Probiotic composition capable of preventing and relieving Alzheimer's disease, and application of probiotic composition

Abstract

The invention belongs to the technical field of biological active bacterial preparations, particularly relates to a probiotic composition capable of obviously preventing and relieving the Alzheimer'sdisease, and further discloses a preparation prepared from the probiotic composition for preventing and relieving the Alzheimer's disease. The probiotic composition capable of obviously preventing andrelieving the Alzheimer's disease comprises lactobacillus plantarum Lp3a, bifidobacterium lactis Bla019, bifidobacterium longum BL5b, lactobacillus buchneri Lbu3, propionibacterium freudenreichii PrF01, propionibacterium shermanii, pediococcus acidilactici, clostridium butyricum and lactobacillus fermenti. The probiotic composition not only can obviously regulate and maintain intestinal microecology and control an in vivo toxin level but also can generate a certain quantity of short chain fatty acid, including acetic acid, propionic acid, butyric acid, lactic acid and the like to further relieve the related symptoms of the Alzheimer's disease. The probiotic composition has the efficacy of alleviating and relieving the symptoms of the Alzheimer's disease, also has the efficacy of soothingthe nerves and calming down, and also has a certain function for the depression, the anxiety disorder and the insomnia.

Description

technical field [0001] The invention belongs to the technical field of biological bacterial agents, specifically relates to a probiotic composition capable of significantly preventing and improving senile dementia, and further discloses a preparation for preventing and improving senile dementia prepared from the probiotic composition. Background technique [0002] With the continuous development of human living standards and medical standards, population aging has become an international hot issue. In fact, the problem of population aging on a global scale is more serious than previously expected. According to the provisions of the Chinese Medical Association Geriatrics Branch, the elderly are counted as 60 years old and above in my country. The total number of elderly people in China has reached 130 million, accounting for about 10% of the total population, and it is expected that by 2030, this proportion will increase. to 25%. Along with the increasingly serious problem of...

AI Technical Summary

Problems solved by technology

On the one hand, diseases of the nervous system may cause intestinal flora disturbances. For example, the latest scientific research data show that the contents of Firmicutes and Bifidobacterium in the intestinal tract of AD patients are significantly reduced, while the content of Bacteroidetes On the other hand, an imbalanced intestinal bacterial flora can further cause physiological lesions in the nervous system, such as the metabolites of many bad bacteria (lipopolysaccharides, LPS) entering the circulatory system may damage the blood brain The integrity of the barrier (BBB), and further cause the infiltration of inflammatory cells in the central nervous system, thereby damaging the central nervous system

In addition, a large number of recent studies have also found that the imbalance of intestinal flora homeostasis may be closely related to abnormal blood lipid metabolism in the whole body

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