5 results about "Automated microscopy" patented technology

The invention relates to the technical field of microscopic detection, in particular to a microscopic imaging system with bright field imaging and phase difference imaging, which comprises an imaging module, a bright field imaging illumination module, a focusing module, a phase difference imaging illumination light source module and a control module. The problems that in the prior art, the switching time is long, the definition degree of images is prone to being affected in the switching process, the target form of bright field image and phase difference image shooting is changed, and result contrastive analysis is not facilitated are solved.

This invention relates to the field of intelligent microscopic imaging technology, and more particularly to a workflow-driven microscopic imaging method and system based on visual programming. The method includes: S10, acquiring a microscopic imaging workflow containing task nodes and flow control nodes; S20, organizing the microscopic imaging workflow using a node-based flow model to form an imaging task queue; S30, sending a first control command to an automated microscope module and an image acquisition module according to the imaging task queue to acquire microscopic images; S40, acquiring the image analysis results of the microscopic images and determining whether the image analysis results meet preset trigger conditions; if yes, proceed to step S50; if no, proceed to step S60; S50, issuing a corresponding second control command according to the trigger conditions; S60, repeating steps S30 to S50 until a preset termination condition is met. This invention enables automated closed-loop control of the microscopic imaging process.

In one general aspect, the invention features a single-use cartridge for use with an apparatus that includes an automated microscope for analyzing the sample that includes a capillary tube on the cartridge having an exposed end, a cover over the tube with a window at a predetermined position along the tube from the exposed end, with the predetermined position corresponding to a desired sample quantity, a source of diluent and / or stain, and one or more flow paths that connect the capillary tube and a source of diluent and / or stain to the imaging chamber for analysis by the automated microscope.

The embodiment of the utility model provides a remotely-controlled automatic microscope. The remotely-controlled automatic microscope comprises a microscope module and a control assembly electrically connected with the microscope module, the plane bottom light source is arranged in the XY mobile platform, the X-axis horizontal displacement module is arranged on one side of the XY mobile platform, the Y-axis horizontal displacement module is arranged on the other side of the XY mobile platform, and the X-axis horizontal displacement module and the Y-axis horizontal displacement module are vertically arranged; a Z-axis module is arranged at the top of the base column assembly; when the remotely-controlled automatic microscope is started, the control assembly controls or remotely controls the X-axis horizontal displacement module and the Y-axis horizontal displacement module so as to control the XY moving platform to move, and the control assembly controls or remotely controls the Z-axis module so as to control the three-dimensional microscope to move up and down. The control assembly controls or remotely controls the optical magnification adjusting device so as to control the magnification of the three-dimensional microscope.

This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting blood cells in biological samples. A small unmeasured quantity of a biological sample such as whole blood is placed in the disposable test cartridge which is then inserted into the cell analyzer. The analyzer isolates a precise volume of the biological sample, mixes it with self-contained reagents and transfers the entire volume to an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping, when it is transferred into the imaging chamber. Images of essentially all of the cellular components within the imaging chamber are analyzed to obtain counts per unit volume. The devices, apparatus and methods described may be used to analyze a small quantity of whole blood to obtain counts per unit volume of red blood cells, white blood cells, including sub-groups of white cells, platelets and measurements related to these bodies.