Probiotic composition capable of preventing and relieving Alzheimer's disease, and application of probiotic composition

A technology for Alzheimer's disease and probiotics, applied in applications, drug combinations, bacteria used in food preparation, etc., can solve problems such as intestinal flora disturbance, physiological lesions of the nervous system, and infiltration of inflammatory cells in the central nervous system.

Pending Publication Date: 2020-05-29
江苏佰澳达生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

On the one hand, diseases of the nervous system may cause intestinal flora disturbances. For example, the latest scientific research data show that the contents of Firmicutes and Bifidobacterium in the intestinal tract of AD patients are significantly reduced, while the content of Bacteroidetes On the other hand, an imbalanced intestinal bacterial flora can further cause physiological lesions in the nervous system, such as the metabolites of many b

Method used

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  • Probiotic composition capable of preventing and relieving Alzheimer's disease, and application of probiotic composition
  • Probiotic composition capable of preventing and relieving Alzheimer's disease, and application of probiotic composition
  • Probiotic composition capable of preventing and relieving Alzheimer's disease, and application of probiotic composition

Examples

Experimental program
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Effect test

Embodiment 1

[0039] The probiotic composition described in this example includes the following components in parts by weight: 1 g of Lactobacillus plantarum, 50 g of Bifidobacterium lactis, and 1 g of Bifidobacterium longum.

Embodiment 2

[0041] The probiotic composition described in this example includes the following components in parts by weight: 50 g of Lactobacillus plantarum, 1 g of Bifidobacterium lactis, and 50 g of Bifidobacterium longum.

Embodiment 3

[0043] The probiotic composition described in this example includes the following components in parts by weight: 25g of Lactobacillus plantarum, 25g of Bifidobacterium lactis, and 25g of Bifidobacterium longum.

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Abstract

The invention belongs to the technical field of biological active bacterial preparations, particularly relates to a probiotic composition capable of obviously preventing and relieving the Alzheimer'sdisease, and further discloses a preparation prepared from the probiotic composition for preventing and relieving the Alzheimer's disease. The probiotic composition capable of obviously preventing andrelieving the Alzheimer's disease comprises lactobacillus plantarum Lp3a, bifidobacterium lactis Bla019, bifidobacterium longum BL5b, lactobacillus buchneri Lbu3, propionibacterium freudenreichii PrF01, propionibacterium shermanii, pediococcus acidilactici, clostridium butyricum and lactobacillus fermenti. The probiotic composition not only can obviously regulate and maintain intestinal microecology and control an in vivo toxin level but also can generate a certain quantity of short chain fatty acid, including acetic acid, propionic acid, butyric acid, lactic acid and the like to further relieve the related symptoms of the Alzheimer's disease. The probiotic composition has the efficacy of alleviating and relieving the symptoms of the Alzheimer's disease, also has the efficacy of soothingthe nerves and calming down, and also has a certain function for the depression, the anxiety disorder and the insomnia.

Description

technical field [0001] The invention belongs to the technical field of biological bacterial agents, specifically relates to a probiotic composition capable of significantly preventing and improving senile dementia, and further discloses a preparation for preventing and improving senile dementia prepared from the probiotic composition. Background technique [0002] With the continuous development of human living standards and medical standards, population aging has become an international hot issue. In fact, the problem of population aging on a global scale is more serious than previously expected. According to the provisions of the Chinese Medical Association Geriatrics Branch, the elderly are counted as 60 years old and above in my country. The total number of elderly people in China has reached 130 million, accounting for about 10% of the total population, and it is expected that by 2030, this proportion will increase. to 25%. Along with the increasingly serious problem of...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K35/745A61K35/744A61K35/74A61P25/28A23L33/135
CPCA61K35/747A61K35/745A61K35/744A61K35/74A61P25/28A23L33/135A23V2002/00A23V2400/533A23V2400/169A61K2300/00A23V2200/322
Inventor 马凯王辉王广贤王润鑫张常亮
Owner 江苏佰澳达生物科技有限公司
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