The invention discloses a positive and negative stiffness parallel-connection low-frequency vibration isolation device of a coupling dynamic vibration absorber. A cam-ball-spring mechanism symmetry arrangement is taken as a negative stiffness mechanism, the negative stiffness mechanism is in parallel connection with a positive stiffness spring to form a quasi-zero stiffness vibration isolator, andon this basis, a dynamic vibration absorber is additionally arranged to form a positive and negative stiffness parallel-connection vibration isolation system of a coupling linear vibration absorber;based on the anti-resonance characteristic in a multi-degree-of-freedom system, the additional dynamic vibration absorber is used for absorbing the vibration energy of a main system, so that the vibration energy is transferred to the dynamic vibration absorber to weaken the vibration intensity of a main structure; when the exciting force frequency is close to the inherent frequency of the dynamicvibration absorber, the power provided by the dynamic vibration absorber to the main system gradually offsets the exciting force acting on the main system, so that the amplitude of the main system canbe reduced sharply; and the vibration absorber with proper quality, stiffness and damping is selected, so that the force transmission rate curve can be moved leftwards, the initial vibration isolation frequency is reduced, the vibration isolation frequency bandwidth is expanded, and the low-frequency vibration isolation performance of the system is improved. The vibration isolation device has high static stiffness and low dynamic stiffness, has wide vibration isolation bandwidth and can be popularized and applied to low-frequency vibration control.