The invention provides an LS-SVM-based self-adaptive fault-tolerant GPS/INS integrated navigation method. The method is briefly characterized in that if an LS/SVM considers that a certain current sub-navigation system breaks down, the weight of the sub-navigation system in information fusion is lowered, the weight for other sub-navigation systems is increased, and therefore fault isolation is achieved. When the LS-SVM detects that fault information is repaired, the weight of the corresponding navigation sub-system is recovered to be normal, and therefore it is ensured that all normally-workingsub-navigation systems take part in information fusion, and the purpose of improving the precision of the integrated navigation system is achieved. Compared with the prior art, the navigation methodhas the advantages that when a fault exists, fault detection and isolation can be effectively achieved, and it is ensured that the navigation precision is not affected by fault information; when not fault exists, optimal information fusion of all the normally-working sub-navigation systems can be effectively achieved, and the navigation precision of the integrated navigation system is improved tothe maximum extent.