366results about How to "Inhibition production" patented technology

A footwear system has a sole unit with a number of cavities formed between a midsole and an outsole. The cavities are complementary to one another to form groundward oriented air bulges in the outsole that are connected by a passage formed in the midsole. The passage permits movement of air between the cavities during use of the footwear system in a shoe.

A synergistic composition is provided for controlling odor from waste products. The composition comprises a combination of nitrate salt, sulfide-consuming compound, pH-elevating compound, sulfide-oxidizing, nitrate-reducing bacteria, and sulfide-oxidizing enzyme. The method includes adding a sufficient amount of the composition to a waste stream to provide sufficient sulfide-consuming compound to effect immediate removal of sulfide. The composition incorporates a pH elevating compound, which both decreases the amount of gaseous H2S and puts the aqueous phase into a pH range where naturally occurring bacteria can more easily metabolize the sulfide. The composition also includes one or more nitrate salts which will accomplish longer term prevention of odors. Specific bacteria are incorporated into the formulation to insure that the nitrate has the right type and amount of bacteria present to prevent formation of and / or consume sulfide. Specific enzymes are incorporated into the formulation to promote oxidation of sulfide.

This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the invention relates to aromatic guanylhydrazone (more properly termed amidinohydrazone) compositions and their use to inhibit the uptake of arginine by macrophages and / or its conversion to urea. These compositions and methods are also useful in preventing the generation of nitric oxide (NO) by cells, and so to prevent NO-mediated inflammation and other responses in persons in need of same. In another embodiment, the compounds can be used to inhibit arginine uptake in arginine-dependent tumors and infections.

Disclosed herein is a lid for airtight containers. The lid according to the present invention includes a plurality of locking flap handles, which are coupled to a lid body so as to be rotatable, and each of which has a locking protrusion to be locked to a locking depression formed in the outer edge of the upper end of a container body. The locking flap handles are connected to the lid body by respective film hinges. The film hinge includes an elastic hinge part, which is continuous with the upper surface of the lid without having a stepped portion and is curved outwards at a predetermined curvature, and a connection part, which connects the elastic hinge part to the locking flap handle. The connection part extends a predetermined length to disperse an impact generated when the locking flap handle is locked to the container body. Thus, when the locking flap handle is locked to the container body, the elastic hinge part is folded around an inner corner, which forms a boundary between the elastic hinge part and the lid body, and is elastically brought into contact with the outer surface of the lid body.

A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less than about 25, is useful as an NO donor. When the compound is obtained from a carbon acid with a pKa less than about 10, it provides vascular relaxing effect when used at micromolar concentrations and this activity is potentiated by glutathione to be obtained at nanomolar concentrations. When the compound is obtained from a carbon acid with a pKa ranging from about 15 to 20, vascular relaxing effect is obtained at nanomolar concentrations without glutathione. In another embodiment, a biocompatible polymer incorporates a C-nitroso moiety.

A lid for an airtight container has a rim part for sealing to the container and plural locking flap handles extending from the rim part and rotating between open and locked positions. Each handle has a locking protrusion for locking to the container in its locked position, and a film hinge with an outer surface that smoothly curves continuously into an upper surface of the rim part of the lid, in the open position of the handle. The film hinge has an elastic hinge part that extends by a predetermined length to disperse an impact generated when the handle is locked to the container and the elastic hinge part is folded as the handle is moved from its open to its locked position.

A synergistic composition is provided for controlling odor from waste products. The composition comprises a combination of nitrate salt, sulfide-consuming compound, pH-elevating compound, sulfide-oxidizing, nitrate-reducing bacteria, and sulfide-oxidizing enzyme. The method includes adding a sufficient amount of the composition to a waste stream to provide sufficient sulfide-consuming compound to effect immediate removal of sulfide. The composition incorporates a pH elevating compound, which both decreases the amount of gaseous H2S and puts the aqueous phase into a pH range where naturally occurring bacteria can more easily metabolize the sulfide. The composition also includes one or more nitrate salts which will accomplish longer term prevention of odors. Specific bacteria are incorporated into the formulation to insure that the nitrate has the right type and amount of bacteria present to prevent formation of and / or consume sulfide. Specific enzymes are incorporated into the formulation to promote oxidation of sulfide.

The present invention describes compositions and methods for treating, preventing and improving hyperpigmentation, or other unwanted pigmentation of the skin, or other unwanted skin condition, such as age spots, aged skin, skin discoloration, etc., wherein the compositions include siRNA-gene silencing oligomers specific for tyrosinase. The compositions are used to treat a broad variety of pigmentation conditions, and are preferably applied to the skin, or are delivered by directed means to a site in need thereof.

A method of selectively enhancing photothermal sebaceous gland disruption and treatment of acne is disclosed. The method provides for alleviation of the acne symptoms as well as preventing acne recurrence and new acne from occurring.

Cold storage solutions for the preservation of organs and biological tissues prior to implantation, including a prostaglandin having vasodilatory, membrane stabilizing, platelet aggregation prevention upon reperfusion, and complement activation inhibitory properties, a nitric oxide donor, and a glutathione-forming agent.

A diesel engine system includes a diesel engine, a throttle valve, an EGR (Exhaust Gas Recirculation) path, an EGR valve and a controller. The throttle valve controls a flow rate of intake air to the diesel engine. Exhaust gas is recirculated along the EGR path from an exhaust port to an intake port of the diesel engine. The EGR valve controls a flow rate of the exhaust gas. The controller controls the throttle valve and the EGR valve such that an opening of the throttle valve decreases and an opening of the EGR valve increases when a load of the diesel engine increases. The controller controls the EGR valve such that the opening of the EGR valve increases after the opening of the EGR valve is held constant for a first predetermined holding time.

A substrate cleaning apparatus is used to clean a substrate with a cleaning liquid. The substrate cleaning apparatus includes a substrate holding mechanism configured to hold a substrate horizontally, a rotating mechanism configured to rotate the substrate held by the substrate holding mechanism, a liquid supply nozzle for supplying a cleaning solution to the substrate, and a spin cover provided around the substrate and rotatable at substantially the same speed as the substrate. The spin cover has an inner circumferential surface shaped so as to surround the substrate. The inner circumferential surface is, from a lower end to an upper end thereof, inclined radially inwardly.