Anti-allergy soothing composition and preparation method and cosmetic thereof

Abstract

The invention discloses an anti-allergy soothing composition as well as a preparation method and cosmetics thereof. The anti-allergy soothing composition comprises the following components in percentage by mass: 2%-8% of a cactus extract, 1%-5% of a radix scutellariae root extract, 0.5%-3% of a Chinese herbaceous peony root extract, 2%-5% of a radix ophiopogonis root extract, 2%-5% of an oat bran extract, 40%-50% of butanediol and the balance of water. The composition has good anti-allergy and soothing effects, when the composition is applied to skin care products and cosmetics, the cosmetics can have the good anti-allergy and soothing effects, and the skin care products and the cosmetics can have good universality. Meanwhile, the preparation method of the anti-allergy soothing composition is simple and easy to implement and easy to popularize and use.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to an anti-allergic soothing composition, a preparation method thereof, and cosmetics. Background Art

[0002] With environmental changes, increasing life pressure and the increasing use of cosmetics, skin sensitivity problems are becoming more and more common. Sensitive skin is prone to discomfort symptoms such as redness, swelling, itching, stinging, dryness and desquamation, which not only affects the health and beauty of the skin, but also reduces people's quality of life. Therefore, the development of cosmetics with good anti-allergic and soothing effects has an important market demand. Summary of the invention

[0003] Based on the above problems, the present invention provides an anti-allergic soothing composition and a preparation method thereof and cosmetics. The composition has good anti-allergic soothing effects, and when applied to skin care products and cosmetics, the skin care products and cosmetics can have good anti-allergic soothing effects, and can also have good universality.

[0004] To achieve the above object, the present invention adopts the following technical solutions:

[0005] An anti-allergic soothing composition comprises the following components in percentage by mass: 2% to 8% of cactus extract, 1% to 5% of scutellaria root extract, 0.5% to 3% of peony root extract, 2% to 5% of ophiopogon root extract, 2% to 5% of oat bran extract, 40% to 50% of butylene glycol and the balance of water.

[0006] In some of the embodiments, the anti-allergic soothing composition includes the following components in percentage by mass: 4% to 6% cactus extract, 2% to 4% scutellaria root extract, 1% to 2.5% peony root extract, 2.5% to 4% ophiopogon root extract, 3% to 4% oat bran extract, 43% to 48% butylene glycol and the remainder water.

[0007] A method for preparing the anti-allergic soothing composition comprises the following steps:

[0008] Obtain the cactus extract, the Scutellaria baicalensis root extract, the Paeonia lactiflora root extract, the Ophiopogon japonicus root extract, the oat bran extract, the butylene glycol and the water according to their respective mass percentages;

[0009] Mixing the butanediol and the water to obtain a mixed solution;

[0010] The cactus extract, the Scutellaria baicalensis root extract, the Paeonia lactiflora root extract, the Ophiopogon japonicus root extract and the oat bran extract are sequentially added to the mixed solution, and each time an extract is added, it is stirred evenly at a temperature of 40° C. to 50° C.

[0011] In some embodiments, the preparation of the cactus extract comprises the following steps:

[0012] Cut the cactus into cactus slices with a thickness of 0.5 cm to 3 cm;

[0013] Mixing the cactus flakes with water to obtain a first mixture, wherein the mass ratio of the cactus flakes to water is 1:(5-10);

[0014] The first mixture is heated under reflux for 1 h to 5 h, and then filtered to obtain a first filtrate;

[0015] The water in the first filtrate is removed to obtain the cactus extract.

[0016] In some embodiments, the preparation of the scutellaria root extract comprises the following steps: mixing scutellaria root powder with water to obtain a second mixture, wherein the mass ratio of the scutellaria root powder to water is 1:(8-12);

[0017] The second mixture is heated under reflux for 1 h to 5 h, and then filtered to obtain a second filtrate;

[0018] The pH value of the second filtrate is adjusted to 1-5, solid matter is precipitated, and then filtered to obtain a first precipitate;

[0019] The first precipitate is recrystallized to obtain the Scutellaria baicalensis root extract in a solid phase.

[0020] In some embodiments, the preparation of the peony root extract comprises the following steps:

[0021] Mixing peony root powder with water to obtain a third mixture, wherein the mass ratio of the peony root powder to water is 1:(6-10);

[0022] The third mixture is heated under reflux for 1 h to 3 h, and then filtered to obtain a third filtrate;

[0023] The water in the third filtrate is removed to obtain the peony root extract.

[0024] In some embodiments, the preparation of the Ophiopogon japonicus root extract comprises the following steps:

[0025] Mixing the root of Ophiopogon japonicus with water to obtain a fourth mixture, wherein the mass ratio of the root of Ophiopogon japonicus to water is 1:(8-12);

[0026] The fourth mixture is extracted at 80° C. to 90° C. for 1.5 h to 3 h, and then filtered to obtain a fourth filtrate;

[0027] The water in the fourth filtrate is removed to obtain the Ophiopogon japonicus root extract.

[0028] In some embodiments, the preparation of the oat bran extract comprises the following steps:

[0029] Mixing oat bran powder with sodium hydroxide solution to obtain a fifth mixture, wherein the mass ratio of the oat bran powder to the sodium hydroxide solution is 1:(10-15), and the mass concentration of sodium hydroxide in the sodium hydroxide solution is 0.5%-1%;

[0030] The fourth mixture is extracted at 40° C. to 50° C. for 1 h to 2 h, and then filtered to obtain a fifth filtrate;

[0031] The pH value of the fifth filtrate is adjusted to 6-7, solid matter is precipitated, and then filtered to obtain a second precipitate;

[0032] The second precipitate is recrystallized to obtain the oat bran extract in a solid phase.

[0033] A cosmetic comprising the anti-allergic soothing composition.

[0034] In some embodiments, the anti-allergic soothing composition accounts for 0.5% to 10% by mass of the cosmetic.

[0035] Beneficial Effects

[0036] The composition of the present invention has a good anti-allergic and soothing effect. When applied to cosmetics, the cosmetics can have a good anti-allergic and soothing effect, and the cosmetics can have good universality. The cactus extract is rich in a variety of bioactive ingredients, such as polysaccharides, flavonoid compounds, etc., and has anti-oxidation, anti-inflammatory, moisturizing and other effects, can effectively relieve skin inflammatory reactions, and enhance the resistance of the skin. The Scutellaria root extract contains active substances such as baicalin, has significant antibacterial and anti-inflammatory effects, and can reduce the redness and pain caused by inflammation of the skin. The peony root extract has ingredients such as paeoniflorin, can relieve the tension of the skin, and promote the repair and regeneration of skin cells. The ophiopogon root extract is rich in ophiopogon polysaccharides, etc., has good moisturizing and antioxidant properties, and helps to maintain the moisture balance and healthy state of the skin. The oat bran extract is rich in β-glucan, etc., can form a protective film on the skin surface, enhance the barrier function of the skin, and reduce the damage to the skin by external stimuli. By rationally combining these natural plant extracts, an efficient, safe and universal anti-allergic and soothing composition can be obtained. Applying the composition to cosmetics can provide effective care solutions for people with sensitive skin. DETAILED DESCRIPTION

[0037] An embodiment of the present invention provides an anti-allergic soothing composition, comprising the following components in mass percentage: 2% to 8% of cactus extract, 1% to 5% of scutellaria root extract, 0.5% to 3% of peony root extract, 2% to 5% of ophiopogon root extract, 2% to 5% of oat bran extract, 40% to 50% of butylene glycol, and the remainder of water. The composition has good anti-allergic soothing effects. When applied to skin care products and cosmetics, the skin care products and cosmetics can have good anti-allergic soothing effects, and can make the skin care products and cosmetics have good universality. Cactus extract is rich in a variety of bioactive ingredients, such as polysaccharides, flavonoids, etc., and has antioxidant, anti-inflammatory, moisturizing and other effects, which can effectively relieve skin inflammatory reactions and enhance skin resistance. Scutellaria root extract contains active substances such as baicalin, has significant antibacterial and anti-inflammatory effects, and can reduce the redness and pain caused by inflammation of the skin. Peony root extract has ingredients such as paeoniflorin, which can relieve skin tension and promote the repair and regeneration of skin cells. Ophiopogon root extract is rich in Ophiopogon japonicus polysaccharides, etc., and has good moisturizing and antioxidant properties, which helps maintain the moisture balance and health of the skin. Oat bran extract is rich in β-glucan, etc., which can form a protective film on the skin surface, enhance the skin's barrier function, and reduce the damage to the skin caused by external stimuli. By rationally combining these natural plant extracts, an efficient, safe and universal anti-allergic soothing composition can be obtained. The composition can be applied to cosmetics to provide effective care solutions for people with sensitive skin.

[0038] Optionally, in the anti-allergic soothing composition, the mass percentage of the cactus extract may be 2%, 3%, 4%, 5%, 6%, 7%, 8%, etc. The mass percentage of the cactus extract may also be other values ​​within the range of 2% to 8%.

[0039] Optionally, in the anti-allergic soothing composition, the mass percentage of the Scutellaria baicalensis root extract may be 1%, 2%, 3%, 4%, 5%, etc. The mass percentage of the Scutellaria baicalensis root extract may also be other values ​​within the range of 1% to 5%.

[0040] Optionally, in the anti-allergic soothing composition, the mass percentage of the peony root extract can be 0.5%, 0.8%, 1%, 1.2%, 1.5%, 1.8%, 2%, 2.2%, 2.5%, 2.8%, 3%, etc. The mass percentage of the peony root extract can also be other values ​​within the range of 0.5% to 3%.

[0041] Optionally, in the anti-allergic soothing composition, the mass percentage of the Ophiopogon japonicus root extract can be 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc. The mass percentage of the Ophiopogon japonicus root extract can also be other values ​​within the range of 2% to 5%.

[0042] Optionally, in the anti-allergic soothing composition, the mass percentage of the oat bran extract may be 2%, 2.5%, 3%, 3.5%, 4%, 4.5%, 5%, etc. The mass percentage of the oat bran extract may also be other values ​​within the range of 2% to 5%.

[0043] Optionally, in the anti-allergic soothing composition, the mass percentage of butylene glycol can be 40%, 41%, 42%, 43%, 44%, 45%, 46%, 47%, 48%, 49%, 50%, etc. The mass percentage of butylene glycol can also be other values ​​within the range of 40% to 50%.

[0044] It is understandable that in the anti-allergic soothing composition, water is the balance. In the anti-allergic soothing composition, the sum of the mass percentages of cactus extract, scutellaria root extract, peony root extract, ophiopogon root extract, oat bran extract, butylene glycol and water is 100%.

[0045] In some embodiments, the anti-allergic soothing composition includes the following components in mass percentage: 4% to 6% of cactus extract, 2% to 4% of scutellaria root extract, 1% to 2.5% of peony root extract, 2.5% to 4% of ophiopogon root extract, 3% to 4% of oat bran extract, 43% to 48% of butylene glycol, and the balance of water. Further, the composition includes the following components in mass percentage: 5% of cactus extract, 3% of scutellaria root extract, 2% of peony root extract, 3.5% of ophiopogon root extract, 3.5% of oat bran extract, 45% of butylene glycol, and the balance of water.

[0046] It is understandable that each extract in the anti-allergic soothing composition of the present invention can be tested using the high performance liquid chromatography method of the 2020 edition of the "Chinese Pharmacopoeia".

[0047] Another embodiment of the present invention provides a method for preparing an anti-allergic soothing composition, comprising the following steps: obtaining cactus extract, scutellaria root extract, peony root extract, ophiopogon root extract, oat bran extract, butylene glycol and water according to their respective mass percentages. Butylene glycol and water are mixed to obtain a mixed solution. Cactus extract, scutellaria root extract, peony root extract, ophiopogon root extract and oat bran extract are added to the mixed solution in sequence, and each time an extract is added, it is stirred evenly at a temperature of 40°C to 50°C. In the preparation method, the preparation of the composition can be completed by a simple process, so that the components in the composition cooperate with each other to efficiently exert the anti-allergic soothing effect. The preparation method of the anti-allergic soothing composition is simple and easy to implement, and easy to promote and use.

[0048] Optionally, the stirring temperature after each addition of an extract can be 40°C, 41°C, 42°C, 43°C, 44°C, 45°C, 46°C, 47°C, 48°C, 49°C, 50°C, etc. Optionally, the stirring temperature can also be other values ​​within the range of 40°C to 50°C.

[0049] In some embodiments, the stirring time after each addition of an extract is 5 min to 20 min. For example, the stirring time can be 5 min, 8 min, 10 min, 12 min, 15 min, 18 min, 20 min, etc. Optionally, the stirring time can also be other values ​​within the range of 5 min to 20 min.

[0050] In some embodiments, the preparation of the cactus extract comprises the following steps: cutting the cactus into cactus slices with a thickness of 0.5 cm to 3 cm. Mixing the cactus slices with water to obtain a first mixture, wherein the mass ratio of the cactus slices to the water is 1:(5-10). The first mixture is heated to reflux for 1 h to 5 h, and then filtered to obtain a first filtrate. Water in the first filtrate is removed to obtain the cactus extract.

[0051] In the preparation process of cactus extract, the thickness of cactus slices can be 0.5 cm, 1 cm, 1.5 cm, 2 cm, 2.5 cm, 3 cm, etc. The mass ratio of cactus slices to water is 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, etc. The temperature of heating the first mixture to reflux is 90°C to 110°C, for example, the temperature of heating the first mixture to reflux is 90°C, 92°C, 95°C, 98°C, 100°C, 102°C, 105°C, 108°C, 110°C, etc. The time of heating the first mixture to reflux can be 1h, 2h, 3h, 4h, 5h, etc. The water in the first filtrate can be removed by vacuum filtration, spray drying, etc.

[0052] In some embodiments, the preparation of the Scutellaria baicalensis root extract comprises the following steps: mixing Scutellaria baicalensis root powder with water to obtain a second mixture, wherein the mass ratio of Scutellaria baicalensis root powder to water is 1:(8-12). The second mixture is heated to reflux for 1h-5h, and then filtered to obtain a second filtrate. The pH value of the second filtrate is adjusted to 1-5, solid matter is precipitated, and then filtered to obtain a first precipitate. The first precipitate is recrystallized to obtain a solid phase Scutellaria baicalensis root extract.

[0053] In the preparation process of the scutellaria root extract, the mass ratio of the scutellaria root powder to water can be 1:8, 1:8.5, 1:9, 1:9.5, 1:10, 1:10.5, 1:11, 1:11.5, 1:12, etc. The temperature for heating the second mixture to reflux is 90°C to 110°C, for example, the temperature for heating the second mixture to reflux is 90°C, 92°C, 95°C, 98°C, 100°C, 102°C, 105°C, 108°C, 110°C, etc. The time for heating the second mixture to reflux can be 1h, 2h, 3h, 4h, 5h, etc. When adjusting the pH value of the second filtrate, the pH value of the second filtrate can be adjusted to 1, 2, 3, 4, 5, etc. When the first precipitate is recrystallized, ethanol can be used to dissolve the first precipitate, and then the pH value of the dissolved solution is adjusted to neutral using an alkaline solution such as a hydroxide solution, and then recrystallized by cooling, precipitating, re-dissolving, and re-precipitating to improve the purity of components such as baicalin.

[0054] In some embodiments, the preparation of the peony root extract comprises the following steps: mixing peony root powder with water to obtain a third mixture, wherein the mass ratio of peony root powder to water is 1: (6-10). The third mixture is heated to reflux for 1h-3h, and then filtered to obtain a third filtrate. Water in the third filtrate is removed to obtain the peony root extract.

[0055] In the process of preparing the peony root extract, the mass ratio of peony root powder to water can be 1:6, 1:7, 1:8, 1:9, 1:10, etc. The temperature for heating the third mixture to reflux is 90°C to 110°C. For example, the temperature for heating the third mixture to reflux is 90°C, 92°C, 95°C, 98°C, 100°C, 102°C, 105°C, 108°C, 110°C, etc. The time for heating the third mixture to reflux can be 1h, 1.5h, 2h, 2.5h, 3h, etc. The water in the third filtrate can be removed by vacuum filtration, spray drying, etc.

[0056] In some embodiments, the preparation of the Ophiopogon japonicus root extract comprises the following steps: mixing the Ophiopogon japonicus root with water to obtain a fourth mixture, wherein the mass ratio of the Ophiopogon japonicus root to the water is 1:(8-12). The fourth mixture is extracted at 80°C-90°C for 1.5h-3h, and then filtered to obtain a fourth filtrate. Water in the fourth filtrate is removed to obtain the Ophiopogon japonicus root extract.

[0057] In the process of preparing the ophiopogon root extract, the mass ratio of ophiopogon root to water can be 1:8, 1:9, 1:10, 1:11, 1:12, etc. The extraction temperature can be 80°C, 81°C, 82°C, 83°C, 84°C, 85°C, 86°C, 87°C, 88°C, 89°C, 90°C, etc. The extraction time can be 1.5h, 2h, 2.5h, 3h, etc. The water in the fourth filtrate can be removed by vacuum filtration, spray drying, etc.

[0058] In some embodiments, the preparation of oat bran extract includes the following steps: mixing oat bran powder with sodium hydroxide solution to obtain a fifth mixture, wherein the mass ratio of oat bran powder to sodium hydroxide solution is 1: (10-15), and the mass concentration of sodium hydroxide in the sodium hydroxide solution is 0.5%-1%. The fourth mixture is leached at 40°C-50°C for 1h-2h, and then filtered to obtain a fifth filtrate. The pH value of the fifth filtrate is adjusted to 6-7, solid matter is precipitated, and then filtered to obtain a second precipitate. The second precipitate is recrystallized to obtain a solid phase oat bran extract.

[0059] In the preparation process of oat bran extract, the mass ratio of oat bran powder to sodium hydroxide solution can be 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, etc. The mass concentration of sodium hydroxide in the sodium hydroxide solution can be 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc. The extraction temperature can be 40°C, 41°C, 42°C, 43°C, 44°C, 45°C, 46°C, 47°C, 48°C, 49°C, 50°C, etc. The extraction time can be 1h, 1.2h, 1.5h, 1.8h, 2h, etc. When adjusting the pH value of the fifth filtrate, the pH value of the fifth filtrate can be adjusted to 6, 6.2, 6.5, 6.8, 7, etc. When the second precipitate is recrystallized, ethanol recrystallization can be used.

[0060] Another embodiment of the present invention provides a cosmetic comprising an anti-allergic soothing composition.

[0061] In some embodiments, the mass percentage of the anti-allergic soothing composition in the cosmetic is 0.5% to 10%. For example, the mass percentage of the anti-allergic soothing composition in the cosmetic can be 0.5%, 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, etc.

[0062] It is understandable that cosmetics also include auxiliary materials, which may include solvents, stabilizers, antioxidants, emulsifiers, thickeners, preservatives, fragrances, and the like.

[0063] It is understandable that the cosmetics may be moisturizing cosmetics, antioxidant cosmetics, skin conditioning cosmetics, whitening cosmetics, anti-inflammatory cosmetics.

[0064] Example 1

[0065] An anti-allergic soothing composition, wherein the mass percentages of the components are: 5% of cactus extract, 3% of scutellaria root extract, 2% of peony root extract, 3.5% of ophiopogon root extract, 3.5% of oat bran extract, 45% of butylene glycol, and the balance is water. The sum of the mass percentages of the components in the anti-allergic soothing composition is 100%.

[0066] In this embodiment, the preparation method of the cactus extract is as follows: cut the cactus into cactus slices with a thickness of 2 cm. Mix the cactus slices with water to obtain a first mixture, wherein the mass ratio of the cactus slices to the water is 1:6. Heat the first mixture at 100° C. for 2 h and then filter to obtain a first filtrate. Remove water from the first filtrate to obtain the cactus extract.

[0067] The preparation method of the scutellaria root extract is as follows: mixing scutellaria root powder with water to obtain a second mixture, wherein the mass ratio of scutellaria root powder to water is 1:10. The second mixture is heated to 100° C. for reflux treatment for 3 hours, and then filtered to obtain a second filtrate. The pH value of the second filtrate is adjusted to 4, solid matter is precipitated, and then filtered to obtain a first precipitate. The first precipitate is recrystallized to obtain a solid phase scutellaria root extract.

[0068] The preparation method of the peony root extract is as follows: mixing peony root powder with water to obtain a third mixture, wherein the mass ratio of peony root powder to water is 1:8. The third mixture is heated to 98° C. and refluxed for 2 hours, and then filtered to obtain a third filtrate. Water in the third filtrate is removed to obtain the peony root extract.

[0069] The preparation method of the ophiopogon root extract is as follows: the ophiopogon root is mixed with water to obtain a fourth mixture, wherein the mass ratio of the ophiopogon root to the water is 1:10. The fourth mixture is extracted at 85° C. for 2 hours, and then filtered to obtain a fourth filtrate. Water in the fourth filtrate is removed to obtain the ophiopogon root extract.

[0070] The preparation method of the oat bran extract is as follows: oat bran powder is mixed with a sodium hydroxide solution to obtain a fifth mixture, wherein the mass ratio of the oat bran powder to the sodium hydroxide solution is 1:12, and the mass concentration of sodium hydroxide in the sodium hydroxide solution is 0.6%. The fourth mixture is leached at 45° C. for 1.5 hours, and then filtered to obtain a fifth filtrate. The pH value of the fifth filtrate is adjusted to 6.5, solid matter is precipitated, and then filtered to obtain a second precipitate. The second precipitate is recrystallized to obtain a solid phase oat bran extract.

[0071] The preparation method of the anti-allergic soothing composition is as follows: respectively obtain cactus extract, scutellaria root extract, peony root extract, ophiopogon root extract, oat bran extract, butylene glycol and water according to their respective mass percentages. Mix butylene glycol and water to obtain a mixed solution. Add cactus extract, scutellaria root extract, peony root extract, ophiopogon root extract and oat bran extract to the mixed solution in sequence, and stir each time adding an extract at 45°C.

[0072] 1. Test the heavy metal risk of the anti-allergic soothing composition in this example.

[0073] (1) According to Chapter 4 Physical and Chemical Testing Methods: 1.3 of the "Technical Specifications for Safety of Cosmetics", the lead content was tested. The test results showed that the lead content in the anti-allergic soothing composition of this embodiment was 0 mg / kg.

[0074] (2) According to Chapter 4 Physical and Chemical Testing Methods: 1.4 of the "Technical Specifications for Safety of Cosmetics", the arsenic content was tested. The test results showed that the arsenic content in the anti-allergic soothing composition of this embodiment was 0 mg / kg.

[0075] (3) According to Chapter 4 Physical and Chemical Testing Methods: 1.2 of the "Technical Specifications for Safety of Cosmetics", the mercury content was tested. The test results showed that the mercury content in the anti-allergic soothing composition of this embodiment was 0 mg / kg.

[0076] (4) According to Chapter 4 Physical and Chemical Testing Methods: 1.5 of the "Technical Specifications for Safety of Cosmetics", the cadmium content was tested. The test results showed that the cadmium content in the anti-allergic soothing composition of this embodiment was 0 mg / kg.

[0077] 2. Test the microbial risk of the anti-allergic soothing composition in this example.

[0078] (1) According to the microbial detection method in Chapter 5 of the "Technical Specifications for Safety of Cosmetics": 2, the total colony count was tested. The test result is: the total colony count in the anti-allergic soothing composition of this embodiment is 2 CFU / mL (limit requirement 0-1000 CFU / mL).

[0079] (2) According to the Microbiological Detection Methods in Chapter 5 of the "Technical Specifications for Safety of Cosmetics": 6, the total number of molds and yeasts was tested. The test results showed that the total number of molds and yeasts in the anti-allergic soothing composition of this embodiment was 0.

[0080] (3) According to the microbial detection method in Chapter 5 of the "Technical Specifications for Safety of Cosmetics": 3, the thermotolerant coliform group was detected. The detection result is: the thermotolerant coliform group in the anti-allergic soothing composition of this embodiment is 0.

[0081] (4) According to the microbial detection method in Chapter 5 of the "Technical Specifications for Safety of Cosmetics": 5, Staphylococcus aureus was detected. The detection result was: the amount of Staphylococcus aureus in the anti-allergic soothing composition of this embodiment was 0.

[0082] (5) According to the microbial detection method in Chapter 5 of the "Technical Specifications for Safety of Cosmetics": 4, Pseudomonas aeruginosa was detected. The detection result was: the amount of Pseudomonas aeruginosa in the anti-allergic soothing composition of this embodiment was 0.

[0083] The anti-allergic soothing composition was added to the cream, and the mass percentage of the anti-allergic soothing composition in the cream was 0.5%. The anti-allergic soothing cream was prepared according to the conventional cream preparation process. 30 volunteers with sensitive skin were selected and used the cream once in the morning and evening for 4 consecutive weeks. The sensitive symptoms of the skin (redness, swelling, itching, and stinging), skin moisture content, and skin barrier function (transepidermal water loss rate) were tested before and after use. The results showed that the facial redness, swelling, itching, and stinging symptoms were significantly alleviated after use, the skin moisture content increased by an average of 20%, and the transepidermal water loss rate decreased by 15%, indicating that the anti-allergic soothing composition can effectively improve the condition of sensitive skin, has good anti-allergic soothing and moisturizing effects, and has no adverse effects on the texture and feel of the cream.

[0084] Examples 2 to 7, Comparative Examples 1 to 6

[0085] Compared with Example 1, the differences between Examples 2 to 7 and Comparative Examples 1 to 6 are shown in Table 1.

[0086] Test Example 1:

[0087] In vitro cell culture experiments were conducted, with human skin keratinocytes (HaCaT) as the research object, and equal amounts of the compositions in the embodiments and comparative examples were added. Lipopolysaccharide (LPS) was used to induce an inflammatory response in HaCaT cells, and the content of inflammatory factors (interleukin-6 (IL-6)) in the cell culture fluid was measured. The results are shown in Table 1.

[0088] Test Example 2:

[0089] The same amount of the composition of the embodiment and the comparative example was applied to the right hind paw of the mouse, and then λ-carrageenan was injected into the sole of the foot to induce edema of the mouse paw. After 24 hours, the thickness of the right hind paw of each group of mice was measured. The smaller the thickness, the more obvious the edema inhibition effect, that is, the better the anti-allergic effect. The thickness of the right hind paw obtained by the test is shown in Table 1.

[0090] Table 1

[0091]

[0092] It can be seen from Table 1 that when the composition further comprises cactus extract, scutellaria root extract, peony root extract, ophiopogon root extract, oat bran extract, butylene glycol and water in an appropriate mass percentage ratio, the composition has a good anti-allergic and soothing effect.

[0093] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

[0094] For those skilled in the art, according to the concept of the present invention, there may be changes in the specific implementation methods and application scopes. In summary, the content of this specification should not be understood as limiting the present invention.

Claims

1. An anti-allergic soothing composition, characterized in that: The invention comprises the following components in percentage by mass: 2% to 8% of cactus extract, 1% to 5% of scutellaria root extract, 0.5% to 3% of peony root extract, 2% to 5% of ophiopogon root extract, 2% to 5% of oat bran extract, 40% to 50% of butylene glycol and the balance of water.

2. The anti-allergic soothing composition according to claim 1, characterized in that: The invention comprises the following components in percentage by mass: 4% to 6% of cactus extract, 2% to 4% of scutellaria root extract, 1% to 2.5% of peony root extract, 2.5% to 4% of ophiopogon root extract, 3% to 4% of oat bran extract, 43% to 48% of butylene glycol and the balance of water.

3. A method for preparing the anti-allergic soothing composition according to any one of claims 1 to 2, characterized in that: The steps include: Obtain the cactus extract, the Scutellaria baicalensis root extract, the Paeonia lactiflora root extract, the Ophiopogon japonicus root extract, the oat bran extract, the butylene glycol and the water according to their respective mass percentages; Mixing the butanediol and the water to obtain a mixed solution; The cactus extract, the Scutellaria baicalensis root extract, the Paeonia lactiflora root extract, the Ophiopogon japonicus root extract and the oat bran extract are sequentially added to the mixed solution, and each time an extract is added, it is stirred evenly at a temperature of 40° C. to 50° C.

4. The method for preparing the anti-allergic soothing composition according to claim 3, characterized in that: The preparation of the cactus extract comprises the following steps: Cut the cactus into cactus slices with a thickness of 0.5 cm to 3 cm; Mixing the cactus flakes with water to obtain a first mixture, wherein the mass ratio of the cactus flakes to water is 1:(5-10); The first mixture is heated under reflux for 1 h to 5 h, and then filtered to obtain a first filtrate; The water in the first filtrate is removed to obtain the cactus extract.

5. The method for preparing the anti-allergic soothing composition according to claim 3, characterized in that: The preparation of the Scutellaria baicalensis root extract comprises the following steps: Mixing the Radix Scutellariae Root powder with water to obtain a second mixture, wherein the mass ratio of the Radix Scutellariae Root powder to water is 1:(8-12); The second mixture is heated under reflux for 1 h to 5 h, and then filtered to obtain a second filtrate; The pH value of the second filtrate is adjusted to 1-5, solid matter is precipitated, and then filtered to obtain a first precipitate; The first precipitate is recrystallized to obtain the Scutellaria baicalensis root extract in a solid phase.

6. The method for preparing the anti-allergic soothing composition according to claim 3, characterized in that: The preparation of the peony root extract comprises the following steps: Mixing peony root powder with water to obtain a third mixture, wherein the mass ratio of the peony root powder to water is 1:(6-10); The third mixture is heated under reflux for 1 h to 3 h, and then filtered to obtain a third filtrate; The water in the third filtrate is removed to obtain the peony root extract.

7. The method for preparing the anti-allergic soothing composition according to claim 3, characterized in that: The preparation of the ophiopogon root extract comprises the following steps: Mixing the root of Ophiopogon japonicus with water to obtain a fourth mixture, wherein the mass ratio of the root of Ophiopogon japonicus to water is 1:(8-12); The fourth mixture is extracted at 80° C. to 90° C. for 1.5 h to 3 h, and then filtered to obtain a fourth filtrate; The water in the fourth filtrate is removed to obtain the Ophiopogon japonicus root extract.

8. The method for preparing the anti-allergic soothing composition according to any one of claims 3 to 7, characterized in that: The preparation of the oat bran extract comprises the following steps: Mixing oat bran powder with sodium hydroxide solution to obtain a fifth mixture, wherein the mass ratio of the oat bran powder to the sodium hydroxide solution is 1:(10-15), and the mass concentration of sodium hydroxide in the sodium hydroxide solution is 0.5%-1%; The fourth mixture is extracted at 40° C. to 50° C. for 1 h to 2 h, and then filtered to obtain a fifth filtrate; The pH value of the fifth filtrate is adjusted to 6-7, solid matter is precipitated, and then filtered to obtain a second precipitate; The second precipitate is recrystallized to obtain the oat bran extract in a solid phase.

9. A cosmetic, characterized in that: The anti-allergic soothing composition comprises the anti-allergic soothing composition according to any one of claims 1 to 2.

10. The cosmetic according to claim 9, characterized in that The mass percentage of the anti-allergic soothing composition in the cosmetic is 0.5% to 10%.

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