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5results about How to "Comprehensive coverage" patented technology

Method and system for automatic identification of lipid double bond position based on ozone dissociation mass spectrometry data

PendingCN122090995AMeet analysis needscomprehensive coverage
This invention discloses an automatic identification method and system for lipid double bond positions based on ozone dissociation mass spectrometry data. The method includes: S1 constructing an in-silico ozone lipid fragment database; S2 preprocessing the raw mass spectrometry data and screening to obtain candidate features and auxiliary features; S3 retrieving ozone fragment features from the auxiliary features based on retention time and mass difference constraints; S4 constructing a directed bipartite graph of candidate features and fragment features; S5 scoring edges through multi-dimensional similarity calculation and removing redundancy by attribute combination; S6 comprehensively scoring the candidate lipid structures and outputting the double bond position identification results. This invention achieves high-throughput, low-false-positive automatic identification of double bond positions in multiple lipids and large-scale lipids through broad database coverage, multi-dimensional matching scoring, and redundancy removal strategies. It has strong structural resolution, is compatible with common mass spectrometry data formats, can be integrated with standard workflows, and is suitable for structural lipidomics research.
Owner:XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

A method for identifying gene duplication and functional differentiation in Rosaceae genera.

ActiveCN116612812BComprehensive coverageBiotechnologyBiological organism
This invention belongs to the fields of bioinformatics and molecular biology, specifically relating to a method for identifying gene duplication and functional differentiation in Rosaceae genera. By analyzing MAPK family proteins in rose and Arabidopsis thaliana, the invention identifies HT1, ANP3, Raf42, and Raf24 proteins that are duplicated and functionally differentiated in rose. Further application of bioinformatics and molecular biology techniques to Rosaceae plants reveals that only ANP3 exhibits duplication and functional differentiation in all Rosaceae plants. This invention provides a molecular-level reference for exploring the function of the MAPK family and the functional differentiation among ANP3-like genes in Rosaceae, laying the foundation for future research and identification of other duplicated and functionally differentiated genes in Rosaceae.
Owner:SHENYANG AGRI UNIV

Gene detection panel for detecting hemangioma and vascular malformation and application thereof

The invention belongs to the field of biological detection, and discloses a gene detection panel for detecting hemangioma and vascular malformation and application of the gene detection panel. The invention discloses a gene detection panel for hemangioma and vascular malformation. Comprising the gene detection panel and is used for detecting hemangioma and vascular malformation; an application of the gene detection panel in preparation of a hemangioma and vascular malformation diagnostic reagent or diagnostic kit; the gene detection panel is applied to a device for auxiliary diagnosis of etiology of hemangioma and vascular malformation patients; and the device is used for auxiliary diagnosis of pathogenesis of hemangioma and vascular malformation patients. The gene detection panel disclosed by the invention can efficiently and accurately identify gene mutation related to hemangioma and vascular deformity, can cover wide genes related to hereditary and sporadic vascular deformity, and can provide accurate information for diagnosis, treatment and prognosis evaluation of diseases.
Owner:PEOPLES HOSPITAL OF HENAN PROV

Elevator car convenient to maintain

The utility model discloses an elevator car convenient to maintain, which belongs to the technical field of elevator car maintenance, and is characterized in that the elevator car comprises an elevator car body and a plurality of keys, the right side of the inner wall of the elevator car body is fixedly connected with a sliding rail, and the front sides of the keys are provided with a sliding wiping mechanism; a spraying mechanism is arranged at the bottom of the wiping mechanism; the elevator car key solves the problems that part of existing elevator car keys are mostly designed in a protruding mode, particularly in crowded places such as hospitals, schools and markets, the surfaces of the keys become potential media for cross propagation of bacteria and viruses, and when workers clean elevator car keys in different areas of public places on a large scale, the keys cannot be damaged. The problems that a worker needs to hold disinfectant and cleaning cloth by hand to spray the disinfectant and then wipe the cleaning cloth, cross-regional pollution is possibly caused if the cleaning cloth or a disinfection tool is not replaced in time, the worker is prone to making contact with more bacteria, and the body health of the worker is threatened to a certain degree are solved.
Owner:CHENGDU JINYE TIANCHENG INTELLIGENT TECH CO LTD