The application relates to a horizontal well section multi-cluster fracturing temporary plugging effect evaluation method, which comprises the following steps: acquiring construction data in real time, acquiring a temporary plugging agent in-place
pressure increase value according to the construction data; acquiring construction pressures before and after a temporary plugging agent injection opportunity, wherein the sand concentration is zero and the
discharge capacity is equal, and the difference is obtained to obtain a same
discharge capacity
pressure increase value; acquiring construction data points before and after the temporary plugging agent injection opportunity, wherein the sand concentration is equal and the
discharge capacity is equal, and the curve superposition is carried out to calculate the percentage of construction data points with
positive pressure difference before and after the temporary plugging agent injection opportunity, and the
positive pressure difference ratio is obtained; determining temporary plugging
effective time temporary plugging agent in-place
pressure increase index value, same discharge capacity pressure increase index value and
positive pressure difference ratio index value according to mechanical differences among clusters in a reservoir section; comparing the temporary plugging agent in-place pressure increase value, the same discharge capacity pressure increase value and the positive
pressure difference ratio with corresponding index values to obtain three discrimination results, introducing a
weight coefficient to integrate the three discrimination results, and determining whether the temporary plugging is effective in real time.