Clinical nutritional composition for promoting ulcerative colitis mucosa repair and preparation method of clinical nutritional composition

Abstract

The invention discloses a clinical nutritional composition for promoting ulcerative colitis mucosa repair and a preparation method of the clinical nutritional composition. The clinical nutritional composition is prepared from the following components in parts by mass: protein, carbohydrate, fat, apigenin, butyric acid compounds, walnut oligopeptide, calcium, iron, zinc, potassium, magnesium, phosphorus, selenium, copper, chromium, molybdenum, iodine, vitamin D, vitamin C, vitamin A, vitamin B1, vitamin B2, vitamin B3, vitamin B6, folic acid, vitamin B12, vitamin E, vitamin K, biotin and pantothenic acid. The composition aims at the characteristics of two diseases of intestinal mucosa injury and colon motility abnormality of UC patients, can quickly supply energy, inhibit inflammation and recover colon motility, further accelerates repair of colon mucosa, improves the nutrient absorption rate and drug utilization rate, and achieves the goals of inducing and maintaining clinical relief and mucosa healing, preventing and treating complications and improving the activity period UC treatment of the life quality of the patients.

Description

technical field [0001] The invention belongs to the technical field of food for special medical treatment, and in particular relates to a clinical nutritional composition for promoting mucosal repair of ulcerative colitis and a preparation method thereof. Background technique [0002] Ulcerative colitis (UC) is a chronic nonspecific inflammatory disease of the colon and rectum with multiple etiologies, which belongs to inflammatory bowel disease (IBD). With the rapid development of my country's social economy, people's eating habits, rhythm of life and environment have changed significantly, making the incidence of UC on the rise. [0003] UC patients, especially those with severe disease or persistent disease, generally have malnutrition, such as emaciation, anemia, hypoproteinemia, etc., and their drug treatment also has the characteristics of large dosage, many combinations, and high dependence. This is mainly due to the following two clinical problems in UC patients: ...

AI Technical Summary

Problems solved by technology

Although decomposing dietary fiber can supply colonic energy and regulate intestinal flora, the colonic mucosa of patients with moderate to severe UC during the acute attack stage is severely damaged, and intestinal stenosis and intestinal obstruction are prone to occur. Guidelines require a slag-free diet, and the disordered Intestinal flora cannot meet the conditions for decomposing dietary fiber, which unreasonably increases the intestinal burden

At the same time, no enteral nutrition preparation has paid attention to the important issue of abnormal colonic motility in UC patients. Frequent diarrhea not only affects the retention and absorption of drugs and weakens the therapeutic effect, but also affects the effective absorption of nutrients in the damaged colon. One of the key points where UC patients fail to take advantage of disease remission

[0010] UC patients have a low level of knowledge about disease-related diet, but they have a positive attitude towards diet, are willing to accept dietary behavior correction, and have high compliance. At the same time, the current enteral nutrition preparations on the market are difficult to adapt to the treatment of UC. Diet guidance for ulcerative colitis More generally, therefore, it is necessary to provide a new clinical nutritional composition to promote ulcerative colitis mucosal repair to cooperate with drug treatment, correct malnutrition as soon as possible, relieve clinical symptoms, shorten the onset period and other problems

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