90results about How to "Improve drug utilization" patented technology

The invention discloses a health-care eye patch composed of a back lining layer (1), heating bodies (2), a middle interlayer (3), a gel layer (4) and a lining membrane (5). The heating bodies (2) are located between the back lining layer (1) and the middle interlayer (3), the gel layer (4) is located between the middle interlayer (3) and the lining membrane (5) and attached and applied to the eyes, the heating bodies (2) continuously release heat to enable drugs or other active ingredients in the gel layer (4) to be released sufficiently and rapidly to act on the attached and applied portions, and significant effects on eliminating eye swellings, relieving eye fatigue, improving black eyes and crow's feet and the like are achieved. The health-care eye patch has the advantages of being high in drug utilization ratio, rapid in action, safe and comfortable to use and the like.

The invention relates to a herbal drug for hemorrhoids with natural plants, in particular to a drug with specific formulation, comprising a plurality of active pharmaceutical ingredients, certain amount of penetration enhancer and certain amount of pharmacyeutical adjuvant with the following weight proportion. The active pharmaceutical ingredient comprises one hundred shares of sophoricoside, eighty shares of panax notoginseng, one hundred and ten shares of lightyellow sophora root, one hundred shares of bletilla striata, one hundred shares of common cnidium fruit, one hundred shares of patrinia scabiosaefolia link, sixty-five shares of moxa leaf, eighty shares of pursslane, sixty-five shares of honeysuckle, sixty-five shares of parsnip, fifty shares of alumen, fifty shares of borax, five shares of borneol, and thirty shares of licorice. The penetration enhancer comprises a certain amount of laurocapram and a certain amount of propanediol with the weight proportion of eighty to fifteen - thirty; the adding amount of the penetration enhancer is point zero eight to point four percent of the weight of the active pharmaceutical ingredient. The drug has the advantage of being more effective than oral drugs and external lotion due to full play of effective ingredients by adding penetration enhancer in specific prescription and formulation.

A solid essential balm contains menthol, holly oil, eucalyptus oil, camphor, cloves oil, and solid oil. Its advantages are high utilization rate, durable effect and low volatility.

The invention discloses an auxiliary treatment device for child allergic asthma. The auxiliary treatment device mainly comprises a spraying device, a control device, an atomizing device, an air purification device, a ventilation pipe, a rotating shaft, a telescopic air pipe, a box body, a gas mixing tank, a fixed valve, an oxygen adding hole, an air funnel, a purification air pipe, an air pump, a gas collecting box, a clamping groove, a connecting top cover, a fan and an air quality sensor. The spraying device, the atomizing device and the air purifying device are controlled in an integrated mode and act together, spraying is uniform, countercurrent pollution cannot be caused, and cleaning and disinfecting are easy; the air purification device uses a four-layer multifunctional filter system composed of a pre-filtering net, an ionization filter screen, an activated carbon filter screen and an HEPA filter screen; the atomizing device is a gas compression type atomizer, the human body inhales oxygen comfortably, the oxygen can enter tracheae such as the bronchus and the lungs, the clinical effect is excellent, and the auxiliary treatment device is particularly suitable for treatment of respiratory diseases, convenient to use, accurate in curative effect, reasonable in design and capable of being widely applied clinically.

The invention discloses a method for preparing a location targeting polysaccharide gum carrier material. According to the method, water-based ferroferric oxide is coated with calcium pectinate, a drug carrier is made with a low-methoxyl pectin carrier as a framework material, the ferroferric oxide is modified by a hydrophile group, targeting is achieved through the magnetic ferroferric oxide, drugs are located in the diseased region by means of the external magnetic field and then released, and in this way, drug content in normal tissue is reduced, drug utilization rate is increased, and drug toxicity is reduced; by taking the low-methoxyl pectin carrier as the framework material, toxicity is avoided, safety is achieved, biocompatibility and biodegradability are high, the therapeutic index of drugs can be increased, drug toxicity can be reduced, and the side effects of drugs can be reduced.

The invention provides a wicker anti-cracking color-protecting drying method, and relates to the technical field of wicker plaiting article production. Before wicker is cut down, anti-cracking color-protecting liquid medicine is injected into the wicker from the rootstock of the wicker or the root of a branch; when the anti-cracking color-protecting liquid medicine is detected at the end of the branch, the wicker can be cut; leaves of the cut-down wicker are removed, and then the wicker is soaked into a solution for 2 h, wherein the solution is prepared on the basis that the ratio of glycerinum to water is 1:10; then, the wicker is taken out and dried, then soaked in molten paraffin wax and taken out, and the surface of the wicker is completely wrapped by paraffin wax; a fine sand and salt mixture is an embedding agent, slow heating is performed, and drying and softening are performed on the wicker. The living wicker processing technology is simple, and a traditional wicker postprocessing method is broken through; after living wicker anti-cracking color-protecting drying processing, the wicker can be directly used for plaiting wicker products, the original color of the wicker can be kept, the wicker is not likely to crack, and the medicine utilization rate is greatly improved compared with a traditional method.

The invention provides a reservoir type ropivacaine pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition comprises: ropivacaine, a pharmaceutical solvent, a medicinal phospholipid, medicinal oil, and pharmaco enhancers, a non-essential antioxidant and a non-essential acid-base regulator. The pharmaceutical composition has a controllable release behavior and a sustained release effect, can significantly reduce the peak serum concentration of the drug, maintain a stable plasma concentration in the body, prolong the effective treatment time, reduce the effective therapeutic dose, improve the utilization of the drug, and reduce the risk of neurotoxicity. The pharmaceutical composition has a long-lasting analgesic effect and can be used for pain treatment.

The invention provides a preparation method of drug balloons as well as the drug balloons prepared by the preparation method and application thereof. The preparation method is characterized by comprising the following steps: curing chitosan to surfaces of balloons to obtain balloons with surfaces modified by the chitosan; spraying a drug solution on the obtained balloons with the surfaces modified by the chitosan to obtain the balloons with surfaces provided with drug coatings; carrying out surface solvation treatment on the balloons and carrying out segmented folding and packing to obtain the drug balloons. According to the drug balloons prepared by the preparation method provided by the invention, the drug coatings can be uniformly and firmly combined on the surfaces of the balloons and not easily fall off; drugs are prevented from being washed off in an in-vivo conveying process; the loss of drugs is reduced and the utilization rate of the drugs is improved; the preparation method provided by the invention is accurate, stable and efficient, is suitable for industrial large-scale production and has a wide application prospect.

The invention relates to an electromagnetic-detection-based intelligent greenhouse pesticide spraying robot and method. The intelligent greenhouse pesticide spraying robot is composed of a central controller, an electromagnetic detection identification path module, a permanent magnet detection module, an image processing module, a pesticide spraying module, a pesticide dispensing module, a drug detection module, a wireless communication module, a human-computer interaction module, a self-state detection module, a driving module, an alarm module, a storage module block, and a power supply module. The central controller is connected with the electromagnetic detection identification path module, the permanent magnet detection module, the image processing module, the pesticide spraying module, the pesticide dispensing module, the drug detection module, the wireless communication module, the human-computer interaction module, the self-state detection module, the driving module, the alarm module, the storage module block, and the power supply module. According to the invention, the whole pesticide spraying process of fruit and vegetable plants in a greenhouse can be completed intelligently; the pesticide wasting and residue can be reduced; the work efficiency and pesticide utilization rate can be improved; and thus people can be protected from being injured by the pesticide.

The invention discloses a high-molecular anti-tumor medicine for bonding a vascular disrupting agent and an immunomodulatory agent and a preparation method thereof. According to the high-molecular anti-tumor medicine, a polyethylene glycol block and a polylactide block serve as main chains, and the vascular disrupting agent and immunomodulatory agent pharmaceutical molecules are grafted and bondedat the same time on the main chins through chemical reactions such as a sulfydryl-alkene light click reaction, an esterification reaction and a nitrine-alkyne cyclic addition reaction. Due to the synergistic effect of the tumor vascular occlusion therapy and the immune therapy, the high-molecular anti-tumor medicine improves the anti-cancer activity under the condition that the dosage of the medicine is reduced, and the defects that a traditional chemotherapeutic has difficulty in infiltrating in tumor cells and has drug resistance are avoided; meanwhile, the immune therapy is used for activating the immune system of a patient to kill the tumor cells for a long time, and clinical tumor metastasis and relapse are effectively prevented. In addition, a synthetic method of the anti-tumor polymer bonding medicine has the advantages of being simple, effective, mild in reaction condition and the like.

The invention belongs to the technical field of detection and treatment of ophthalmic diseases and particularly discloses an intraocular-pressure continuous glaucoma detection and drug delivery systemwhich comprises a corneal contact lens. An intraocular-pressure detection circuit and a drug delivery circuit are integrated in the corneal contact lens, the intraocular-pressure detection circuit isused for detecting intraocular-pressure information and transmitting the intraocular-pressure information to a single chip microcomputer outside the corneal contact lens in a wireless manner, and thesingle chip microcomputer judges the intraocular pressure according to the received information. When the intraocular pressure is beyond a normal range, the single chip microcomputer wirelessly supplies power to the drug delivery circuit, and a drug is delivered after rectification by the drug delivery circuit. The detection system can continuously detect the fluctuation of the intraocular pressure and the abnormal increase of the intraocular pressure for a long time, can timely adopt an iontophoresis mode to carry out controllable drug delivery when the intraocular pressure exceeds the normal range, and ensures the real-time detection of the intraocular pressure and timely, efficient and controllable drug treatment. In addition, the system has the advantages of portability, small irritation to eyes, no limitation by places and time for diagnosis and treatment of glaucoma, high drug utilization rate and the like.

A Chinese medicine in the form of ointment for treating hypersteogeny, bone fracture, arthrodynia, arthritis, etc is prepared from multiple Chinese-medicinal materials including Sichuan aconite root, hot pepper, myrrh, safflower, etc. Its preparing process is also disclosed.

The invention provides a method for treatment of oily sludge. The method includes the steps of primary conditioning and tempering treatment, namely adding sludge, water, a demulsifier and a flocculantin a certain proportion, and diluting the sludge to the flow state from a viscous state via full mixing with mechanical stirring; ultrasonic treatment, namely heating a sludge and water mixture subjected to primary conditioning and tempering into 45-55DEG C for ultrasonic treatment; secondary conditioning and tempering treatment, namely adding an alkaline dispersing agent and a dehydrating agentto carry out secondary conditioning and tempering treatment on depth-level oil which is not completed separated in the previous treatment for further oil-solid separation; centrifugal separation; drying and oil-water layer separation.

The invention discloses an iontophoresis microneedle patch which comprises a microneedle array, an elastomer located on the lower surface of a microneedle array substrate, non-elastic drug-loaded hydrogel, a flexible circuit board and an anti-seepage adhesive ring. The flexible circuit board comprises a drug delivery electrode and a loop electrode, and the drug delivery electrode and the loop electrode are respectively and correspondingly connected with an external iontophoresis instrument. According to the microneedle patch disclosed by the invention, three transdermal drug delivery modes ofdrug-loaded hydrogel, the microneedle and iontophoresis are integrated into one patch through an ingenious structure, so that the transdermal drug delivery effect can be improved more efficiently. Theinvention further provides a preparation method of the iontophoresis microneedle patch.

The invention relates to a deep dehydration pretreatment process for landfill sludge. The deep dehydration pretreatment process comprises the following steps of (1) performing viscosity measurement onexcess sludge of a sewage treatment plant to obtain a sludge viscosity standard range; (2) diluting to-be-treated landfill sludge based on the sludge viscosity standard range obtained in step (1), then measuring the viscosity of the to-be-treated landfill sludge so that the viscosity of the diluted landfill sludge is within the sludge viscosity standard range and is smaller than a maximum value of the sludge viscosity standard range; and (3) adding a chemical conditioning agent to the diluted landfill sludge, conditioning and then dehydrating the diluted landfill sludge to obtain the deep dehydration pretreatment sludge having a water content of less than 60%, and recycling the sludge dehydration liquid for diluting the landfill sludge. Compared with the prior art, the deep dehydration pretreatment process for the landfill sludge effectively reduces the generation of the dehydration liquid and maximizes the effect of the medicament by using the sludge viscosity as a reference for thelandfill sludge dilution degree, and fills in the gap of the technical field of pretreatment before conditioning of the landfill sludge.

The invention discloses an elastic polyurethane antibacterial material and a preparation method thereof. The preparation method comprises the steps: subjecting tartaric acid and polyhydric alcohols toa catalytic reaction to obtain modified polyhydric alcohols, then adding an antibacterial agent and an emulsifier into the modified polyhydric alcohols, feeding nitrogen for cooling after a period ofhigh-temperature reaction, adding polyisocyanate and a chain extender into the reactants, and terminating with gastrodin to obtain the elastic polyurethane antibacterial material. The antibacterial material disclosed by the invention can generate ROS stimulation response in the presence of bacteria, so that the medicine utilization rate is effectively improved. The tartaric acid provided by the invention has a large number of active functional groups, a cross-linked network structure can be formed, the cross-linking density of the network structure can be changed by adjusting the proportion of synthetic raw materials, and the drug release rate during response of the antibacterial material is regulated and controlled. The added gastrodin can improve the mechanical property and the deformation resistance of the polyurethane antibacterial material, so that the polyurethane antibacterial material still has good physical and mechanical properties after chemical bonds are broken in the ROSresponse drug release process.

The invention provides an air-ground cooperative pesticide application method and system. The method comprises the steps that: target information of a to-be-operated orchard is obtained, wherein the target information includes geographic feature information and fruit tree feature information; according to the target information, a collaborative operation path of a plant protection unmanned aerial vehicle and a ground pesticide application unmanned vehicle is determined; and the plant protection unmanned aerial vehicle and the ground pesticide application unmanned vehicle are controlled to operate according to the collaborative operation path. According to the air-ground cooperative pesticide application method and system of the invention, the collaborative operation path is planned according to the feature information of orchards and fruit trees; on this basis, the plant protection unmanned aerial vehicle and the ground pesticide application unmanned vehicle are controlled to operate according to the planned collaborative operation path; the ground pesticide application unmanned vehicle is utilized to perform supplementary operation on an operation blind area of the plant protection unmanned aerial vehicle in an air-ground collaborative pesticide spraying mode, and therefore, pesticide liquid can fully cover the fruit trees, the pesticide utilization rate is improved to the maximum extent, negative effects caused by unreasonable pesticide spraying are reduced, environmental pollution is reduced, the pesticide spraying control mode and effect are optimized, fruit tree diseases and insect pests are effectively prevented and treated, and stable yield and yield increase of fruits can be effectively guaranteed.

The invention provides an anti-cracking and color-protecting drying method for a rattan, and relates to the technical field of production of rattan-woven products. Anti-cracking and color-protecting chemical liquid is injected into the rhizome of the rattan or the root of the twig before the rattan is cut down. When it is detected that the anti-cracking and color-protecting chemical liquid exists at the tail end of the twig, the rattan is cut down. The cut rattan is soaked in a solution prepared from glycerinum and water according to the proportion of 1:10 for two hours after the leaves of the rattan are removed. Then the rattan is taken out, dried, soaked in molten paraffin again and taken out so that the surface of the rattan can be completely wrapped by the paraffin. Fine sand is used as an embedding medium, the rattan is heated slowly, dried and softened. The processing technology for the living rattan is simple and breaks through a traditional rattan post-processing method. After the living rattan is subjected to anti-cracking and color-protecting drying treatment, the rattan can be directly used for weaving rattan-woven products, the original color of the rattan is kept, the rattan is not prone to cracking, and the chemical utilization rate is greatly improved compared with the traditional method.