A wire-stripping machine for a medium-high voltage cable comprises a frame, a speed reducer, a motor, a coupler, a gear, a bearing block, a bearing saddle, pressing wheels, blades, clamping devices and a frame cover plate. Two groups of pressing wheels are arranged on the frame side by side, each group of pressing wheels includes an upper pressing wheel and a lower pressing wheel which are oppositely mounted, a space for penetrating the cable is reserved between each upper pressing wheel and the corresponding lower pressing wheel, the working surface of each upper pressing wheel is semicircular, the working surface of each lower pressing wheel is umbrella-shaped, the blades are clamped in the middles of the working surfaces of the upper pressing wheels in the wire outlet direction, one clamping device is arranged above each group of pressing wheels, one of the lower pressing wheels of the two groups of pressing wheels is mounted on a driving shaft, the other one of the lower pressing wheels of the two groups of pressing wheels is mounted on a driven shaft, the driving shaft is connected with the speed reducer and the motor through the coupler, the gear is mounted on the driving shaft and transmits power to a transmission gear through an intermediate gear, and the transmission gear is mounted on the driven shaft and drives the other lower pressing wheel. By the aid of the wire-stripping machine, a wire insulating layer can be automatically separated from metal, wire-stripping efficiency is improved, labor cost is saved, and loss is furthest reduced.