17 results about "Nitroso Compounds" patented technology

This invention relates to the field of organic synthesis technology, specifically to a method for preparing aryltriazene; comprising the following steps: (1) preparing an aromatic nitroso compound Ar 1 NO is dissolved in the first solvent in the first ratio to obtain solution A; (2) unsymmetrical disubstituted hydrazine R 1 R 2 NNH2 is dissolved in the second solvent in the second ratio to obtain solution B; (3) under stirring, solution A and solution B are mixed and subjected to dehydration condensation reaction for 1-4 hours, and the reaction temperature of dehydration condensation is 10-40℃; after the reaction is completed, aromatic triazine is obtained by separation and purification; the first solvent and the second solvent are aprotic solvents; Ar 1 It is any of the substituted or unsubstituted phenyl, heterocyclic aryl, and fused-ring aryl groups, and the substituents on the ring do not react with hydrazine; R 1 R 2 It is at least one of alkyl and aryl groups. This preparation method is simple to synthesize, produces no unstable diazonium salt intermediates, has mild reaction conditions, and a relatively fast reaction rate.

The invention relates to the technical field of flocking adhesives, in particular to a high-performance single-component flocking adhesive and a preparation method thereof.The high-performance single-component flocking adhesive is at least prepared from, by mass, 40-60% of blocked polyurethane, 5-15% of phenol novolac epoxy resin, 0-5% of aromatic nitroso compounds, 0-5% of imine compounds and the balance solvent, the closed polyurethane has an oxime carbamate structure, the weight-average molecular weight is 60000-90000, by optimizing a product formula system, the problems of poor wear resistance, poor solvent resistance and the like after an adhesive is coated are effectively solved, meanwhile, the operation is convenient and fast, the efficiency is high, the application scene and the application range of the adhesive are expanded, and the market demand is better met.

To provide a method for reducing the generation of nitroso compounds in a drug raw material or a drug.SOLUTION: This method includes the following step A and / or B. Step A: a step for removing at least a portion of nitrogen oxides in an atmosphere that comes into contact with the drug raw material or the drug. Step B: a step for producing and / or storing the drug raw material or the drug under an atmosphere where the content of the nitrogen oxides is 50 ppb or less.SELECTED DRAWING: Figure 3

This application provides a quantitative method for the derivatization of nitrogen nitrosamines and its application. Through simple derivatization, nitrogen nitrosamines with different structures can be determined. In the embodiments of this application, the sample derivatization method is studied, and optimal reaction conditions for nitrogen nitrosamines are proposed. This application establishes a simple and sensitive liquid chromatography quantitative analysis method, successfully establishing a method for the derivatization analysis of nitrogen nitrosamines with different structures. This method has high selectivity, sensitivity, and accuracy, and is suitable for the accurate determination of nitrogen nitrosamines in complex samples and complex structures.

A photosensitive resin composition comprising (A) an alkali-soluble polymer, (B) a compound having an ethylenically unsaturated bond, (C) a photoinitiator, (D) a sensitizer, and (E) polymerization inhibitors, wherein (C) the photoinitiator includes one or more selected from a 2,4,5-triallyl imidazole dimer and an acridine compound, the contained amount of (C) the photoinitiator is 5.0 mass% or more with respect to the total mass of solid content of the photosensitive resin composition, (D) the sensitizer contains a specific compound represented by the compound described by formula (D1-1), and (E) the polymerization inhibitors include (E1) a first polymerization inhibitor selected from nitroso compounds and nitroxyl radicals and (E2) a second polymerization inhibitor other than the first polymerization inhibitor.

Disclosed herein are materials, articles of manufacture, and methods for reducing, mitigating, or precluding formation of and / or amount of a nitrosating agent and / or an N-nitroso compound, including an N-nitrosamine, from a packaging containing an active agent and a pharmaceutical dosage form in an enclosure, wherein the active agent is effective to reduce mitigate or preclude the formation and / or amount of a nitrosating agent and / or N-nitroso compound in the enclosure and / or in the pharmaceutical dosage form. Provided are drug delivery systems comprising a blister pack configured to house multiple pharmaceutical dosage forms, the blister pack comprising an active ingredient that is effective to reduce, mitigate or preclude the formation and / or amount of a nitrosating agent and / or N-nitroso compound in an enclosure of the blister pack and / or in the pharmaceutical dosage form.

The invention belongs to the field of metal bonding, and particularly relates to an adhesive composition for bonding baking-resistant rubber and metal and a preparation method of the adhesive composition. The adhesive composition is prepared from the following raw materials: modified halogen sulforubber, a nitroso compound cross-linking agent, an acid-binding agent, an adhesion accelerant and a dispersing agent, the preparation method comprises the following steps: firstly grinding and mixing the nitroso compound cross-linking agent, the accelerant, the dispersing agent and the like to prepare mother liquor, and then mixing with the modified halogen sulforubber and the like. The adhesive composition still keeps activity at 160-200 DEG C, is suitable for various elastomers, and is resistant to high-temperature fluid, resistant to corrosion and high in process adaptability.

The application discloses an organic boron reagent alpha-boryl oxime compound and a preparation method and application thereof, and belongs to the technical field of organic synthesis. N The alpha-boryl oxime compound is prepared by reacting a heterocyclic carbene borane adduct and a nitroso compound in an organic solvent. N The alpha-boryl oxime compound is prepared by simultaneously introducing an oxime group and a boron group functional group into both ends of the olefin with high selectivity through the boro-oximation reaction of the heterocyclic carbene borane, the nitrosamine compound and the olefin. The reaction avoids the use of a photosensitizer and a transition metal, has very good functional group tolerance and substrate universality, and also has good chemical selectivity, regioselectivity and stereoselectivity; the product alpha-boryl oxime compound can be efficiently used to synthesize various useful compounds through simple conversion, the types of the organic boron reagent are expanded, and the application prospect is good.

This application relates to the field of lithium-ion battery solid electrolyte material preparation technology, and particularly to a LATP solid electrolyte material with high stability to lithium metal anode and its preparation method. The material includes an LATP matrix; an organic coating layer covering the surface of the LATP matrix, wherein the organic coating layer is a bonding layer formed by grafting an organic coating layer with oxidizing functional groups onto a coupling agent, the thickness of which is 3-50 nm, accounting for 0.3%-5% of the total mass of the LATP solid electrolyte material. The organic compounds with oxidizing functional groups are selected from nitro compounds, nitroso compounds, or N-oxides. These functional groups inhibit the reduction of titanium ions in LATP through reversible redox reactions, significantly improving the interfacial stability between LATP and the lithium metal anode. The material preparation method of this application is simple, low-cost, and can effectively extend the cycle life of lithium metal batteries.

The present invention provides a pharmaceutical product containing sitagliptin or a salt thereof, wherein the generation of nitroso compounds derived from sitagliptin or a salt thereof is reduced. [Solution] A pharmaceutical according to one aspect of the present invention is a pharmaceutical containing sitagliptin or a salt thereof. This pharmaceutical has a water content of 2.8% by weight or less as measured by the Karl Fischer method, and a content of nitroso compounds derived from sitagliptin or a salt thereof of 1.0 ppm or less.

The invention relates to the field of effective and economical conversion of nitro or nitroso compounds in to corresponding amines. More it discloses a reduction processes of nitro or nitroso compounds to corresponding amino compounds, which exhibit differential solubility, exemplified & not restricted to the processes discussed for m-aminoacetophenone, the intermediate of Phenylephrine, ethyl3- [[4-(methylamino)-3-aminobenzoyl](pyridin2yl)amino]propanoate the intermediate of Dabigatran, and 2,4-Difluoroaniline the intermediate of Pantoprazole. Even more particularly, the invention relates to a process involving use of minimal quantity of water or quantity of water required only as the source of hydrogen for generation of sufficient reduction potential to perform the chemical reaction. The process offers a. safer, cost competitive and greener alternative to the conventional process of reduction. A key benefit of the invention is that it avoids side product / s & / or impurity / s resulting from usage of large quantity of water especially when other sensitive / reactive groups are present in the molecule.

The invention relates to the technical field of photovoltaic cells, in particular to a preparation method of a surface-strengthened silicon wafer substrate of a photovoltaic cell, which comprises the following steps of: texturing the silicon wafer substrate, and performing surface strengthening treatment twice to obtain the surface-strengthened silicon wafer substrate; the two times of surface strengthening treatment are specifically as follows: during the first time of surface strengthening treatment, an etching solution A is adopted to smooth the surface appearance defects of the silicon wafer substrate, and during the second time of surface strengthening treatment, an etching solution B is adopted to smooth the surface lattice defects of the silicon wafer substrate, the acidic etching solution as the etching solution B comprises hydrofluoric acid, an oxidizing agent and deionized water, and the oxidizing agent is one or a combination of more of a nitro compound and a nitroso compound. The method has the beneficial effects that through two times of surface strengthening treatment, the bending breaking strength of the silicon wafer substrate is improved, and the bending breaking strength of the crystalline silicon photovoltaic cell is finally improved; the method can be completed without special equipment, and has the advantages of being low in production cost and suitable for large-scale production.

The application relates to the technical field of secondary batteries, and particularly discloses an additive for a positive electrode electrolyte, an electrolyte containing the same and application. The positive electrode electrolyte contains an electrolyte lithium salt, an organic solvent and an additive, the organic solvent is a carbonate solvent, and the additive is a nitrite or a nitroso compound. The electrolyte can be applied to a lithium ion battery or a lithium metal battery, and the electrolyte of the application can react on the surface of the positive electrode to generate an inorganic fast-ion solid-state electrolyte protection film rich in lithium nitrogen oxides, accelerate the transmission of lithium ions in the solid-state electrolyte film, and further improve the rate performance and cycle stability of the lithium ion battery.

The application discloses an ultra-high performance offshore wind power grouting material and a preparation method and application thereof. According to weight parts, the ultra-high performance offshore wind power grouting material comprises the following components: cement 600-800 parts, viscosity reducer 100-200 parts, silica fume 75-150 parts, ground zeolite powder 75-150 parts, water reducing agent 6-8 parts, defoaming agent 1-2 parts, plastic expansion agent 0.1-0.5 parts, anti-cracking agent 50-80 parts, carborundum 700-900 parts and water 155-170 parts; the cement is 52.5-grade white portland cement; the viscosity reducer is composed of microbeads, limestone powder, ultra-fine mineral powder and metakaolin, wherein the microbeads account for 30wt%-50wt%, the limestone powder accounts for 15wt%-35wt%, the ultra-fine mineral powder accounts for 20wt%-30wt% and the metakaolin accounts for 5wt%-15wt%; the plastic expansion agent is composed of an azo compound plastic expansion agent and a nitroso compound plastic expansion agent with a weight ratio of (0.5-2):1. The ultra-high performance offshore wind power grouting material has high early strength, good fluidity, excellent durability and micro-expansion characteristics, and has the advantages of simple preparation process and low cost.

The invention relates to an anti-wear high-activity metal rubber heat vulcanization adhesive and a preparation method thereof, and relates to the technical field of adhesive preparation, and the adhesive comprises film-forming resin, a nitroso compound, a special high-activity vulcanizing agent, a special reactive coupling agent, a reinforcing filler, an acid acceptor and a solvent. The anti-wear high-activity metal rubber heat vulcanization adhesive provided by the invention has excellent bonding strength on various rubber products which are difficult to bond, such as natural rubber products containing reclaimed rubber, low-compression permanent deformation rubber products, high-hardness rubber products, low-hardness rubber products, rubber products with high oil filling content and the like.

The application relates to the technical field of photovoltaic cells, in particular to a preparation method of a surface-strengthened silicon wafer substrate of a photovoltaic cell. After texturing of a silicon wafer substrate, twice surface-strengthening treatment is carried out to obtain a surface-strengthened silicon wafer substrate. The twice surface-strengthening treatment specifically comprises: in the first surface-strengthening treatment, etching solution A is used to round and smooth the surface morphology defects of the silicon wafer substrate; and in the second surface-strengthening treatment, etching solution B is used to smooth the surface lattice defects of the silicon wafer substrate. The acidic etching solution B comprises hydrofluoric acid, an oxidizing agent and deionized water, and the oxidizing agent is a combination of one or several of nitro compounds and nitroso compounds. The beneficial effect is that the twice surface-strengthening treatment improves the bending fracture strength of the silicon wafer substrate and finally improves the bending fracture strength of the crystalline silicon photovoltaic cell; the method can be completed without using special equipment, has the advantages of low production cost and suitability for large-scale production.

Disclosed herein are materials, articles of manufacture, and methods for decreasing, mitigating, removing or precluding formation of an amount of a nitrosating agent and / or an N-nitroso compound, including an N-nitrosamine, in an enclosure of a pharmaceutical drug package to inhibit a potential adverse health effect on a patient associated with the nitrosating agent or N-nitroso compound. The package contains an active agent and a pharmaceutical dosage form in an enclosure of the package. The active agent is effective to decrease, mitigate, remove or preclude the formation of an amount of the nitrosating agent and / or N-nitroso compound in the enclosure and / or in the pharmaceutical dosage form. Also provided are drug delivery systems including a blister pack configured to house multiple pharmaceutical dosage forms, the blister pack including an active agent as discussed above.