146results about How to "Maximize sensitivity" patented technology

Systems and methods for joint replacement are provided. The systems and methods include a surgical orientation device and at least one orthopedic fixture. The surgical orientation device and orthopedic fixtures can be used to locate the orientation of an axis in the body, to adjust an orientation of a cutting plane or planes along a bony surface, to distract a joint, or to otherwise assist in an orthopedic procedure or procedures.

An obstacle avoidance system for obstacle detection in an opaque material. The system includes at least one electromagnetic signal source adapted to produce an electromagnetic source signal suitable for transmission through the opaque material, at least one electromagnetic signal detector adapted to receive reflected electromagnetic energy signals from discontinuities in the opaque material encountered by the electromagnetic source signal, and a reflected electromagnetic energy signal processor suitable for determining a presence of obstructions and / or strata variations within the opaque material. The system is preferably integral with a head element suitable for traversing the opaque material, for example a subterranean drill bit.

A control system and apparatus for use with laser ionization is provided. In another aspect of the present invention, the apparatus includes a laser, pulse shaper, detection device and control system. A further aspect of the present invention employs a femtosecond laser and a mass spectrometer. In yet other aspects of the present invention, the control system and apparatus are used in MALDI, chemical bond cleaving, protein sequencing, photodynamic therapy, optical coherence tomography and optical communications processes.

The invention provides microfluidic systems for altering the solution environment around a nanoscopic or microscopic object, such as a sensor, and methods for using the same. The invention can be applied in any sensor technology in which the sensing element needs to be exposed rapidly, sequentially, and controllably, to a large number of different solution environments whose characteristics may be known or unknown.

The present invention relates to a magnetic resonance spectroscopic imaging (MRSI) method, specifically to a magnetic resonance spectroscopic imaging method with up to three spatial dimensions and one spectral dimension. Interleaving dynamically switched magnetic field gradients into the spectroscopic encoding scheme enables multi-region shimming in a single shot to compensate the spatially varying spectral line broadening resulting from local magnetic field gradients. The method also employs sparse spectral sampling with controlled spectral aliasing and nonlinear sampling density to maximize encoding speed, data sampling efficiency and sensitivity.

The present invention provides a sensor, such as a biosensor, comprising at least one self-assembled monolayer (SAM) comprising analyte-sensitive groups, such as glucose-sensitive groups, attached to the surface of the outer wall of a carbon nanotube (CNT), such as a single-walled carbon nanotube (SWNT), by terminal groups, which bind to a thin layer of a metal or metal oxide, which has been deposited on the surface of the outer wall of the nanotube.

In an actively illuminated imaging system, illumination of a segmented scene is synchronized with an image sensing period. A scene is segmented into a plurality of scene portions utilizing a segmented lens. In an aspect, a first scene portion is illuminated when an imager is actively collecting photogenerated charge from the first scene portion, and a second scene portion is illuminated when an imager is actively collecting photogenerated charge from the second scene portion. The sensitivity of an image sensor is maximized, while simultaneously minimizing the amount of light that must be supplied to illuminate a scene. An irradiance pattern is varied allowing a more uniform distribution of light. Bands of varying wavelength, polarization, and light intensity may be variously applied to illuminate individual scene segments, as needed to enhance an identification of an object in the scene. The present invention is particularly useful with high frame rate imaging systems.

A method of surgically positioning an electrode array at a desired implantation location relative to a nerve. A temporary probe electrode is temporarily positioned adjacent to the nerve and at a location which is caudorostrally separate to the desired implantation location of the electrode array. The implanted position of the probe electrode is temporarily fixed relative to the nerve. During implantation of the electrode array, electrical stimuli are applied from one of the temporarily fixed probe electrode and the electrode array, to evoke compound action potentials on the nerve. Compound action potentials evoked by the stimuli are sensed from at least one electrode of the other of the temporarily fixed probe electrode and the electrode array. From the sensed compound action potentials a position of the electrode array relative to the nerve is determined.

A magnetic field sensor relies on variations in permeability of magnetic material to detect an external field. An exemplary magnetic field sensor includes a lengthwise extending sensing element, and a coil wound about the sensing element. The sensing element may be formed as a number of geometrically and magnetically similar or identical conductive cores that are ferromagnetic, driven by an AC magnetic field. The multiple conductive cores are connected in parallel. An external magnetic field changes the magnetic characteristics of the sensing element and induces a change in electric potential of the induction coil. The sensor output is proportional to the number of conductive cores.