The invention discloses a tank box without cleaning and disinfection, and relates to the field of tank boxes, the tank box comprises a tank box, a liquid bag is mounted in the tank box, a sealing cover is connected to the side surface of the tank box, the end part of the liquid bag is connected with an opening connected with the sealing cover in a clamping manner, the outer side of the liquid bag is sleeved with a protective sleeve, and the protective sleeve is connected with the liquid bag in a clamping manner. A protective sleeve is arranged on the inner wall of the tank box, a limiting sleeve is arranged on the outer wall of the protective sleeve, a limiting rod matched with the limiting sleeve is arranged on the inner wall of the tank box, the limiting sleeve is connected to the outer side of the limiting rod in a sleeving mode, a buffer pad is connected to the side face, away from the sealing cover, of the interior of the tank box, and the buffer pad is attached to the end of the liquid bag to limit the liquid bag. In addition, in the liquid transportation process, gas with the appropriate temperature can be injected into the tank box through the heat exchange mechanism, the temperature of the liquid bag is controlled through the gas, the temperature of the liquid bag is prevented from being too high or too low, and the liquid maintaining effect is improved.