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7results about How to "Toxic" patented technology

Chicken infectious anemia virus, chicken infectious anemia virus egg yolk antibody and preparation method and application thereof

The invention relates to the technical field of bioengineering, and particularly discloses a chicken infectious anemia virus, a chicken infectious anemia virus egg yolk antibody and a preparation method and application thereof. The invention relates to a chicken infectious anemia virus, which is preserved in the China General Microbiological Culture Collection Center (CGMCC), and is named as the chicken infectious anemia virus RD240101A, the preservation date is September 23, 2024, and the preservation number is CGMCC NO.46198. The chicken infectious anemia virus has the advantages that the chicken infectious anemia virus is named as the chicken infectious anemia virus RD240101A; the chicken infectious anemia virus egg yolk antibody is prepared by taking an inactivated vaccine prepared from the chicken infectious anemia virus RD240101A as an immunogen, is high in specificity and good in safety, does not have any local or whole-body adverse reaction caused by injection of the antibody after being inoculated to chicks, can provide effective immune protection for chicken flocks, and can be used for preparing the chicken infectious anemia virus egg yolk antibody. And the method has a good commercial development prospect.
Owner:QINGDAO RUNDA BIOTECH

Automatic sealing and blanking device for vertical externally heated sintering furnace

The utility model relates to the technical field of roasting furnace, concretely is a vertical additional temperature roasting furnace automatic sealing material dropping device, including the material dropping box, the material dropping box top is provided with the material dropping pipe connected with the roasting furnace discharge gate, the material dropping box inside is installed with the conveyer belt, the conveyer belt is driven through drive motor, the conveyer belt is opened with the air hole, and is located conveyer belt bottom and is provided with cooling fan, the cooling fan is used for the material cooling on conveyer belt through air hole, be provided with gravity filling machine on the material dropping box, the feed inlet of gravity filling machine is located the discharge end of conveyer belt, the gravity filling machine bottom is provided with sealing machine. The utility model has the advantage that the processed material is directly packed, solves the existing roasting furnace discharge and the transportation process, the material is easy to be damp and contact with external material, leads to the metamorphic problem of problem.
Owner:YUNXI JIUFENG VANADIUM INVESTMENT CO LTD

Purging, sampling and discharging integrated sampling valve capable of preventing leakage and convenient to puncture

The utility model relates to the technical field of sampling valves, in particular to an anti-leakage convenient-to-puncture purging, sampling and discharging integrated sampling valve which comprises a sampling valve body, a sampling needle suite is detachably arranged at the lower end of the sampling valve body, the sampling needle suite comprises a clamping sleeve nut, a front clamping sleeve, a rear clamping sleeve and a sampling needle assembly, and the sampling needle assembly comprises a flow guide seat. A sampling needle and a purging needle are fixedly and hermetically connected to the bottom end of the flow guide seat, a flow guide hole is formed in the center of the top end of the flow guide seat and connected with a sampling inclined hole, the sampling inclined hole is connected with the sampling needle, a purging hole is formed in the side face of the flow guide seat and connected with the purging needle, and the flow guide seat is sleeved with the front clamping sleeve and the rear clamping sleeve. The clamping sleeve nut is in threaded connection with a sampling port in the lower end of the sampling valve body, and the bottom face of the inner side of the sampling nut makes contact with the bottom face of the rear clamping sleeve. The sampling needle provided by the utility model adopts all-metal sealing, so that leakage caused by aging or fracture of rubber is avoided.
Owner:WANLUOKE FLUID TECHNOLOGY (JIANGSU) CO LTD

Methods of preparing drug eluting microsphere suspensions, drug eluting microsphere suspensions, and uses thereof

PendingCN122272869AReduce severe postoperative painReduce severe painDrugs solutionTumor response
This invention relates to the field of biomedical technology, providing a method for preparing a drug-eluting microsphere suspension, the drug-eluting microsphere suspension, and its applications. The method includes: S1. Removing the storage solution from the drug-eluting microspheres to obtain a microsphere precipitate; S2. Adding a chemotherapy drug solution to the microsphere precipitate to load the drug into the microspheres; S3. Mixing physiological saline and a non-ionic contrast agent at a volume ratio of 1.5:1 to prepare a dilution medium; S4. Adding the dilution medium prepared in step S3 to the microspheres after drug loading in step S2, so that the total suspension volume reaches a preset multiple of the microsphere precipitate volume, obtaining a microsphere suspension; S5. Shaking the microsphere suspension obtained in step S4 to mix thoroughly. This invention significantly reduces postoperative chemical stimulation pain by increasing the dilution factor of the drug-eluting microsphere suspension, while unexpectedly improving tumor response, achieving a synergistic effect of pain reduction and efficacy enhancement.
Owner:TIANJIN CITY THIRD CENT HOSPITAL

An underwater structure settlement non-destructive intelligent monitoring optical fiber arrangement method

PendingCN122815637AOvercoming the pitfalls of inferred settlementavoid damage
The application discloses a kind of based on underwater structure settlement nondestructive intelligent monitoring optical fiber layout method, comprising the following steps: optical fiber layout is carried out on dry canal bottom surface and slope surface;Adopt negative pressure suction disc assembly and fix optical fiber on canal bottom concrete slab;When disassembling, pressurized grouting is added through communicating pipe, and biological-based adhesive strip is expanded, the negative pressure adsorption state is destroyed, and the negative pressure suction disc assembly is removed.The application can obtain canal bottom settlement data in real time before, during and in the operation period of crossing engineering construction by laying optical fiber on dry canal bottom surface and slope surface and fixing optical fiber on concrete slab by negative pressure suction disc assembly, provides direct basis for judging the influence of crossing engineering on dry canal deformation, and does not need to punch or anchor in concrete bottom plate, completely avoids damage to canal bottom structure, and will not cause any pollution to dry canal water, meets the high protection level requirement of South-to-North Water Diversion Project.
Owner:NORTH CHINA UNIV OF WATER RESOURCES & ELECTRIC POWER

siRNAs that inhibit IL-25 gene expression and their applications

ActiveCN116024212BIncreased resistance to enzymatic hydrolysisToxicOrganic active ingredientsImmunological disordersImmunologic disordersAutoimmune condition
This invention discloses an siRNA that inhibits IL-25 gene expression and its application. The siRNA sequence provided by this invention can specifically knock down IL-25 expression levels. Furthermore, by modifying the sense strand with thiocyanate, this invention enhances the ability of siRNA to resist enzymatic hydrolysis in serum and prolongs its duration of action without significantly increasing cytotoxicity, thus bringing important application value to the treatment of autoimmune diseases.
Owner:SILICON GENE TECH (SHANGHAI) CO LTD

Mesophase pitch and preparation method thereof

The invention belongs to the technical field of petroleum deep processing technology and carbon mesophase material research, particularly relates to mesophase pitch, and further discloses a preparation method of the mesophase pitch. According to the preparation method of the mesophase pitch, on the basis of a traditional catalytic cracking (FCC) oil slurry synthesis process, catalytic cracking (FCC) oil slurry is taken as a raw material, in the presence of a heteropoly acid ferric salt as a catalyst, a small amount of magnetic organic iron macromolecular complex is added, and the mesophase pitch is prepared by adopting a catalytic polycondensation method; and carrying out settling separation on the catalytic polycondensation product by using a low-intensity magnetic field assisted thermal settling process, and then carrying out quinoline extraction on the anisotropic asphalt at the lower layer to remove impurities such as ash and an iron catalyst in the asphalt, thereby obtaining the high-quality mesophase asphalt.
Owner:CHINA PETROLEUM & CHEMICAL CORP +1