Adipose mesenchymal stem cell sampling device

By designing an automated adipose mesenchymal stem cell sampling device, the shearing device is used to achieve uniform shearing of adipose tissue, solving the problems of difficulty and low efficiency of traditional manual shearing operations, and improving the efficiency of subsequent centrifugal treatment.

CN222331922UActive Publication Date: 2025-01-10SHANDONG JINGYUAN BIOTECH CO LTD
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Patent Information

Application Number
CN202420846512.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-23
Publication Date
2025-01-10
Estimated Expiration
2034-04-23

AI Technical Summary

Technical Problem

During the sampling process of mesenchymal stem cells, traditional manual cutting of fat tissue is difficult to operate, and it is easy to lead to insufficient or uneven cutting of fat, affecting the efficiency of subsequent centrifugation.

Method used

A fat mesenchymal stem cell sampling device is designed, including a shear device, which uses telescopic rods and blade motors to achieve automated fat tissue shearing to ensure shear uniformity and efficiency.

Benefits of technology

The shearing efficiency of adipose tissue is improved, the problems of insufficient shearing and unevenness are avoided, and the efficiency of subsequent centrifugation is ensured.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of biomedical treatment, in particular to an adipose-derived mesenchymal stem cell sampling device which comprises a shell, a centrifugal motor is fixedly connected to the inner end of the bottom side of the shell, a rotating shaft is in output connection with the upper end of the centrifugal motor, and a plurality of centrifugal frames are fixedly connected to the outer end of the rotating shaft; the upper end of the centrifugal tube is sleeved with a test tube cover in a threaded mode, and the lower end of the test tube cover is fixedly connected with a shearing device. The adipose mesenchymal stem cell sampling device has the beneficial effects that by arranging the shearing device, adipose tissues can be directly sheared through the shearing device when being sheared, so that the shearing efficiency is improved, the sheared adipose tissues are ensured not to have the phenomena of insufficient and non-uniform shearing, and the sampling quality of the adipose mesenchymal stem cells is improved. And the high efficiency of subsequent centrifugal treatment is ensured.
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Description

Technical Field

[0001] The utility model relates to the field of biomedicine, in particular to an adipose mesenchymal stem cell sampling device. Background Art

[0002] Mesenchymal stem cells are a type of pluripotent stem cells that have all the common properties of stem cells, namely, self-renewal and multidirectional differentiation capabilities. They are also the most widely used in clinical applications. When used in combination with hematopoietic stem cells, they can improve the success rate of transplantation and accelerate hematopoietic reconstruction. When patients receive high-dose chemotherapy, the infusion of mesenchymal stem cells together with hematopoietic stem cells can significantly accelerate the recovery time of the patient's blood cells, and it is safe and has no adverse reactions. When sampling mesenchymal stem cells, a centrifugal device is required for centrifugal sampling. Before centrifugal sampling, the fat tissue needs to be cut into pieces.

[0003] Traditional shredding processing usually requires staff to manually shred the fat tissue using scissors, which has certain operating difficulties during the shredding process. In addition, the manually shredded fat tissue may have a certain impact on the subsequent centrifugal processing due to insufficient and uneven shredding. Therefore, the utility model proposes an adipose mesenchymal stem cell sampling device to solve the above problems. Utility Model Content

[0004] The purpose of the utility model is to provide an adipose mesenchymal stem cell sampling device to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an adipose mesenchymal stem cell sampling device, the adipose mesenchymal stem cell sampling device comprising: a shell, the inner end of the bottom side of the shell is fixedly connected to a centrifugal motor, the upper end output of the centrifugal motor is connected to a rotating shaft, the outer end of the rotating shaft is fixedly connected to a plurality of centrifugal racks; a centrifugal tube, the upper end of the centrifugal tube is threadedly sleeved with a test tube cover, and the lower end of the test tube cover is fixedly connected to a shearing device.

[0006] Preferably, the shearing device comprises a telescopic rod, a blade sleeve is fixedly connected to the lower end of the telescopic rod, and an upper blade is fixedly connected to the outer end of the blade sleeve.

[0007] Preferably, the inner end of the blade sleeve is fixedly connected to a blade motor, the end of the blade motor is fixedly connected to a blade shaft, and the end of the blade shaft is fixedly connected to a lower blade.

[0008] Preferably, the blade shaft sleeve is arranged in the blade sleeve.

[0009] Preferably, a telescopic rod is fixedly connected to the lower end of the test tube cover.

[0010] Preferably, a clamping sleeve is fixedly connected to the end of the centrifugal frame, and a centrifuge tube is sleeved in the clamping sleeve.

[0011] Compared with the prior art, the beneficial effects of the utility model are:

[0012] The adipose mesenchymal stem cell sampling device proposed by the utility model is provided with a shearing device, so that the adipose tissue can be directly sheared by the shearing device during the shearing process, thereby improving the shearing efficiency and ensuring that the sheared adipose tissue will not be insufficiently and unevenly shredded, thereby ensuring the high efficiency of subsequent centrifugal processing. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0014] Figure 2 It is a schematic diagram of the connection of some structures of the utility model;

[0015] Figure 3 This is a schematic diagram of the internal structure of the utility model;

[0016] Figure 4 It is an enlarged schematic diagram of part of the structure of the utility model.

[0017] In the figure: 1 housing, 2 centrifugal motor, 3 shaft, 4 centrifugal frame, 5 centrifugal tube, 6 test tube cover, 7 clamping sleeve, 8 telescopic rod, 9 blade sleeve, 10 lower blade, 11 upper blade, 12 blade shaft, 13 blade motor. DETAILED DESCRIPTION

[0018] In order to make the purpose and technical solution of the utility model clearly and completely described, and the advantages more clearly understood, the embodiments of the utility model are further described in detail in conjunction with the accompanying drawings. It should be understood that the specific embodiments described here are part of the embodiments of the utility model, not all of the embodiments, and are only used to explain the embodiments of the utility model, and are not used to limit the embodiments of the utility model. All other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0019] Embodiment 1

[0020] See also Figure 1-Figure 4The utility model provides a technical solution: a fat mesenchymal stem cell sampling device, which includes: a shell 1, a centrifugal motor 2 is fixedly connected to the inner end of the bottom side of the shell 1, a rotating shaft 3 is connected to the output of the upper end of the centrifugal motor 2, and a plurality of centrifugal frames 4 are fixedly connected to the outer end of the rotating shaft 3, and the centrifugal motor 2 is used to drive the rotating shaft 3 to rotate so that the centrifugal frame 4 can achieve a centrifugal effect; a centrifugal tube 5, a test tube cover 6 is threadedly sleeved on the upper end of the centrifugal tube 5, a shearing device is fixedly connected to the lower end of the test tube cover 6, and a telescopic rod 8 is fixedly connected to the lower end of the test tube cover 6, and the telescopic rod 8 can be automatically retracted and used for preventing the shearing device from hindering the stem cell sampling during centrifugal rotation, and a clamping sleeve 7 is fixedly connected to the end of the centrifugal frame 4, and the centrifugal tube 5 is sleeved in the clamping sleeve 7.

[0021] Embodiment 2

[0022] On the basis of embodiment 1, the shearing device includes a telescopic rod 8, a blade sleeve 9 is fixedly connected to the lower end of the telescopic rod 8, an upper blade 11 is fixedly connected to the outer end of the blade sleeve 9, a blade motor 13 is fixedly connected to the inner end of the blade sleeve 9, a blade shaft 12 is fixedly connected to the end of the blade motor 13, a lower blade 10 is fixedly connected to the end of the blade shaft 12, the blade shaft 12 is sleeved in the blade sleeve 9, the upper blade 11 is fixed, and the lower blade 10 rotates to achieve cutting.

[0023] In actual use, first add the pretreated fat tissue into the centrifuge tube 5, and then cover the test tube cover 6. The lower end of the test tube cover 6 is fixedly connected to the telescopic rod 8, and the lower end of the telescopic rod 8 is fixedly connected to the blade sleeve 9. The outer end of the blade sleeve 9 is fixedly connected to the upper blade 11, and the inner end of the blade sleeve 9 is fixedly connected to the blade motor 13. The end of the blade motor 13 is fixedly connected to the blade shaft 12, and the end of the blade shaft 12 is fixedly connected to the lower blade 10. The blade shaft 12 is sleeved in the blade sleeve 9, the upper blade 11 is fixed, and the lower blade 10 rotates to achieve cutting. The telescopic rod 8 can automatically retract, and is used to prevent the shearing device from hindering the stem cell sampling when the centrifuge rotates, so that sampling can be carried out.

[0024] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A fat-derived mesenchymal stem cell sampling device, characterized in that: The adipose mesenchymal stem cell sampling device comprises: A housing (1), wherein the inner end of the bottom side of the housing (1) is fixedly connected to a centrifugal motor (2), the upper end of the centrifugal motor (2) is output-connected to a rotating shaft (3), and the outer end of the rotating shaft (3) is fixedly connected to a plurality of centrifugal frames (4); A centrifuge tube (5), wherein a test tube cover (6) is threadedly sleeved on the upper end of the centrifuge tube (5), and a shearing device is fixedly connected to the lower end of the test tube cover (6).

2. The adipose-derived mesenchymal stem cell sampling device according to claim 1, characterized in that: The shearing device comprises a telescopic rod (8), the lower end of the telescopic rod (8) is fixedly connected to a blade sleeve (9), and the outer end of the blade sleeve (9) is fixedly connected to an upper blade (11).

3. The adipose-derived mesenchymal stem cell sampling device according to claim 2, characterized in that: The inner end of the blade sleeve (9) is fixedly connected to a blade motor (13), the end of the blade motor (13) is fixedly connected to a blade shaft (12), and the end of the blade shaft (12) is fixedly connected to a lower blade (10).

4. The adipose-derived mesenchymal stem cell sampling device according to claim 3, characterized in that: The blade rotating shaft (12) is sleeved in the blade sleeve (9).

5. The adipose-derived mesenchymal stem cell sampling device according to claim 1, characterized in that: The lower end of the test tube cover (6) is fixedly connected with a telescopic rod (8).

6. The adipose-derived mesenchymal stem cell sampling device according to claim 1, characterized in that: A clamping sleeve (7) is fixedly connected to the end of the centrifugal frame (4), and a centrifugal tube (5) is sleeved inside the clamping sleeve (7).

Citation Information

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