208 results about "Nonallergic rhinitis" patented technology

The present invention relates to anti-IL13 antibodies that bind specifically and with high affinity to both glycosylated and non-glycosylated human IL13, does not bind mouse IL13, and neutralize human IL13 activity at an approximate molar ratio of 1:2 (MAb:IL13). The invention also relates to the use of these antibodies in the treatment of IL13-mediated diseases, such as allergic disease, including asthma, allergic asthma, non-allergic (intrinsic) asthma, allergic rhinitis, atopic dermatitis, allergic conjunctivitis, eczema, urticaria, food allergies, chronic obstructive pulmonary disease, ulcerative colitis, RSV infection, uveitis, scleroderma, and osteoporosis.

Disclosed are methods of treating allergic conjunctivitis and allergic rhinitis in a subject that involve topically administering to the subject a composition comprising a pharmaceutically effective amount of an H1 antagonist and an anti-TNFα compound.

An implanted system for treating sinusitis or allergic rhinitis is provided, wherein the implanted system has a circumferentially extending wall formed of a biodegradable polymer, and the wall includes a plurality of interspaces, with biodegradable fiber bundles containing drugs interspersed in the interspaces. The implanted system formed of the biodegradable polymer can provide a sufficient normal force perpendicular to the external surface during a compression, and prevent the supported channel from being closed after the release in a location for the implantation (a location of pathological changes or ostium of the sinus). The implanted system formed of the biodegradable polymer has an axial internal bore to guarantee the aeration for the nasal cavity after the implantation. The implanted system formed of the biodegradable polymer can be naturally degraded in the nasal cavity. Compared with prior stents which cannot directly contact with certain locations of pathological changes, the biodegradable fiber bundles containing drugs carried on the implanted system can reach those locations of pathological changes to optimize the therapeutic effect.

The invention discloses the structure of four novel bakkenolide compounds extracted from Petasites tricholobus Franch. having a formula (1), the process for extraction and separation, and the use of the compounds in preparing medicament for the treatment and prevention of diseases possibly related to theramine and / or leukotrienes constituents, including asthma, allergic rhinitis, nasal sinusitis, conjunctivitis, food allergy, psoriasis, urticaria, pruritus, eczema, chronic infectious arthritis, enteropathy, nervous disease and otitis.

The invention discloses a rhinitis treatment medicine. The medicine is a medicinal composition prepared by carrying out certain technologies of raw materials comprising pure natural plants, animals and other materials. The medicine has the characteristics of carrying convenience, realization of use at all times and places, suitableness for inpatient adults and inpatient children, self operation for above six-year-old children, fast absorption, high bioavailability, high curative effects and no toxic side effects on acute and chronic rhinitis, nasosinusitis and allergic rhinitis through a large amount of clinical applications, and no recurrence after curing. The rhinitis treatment medicine has the advantages of wide sources of the used raw materials, low cost, simple preparation method, and no discharge of three wastes in the production process.

The present invention relates to a novel compound or a salt thereof, which is useful as a CRTH2 antagonist, especially as a medicament for disorder that participates eosinophil, for example, allergic disorder such as asthma, allergic rhinitis, allergic dermatitis, conjunctival inflammation, hives, eosinophilic bronchitis, food allergy, inflammation of the nasal sinuses, multiple sclerosis, angiitis, or chronic obstructive pulmonary disease (COPD) and the like.

The invention discloses a traditional Chinese medicine composition for treating allergic rhinitis, comprising the following crude medicines in parts by weight: 28-32 parts of honeysuckle, 28-32 parts of baical skullcap root, 28-32 parts of paniculate swallowwort root, 13-17 parts of xanthium, 13-17 parts of magnolia flower, 7-11 parts of asarum, 7-11 parts of mint, 13-17 parts of angelica, 13-17 parts of centipeda minima, 22-26 parts of chuanxiong rhizome and 16-20 parts of borneol. The preparation method comprises the steps of crushing all components, screening with a sieve of 200 meshes and mixing evenly. When used for treatment, the medicament provided by the invention is put into a medicine bag made of non-woven fabric, then the medicine bag is sown on the inner surface of a disposable mask, and a patient wears the mask and aligns the medicine bag with the nostrils. A course of treatment lasts for 5 days, and generally allergic rhinitis can be cured by two courses of treatment. The medicament provided by the invention is directly inhaled and has the advantages of quick effect taking, convenience in use, safety, reliability, no toxic side effect, low cost and the like.

The invention provides a medicament for treating allergic rhinitis, belonging to a medicament using traditional Chinese medicines as effective ingredients. The medicament for treating allergic rhinitis is prepared from the raw materials of milkvetch roots, small centipeda herbs, asarum, violet magnolia, cocklebur fruits, angelica roots, borneol, sesame oil and liquid paraffin. The medicament has good treatment effect, is convenient for use, overcomes the defects of long treatment course, great pain, high expense, more complications, easy relapse and the like of Western medicine treatment, and also overcomes the defects of slow effect taking, inconvenient use and the like of traditional Chinese pills, oral decoctions, patches and the like.

The invention provides Chinese medicinal snorted powder for preventing allergic rhinitis, which is prepared from the following Chinese medicinal materials by weight: 10-15 parts of as arum, 12-18 parts of Schizonepeta, 10-15 parts of radices sileris, 5-10 parts of notopterygium root, 5-10 parts of cocklebur fruit, 8-12 parts of rhizoma acori graminei, 8-12 parts of platycodon grandiflorum, 10-15 parts of ligusticum wallichii, 8-12 parts of radix angelicae, 5-10 parts of Semen Cuscutae, 10-15 parts of rhizoma cimicifugae, 5-12 parts of scutellaria baicalensis, 5-9 parts of liquorice, 5-12 parts of mint and 8-12 parts of violet magnolia. The fifteen Chinese medicinal materials are screened carefully, cut up, dried in the air and pulverized into Chinese medicinal snorted powder by a pulverizer, and then the Chinese medicinal snorted powder can be sterilized and bottled. The Chinese medicinal snorted powder for preventing allergic rhinitis is prepared by using a simple method and has the advantages of high medicine utilization ratio, quick acting and remarkable treatment effect.

A method and strip for treating allergen-induced airway inflammation. The method includes applying a nasal or skin strip containing a mixture of an allergen and a pharmaceutically acceptable carrier to an individual having allergen-induced airway inflammation in a manner consistent with local nasal immunotherapy.

The invention relates to a medicine for treating allergic rhinitis, which takes radix astragali, divaricate saposhnikovia root, atractylodes rhizome, grass leaf sweelflag rhizome, cocklebur fruit, angelica root, Chinese angelica, szechuan lovage rhizome, cassia twig, radix paeoniae alba, gizzard-membrane of chicken, large-leaved gentian, rhizoma atractylodis, amur corktree bark, tuckahoe, chrysanthemum and liquorice as raw materials; the raw materials are added with water and decocted to be concentrated into thick paste; after that, the thick paste is dried and ground, and then is filled intocapsules; finally, after being sterilized, the capsule product can be prepared. The medicine has the functions of warming lung and tonifying spleen, eliminating evils and activating organs as well asactivating blood circulation to dissipate blood stasis, is used for treating the allergic rhinitis with reliable, rapid and convenient treating effect, is safe to take, and has the total effective rate of 96.9% through clinical observation.

The invention discloses medicine for treating allergic rhinitis and a method for preparing the medicine. The medicine comprises, by weight, 16-20 parts of astragalus, 14-16 parts of fried fructus xanthii, 14-16 parts of flos magnoliae, 10-14 parts of bighead atractylodes rhizome, 8-12 parts of angelica dahurica, 10-14 parts of cicada slough, 6-10 parts of salvia miltiorrhiza, 6-10 parts of licorice, 11-13 parts of sucrose powder and 1-3 parts of dextrin which are manufactured into grains. The method includes extracting volatile oil, mixing raw materials; adding the raw materials into water and soaking the raw materials in the water; and decocting the raw materials in the water, and the like so as to obtain a finished product. The medicine and the method have the advantages that the medicine is granular preparation, can be taken conveniently, is portable, is low in cost and can realize effects of tonifying qi, strengthening exterior, dispelling coldness, eliminating pathogens, dredging channels and promoting blood circulation, symptoms such as nasal obstruction, rhinocnesmus, sneezing and rhinorrhoea caused by the allergic rhinitis can be effectively improved, a curative effect is persistent, and the total effective rate can reach 90% at least as shown by observation for clinical effects.

The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious rhinitis.

The invention relates to a Chinese medicament, in particular to a Chinese medicament for treating allergic rhinitis, which is a preferred Chinese medicament for treating the allergic rhinitis of various groups, and is prepared from the following raw materials in portion by weight: 10 to 30 portions of membranous milkvetch root, 5 to 25 portions of tangerine peel, 5 to 25 portions of divaricate saposhnikovia root, 5 to 25 portions of tatarian aster root, 10 to 30 portions of pinellia tuber and 5 to 15 portion of ginger. The Chinese medicament has scientific and reasonable formula, can stably control and treat the allergic rhinitis, defuses the allergy in modes of distinguishing a root cause and mediating and balancing, and has simple and convenient manufacture method, short treatment course, quick response, obvious effect, reliability and no toxic and side effects.

The invention discloses a Chinese medicinal composition for treating allergic rhinitis, which is prepared from the following raw materials: caulis perllae, great burdock achene, chrysanthemum, belvedere fruit, tribulus terrestris, almond, gypsum, siberian cocklour fruit, biond magnolia, simpleleaf shrub chastetree fruit, dark plum fruit, raw liquoric root, Chinese data and processed ephedra herb. The Chinese medicinal composition has the excellent effect of treating the allergic rhinitis.

The invention relates to a Chinese medicinal tea-substitution brewing potion for treating allergic rhinitis. The Chinese medicinal tea-substitution brewing potion is characterized by being mainly prepared from the following raw medicinal materials in weight part: 2-5 parts of ephedra, 1-3 part(s) of poria, 1-3 part(s) of monkshood, 2-5 parts of astragalus root, 2-5 parts of honeysuckle flower, 1-3 part(s) of licorice and 1-3 part(s) of jujube. The Chinese medicinal tea-substitution brewing potion is prepared by the following steps of: respectively cutting the raw medicinal materials into slices or thin segments and mixing the raw materials. 30-60g of the mixed raw materials is taken as a dose each time, is brewed by using boiled water for 20-40 minutes, then can be drunk, and can be continuously brewed by using the boiled water 5-8 times for drinking, and then, medicine dregs are thrown away. A patient can drink 1-2 dose(s) each day, and the disease can be remarkably or thoroughly treated by drinking for 1-3 dose(s). The Chinese medicinal tea-substitution brewing potion disclosed by the invention has the functions of benefiting defensive qi and strengthening exterior, detoxicating and promoting tissue generation, promoting eruption to relieve itching, and the like, and is used for treating the allergic rhinitis.

The present invention belongs to the technical field of traditional Chinese medicine, in particular to a medicine for remedying the allergic coryza, which solves the problem in the prior art that the medicine used for remedying the allergic coryza has bad curative effect. The medicine for remedying the allergic coryza is made from the following raw materials: milkvetch root, biond magnolia flower, Siberian cocklebur fruit, selfheal, stiff silkworm, baical skullcap root, earthworm, sharpleaf calargal seed, the root bark of peony tree, liquorice and Chinese date. The medicine of the present invention has the following beneficial effects of short treatment period, obvious curative effect, low treatment cost and not causing recrudescence easily.

The invention relates to a Chinese medicament for treating infantile allergic rhinitis. The Chinese medicament is characterized in that the Chinese medicament is prepared from the following raw materials by weight proportion: 2 to 10g of dahurian angelica root, magnolia flower, Szechuan lovage rhizome, divaricate saposhnikovia root, dry longan and spina date seed respectively, 4 to 14g of bighead atractylodes rhizome, Chinese angelica, white paeony root and prepared rhizome of rehmannia respectively, 13 to 23g of radix astragali, 10 to 20g of heterophylly falsestarwort root, 2 to 8g of villous amomum fruit, and 0.5 to 1.5g of asarum. The Chinese medicament is decocted by using water, is respectively taken once in the morning and evening per day, 7 to 10 days is a treatment period, and can cure the infantile allergic rhinitis after 2 to 3 treatment periods. The Chinese medicament is suitable for children under 10-year-old. The Chinese medicament has the advantages of convenient material acquirability, simple manufacture, economy and low cost, and is suitable for popularization and use.

The present invention relates to a medicine composite for preventing and curing allergic rhinitis and anaphylactic rhinitis. It is made up by using (by weight portion) 7-9 portions of astragalus root, 2-4 portions of bighead atractylodes rhizome, 2-4 portions of ledebouriella root, 2-4 portions of dahurian angelica root, 4-6 portions of ephedra, 2-4 portions of magnolia flower and 3-5 portions of tree peony bark. Said medicine composite can be made into capsule.

The invention relates to a drug for treating allergic rhinitis. The drug is prepared from the following active pharmaceutical ingredients in parts by weight: 8-15 parts of herba ephedrae, 8-15 parts of ramulus cinnamomi, 8-15 parts of radix paeoniae alba, 8-15 parts of rhizoma zingiberis, 5-10 parts of herba asari, 8-18 parts of processed rhizoma pinelliae, 8-18 parts of radix glycyrrhizae preparata, 8-15 parts of fructus schisandrae chinensis, 10-15 parts of radix bupleuri, 10-15 parts of codonopsis pilosula, 10-18 parts of radix saposhnikoviae, 10-15 parts of flos magnolia and 10-15 parts ofChinese dates. The drug provided by the invention has the efficacies of strengthening wei, dispelling wind, warming cold fluid, tonifying lung and spleen, tonifying vital energy, dispelling wind, releasing exterior with pungent-warm, dredging channels and stopping rhinorrhea and is therefore capable of treating allergic rhinitis.

The inventiondiscloses a traditional Chinese medicine for treating nasal rhinitis and allergic rhinitis. The formula of the traditional Chinese medicine comprises the following components in parts by weight: 5 to 8 parts of radix sophoraeflavescentis, 2 to 5 parts of floslonicerae, 2 to 5 parts of radix scutellariae, 3 to 5 parts of radix angelicae, 2 to 5 parts of coptischinensis, 3 to 8 parts of flosmagnoliae, 5 to 8 parts of fructus xanthii, 2 to 3 parts of mentha camphor, 5 to 8 parts of herba centipedae, 1 to 3 parts of boviscalculus artifactus, 3 to 5 parts of sweet wormwood herb, and 3 to 5 parts of herba schizonepetae. The traditional Chinese medicine takes pure naturaltraditional Chinese medicines as the raw materials, gel prepared through the traditional Chinese medicine has the effects of realizingaroma resuscitation, relieving the swelling, dispersing accumulation of pathogen, promoting blood circulation to dispel blood stasis, removing the necrotic tissue, realizingantibiosis, relieving inflammation, inflammation and dispersing dampness, realizingantianaphylaxis and repairingnasal mucosa, and is convenient to use;the drug efficacy can rapidly reach focuses, the absorptivity of the gel is more than 5 times that of traditional gel, and the gel does not have toxic or side effects.

A traditional Chinese medicine for remedying the allergic chronic rhinitis belongs to the traditional Chinese medicine for remedying the rhinitis. The traditional Chinese medicine consists of 30g of Szechwan lovage rhizomes, 30g of small centipede herb, 6g of Manchurian wild ginger, 6g of biond magnolia flower and 3g of natural indigo. The dosage materials in the prescription are all made from natural traditional Chinese herbal medicines by a traditional processing method. The materials can be easily gotten; the prescription and the preparation method are simple; the expense for preparing the medicine is low. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the disease of the allergic chronic rhinitis is low, which solves the treatment problem, which is caused by low family income, poor living and lack of local medical treatment condition. No adverse reaction occurs during the treatment process that the patient takes the prescription.

The invention belongs to the field of gel preparation and particularly relates to compound nasal gel for treating allergic rhinitis and a preparing method thereof. The compound nasal gel is prepared from baicalin, carbomer, ephedrine hydroehloride, borax, glycerin, ethylparaben, menthol, ethanol and distilled water. The nasal gel spray has the advantages of accurate therapeutic effect, stable properties and small adverse reaction is prepared through the selection of the baicalin which has remarkable antimicrobial, anti-inflammatory and anti-allergic effects, the cold-irritating menthol and a low dosage of ephedrine hydroehloride and the use of the high-molecular carbomer as a carrier. The compound nasal gel is used for treating allergic rhinitis.

A pharmaceutical or veterinary composition, comprises a first active agent selected from a dehydroepiandrosterone and / or dehydroepiandrosterone-sulfate, or a salt thereof, and a second active agent comprising a glucocorticosteroid for the treatment of asthma, chronic obstructive pulmonary disease, allergic rhinitis, or any other respiratory disease. The composition is provided in various formulations and in the form of a kit. The products of this patent are applied to the prophylaxis and treatment of asthma, chronic obstructive pulmonary disease, or any other respiratory disease.

The invention discloses a medicament for treating allergic rhinitis and acute rhinitis and relates to a traditional Chinese medicinal preparation. The formula of the medicament comprises the following components: 15 to 25g of ginseng, 12 to 18g of large head atractylodes rhizome, 12 to 18g of indian buead, 4 to 6g of liquorice, 50 to 70g of astragalus, 10 to 15g of divaricate saposhnikovia root, 10 to 15g of biond Magnolia flower, 13 to 17g of siberian cocklour fruit, 10 to 14g of Chinese magnoliavine fruit, 6 to 10g of acorus root, 12 to 18g of lightyellow sophora root, 10 to 20g of dark plum fruit, 10 to 20g of largetrifoliolious bugbane rhizome, 8 to 12g of cicada slough and 5 to 7g of belvedere fruit. The traditional Chinese medicines in the formula are decocted in water, condensed and then prepared into particles. The medicament has the outstanding characteristic of good treatment effect, wherein the total efficiency can be up to 96 percent. The medicament is convenient to use and is orally taken after being dissolved in boiled water, is safe, is normally taken and has no toxic and side effects.

The invention relates to a configuration method of water solubility gel or paste containing montmorillonite, a purpose in preventing and treating allergic rhinitis (including perennial rhinitis and seasonal rhinitis) through local nasal cavity outer side (nose wing and nose bridge) administration and a purpose in treating skin allergy through the local administration of allergic skin infected part.

The invention relates to a desloratadine oral dispersible film which comprises desloratadine, biologically-acceptable water-soluble polymers, plasticizers, purified water and the like, can be dispersed or dissolved quickly in the oral cavity, and is used for treating allergic rhinitis, allergic rhinitis and asthma syndrome, allergic nasal conjunctivitis, allergic dermatitis, allergic asthma and the like. The desloratadine oral dispersible film is free of irritation, convenient to take and carry, fast in effect, good in taste and particularly suitable for being used by the olds and children.

The invention relates to a medicament for treating allergic rhinitis, mainly comprising the following Chinese herbal medicines as raw materials: magnolia flower, xanthium, radix sileris, angelica, honeysuckle, caulis akebiae, glabrous greenbrier rhizome, liquorice and the like. The medicament is prepared by decocting the raw materials repeatedly by soft fire, concentrating the decoction into thick paste, and then adding conventional adjuvants to prepare clinically acceptable tablets, capsules, pills, particles, powder, injection or ointment. The medicament provided by the invention has the efficacies of removing cold, promoting the dispersing function of the lung, promoting blood circulation, expelling wind and promoting the restoration of consciousness, and can be used for treating various types of allergic rhinitis.