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1168 results about "Isolation system" patented technology

Penetration Enhancer Combinations for Transdermal Delivery

A high throughput screening and isolation system identifies rare enhancer mixtures from a candidate pool of penetration enhancer combinations. The combinations are screened for high penetration but low irritation potential using a unique data mining method to find new potent and safe chemical penetration enhancer combinations. The members of a library of chemical penetration enhancer combinations are screened with a high throughput device to identify “hot spots”, particular combinations that show higher chemical penetration enhancement compared to neighboring compositions. The irritation potentials of the hot spot combinations are measured to identify combinations that also show low irritation potential. A active component, such as a drug, is then combined with the combination in a formulation which is tested for the ability of the drug to penetrate into or through skin. It is then assessed whether the formulation can deliver the quantity of drug required, and animal tests are conducted to confirm in vivo the ability of the chemical penetration enhancer combinations to facilitate transport of sufficient active molecules across the skin to achieve therapeutic levels of the active molecule in the animal's blood. The invention provides specific unique and rare mixtures of chemical penetration enhancers that enhance skin permeability to hydrophilic macromolecules by more than 50-fold without inducing skin irritation, such as combinations of sodium laurel ether sulfate and 1-phenyl piperazine, and combinations of N-lauryl sarcosine and Span 20/sorbitan monolaurate.
Owner:RGT UNIV OF CALIFORNIA

Direct digital access arrangement circuitry and method for connecting DSL circuitry to phone lines

An isolation system is provided that is suitable for use in telephony, medical instrumentation, industrial process control and other applications. Preferred embodiments of the invention comprise a capacitive isolation barrier across which a digital signal is communicated. The system provides a means of communication across the isolation barrier that is highly immune to amplitude and phase noise interference. Clock recovery circuitry may be employed on one side of the isolation barrier to extract timing information from the digital signal communicated across the barrier, and to filter the effects of phase noise introduced at the barrier. Delta-sigma converters may be disposed on both sides of the isolation barrier to convert signals between analog and digital domains. An isolated power supply may also be provided on the isolated side of the barrier, whereby direct current is generated in response to the digital data received across the isolation barrier. A bidirectional isolation system is provided whereby bidirectional communication of digital signals is accomplished using a single pair of isolation capacitors. In preferred embodiments, the digital data communicated across the barrier consists of digital delta-sigma data signals multiplexed in time with other digital control, signaling and framing information. Finally, the isolation system may include a pulse transformer to accommodate ADSL circuitry, whereby power is transmitted through the pulse transformer.
Owner:SILICON LAB INC

Intelligent terminal isolation system and intelligent terminal isolation method both based on processor safety extension

Disclosed are an intelligent terminal isolation system and an intelligent terminal isolation method both based on processor safety extension. The intelligent terminal isolation system comprises a safety starting module, a transaction commission module, a communication agent module, a safety extension abstraction layer, a safety operating system, safety middleware, credible application modules and a common application module. The safety starting module simply initializes hardware environment of an intelligent terminal, and authenticates and guides the safety operating system. The communication agent module is responsible for encapsulation and communication of bottom layer data of the credible application modules and the common application module. The safety extension abstraction layer provides a uniform calling interface to the safety operating system. The safety operating system provides mutually independent operation space for the credible application modules in a whole safety domain and manages all software and hardware resources in the safety domain. The safety middleware is a core library related to implementation of safety functions and transaction commissions and provides related functional interfaces to credible applications. The intelligent terminal isolation system and the intelligent terminal isolation method aim to provide a complete safety isolation mechanism to the intelligent terminal and improve safety of software operation environment.
Owner:INST OF INFORMATION ENG CHINESE ACAD OF SCI

Damping-adjustable vibration isolation platform with quasi-zero stiffness

ActiveCN103899704ASolve the problem of isolating low frequencySolve the problem of ultra-low frequency vibrationNon-rotating vibration suppressionSemi activeBearing vibration
The invention discloses a damping-adjustable vibration isolation platform with quasi-zero stiffness. The damping-adjustable vibration isolation platform comprises a bearing assembly, a fixed platform frame and damping assemblies. The bearing assembly is used for bearing vibration isolation objects. The fixed platform frame is provided with an open end and a cavity which is communicated with the open end, and the bearing assembly and the damping assemblies are contained in the cavity. The damping assemblies comprise the damping-adjustable upper damping assembly and the damping-adjustable lower damping assembly which are arranged in the cavity in the longitudinal direction, and the bearing assembly is connected with the fixed platform frame through the upper damping assembly and the lower damping assembly. The vibration isolation platform solves the difficulty existing when a traditional linear vibration isolation system isolates low frequency or ultra-low frequency vibration, and also overcomes the defects that an active or semi-active control vibration isolation device is complex in structure, high in manufacturing cost, high in energy consumption and the like; the vibration isolation platform is simple in structure, applicable to wide-frequency-domain vibration isolation, capable of being widely applied to precise equipment with strict vibration isolation requirements and has good engineering adaptability. Besides, damping is simple and convenient to adjust.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY AND SCIENCE

Parallel mechanism based multidimensional vibration platform

ActiveCN104154170AAchieving Nonlinear StiffnessSolve the problem of isolating low frequencySpringsShock absorbersEngineeringUltra low frequency
The invention discloses a parallel mechanism based multidimensional vibration platform. Standard zero stiffness of a vibration isolation platform at the equilibrium position and nonlinear stiffness nearby the equilibrium position can be realized by setting certain structural parameters, and the problem about difficulty in isolating low-frequency or ultra-low-frequency vibration for a traditional linear vibration isolation system; stiffness and damping can be easily and conveniently adjusted, vibration isolation of broad frequency domains are satisfied, and good engineering applicability is achieved; the multidimensional vibration platform is high in bearing stiffness, low in movement stiffness, small in static deflection, low in dynamic inherent frequency and good in vibration isolation effect; inherent contradictions restricting the traditional vibration isolation system, namely the contradictions of low-frequency vibration transmissibility and high-frequency vibration attenuation, can be solved by flexible adjustment of the stiffness and damping; the height and the static equilibrium position of the entire platform can be changed by adjusting a shock absorber spring base in height, and the multidimensional vibration platform is applicable to vibration isolation of objects of different weight.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY AND SCIENCE
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