103results about How to "Good sensitivity" patented technology

The present invention relates to a computationally efficient method of finding patterns in any data that can be expressed in the form of arrays of binary features or arrays of categorical features. This includes data represented by continuous-valued attributes that can be transformed to a categorical representation, such as the discovery of patterns of genetic variability that may be causally related to diseases or traits, as well as the discovery of patterns of protein biomarkers that may be used for medical diagnostics, prognostics, and therapeutics. The invention further relates to a program storage device having instructions for controlling a computer system to perform the methods, and to a program storage device containing data structures used in the practice of the methods.

A sensor system for viewing the light energy of a scene has an imaging detector which converts incident light energy into an electrical signal. Two colors are separately imaged by the detector in two imaging regions. The imaging system for each color includes a color filter positioned between the scene and the respective region of the detector, an optical train that focuses filtered color scene energy, and an optical fiber bundle having an input end that receives the respective color scene energy from the optical train and an output end that directs the color scene energy onto the respective region of the detector using a nonlinear mapping. The optical fiber bundle is formed of a plurality of optical fibers wherein each of the optical fibers has an input shape and size at its input end and an output shape and size at its output end. The output shape and size are different from the input shape and size. The sensor system further includes an electronic device operable to read the electrical signal of the detector, and image-processing electronics.

A device (17) is provided for tensioning a flexible band (3) used to maintain a bone element on an implant. The device includes a rod (18) having a first end (19) provided with means (20) for bearing on the implant, a movable part (32) for hooking the flexible band onto a portion (28) of the device, and means (34) for adjustably locking the movable part in translation in relation to the portion of the device. The rod (18) includes a gripping handle (26) at the second end (27) thereof. The aforementioned portion of the device forms an angle α with the rod (18) to which it is rigidly connected at an intermediary point, the direction of the band being altered at an angle, and the aforementioned adjustable locking means (34) includes manual screwing means (35) for actuating the movable part.

Methods and systems are described to automatically obtain and analyze a lung airway gas sample from the breath of a person for compositional analysis. These techniques may provide an improved method for example for accurately and reliably measuring nitric oxide for asthma assessment in young children and non-cognizant patients.

A signal intercept and analysis processor for a wideband intercept receiver system including at least one wideband receiver has a signal detector operatively connectable to the wideband receiver and a signal extractor operatively connected to the signal detector and connectable to the wideband receiver for performing signal extraction directly on a wideband signal output of the receiver and for performing the signal extraction only upon detection of a signal by the signal detector. The signal detector includes a generator of a coarsely sampled or decimated time-frequency representation of the wideband signal output. The time-frequency representation is decimated or coarsely sampled in time compared to an inverse frequency filter bandwidth used in the time-frequency representation. The generator preferably includes a digital filter bank. The digital filter bank in turn may include means for performing a sequence of windowed FFTs on samples of the wideband signal output, wherein a stride between consecutive one of the FFTs is considerably larger than a length of each of the FFTs.

An image sensor has a substrate, a dielectric layer positioned on the substrate, a pixel array including a plurality of pixels defined on the substrate, a shield electrode positioned between any two adjacent pixel electrodes of the pixels, a photo conductive layer positioned on the shield electrode and the pixel electrodes, and a transparent conductive layer covering the photo conductive layer.

The invention relates to a real-time fluorescent polymerase chain reaction (PCR) detecting kit, in particular to a kit for early and rapidly diagnosing coxsackievirus A16 infection by a real-time fluorescent quantitative PCR technology. Aiming at a specific nucleotide sequence designing primer and a probe of coxsackievirus A16, the kit adopts a one-step fluorescent reverse transcription-polymerase chain reaction (RT-PCR) method to amplify a sample, judges whether the sample is provided with the coxsackievirus A16 or not according to an amplification curve and quantifies virus contents by a linear quantitative reference product. The kit can detect and quantitatively analyze the coxsackievirus A16 in the samples including feces, blood serum, throat swab, cerebrospinal fluid, bleb fluid, and the like.

A liquid-condition detection element is provided which exhibits good sensitivity while having appropriate strength. The detector element forms part of a liquid-condition detection sensor in which breakage of the detection element is combated and which can accurately detect the condition of liquid. The detection element includes first and second ceramic insulating layers formed by simultaneous firing and a heat-generating resistor sealed in a liquid tight manner between the insulating layers. The resistor has a resistance varying with temperature, and is, in use, immersed in liquid. The first insulating layer is thinner than the second layer. A detection section of the liquid-condition detection sensor detects the condition of a liquid (e.g., the concentration of a particular component in the liquid) on the basis of an output signal from the heat-generating resistor.

A magnetic sensor including a ferromagnetic tunnel junction, comprises a free layer 10 a magnetic direction of which freely rotates, and a barrier layer 11 formed on the free layer and reduces a thickness in a first region, the free layer in a region corresponding to the first region functioning as a sensor portion for sensing an external magnetic field. Such magnetic sensor can provide magnetic sensors, magnetic heads and magnetic encoders having high sensitivity. Furthermore, such magnetic sensor can provide magnetic heads which are adaptable to high recording density of magnetic storage mediums, and hard disk devices of large storage capacities using the magnetic heads.

The invention discloses a reagent box for simultaneously detecting diversified components of animal origin and application of the reagent box. Fluorescent primer multiplex amplification and capillary electrophoresis methods are combined with one another, so that the 12 components of animal origin can be simultaneously detected by the aid of the reagent box, and a plurality of groups of specific primers can be designed by the aid of Escherichia coli and selected STR (short tandem repeat) sequences of dogs, cattle, sheep, fish, pigs, ducks, chickens, rabbits, cats, horses and rats. The specific primers include specific primers PEZ1 of the dogs, specific primers BM2113 of the cattle, specific primers MAF33 of the sheep, specific primers HLJ392 of the fish, specific primers SW742 of the pigs, specific primers CAUD056 of the ducks, specific primers MCW248 of the chickens, specific primers Sat7 of the rabbits, specific primers FCA955 of the cats, specific primers HMS3 of the horses, specific primers cds of the rats and specific primers CFS073 of the Escherichia coli. The reagent box and the application have the advantages that the reagent box is good in specificity and high in sensitivity, and origin of meat can be quickly determined; multiplex amplification systems contain the primers of the Escherichia coli, and accordingly whether meet foods and products are contaminated by Escherichia coli or not can be simultaneously determined.

The invention discloses a colloidal gold immunochromatography test strip for detecting a bovine rotavirus, and a preparation method and an application thereof. The test strip includes a sample pad, acolloidal gold pad, a nitrocellulose membrane and an absorbent filter paper which are sequentially connected from left to right, and also includes a PVC base plate positioned at the bottom, wherein the PVC base plate is used to provide an assembling platform, the nitrocellulose membrane is provided with a quality control line formed by spraying a goat anti-mouse IgG and a detection line formed byspraying a rabbit anti-bovine rotavirus polyclonal antibody, the colloidal gold pad is coated with a colloidal gold particle-labeled mouse anti-bovine rotavirus VP6 protein monoclonal antibody, and the sample pad provides a position for adding a sample to be detected, wherein the mouse anti-bovine rotavirus VP6 protein monoclonal antibody is secreted by a hybridoma cell strain preserved in China General Microbiological Culture Collection Center with the preservation number being CGMCC NO.14726. The test strip prepared in the invention has the advantages of good sensitivity, high specificity, simplicity and rapidness in operation, and suitableness for onsite detection.

Sensing methods are sought to overcome the disadvantages—poor sensitivity and selectivity, poor long-term stability, and undeployable. Sensor of these teachings for detecting and recognizing target molecules includes a layer of molecularly imprinted polymer disposed on a single layer graphene sheet. In some instances, the sensor of these teachings also includes a sensing circuit configured to detect and report impedance changes in a layer of molecularly imprinted polymer disposed on a single layer grapheme sheet, the impedance changes caused by the binding of the target molecules to the molecularly imprinted polymer.

The invention relates to the field of biomedicine and particularly relates to an antibody compound for detecting human prepalin retinol binding protein 4, as well as an immunochromatography test card. A monoclonal antibody 1 of human prepalin retinol binding protein 4 is connected with colloidal gold granules, and then the antibody compound is obtained and used for preparing the immunochromatography test card for human prepalin retinol binding protein 4, and a kit. The invention has the advantages of good sensitivity, strong specificity and the like.

A multi-ion potential sensor is disclosed. The multi-ion potential sensor comprises a substrate, a conductive layer, an isolation layer, a tin oxide (SnO₂) layer and a selective layer. The conductive layer comprises a plurality of independent conductive areas, wherein every conductive area comprises a readout area, a transmissive area and a sensing area, and the transmissive area of every conductive area is packaged by the isolation layer. The tin oxide layer comprises a plurality of independent tin oxide areas, wherein every tin oxide area is deposited on the sensing area, and the selective layer comprises a plurality of independent selective areas, wherein every selective area is set on the tin oxide area. The multi-ion potential sensor has various advantages, such as good sensitivity, low cost, simplicity, disposable, portable and data acquisition by a computer for different applications.

The invention discloses an on-line detection method for SF6 gas in electrical equipment. On-line mass spectrometer is employed for detection analysis. An employed ionization source of the on-line mass spectrometer is a photoelectron ionization source. A sample gas is firstly subjected to dedusting processing before being introduced, and directly enters a sample-introduction system, and is introduced to the on-line mass spectrometer under the condition of constant temperature by a capillary. The method does not need any sampled subjected to pretreatment, the detection speed is fast, the analysis time and the processing time are in 1 min, the sensitivity is high, and the method is suitable for on-site direct detection on SF6 gas in electrical equipment.

The invention provides an immunomagnetic bead used for capturing a leukocyte and a preparation method thereof. The immunomagnetic bead at least comprises a CD45 immunomagnetic bead and also can comprise or does not comprise one or two of a CD14 immunomagnetic bead and a CD15 immunomagnetic bead, wherein the CD45 immunomagnetic bead, the CD14 immunomagnetic bead and the CD15 immunomagnetic bead are immunomagnetic beads obtained by coupling a CD45 antibody, a CD14 antibody and a CD15 antibody with a magnetic sphere respectively; and a structural formula of the CD45 immunomagnetic bead, the CD14 immunomagnetic bead and the CD15 immunomagnetic bead is A-NH-N=CH-B, wherein A is the magnetic sphere and B is an antibody, or A is the antibody and B is the magnetic sphere. The immunomagnetic bead provided by the invention can be used for capturing the leukocyte, is good in specificity and sensitivity and is rapid in magnetic response, short in enrichment time and high in capturing efficiency; and the preparation method is simple, so that the immunomagnetic bead has strong practicability.

The invention discloses a method for preparing an anionic colorimetric sensing cellulosic material. A titanium dioxide film is deposited on the surface of filter paper cellulose by taking natural cellulose fiber material as a matrix, and taking tetrabutyl titanate as a precursor by a surface sol-gel process; a fluoride ion colorimetric sensing cellulosic material is obtained by introducing a fluoride ion-sensitive ligand alizarin complexant molecule single layer in a self-assembly way; and fluoride ions in solution can be detected by infiltrating the material prepared by the invention in the aqueous solution of anions for a certain period of time simply, and observing the color change of the material. The anionic colorimetric sensing cellulosic material prepared by the invention has the advantages of high sensitivity and selectivity to the fluoride ions, abundant material sources, low cost, simple preparation method and simple, rapid and economic fluoride oil detection.

Fabrication of an inertial sensor comprising at least one measurement beam (23) and an active body formed of a proof body (13) and of deformable blades (14), said active body being maintained in suspension inside a hermetic enclosure via its blades (14), the measurement beam (23) linking a part of the proof body (13) to an internal wall of said enclosure, said measurement beam (23) exhibiting a thickness less than that of the proof body (13).

The invention discloses a preparation method and application of ZnO/ZnFe2O4 nano-composites. According to the invention, a precipitation method is adopted to prepare a precursor material, and then the precursor material is calcined at high temperature to obtain the ZnO/ZnFe2O4 nano-composites. The preparation method of the ZnO/ZnFe2O4 nano-composites comprises the following steps: dropwise adding an aqueous solution of zinc chloride to an aqueous solution of potassium ferricyanide and a surfactant, stirring to react and standing for a period of time to form suspension liquid, cleaning and carrying out freeze drying to obtain a precursor sample; calcining a precursor at a certain temperature to prepare the ZnO/ZnFe2O4 nanocomposites. The preparation method provided by the invention is simple, green, pollution-free and high in practical level, and the obtained ZnO/ZnFe2O4 nano-composites can be directly used as gas sensitive materials.

The invention discloses a muscovy duck gosling plague latex particle agglutination reagent. The muscovy duck gosling plague latex particle agglutination reagent is characterized in preparation steps that: a GPV-resisting hybridoma cell strain D11 is used for preparing a GPV monoclonal antibody, and the GPV monoclonal antibody is used for preparing the muscovy duck gosling plague latex particle agglutination reagent; the GPV-resisting hybridoma cell strain D11 is preserved in CCTCC with a preservation date of April 15th, 2011 and a preservation number of C201120. The invention also discloses applications of latex particle agglutination (LPA) tests and latex particle agglutination inhibition (LPAI) tests established by using the muscovy duck gosling plague latex particle agglutination reagent in the determinations of goose parvovirus antigens, in the diagnosis of muscovy duck gosling plague, in serological investigation, and in immune antibody monitoring.

A device for real-time analysis of airborne chemical, biological and explosive substances has at least a gas analysis sensor, a fluorescence/luminescence sensor and a sensor for determining the particle size and number of particles. Each of the sensors is connected to a multireflection cell (multipass laser cell) as an open measurement path. In addition, the device also includes an evaluation unit for the real-time analysis of chemical, biological and explosive substances.

The invention provides a fluorescent quantitative reverse-transcription-polymerase chain reaction (RT-PCR) primer for detecting schmallenberg virus and a probe. The nucleotide sequences of the primer and the probe are as shown in SEQ ID No.1-3. The sensitivities of the primer and the probe provided by the invention can reach 10<-7> of a schmallenberg virus (SBV) ribose nucleic acid (RNA) standard substance; and moreover, the primer and the probe do not have amplification signals on detection samples without schmallenberg virus, so that the good specificities of the primer and the probe are shown.

The invention discloses a ZnCo2O4/ZnO heterostructure composite gas-sensitive material and a preparation method. The ZnCo2O4/ZnO heterostructure composite gas-sensitive material is formed by compounding flaky zinc oxide and zinc cobaltate, wherein the mass percent of the zinc oxide is 4-13.6%. Through change of the addition amounts of Zn(CH3COO)2.2H2O and Co(CH3COO)2.4H2O, the ZnCo2O4/ZnO heterostructure composite gas-sensitive materials with different ZnO contents are synthesized, which means that ZnO with different doping ratios can be synthesized by controlling the molar ratio of Zn to Co;the prepared ZnCo2O4/ZnO heterostructure composite gas-sensitive material has good sensitivity to triethylamine and has a wide application prospect in production of a novel efficient gas sensor.

Systems and methods for producing background-reduced fluorescence imaging signals include an illumination system that provides illumination light from an illumination source to a targeted area on the sample platform, a sensor adapted to detect light and having an array of sensing locations, and collection optics arranged and configured to project light emanating from the sample platform onto the sensor. In typical operation, light from the targeted area is projected onto a first portion of the sensor comprising a first plurality of the sensing locations and light from proximal to the targeted area on the platform is projected onto a second portion of the sensor comprising a second plurality of the sensing locations, and a second signal detected by the second portion of the sensor is subtracted from a first signal detected by the first portion of the sensor to produce a background-reduced signal, e.g., a signal with reduced background related noise.

The invention relates to the field of water quality detection, and in particular relates to a tracing method of biological pollution of a water body. The method comprises the following steps: determining characteristic microorganisms in target water body pollutants; selecting specific gene fragments of the characteristic microorganisms; and quantitating pollution sources and pollution conditions of the target water body through the specific gene fragments. According to the method provided by the invention, the characteristic microorganisms in the target water body pollutants are determined; then the pollution sources and the pollution conditions of the target water body are quantitated through the specific gene fragments of the characteristic microorganisms, so that the detection of a pollution level is improved to a molecular level. Thus, the high accuracy and the good sensitivity are realized; the target pollution sources are positioned well. Therefore, the sources of feces are accurately positioned and the pollution contribution rate of the water body is quantitated. As a result, a certain guiding significance in the objective evaluation of the aquaculture pollution contribution rate and the treatment of the pollution of the water body in a manner of adjusting measures to local conditions is provided.

The invention relates to a method for detecting EDTA (ethylene diamine tetraacetic acid) in a laundry detergent. The method comprises steps as follows: (1) preparing a potassium bicarbonate aqueous solution; (2) adding the to-be-detected laundry detergent to the potassium bicarbonate aqueous solution, stirring the solution at the temperature of 45-50 DEG C for 10-20 min, filtering the solution while the solution is hot, and naturally cooling the solution to the room temperature to obtain a pretreated solution; (3) adding an iron liquid to the pretreated solution, performing oscillating extraction and then centrifugation, and removing an aqueous phase to obtain an ion liquid phase; (4) adding trivalent iron salt to the ion liquid phase, after full and even mixing, performing chromatography separation with a gel column chromatography Superose 12 column, performing washing with n-hexane firstly, then performing gradient elution with a petroleum ether-normal propyl alcohol mixed solvent serving as an eluent, and collecting the eluent; (5) evaporation the solvent of the eluent until the solvent is almost dry, and performing dissolution, volume determination and filtration with an organic membrane to obtain a detection sample; (6) performing liquid chromatography separation on the to-be-detected sample to determine the content. The method is excellent in EDTA quantitation accuracy, and a new detection means is provided for control on the content of the EDTA in the laundry detergent.

The invention relates to the field of medical tumor marker detection, in particular to preparation of two antibody and antigen conjugates respectively from 1,1'-ferrocenediacetic acid/gold@platinum and thionine/gold@ platinum and a method thereof for simultaneously performing specificity detection on alpha-fetoprotein and carcinoembryonic antigen. The 1,1'-ferrocenediacetic acid/gold@platinum and thionine/gold@ platinum are respectively used for preparing the two kinds of antibody and antigen conjugates; according to the method for simultaneously detecting the alpha-fetoprotein AFP and the carcinoembryonic antigen CEA by an electrochemical sensor to be built, a modified glassy carbon electrode is put into a mixed solution of the alpha-fetoprotein and the carcinoembryonic antigen; then, active sites which are not subjected to specific binding are sealed; after the glassy carbon electrode is taken out, alpha-fetoprotein antigen and carcinoembryonic antigen mixtures with different concentrations are sequentially used for modifying the glassy carbon electrode, so that the antigen and the antibody realize the specific bonding; a sandwich immunosensor is built; the sandwich immunosensor is used for detecting the concentration of the alpha-fetoprotein and carcinoembryonic antigen by using a DPV (differential pulse voltammetry) method.

A resistive environmental sensor including an electrode stack and a sensing layer is provided. The electrode stack includes a first electrode layer, a second electrode layer, and a dielectric layer disposed between the first and second electrode layers, wherein the electrode stack includes a side surface, and the first and second electrode layers are exposed on the side surface of the electrode stack. The sensing layer is disposed on the side surface of the electrode stack, and the sensing layer s in contact with the first and second electrode layers. An environmental variation is inspected by sensing a resistance variation of the sensing layer that is between the first and second electrode layers. The above-mentioned sensor is capable of sensing gases, light, humidity, temperature, and so on. The above-mentioned sensor has advantages of low resistivity and good sensitivity.

The invention discloses rapid sex identification primers for trachinotus ovatus, which are primers P18-1, including a forward primer P18-1-F and a reverse primer P18-1-R, the base sequence of the forward primer P18-1-F is shown as SEQ ID NO: 1, and the base sequence of the reverse primer P18-1-R is shown as SEQ ID NO: 2. The invention also discloses a kit including the primers, a method of rapid sex identification for trachinotus ovatus by using the primers, and application of the primers, the kit and the method in rapid sex identification for trachinotus ovatus. The primers have good specificity, good sensitivity and high accuracy, the identification success rate is as high as 97%, and compared with a capillary electrophoresis identification method, the method does not require complicatedequipment, shortens the detection period, and reduces the detection cost.

The invention discloses a use of an SNP site of an FoxH1 gene. The use means an application of the SNP site rs750472 of the FoxH1 gene in the preparation of a congenital heart disease susceptibility diagnosis kit. The detection kit has a good sensitivity, stability and specificity. The kit has effective risk early-warning and early-stage diagnosis effects when the kit is used for the congenital heart disease susceptibility screening of fetuses in abdominal cavities of pregnant women.