162 results about "Gallocatechin gallate" patented technology

The present invention provides a safe and highly effective antibacterial composition without impairing the flavor of foods or drinks, which composition is used in products such as foods and oral care goods which are mainly to be taken into human or animal bodies or mainly to be used in the oral cavity.

The composition according to the present invention contains gallocatechin gallate as an agent for enhancing the activity of antibacterial catechins in which the antibacterial activity of the antibacterial catechins against Streptococcus mutans is particularly enhanced. The composition according to the present invention can be produced by mixing the antibacterial catechins with gallocatechin gallate. Alternatively, it can be produced as a composition comprising a synthetic adsorbent-adsorbed fraction as the main component, which is obtained by subjecting a solvent-extract from tea leaves to an adsorption treatment with the use of a synthetic adsorbent selected from among aromatic compound-based synthetic adsorbents and methacrylic compound-based synthetic adsorbents.

The disclosure provides compositions treating traumatic brain injuries such as concussions. In one embodiment, the composition comprises phosphatidylserine, phosphatidylcholine, quercetin, astaxanthin, R-alpha lipoic acid, N-acetyl cysteine, taurine, L-glutamine, carnitine, D-ribose, creatine, epigallocatechin gallate, melatonin, ginkgo leaf extract, curcumin and L-glycine. The disclosure also provides methods for treating traumatic brain injuries such as concussions by administering an effective amount of the compositions described within.

The invention discloses a method for identifying the quality of Biluochun tea, which comprises the following steps of: after soaking the Biluochun tea, scanning the soaked solution by using an ultraviolet and visible spectrophotometer; and, after leaching and extracting another Biluochun tea, measuring the contents of epigallocatechin, epigallocatechin epicatechol gallate, epicatechin and epicatechin epicatechol gallate in the tea from the leached and extracted solution by adopting a high efficiency liquid chromatography. According to the method disclosed by the invention, a technology for identifying the quality of the Biluochun tea is established by adopting (a technology that spectrum and chromatograph are combined) spectrum and chromatograph analysis; the comprehensive evaluation data of green tea quality is provided; the method has the characteristics of being accurate, reliable, simple, convenient and efficient; and the method can be popularized and applied in the field of the green tea quality counterfeit identifying technology.

The invention belongs to the fields of medicine and gene engineering, relates to a new medicinal application of epigallocatechin-3-gallate EGCG, and particularly relates to an application of epigallocatechin-3-gallate in the preparation of antitumor drugs. Cell experiments demonstrate that the epigallocatechin-3-gallate is a CYPJ inhibitor, and has the capability of inhibiting liver cancer cell growth; a large dose of EGCG basically has no toxicity to liver, kidney and heart. Experiment results also show that when EGCG is added into a culture solution of tumor cells, the proliferation of tumor cells is inhibited; the tumor cells are blocked at the G1 stage; the activity of CYPJ is inhibited; the activation of an Erk signal path by CYPJ protein is blocked. The epigallocatechin-3-gallate of the invention can be used for the preparation of antitumor drugs, especially anti-liver cancer drugs; and the drugs are designed aiming at cell target points, and drug resistance is not easy to generate.

The present invention is a natural formulation for treatment of male, female and adolescent pattern hair loss. The formulation contains a combination of Green Tea leaf extract, Polyphenols, Epigallocatechin Gallate (EGCG), Vitamin E, Folic Acid, Copper (as Amino Acid Chelate), B12, Zinc (as Oxide), Calcium Pantothenate, Niacin, Biotin, Riboflavin, Thiamine, and optionally Inositol, Black Tea Extract and Nettle Extract. The various extracts are prepared according to traditional procedures, and then combined in a suitable formulation for administration to the patient for treatment of male, female and adolescent pattern hair loss.

With the object of providing a bottleable green tea beverage for selling hot, a bottleable green tea beverage was prepared, which is a bottleable green tea beverage containing a green tea extract obtained by extracting green tea leaves, wherein the content in epigallocatechin gallate and gallocatechin gallate is 380 mg/l to 1500 mg/l as a total value, the content of glutamic acid is 20 mg/l to 120 mg/l, the diff-use transmittance is 1.0% or less, and the pH is 5 to 7.

A purified green tea extract is improved in bitterness and aftertaste.

The purified green tea extract, which comprises satisfying the following conditions:

• • (1) a ratio of a sum of content weights of (A) myricetin, (B) quercetin and (C) kaempferol to a sum of content weights of (D) epigallocatechin gallate and (E) gallocatechingallate, ((A)+(B)+(C))/((D)+(E)), is from 0.0000001 to 0.010,
  • (2) a sum of content weights of (D) the epigallocatechin gallate and (E) the gallocatechin gallate in non-polymer catechins, ((D)+(E))), is from 0.01 to 29 wt %, and
  • (3) a percentage of gallate body in the non-polymer catechins is from 0.01 to 49 wt %.

Disclosed herein are green tea plant material extracts, and methods of using the extracts, comprising at least one green tea catechin selected from the group consisting of epi-gallocatechin, catechin, epicatechin, epigallocatechin-3-gallate, gallocatechin gallate, epicatechin-3-gallate, catechin gallate, and gallocatechin, wherein the compositions of the disclosure provide greater bioavailability of at least one green tea catechin.

A dietary supplement in capsule or tablet form includes a source of zinc in an amount equivalent to 6 mg to 40 mg of zinc chloride; optionally a source of chromium in an amount equivalent to 100 micrograms to 1000 micrograms of chromium picolinate; optionally from 4 micrograms to 100 micrograms of Vitamin B12; optionally an extract or powdered form of American Ginseng in an amount that provides from 20 mg to 200 mg of ginsenoside(s), or 20 mg to 200 mg of isolated or synthesized ginsenoside(s); optionally an oil, extract or powdered form of cinnamon bark in an amount that provides 1000 mg to 5000 mg of methylhydroxychalcone polymer; optionally 2 mg to 50 mg lutein; and optionally green tea extract in an amount that provides from 200 mg to 4000 mg of epigallocatechin gallate or 200 mg to 4000 mg of isolated or synthesized epigallocatechin gallate.

The invention discloses an anti-saccharification composition and a preparation method thereof. The composition specifically comprises the following components in parts by weight: 1%-30% of apples, 1%-25% of red pomegranate, 0.5%-20% of herba lophatheri powder, 0.5%-20% of skipjack tuna oligopeptide, 0.5%-20% of grapes, 0.5%-10% of blackcurrants, 0.1%-10% of mulberries, 0.1%-10% of kudzuvine roots,0.1%-10% of sea buckthorn, 0.1%-10% of black raw ginger, 0.01%-5% of epigallocatechin gallate, and the balance of auxiliary materials. The composition can be used to prepare tablets, granules, capsules, soft capsules, powder or oral liquid and other dosage forms. Functional compounds, functional foods and traditional Chinese medicines are combined, on the basis of the metabolic mechanism of the human body, all-around saccharification resistance is achieved, and meanwhile the effects of oxidation resistance, aging resistance, inflammation resistance, whitening and the like are achieved.

The invention discloses a preparation method of nano-epigallocatechin gallate (EGCG). The preparation method comprises the following steps of step one, weighing certain mass of chitosan and adding into a 1 percent glacial acetic acid solution, heating, stirring for dissolving to obtain a chitosan solution; filtering while hot to obtain a solution A; step two, weighing certain mass of EGCG and adding into the solution A to obtain a solution B; step three, slowly adding a sodium tripolyphosphate solution C into the solution B, and carrying out high-speed stirring while adding to obtain nano EGCGsuspension; step four, adding 2 percent mannitol serving as a freeze-drying protective additive into the nano EGCG suspension, uniformly mixing and carrying out freeze drying to obtain a nano EGCG lyophilized product. The EGCG nanoparticles prepared by the preparation method disclosed by invention have the characteristics of good biocompatibility, biodegradation and the like; in addition, slow release of the EGCG can be effectively restricted, the action time in vivo is prolonged and further the bioavailability of the EGCG is played more fully.

The invention relates to an epigallocatechin gallate-loaded folate-targeted carrier, which is prepared from zeolite imidazole skeleton, epigallocatechin gallate embedded in the zeolite imidazole skeleton, and folic acid-polyethylene glycol modified on the zeolite imidazole skeleton by means of an amido bond. The invention also relates to a preparation method and application of the epigallocatechingallate-loaded folate-targeted carrier. The folate-targeted carrier enhances the antioxidant effect of the epigallocatechin gallate, not only solves the problem of low utilization rate of the tea polyphenol epigallocatechin gallate, but also reduces the toxic and side effects of cancer treatment, and enables medical therapy to have targeting ability.

The invention discloses a method for separating and purifying epigallo catechin gallate (EGCG) by using a simulated moving bed (SMB) chromatography. The method is characterized in that: a tea leaf extract, which is tea polyphenol, is adopted as a raw material; EGCG is separated and purified by using an SMB chromatography system. According to the method, fundamental zones of the SMB are set as an eluting zone, a refining zone and an absorbing zone. The eluting zone is independent. Octadecylsilane chemically bonded silica ODS is adopted as a stationary phase, a mixed solution of alcohol and water is adopted as a mobile phase, and SMB separation are carried out two times upon a tea polyphenol raw material liquid, wherein one time is for removing impurities which are hard to elute, and the other time is for removing impurities which are easy to elute. The product is processed through a solvent removing process, such that the EGCG product is obtained. With the method, EGCG can be stably, continuously, and automatically purified from tea polyphenol in large scale, and with high efficiency. The recycling rate of the product is above 94%, and the purity of the product is above 96%. According to the invention, the stationary phase and the mobile phase can be repeatedly utilized, such that the cost is reduced. The invention belongs to green and environment-friendly separation engineering.