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96results about How to "Useful in treating" patented technology

Methods and compositions for determining the efficacy of a treatment for ankylosing spondylitis using biomarkers

The invention provides a method for determining the efficacy of a TNFα inhibitor, such as a TNFα antibody, or an antigen-binding portion thereof, for treating ankylosing spondylitis (AS), using a collagen degradation biomarker and / or a synovitis biomarker.
Owner:AMERICAN TELEPHONE & TELEGRAPH CO +1

Methods and compositions for diagnosing ankylosing spondylitis using biomarkers

ActiveUS20070172897A1Low costBetter assess improvements in the patient's disease statusBioreactor/fermenter combinationsBiological substance pretreatmentsAnkylosing spondylitisAntigen binding
The invention provides a method for determining the efficacy of a TNFα inhibitor, such as a TNFα antibody, or an antigen-binding portion thereof, for treating ankylosing spondylitis (AS), using a collagen degradation biomarker and / or a synovitis biomarker.
Owner:AMERICAN TELEPHONE & TELEGRAPH CO +1

Brine-based viscosified treatment fluids and associated methods

InactiveUS20060014648A1Easy to useExceptional propertyConstructionsFlushingSaline waterMedicine
The present invention relates to viscosified treatment fluids used in industrial and oil field operations, and more particularly, to brine-based viscosified treatment fluids comprising xanthan gelling agents, and their use in industrial and oil field operations. In one embodiment, the present invention provides a method of treating a portion of a subterranean formation comprising the steps of: providing a viscosified treatment fluid that comprises a brine and a gelling agent that comprises a clarified xanthan; and treating the portion of the subterranean formation. The present invention also provides methods of fracturing, gravel packing, and making viscosified treatments fluids. Also provided are viscosified treatment fluid compositions, and gelling agent compositions.
Owner:HALLIBURTON ENERGY SERVICES INC

Protein-active agent conjugates and method for preparing the same

The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates, as well as methods for making the conjugates and compositions. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent).
Owner:LEGOCHEM BIOSCIENCES INC

Pressure sensor for extracorporeal circulating circuit

A pressure sensor for an extracorporeal circulating circuit includes a liquid chamber, a pressure measuring means, and a liquid flow path. The liquid chamber includes a reference surface not deformed by a pressure in the extracorporeal circulating circuit, a deforming surface disposed separated from the reference surface and deformed at least partially by a pressure in the extracorporeal circulating circuit, a first connection surface that joins the deforming surface with the reference surface to form a closed liquid-tight space inside them and is not deformed by a pressure in the extracorporeal circulating circuit, a liquid inflowing port provided in the side surface of the first connection surface, and a liquid outflowing port disposed away by ½ to less than one round from the inflowing port in the flowing direction of liquid introduced along the inner periphery of the side surface of the first connection surface. The pressure measuring means measures the deformation amount of the deforming surface, and is disposed outside the liquid chamber; and the liquid flow path is liquid-tightly connected with the liquid inflowing port so that liquid to be introduced into the liquid chamber flows in along the inner periphery of the side surface of the first connection surface.
Owner:ASAHI KASEI MEDICAL CO LTD

Film forming method and film forming apparatus

On a surface of an object to be treated, a Mn-containing thin film or CuMn-containing alloy thin film is formed by heat treatment (CVD or ALD) by using a Mn-containing source gas (or Mn-containing source gas and a Cu-containing gas) and an oxygen-containing gas (for instance, water vapor) as a processing gas. The Mn-containing thin film or the CuMn-containing alloy thin film can be formed with high step coverage in a fine recess formed on the surface of the object to be treated.
Owner:TOKYO ELECTRON LTD +1

Composition and method for the treatment of carcinoma

The present invention relates to compositions and methods useful for treating a carcinoma or viral infection in mammals, including humans. The methods and compositions typically comprise use of an immunogenic or immunomodulatory compound, and a gamma delta T cell activator, such that the composition is effective for treating a carcinoma or viral infection. In a preferred aspect of the invention, the methods comprise use of a gamma delta T cell activator and a Mycobacterium antigen, which for example is an attenuated strain of Mycobacterium bovis (Bacillus Calmette-Guerin (BCG)).
Owner:ROMAGNE FRANCOIS +1

Film forming method and film forming apparatus

On a surface of an object to be treated, a Mn-containing thin film or CuMn-containing alloy thin film is formed by heat treatment (CVD or ALD) by using a Mn-containing source gas (or Mn-containing source gas and a Cu-containing gas) and an oxygen-containing gas (for instance, water vapor) as a processing gas. The Mn-containing thin film or the CuMn-containing alloy thin film can be formed with high step coverage in a fine recess formed on the surface of the object to be treated.
Owner:TOKYO ELECTRON LTD +1

Monoclonal Antibody Which Specifically Recognizes B Cell Lymphoma and Use Thereof

Provided is a monoclonal antibody which specifically recognizes B cell lymphoma cells and a use thereof. More specifically, provided are the monoclonal antibody; a pharmaceutical composition for preventing or treating B cell lymphoma including the monoclonal antibody; a composition for diagnosing B cell lymphoma including the monoclonal antibody; a method for providing information for diagnosing B cell lymphoma using the monoclonal antibody; a chimeric antigen receptor (CAR) protein including i) the antibody, ii) a transmembrane domain, and iii) an intracellular signaling domain; a recombinant vector which expresses the CAR protein; a CAR-modified T cell transformed with the recombinant vector; a pharmaceutical composition for preventing or treating B cell lymphoma including the CAR-modified T cell; and an antibody-drug conjugate wherein the monoclonal antibody and a drug are conjugated.
Owner:EUTILEX CO LTD

Pressure sensor for extracorporeal circulating circuit

A pressure sensor for an extracorporeal circulating circuit includes a liquid chamber, a pressure measuring means, and a liquid flow path. The liquid chamber includes a reference surface not deformed by a pressure in the extracorporeal circulating circuit, a deforming surface disposed separated from the reference surface and deformed at least partially by a pressure in the extracorporeal circulating circuit, a first connection surface that joins the deforming surface with the reference surface to form a closed liquid-tight space inside them and is not deformed by a pressure in the extracorporeal circulating circuit, a liquid inflowing port provided in the side surface of the first connection surface, and a liquid outflowing port disposed away by ½ to less than one round from the inflowing port in the flowing direction of liquid introduced along the inner periphery of the side surface of the first connection surface. The pressure measuring means measures the deformation amount of the deforming surface, and is disposed outside the liquid chamber; and the liquid flow path is liquid-tightly connected with the liquid inflowing port so that liquid to be introduced into the liquid chamber flows in along the inner periphery of the side surface of the first connection surface.
Owner:ASAHI KASEI MEDICAL CO LTD

Membrane separation of water and fuel from engine oil in an internal combustion engine

Water and fuel contaminating material may be removed from a stream operating engine. A suitable membrane material is supported in a suitable housing. At least a portion of the contaminated oil stream is flowed over one side of the membrane and water and fuel material diffuses through the membrane to its other side where they are gathered and removed from the housing. The water and fuel material may be recovered separately using different membranes or different regions of a membrane. They may be swept from the membrane and housing a flow of air for disposition outside the housing.
Owner:GM GLOBAL TECH OPERATIONS LLC

Massage implement

A massage implement consisting of two elements. One element is a metal tube that receives an adjustable insert therein. The insert and the tube are adjustable in length relative to each other. The metal tube has at its top a T-shaped configuration attached thereto which is made of a hard rubber or plastic material. The sliding insert is made of hard rubber or a plastic material and has a way of arresting the sliding insert therein after a predetermined length has been established. The sliding insert has at its bottom replaceable massaging tools thereon. The different massaging tools are used for treating different areas on the body of a patient. The massage implement is used by a therapist by placing the T-shaped configuration in the area of the armpit and by applying pressure to any of the bottom massage tools. The pressure is applied by the weight of the body of therapist.
Owner:LUND MERRILL A

Bone screw

Bone screws suitable for use with treatment of bones such as phalanges, particularly distal or terminal phalanges, and methods of using the bone screws are disclosed. Exemplary bone screws include a shaft having a thread about at least a portion of the shaft and at least one blade attached to the shaft. The at least one blade can be configured to bury into a bone to capture bone fragments and / or to securely attach to a bone.
Owner:EXSOMED CORP

Amino acid-conjugated cyanoacrylate polymer particles

Disclosed are cyanoacrylate polymer particles which comprise an amino acid(s) and have an average particle diameter of less than 1000 nm. The amino acid-containing particles according to the present invention can kill cancer cells by inducing apoptosis-like cell death. The particles have an especially high affinity for cell lines derived from lymphomas such as T-cell lymphoma and B-cell lymphoma. The particles can also exhibit an antiproliferative effect against some kinds of pancreatic cancer-derived cell lines. Therefore, the particles according to the present invention are useful for prevention and / or treatment of cancers.
Owner:PUBLIC UNIV CORP YOKOHAMA CITY UNIV

Antibody-active agent conjugates and methods of use

The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent).
Owner:LEGOCHEM BIOSCIENCES INC

Tagged Polymers, Water Treatment Compositions, And Methods Of Their Use In Aqueous Systems

A method and composition is described for controlling the growth of fouling materials, such as scale, in aqueous systems using a tagged (fluorescent) polymer. The tagged polymer can be a fluorescent polymer which has at least one fluorescent monomeric unit derived from a fluorophore which has at least one terminal end comprising an olefinic group. The method of controlling the growth of at least one fouling material in an aqueous system can include the steps of adding the tagged polymer to the aqueous system to be treated, fluorometrically monitoring the concentration of the tagged polymer, and adjusting, as needed, the concentration of the tagged polymer and proportionally used water treatment compound or compounds effective to control the growth of at least one fouling material. The adjustment of pH before determination of the fluorescence signal can be employed to increase sensitivity of the fluorophore and minimize background interference.
Owner:BUCKMAN LAB INT INC

Shoe and shoeing method

A shoe for a hoofed animal, e.g. a horseshoe, is described which comprises a body made from a thermoplastic composition which comprises a matrix of a thermoplastic material which has a softening point of less than 100° C., such as a polycaprolactone. A method of shoeing a hoofed animal, such as a horse, is also described.
Owner:POYNTON ANDREW PAUL

Tinnitus testing device using brain waves and tinnitus testing method using same

The tinnitus testing apparatus of this invention comprises a control part that in turn comprises: an auditory stimulus generation part that can generate a stimulus; and an AEP acquisition and amplitude measurement part that can acquire auditory evoked potential (AEP) brain waves of a examinee due to said stimulus and measure the specific amplitude of said acquired brainwaves; wherein said auditory stimulus is one or more of: a 1st stimulus containing continuous noise and pulse noise; and a 2nd stimulus containing pulse noise and continuous noise with a silent gap.
Owner:IND ACADEMIC CORP FOUND YONSEI UNIV

Ozonized Surfactant

InactiveUS20100041903A1Same level of bactericidal and deodorizing abilityStrong bactericidal abilityAntibacterial agentsCosmetic preparationsDouble bondAlkene
Disclosed herein is an ozonized surfactant which has the same level of bactericidal and deodorizing abilities as that of ozonized olive oil and which can be evenly applied or sprayed onto and can permeate any place or environment (a highly hydrophilic or hydrophobic place or environment). The ozonized surfactant can be obtained by adding ozone to a surfactant having at least one olefin-based double bond in a hydrophobic group moiety.
Owner:ERC TECH

Method for determining a patient specific locally varying margin

It is an object of the invention to provide for an improved radiation treatment. According to a first aspect of the invention, this object is achieved by a method for determining a patient specific locally varying margin on a treatment target and / or an organ at risk in order to compensate for local intrafraction motion expected during a radiotherapy fraction to be delivered over a radiotherapy fraction time interval. The patient specific locally varying margin is determined based on a displacement and / or an estimate of the displacement of at least a first location and a second location on the treatment target and / or organ at risk. The method comprises steps of: acquiring a first medical image of the treatment target and / or the organ at risk and acquiring a second medical image of the treatment target and / or the organ at risk, wherein the time between the acquisition of the first medical image and the second medical image is similar to the radiotherapy fraction time interval and determining of positions of the first location and the second location in the first medical image and in the second medical image and using the determined positions for determining the patient specific locally varying margin around the treatment target and / or organ at risk.
Owner:KONINKLJIJKE PHILIPS NV

Agent Comprising Fgf2 as an Effective Ingredient For Treatment or Prevention of Asthma and Chronic Obstructive Pulmonary Disease

The present invention relates an agent comprising FGF2 (Fibroblast Growth Factor-2 or basic Fibroblast Growth Factor(bFGF)) as an effective ingredient for treatment or prevention of Asthma and Chronic Obstructive Pulmonary Disease(COPD). Also, The present invention relates Th1 asthma and COPD mouse animal model induced by Ovalbumin and double strand RNA. The therapeutic agent comprising FGF2 of the present invention can be used for treatment or prevention for airway fibrosis, airway inflammation, airway hyperresponsiveness, airway remodeling, asthma and COPD. Also, Th1 asthma and COPD mice animal model induced by Ovalbumin and double strand RNA can be used for development of therapeutic agent for asthma and COPD.
Owner:MD HEALTHCARE INC

Resonant transducer and ultrasonic treatment device including resonant transducer

A resonant transducer comprising:a vibration plate; anda piezoelectric element including a piezoelectric film and an upper electrode,wherein a difference between a Young's modulus of the vibration plate and a Young's modulus of the piezoelectric film is not more than 20% with respect to the Young's modulus of the vibration plate.
Owner:FUJIFILM CORP
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