The application relates to the technical field of
drug carrier materials, in particular to a
starch-based
capsule and a preparation method thereof, which comprises the following steps: S1, after
dialdehyde starch is gelatinized, the
dialdehyde starch is mixed with a
tannic acid solution, an
iron chloride solution is added, uniform mixing and defoaming are carried out, and a film-forming solution is obtained; S2, a mold is immersed in the film-forming solution, preliminary
drying is carried out under a set temperature and
humidity condition after pulling up, and a gel film layer is formed; S3, the gel film layer after preliminary
drying is demolded,
humidity balance and
drying are sequentially carried out, and the
starch-based
capsule is obtained. By adding
tannic acid and a suitable amount of
iron chloride, an effective crosslinking
network structure is formed among
starch molecules, the
mechanical strength of the
capsule shell is enhanced, and the hygroscopicity is reduced.