3 results about "Y chromosome" patented technology

A sex chromosome typing method and apparatus, a device, a medium, and a product. The method comprises: first, on the basis of a Y chromosome concentration of a nucleic acid sample to be tested in a cfDNA sample to be tested, determining whether the nucleic acid sample to be tested carries a Y chromosome; in a branch of not carrying a Y chromosome, on the basis of an X chromosome concentration and an X chromosome concentration range, determining a sex chromosome type of the nucleic acid sample to be tested; and in a branch of carrying a Y chromosome, using the ratio of the X chromosome concentration to the Y chromosome concentration as a concentration ratio to be tested, and, on the basis of the concentration ratio to be tested and Cauchy distribution functions respectively corresponding to at least two preset sex chromosome types, determining the sex chromosome type of the nucleic acid sample to be tested, thereby solving the problem that conventional typing methods rely on a sample set, and reducing testing costs and maintenance costs while ensuring the accuracy of sex chromosome typing.

This invention belongs to the field of plant sex identification technology, and particularly relates to the application of a molecular marker in identifying the sex of *Zephyranthes* plants. The molecular marker is linked to the Y chromosome of *Zephyranthes* plants and comprises a sequence having at least 80%, 85%, 90%, 95%, 96%, 97%, 98%, 99%, or 100% sequence identity with SEQ ID NO:1. The molecular marker provided by this invention can be tightly linked to the Y chromosome of *Zephyranthes* plants, thereby achieving the purpose of early and rapid sex detection. This has significant practical implications for sex selection and proportioning of ornamental garden plants, understanding and protecting endangered *Zephyranthes* germplasm resources, and improving the effectiveness of ex-situ and in-situ conservation management.

This application discloses a method, device, equipment, and medium for sex chromosome detection based on a vector space projection model, relating to the fields of bioinformatics and gene detection. The method includes: aligning high-throughput sequencing data of the sample to be tested to a reference genome for copy number analysis to obtain the overall copy number of the X and Y chromosomes; if there is an abnormality in the overall copy number of the X / Y chromosome, mapping the sample to be tested to a position point in a two-dimensional vector space based on the overall copy number of the X and Y chromosomes, and calculating the perpendicular distances from the sample to the multiple reference evolution vectors in the two-dimensional vector space, taking the sex chromosome variation path represented by the reference evolution vector with the smallest distance as the sex chromosome variation path of the sample to be tested; comparing and analyzing the overall copy number of the X / Y chromosome with the judgment threshold corresponding to the sex chromosome variation path, and outputting the sex chromosome variation detection result.