly. The utility model structure is extremely compact, and the operation is simple, and the formula screening and small -batch sample preparation in the design of laboratory initial stage research and development are designed.

The present patent of invention describes an advanced method for producing kombucha, structured in distinct phases that separate the anaerobic and aerobic processes. In the first phase (anaerobic fermentation), sweetened tea and a symbiotic culture (SCOBY) are subjected to optimal conditions for yeast activity, generating an alcohol content of 1% to 8% within 2 to 8 days. The product is then transferred to an aerobic fermentation vessel, where the aerobic stage takes place, with continuous oxygenation and mechanical agitation. Temperature control and monitoring of pH and oxygen ensure a high conversion rate and stability of the bacterial culture after an initial adaptation period of 15 to 25 days. The final phase is characterized by a fed-batch regime every 18 to 24 hours, with harvesting of one-third of the volume and immediate replenishment, thereby enabling continuous and predictable fermentation and production. This set-up reduces the total processing time compared to traditional methods, providing a production time typical of laboratory scale for industrial use, whilst maintaining the product's sensory consistency and minimising the risk of contamination. The competitive advantages also include reduced production space requirements, lower operating costs, and greater large-scale production viability, resulting in a technically and commercially significant innovation in the fermented probiotic beverage sector.

The invention relates to a ball mill, in particular a mono-planetary or mono-centrifugal ball mill on a laboratory scale, with a counterweight to provide a counter-moment of inertia for the grinding station or stations, wherein the counterweight can be adjusted by means of an adjustment device to change the counter-moment of inertia adapted to the moment of inertia of the grinding station or stations. According to the invention, the ball mill includes an automatic drive for the adjustment device, by means of which the direction of adjustment of the counterweight can be effected independently of the direction of rotation of the support device.

A modular bioreactor system includes a set, or array, of smaller bioreactor chambers, such as laboratory-scale bioreactor chambers, which can be filled and drained together, while also being able to be isolated to permit the multiplexed bioreactor chambers to be used together to create a larger-scale reaction volume, thereby forming a manufacturing-scale bioreactor.

The application belongs to the technical field of perovskite material preparation, and particularly discloses a mixed halogen perovskite single crystal material and a preparation method thereof. 2.8 I 0.2 The obtained single crystal is treated at 20 DEG C and 90% RH for 3-6 h, surface defects are systematically repaired by using the moisture-induced lattice expansion and surface hydroxyl passivation mechanism, ion migration is inhibited, and the phase separation phenomenon is slowed down. The process is simple, controllable, and reproducible, and is suitable for laboratory-scale preparation and industrialization promotion.

The invention relates to the technical field of semiconductor materials, and particularly discloses a preparation method and application of a perovskite single crystal material. On the basis of the prepared MAPbBr3 single crystal, epitaxial growth of the MAPbBr2. 7Cl0.3 single crystal on the surface of the MAPbBr3 single crystal is achieved by changing the proportion of precursor halogen components, a continuous and complete single crystal heterostructure is formed, the structure can remarkably regulate and control the band gap structure of the material, the carrier separation efficiency and the photoelectric response capacity are improved, and the MAPbBr3 single crystal is finally used for preparing a high-performance photoconductive device. Moreover, the technological process is simple and convenient, the controllability is high, a secondary growth process combining inverse temperature crystallization with precursor component regulation and control is adopted, the operation steps are clear, the reproducibility is good, and the method is suitable for laboratory-scale preparation and future industrial popularization.

Provided is a method to initiate and analyze chemical derivatives formed from pyrotechnic smoke reactions. Milligram quantities of a lab-scale pyrotechnic smoke composition are reacted by encapsulation with a metal probe that is rapidly heated, which then sublimes the organic dye, allowing for the testing of all of the gas-phase products for identification by pyrolysis-gas chromatography-mass spectrometry. The thermally decomposed ingredients and new side product derivatives are identified at lower relative abundances compared to the intact organic dye. Any remaining residues within the thermal probe are optionally reconstituted into solution for further analysis by liquid chromatography-mass spectrometry if desired. The results are processed via a machine learning quantitative structure-activity relationship model that provides data related to health and environmental hazards.

The invention discloses a life cycle evaluation method of a bagasse refining method, which is based on a bagasse refining production process system pretreated by a tribasic acid-alcohol DES system, and comprises the following steps: (1) life cycle evaluation of a DES process under a laboratory scale; (2) constructing an industrial potential model; (3) establishing a multi-dimensional system evaluation method; (4) environment monetization evaluation; and (5) constructing a sustainable evaluation integrated evaluation model. According to the life cycle evaluation method, life cycle evaluation and monetization environment accounting are combined, a multi-dimensional and data-driven environment and economic decision basis is provided for industrial application of the DES technology, and popularization of a green process and implementation of circular economy are assisted. And the process controllability and amplification feasibility are improved. And the energy and material balance modeling in the process amplification process is more accurate and controllable. And an environment-economy coupling evaluation method is constructed, so that a quantitative basis can be provided for green technology path selection and policy making.

The invention discloses a three-chamber parallel structure nanofiber and a batch preparation method and equipment thereof. According to the preparation method, three spinning solutions are subjected to high-voltage electrostatic spinning at the same time; the two spinning solutions are respectively divided into microfluids to be led out through an array formed by two sets of series metal capillary tubes; the other spinning solution is divided into microfluids to be led out through a plurality of bottom through holes of the insulating container; the lower parts of the first series of metal capillary tubes and the second series of metal capillary tubes respectively penetrate through the insulating container in parallel and extend out of the two sides of the through hole in the bottom of the insulating container by 0.8-1.2 mm to form a plurality of common outlets of the three strands of spinning solution; the three spinning solutions are guided into a high-voltage electrostatic field in a transverse arrangement and parallel mode through a common outlet, and the three-chamber arrangement and parallel structure nanofiber is formed through direct stretching. According to the method, the limitation of a traditional needle type electrospinning technology in large-scale preparation of multi-chamber nanofibers in a laboratory is overcome, and the capability of preparing the nanofibers with the complete structure and the three-chamber parallel structure characteristic in a single-step, batch and large-scale mode is achieved.

The invention discloses a reef limestone lithification test device and a use method thereof. The reef limestone lithification test device comprises an injection assembly, a lithification test assembly, a collection assembly and a monitoring assembly. According to the device, CO2 provided by a CO2 low-temperature pump and artificial seawater provided by a seawater low-temperature pump are mixed in a low-temperature chamber to form CO2 seawater solutions with different concentrations, and then the CO2 seawater solutions are sprayed on coral debris samples to simulate the corrosion effect of acid rainwater on the coral island reef surface layer; the lithiation test box can also provide underground water dynamic conditions and different temperature and vertical pressure conditions for the coral clastic sample to simulate the natural diagenesis process of the reef limestone, and the spectrometer can monitor the volume change of calcite components in the coral clastic sample and the porosity change of the coral clastic sample in real time. The device provided by the invention can provide complex geological conditions required by diagenesis of the reef limestone, accelerates and simulates a corrosion process and a cementation process of the reef limestone from sand to rock in a laboratory scale, and provides technical guidance and a scheme for researching water-rock interaction of the reef limestone.

A light source includes a linear accelerator for accelerating an electron bunch to a relativistic energy. The light source further includes a first grating, downstream of the linear accelerator and arranged such that the electron bunch is transmitted through the grating to produce a diffraction pattern. The light source further includes an emittance exchange device, downstream of the first grating, that rotates the diffraction pattern to a direction substantially parallel to a direction of propagation of the electron bunch. The light source further includes a laser that produces a pulse of light. The light source is configured such that the pulse of light from the laser interacts with the electron bunch in an overtaking geometry at an interaction point, downstream of the emittance exchange device, while the diffraction pattern is substantially parallel to the direction of propagation of the electron bunch to produce light via inverse Compton scattering.

A modular system for blow molding a container. The system may include a first portion, a second portion, and a third portion. The first portion and second portion may each include a shell, a mold removably coupled to the shell, and a top plate. The third portion may include a base and a base mold. The molds may be 3D printed. The molds together may define a blow mold cavity. The modular system may be used at lab scale, pilot scale, or full production scale. The molds may be durable and smooth enough for full production scale. Some embodiments are directed to methods for making a modular system for blow molding a container.

The invention provides a method for simulating influence of industrial-scale dissolved carbon dioxide on anaerobic fermentation of saccharomyces cerevisiae, and belongs to the technical field of fermentation engineering. The invention provides three simulation methods: a DCO2 steady state simulation method comprises the following steps: carrying out anaerobic constant culture of saccharomyces cerevisiae in a bioreactor, adjusting the gas inlet ratio of N2 to CO2 to control the concentration of DCO2 at a target concentration and keep the concentration stable, and monitoring the change of metabolic indexes in real time; according to the DCO2 dynamic change simulation method, the concentration of DCO2 is changed according to a preset rule through program control, and metabolism reversibility is evaluated; according to the DCO2 periodic fluctuation simulation method, a high / low DCO2 double-chamber reactor system is constructed, and fermentation liquor is periodically mixed by setting circulation time. According to the method, the steady-state high concentration, dynamic change and periodic fluctuation characteristics of the DCO2 in the industrial reactor can be systematically reproduced under the laboratory scale, and an effective means is provided for evaluating the influence of the DCO2 on saccharomyces cerevisiae metabolism and the industrial fermentation amplification effect.