The invention discloses a cleaning agent for a liquid crystal display screen, belonging to the technical field of cleaning agents. The cleaning agent comprises the following raw materials by mass: 5-10% of fatty alcohol polyoxyethylene ether, 2-5% of isomeric alcohol polyoxyethylene ether, 0.2-0.5% of a fluorocarbon surfactant, 3-7% of sodium diisooctyl succinate, 2-5% of sodium dodecyl benzene sulfonate, 1-3% of cocamidopropyl betaine, 2-5% of trans-1,2-cyclohexanediaminetetraacetic acid, 1-3%of sodium polyacrylate, 2-4% of sodium metasilicate, 2-5% of hydroxyethylethylenediamine, 1-3% of polyvinyl alcohol, 3-7% of a solubilizer and 0.5-1% of a corrosion inhibitor, with the balance being deionized water. The cleaning agent of the invention has good ability in dissolving of liquid crystalmaterials, oil stains, dust, etc., and liquid crystal materials, oil stains, dust and the like are emulsified and dispersed in the cleaning agent and are thus separated from a to-be-cleaned surface; and the cleaning agent has good cleaning effect, is free of residues on the surface of a liquid crystal cell and low in corrosivity to liquid crystal display screens, and does not affect the physical properties of liquid crystal display screens.