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11 results about "Methylglyoxal" patented technology

Methylglyoxal (MGO) is the organic compound with the formula CH₃C(O)CHO. It is a reduced derivative of pyruvic acid. It is a reactive compound that is implicated in the biology of diabetes. Methylglyoxal is produced industrially by degradation of carbohydrates using overexpressed methylglyoxal synthase.

Beer-taste alcoholic beverage and production method therefor

PCT designated stageWO2025258583A1Beer brewingBiotechnologyAlcohol drink
The purpose of the present invention is to provide a beer-taste alcoholic beverage having a rich flavor, a favorable aftertaste, and a favorable amount of flavor. The present invention provides: a beer-taste alcoholic beverage in which the total concentration of free carboxymethyllysine (CML), free carboxyethyllysine (CEL), and free methylglyoxal-derived hydroimidazolone-1 (MG-H1) is 280-1,400 ppb; and a beer-taste alcoholic beverage in which the total concentration of free CML, free CEL, and free MG-H1 is 280-1,600 ppb, the total concentration of bound CML, bound CEL, and bound MG-H1 is 150-900 ppb, and the bound CML, the bound CEL, and the bound MG-H1 are included in a peptide fraction having a molecular weight of 1,060-3,080 Da (gel filtration method for HPLC analysis).
Owner:KIRIN HOLDINGS KK

Beer-flavored beverage and method for manufacturing same

PCT designated stageWO2025258585A1Beer brewingFood scienceBiotechnologyMethyl glyoxal
The purpose of the present invention is to provide a beer-flavored beverage that has rich taste and delivers refreshing stimulation. The present invention provides a beer-flavored beverage in which: the total concentration of free carboxymethyllysine (CML), free carboxyethyllysine (CEL), and free methylglyoxal-derived hydroimidazolone-1 (MG-H1) is 200 ppb to 1,750 ppb; the total concentration of bound CML, bound CEL, and bound MG-H1 is 33 ppb to 160 ppb; and the bound CML, bound CEL, and bound MG-H1 are contained in a peptide fraction having a molecular weight of 35–50 kDa.
Owner:KIRIN HOLDINGS KK

Beer-flavor alcoholic beverage and preparation method thereof

Disclosed is a beer-taste alcoholic beverage in which the total content of free carboxy methyl lysine (CML), free carboxy ethyl lysine (CEL), and free methylglyoxal-derived hydroimidazolione-1 (MG-H1) in the beverage is 600-1500 ppb, the total content of bound CML, bound CEL, and bound MG-H1 in the beverage is 90-349 ppb, the bitter taste value is 20 or more, and the content of the bound CML, bound CEL, and bound MG-H1 in the beverage is 90-349 ppb. In the beer-taste alcoholic beverage, the binding type CML, the binding type CEL, and the binding type MG-H1 are included in a peptide fraction having a molecular weight of 400-3000 Da. In the beer-flavored alcoholic beverage, unpleasant bitter taste is relieved.
Owner:KIRIN HOLDINGS KK

Alcohol-free beer-taste beverage with enhanced mellowness

PendingCN121969242Aincrease bodyEnhance grain feelFood ingredient as flavour affecting agentBiotechnologyMethyl glyoxal
Disclosed is a non-alcoholic beer-taste beverage in which the total content of free carboxy methyl lysine (CML), free carboxy ethyl lysine (CEL), and hydroimidazolione-1 (MG-H1) derived from free methylglyoxal in the beverage is 160 ppb or more. The mellow feeling of the non-alcoholic beer-taste beverage is enhanced.
Owner:KIRIN HOLDINGS KK

Bifunctional carbon-based catalyst and use thereof

The application discloses a kind of bifunctional carbon-based catalyst and its application, the bifunctional carbon-based catalyst of the particle size 1nm-7 μm boron-carbon-based microspheres, with furan boronic acid and methylglyoxal as raw material to prepare by hydrothermal co-carbonization reaction.It is with methylglyoxal and furan boronic acid mixture as composite functional carbon source, by one-step hydrothermal co-carbonization method synthesized with strong adsorption boron hydroxyl and in-situ carboxyl bifunctional carbon-based catalyst.Boron hydroxyl is adsorption site, by with cellulose form chemical bond force to improve the mass transfer efficiency of catalyst and cellulose;With in-situ carboxyl as catalytic site, break glycosidic bond, can realize cellulose to glucose efficient conversion in pure aqueous phase.In addition, the bifunctional carbon-based catalyst of the application has excellent hydrothermal stability and repeatability in catalyzing cellulose conversion, solvent system is water, more economical, green, safe.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI

Process for the production of 2-acetylpyrroline

PendingCN122102996AOrganic chemistryEnzymesPyrroline Carboxylate ReductasesCarboxyl radical
The present application provides a method of producing 2-acetylpyrroline, comprising reacting 2-carboxypyrrline with methylglyoxal. The present application also provides a polypeptide comprising an amino acid sequence set forth in SEQ ID NO: 1 or a functional variant thereof, wherein the functional variant has delta(1)-pyrroline-2-carboxylate reductase activity. The present application also provides a method of producing 2-carboxypyrrline, comprising contacting the polypeptide with proline.
Owner:TIANJIN UNIV

Methyl glyoxal preparation device and method

The invention relates to a methyl glyoxal preparation device and method. The device comprises a supply system and a reaction flow pipe system, wherein the supply system is connected with the reaction flow pipe system; the supply system comprises a chlorine supply module, a hydroxyacetone supply module and an oxygen supply module; the reaction flow pipe system comprises a reaction flow pipe, and the reaction flow pipe comprises a first connecting section, a second connecting section and a third connecting section; a photolysis module is arranged on the periphery of the first connecting section and comprises a light source assembly and a light reflection enhancing assembly. The light reflection enhancing assembly is arranged on the light propagation path; the chlorine supply module is connected with the first connecting section, the hydroxyacetone supply module is connected with the second connecting section, and the oxygen supply module is connected with the third connecting section. The device is simple and convenient to operate and mild in reaction condition, continuous flow synthesis can be realized, and the reaction efficiency and the product yield are remarkably improved.
Owner:SUZHOU UNIV OF SCI & TECH

Method for continuous preparation of methylglyoxal based on gas phase oxidation of glycerol

The application relates to a method for continuously preparing methylglyoxal based on a glycerol gas-phase oxidation reaction, which comprises the following steps: subjecting pure glycerol or a glycerol solution to vaporization treatment to form raw material vapor; mixing the raw material vapor with O2-containing gas to form mixed gas; and contacting the mixed gas with a supported nanometer gold catalyst to generate selective oxidation reaction to form methylglyoxal, wherein the carrier of the supported nanometer gold catalyst is a metal oxide.
Owner:TSINGHUA UNIVERSITY

Fluorescent probe for recognizing methylglyoxal as well as preparation method and application of fluorescent probe

The invention discloses a fluorescent probe for recognizing methylglyoxal as well as a preparation method and application of the fluorescent probe, and belongs to the technical field of chemical analysis and detection. The structural formula of the fluorescent probe for identifying methylglyoxal is shown in the specification. In addition, the invention also provides a preparation method of the fluorescent probe. In addition, the invention also provides an application of the fluorescent probe or the fluorescent probe prepared by the preparation method in detection of methylglyoxal in an environment or a biological sample. The fluorescent probe provided by the invention can be used for detecting methylglyoxal in living cells and zebra fish, and can realize distribution imaging and detection of MGO in an arabidopsis thaliana living body in a lossless manner.
Owner:WUHAN INST OF TECH

A composition for preventing and treating chestnut internal rot and improving drought resistance and application thereof

PendingCN122350092ABiotechnologyAzoxystrobin
This invention relates to a composition for preventing and controlling internal rot in chestnuts and enhancing drought resistance, and its application, belonging to the field of pest and disease control technology. This invention provides a composition for preventing and controlling internal rot in chestnuts, comprising azoxystrobin, aminoethyl ester, calcium nitrate, gibberellin, methylglyoxal, a compound essential oil, and water. In this composition, aminoethyl ester and calcium nitrate work synergistically to further accelerate the penetration effect of azoxystrobin. The compound essential oil is formulated to target specific pathogens of internal rot, and together with azoxystrobin, it can eliminate pathogens of internal rot and also has a water-retaining effect. The addition of methylglyoxal can alleviate oxidative damage caused by drought stress. Spraying the composition of this application during the peak flowering period of chestnuts not only has a significant control effect on internal rot in chestnuts but also improves the drought resistance of chestnut trees.
Owner:SHANDONG INST OF POMOLOGY

Beer-flavor alcoholic beverage and manufacturing method thereof

PendingCN121420052ABeer fermentationBiotechnologyEthyl lysine
Disclosed is a low-sugar beer-flavor alcoholic beverage in which the total content of free carboxy methyl lysine (CML), free carboxy ethyl lysine (CEL), and hydroimidazolione-1 (MG-H1) derived from free methylglyoxal in the beverage is 434 ppb or more. The mellow feeling of the low-sugar beer-flavor alcoholic beverage is enhanced.
Owner:KIRIN HOLDINGS KK