103results about How to "Enhanced response signal" patented technology

A fluorescence-based method for highly sensitive and selective detection of analyte molecules is proposed. The method employs the energy transfer between two or more fluorescent chromophores in a carefully selected polymer matrix. In one preferred embodiment, signal amplification has been achieved in the fluorescent sensing of dimethyl methylphosphonate (DMMP) using two dyes, 3-aminofluoranthene (AM) and Nile Red (NR), in a hydrogen bond acidic polymer matrix. The selected polymer matrix quenches the fluorescence of both dyes and shifts dye emission and absorption spectra relative to more inert matrices. Upon DMMP sorption, the AM fluorescence shifts to the red at the same time the NR absorption shifts to the blue, resulting in better band overlap and increased energy transfer between chromophores. In another preferred embodiment, the sensitive material is incorporated into an optical fiber system enabling efficient excitation of the dye and collecting the fluorescent signal form the sensitive material on the remote end of the system. The proposed method can be applied to multichromophore luminescence sensor systems incorporating N-chromophores leading to N-fold signal amplification and improved selectivity. The method can be used in all applications where highly sensitive detection of basic gases, such as dimethyl methylphosphonate (DMMP), Sarin, Soman and other chemical warfare agents having basic properties, is required, including environmental monitoring, chemical industry and medicine.

A porous geological formation contains electrolytic fluid. During the geophysical prospecting of the formation, a region of interest of the formation where the electrolytic fluid is found is stimulated with an excitation signal. The excitation signal corresponds to an energy of a first type. The excitation signal is converted in the region of interest into a response signal. The response signal corresponds to an energy of a second type. The response signal is detected. An electric polarisation is applied to the region of interest so as to strengthen the response signal relative to what it would be in the absence of polarisation. The electric polarisation comes about by means of a continuous or quasi-continuous polarising electric field. The polarising electric field is modulated in frequency with a frequency which is low relatively to the excitation frequency.

The invention is a sensor, in particular to a subcutaneous tissue-intervening needle-shaped glucose sensor and a preparation method thereof. It includes a base, and the bottom of the base is provided with a working electrode, a counter electrode and a reference electrode, and the working electrode, the counter electrode and the reference electrode form a split needle-shaped three-electrode system. The subcutaneous tissue-intervening needle-like glucose sensor and the preparation method thereof have a compact structure, improved operation performance, and improved service life.

The invention discloses an NO2 gas sensor based on a covalent triazinyl two-dimensional polymer as well as a preparation method and application of the NO2 gas sensor. The sensor comprises a gas sensitive material and a ceramic interdigital electrode, the gas sensitive material is coated on the surface of the ceramic interdigital electrode to form a sensing film, and the thickness of the sensing film is 6-10nm; the gas sensitive material includes a single layer of or 2 to 4 layers of triazinyl two-dimensional polymer nanosheets, and the thickness of the single layer is 1-2.5 nm. The sensor prepared by the invention has the advantages of high NO2 gas response value, stability and restorability, and can work at room temperature.