32 results about "Gold salts" patented technology

The present invention provides a homocysteine ​​electrochemical sensor, and its preparation method and application. The preparation method of the homocysteine ​​electrochemical sensor of the present invention comprises the following steps: adding a dispersion containing carbon nanomaterials to the surface of a glassy carbon electrode, baking and drying, to obtain a carbon nanomaterial-modified electrode; then placing the carbon nanomaterial-modified electrode in a gold salt aqueous solution, and using an electroplating method to deposit nanogold on the surface of the carbon nanomaterial-modified electrode, to obtain a homocysteine ​​electrochemical sensor; the high conductivity of gold nanoparticles is of great significance for improving the electrocatalytic performance of the composite material for homocysteine. The homocysteine ​​electrochemical sensor prepared by the present application has low cost, low detection limit, and good stability. In addition, the spiked recovery rate of homocysteine ​​in serum samples is good, which provides potential application value for the reliable determination of homocysteine ​​in biological systems and the study of homocysteine-related diseases.

The invention relates to preparation and application of a nano material for targeting and enhancing nervous tumor ferroptosis, and belongs to the field of medicines. The nano-scale polypeptide-gold complex cluster NG formed by gold and sulfydryl-containing targeting polypeptide is characterized in that NG molecules form AuxPy, x is equal to 1-35, y is equal to 1-30, and P is corresponding nervous system tumor targeting polypeptide, preferably Au17P7. The preparation method comprises the following steps: mixing a gold salt solution with nervous system tumor targeting polypeptide to form a mixed solution, and adding a reducing agent under certain temperature and pH conditions, so that Au interacts with a sulfydryl phase of the polypeptide to form the complex cluster NG. The compound is used for preparing a targeted drug for improving the tumor treatment effect of the ferroptosis inducer, and has a specific synergistic treatment effect on nervous system tumors when being used together with the ferroptosis inducer.

The invention relates to the technical field of electroplating, and particularly discloses a cyanide-free gold electroplating solution as well as a preparation method and application thereof. The cyanide-free electrogilding plating solution comprises soluble gold salt, a first complexing agent, a second complexing agent, a buffering agent, a brightening agent, a wetting agent, a titanium ion chelating agent, an antioxidant, conducting salt and the balance deionized water. The first complexing agent is ethylene diamine tetraacetic acid disodium salt; the preparation raw materials of the second complexing agent comprise an aza-macrocyclic complex and sodium hydroxide, and the mass ratio of the aza-macrocyclic complex to the sodium hydroxide is 1: (1-2). The stability of the plating solution can be improved, and a plating layer with fine crystal nucleus and a compact structure can be formed, so that the protection performance and the appearance of the plating layer are improved.

The disclosed subject matter relates to gold particles, and methods of making and use thereof. For example, disclosed herein are one-step ligand exchange methods. The methods comprise contacting a gold particle capped with a toxic ligand with a less-toxic ligand in a solution, wherein the concentration of the less-toxic ligand and / or the pH is sufficient to cause the toxic ligand to be replaced by the less-toxic ligand. In some examples, the methods comprise contacting a gold particle capped with a toxic ligand with a gold salt and a less-toxic ligand in a solution, wherein the less-toxic ligand is a reducing agent for the gold salt, such that the gold salt is reduced and deposited as a thin layer of gold onto the gold particle, wherein the concentration of the less-toxic ligand is sufficient to cause the toxic ligand to be replaced by the less-toxic

The invention discloses preparation and application of a gold cluster compound for targeted therapy of acute kidney injury diseases, and relates to the field of nephropathy treatment medicines. The molecular composition (Au) is x (S) y, x is equal to 3-144, y is equal to 1-140, and S is a sulfydryl-containing renal injury target protein binding peptide or a sulfydryl-modified renal injury target protein binding peptide. The method comprises the following steps: mixing a gold salt solution with a sulfydryl-containing ligand to form a mixed solution; under the conditions of certain temperature and pH, the mixed solution system is subjected to a reduction reaction, high-valence Au ions in the gold salt are reduced into Au atoms or monovalent Au ions, and Au forms a gold cluster compound through physical or chemical interaction; the cluster compound disclosed by the invention has remarkable treatment activity in a cis-platinum induced acute kidney injury model, and the acute kidney injury is treated in a targeted manner by inhibiting over transcription and expression of pro-inflammatory cytokines and removing reactive oxygen species (ROS).

The invention relates to the technical field of surface treatment, and discloses a gold plating solution, a preparation method thereof and an electroplating process. According to the total volume of the gold plating solution, the gold plating solution comprises the following components by concentration: 1-20 g / L of gold salt; 100 to 230 g / L of citrate; 20 to 50g / L of oxalate; 0.5-5 g / L of a transition metal additive; 4-10 g / L of an antioxidant; 1-5 g / L of a surfactant; wherein the pH value of the gold plating solution is 4-4.8, and the specific gravity of the gold plating solution is 10-15; the citrate comprises potassium citrate and citric acid; the transition metal additive is selected from at least one of cobalt salt, nickel salt and ferric salt. The preparation method is simple, and the prepared gold plating solution is used for the steps of base material pretreatment, electroplating treatment and aftertreatment in the electroplating process, so that the prepared gold plating product has excellent binding force, wear resistance, corrosion resistance and the like.

A cancer therapeutic agent includes a caffeic acid or cadambine phytochemicals cocktail on surfaces of gold nanoparticles. The agent can include a caffeic acid and cadambine phytochemicals cocktail on the surfaces of the gold nanoparticles. The surfaces are preferably stabilized with gum Arabic. The surfaces can consist of caffeic acid stabilized with gum Arabic, cadambine stabilized with gum Arabic, or caffeic acid and cadambine stabilized with gum Arabic. A method of forming the agents uses electrons of caffeic acid and / or cadambine to reduce gold salt(s) to gold nanoparticles without the use of any external toxic chemical reducing agents.

The present invention provides a method for preparing a palladium-gold solid solution, comprising the following steps: S1) Mixing a palladium salt and a gold salt in water to obtain a first mixed solution; mixing an organic monomer and water to obtain a second mixed solution; S2) Adding an organic buffer to the first mixed solution, adjusting the pH value to alkaline, then adding the second mixed solution, and continuously stirring to obtain a precursor; S3) Annealing the precursor in a protective atmosphere to obtain a palladium-gold solid solution. Compared with the prior art, the present invention uses an organic monomer to polymerize and coat palladium-gold ion clusters under alkaline conditions, and a palladium-gold solid solution can be obtained after annealing treatment, providing the uniformity of the gold phase structure distribution in the solid solution. As a catalyst, it has high electrocatalytic oxygen reduction activity, and this preparation method is safe and easy to implement, without generating additional toxic by-products, and the required equipment is simple. It is a method for large-scale preparation of palladium-gold solid solution catalysts.

A process for preparing a catalyst for the oxidative esterification of methacrolein to methyl methacrylate includes providing a support selected from an oxide of silicon, a carbide of silicon, a metal oxide, and a metal carbide. Particles of at least one oxide of a metal are provided on the support. The support is contacted with a gold salt and heated at a temperature ranging from 50°C to 600°C for a time ranging from at least 0.1 hours to 48 hours to convert the gold salt into gold nanoparticles having an average diameter of less than 12 nm and a standard deviation of + / - 4 nm, with at least 75% by number of the gold nanoparticles located within 20 nm of the metal oxide particle.

The present application relates to a preparation method of gold-plated nickel powder, which provides a fourth mixed solution formed by mixing a gold salt, a weak acid solution and a volatile prevention additive or formed by mixing a cyanide-free gold salt and a weak acid solution, and adds the fourth nickel powder after oil removal by an alkaline solution, pickling and surface activation treatment into the fourth mixed solution to form a fifth mixed solution; the fifth mixed solution is subjected to warming and ultrasonic stirring, and the fifth mixed solution after warming and ultrasonic stirring is subjected to filtration separation to obtain the fifth nickel powder containing gold on the surface; the fifth nickel powder containing gold on the surface is subjected to cleaning and drying to obtain the gold-plated nickel powder. The present application adopts the method of adding a volatile prevention additive or using a cyanide-free gold salt for gold plating, which can effectively inhibit the volatilization of cyanide and is environmentally friendly and safe.

This invention discloses a composite stabilizer for stabilizing volatile heavy metals in the digestion of excess activated sludge and its application method, belonging to the field of environmental monitoring and chemical analysis technology. Addressing the problem that excess sludge from metallurgical wastewater treatment is complex in composition and subject to severe interference, especially the easy loss of volatile elements such as mercury, arsenic, selenium, and antimony during traditional digestion and pretreatment processes, leading to low detection results, this invention provides a solution for stabilizing volatile heavy metals in the digestion of excess activated sludge, enabling accurate detection of these elements. The composite stabilizer efficiently complexes and stabilizes multiple volatile heavy metal elements, overcoming the problems of narrow stability range and high cost associated with single stabilizers (such as gold salts). The combination of L-cysteine ​​and trace amounts of gold salt reduces costs and improves stabilization effect. The use of a low-concentration nitric acid medium avoids interference from chloride ions in hydrochloric acid on arsenic, facilitating accurate detection by mass spectrometry.

The invention relates to a cyanide-free chemical displacement gold plating solution and a gold plating method, which are particularly suitable for deposition of an ultrathin gold layer (less than or equal to 0.1 mu m) on the surface of a nickel base material. The gold plating solution comprises a buffering agent, gold salt and a double-complexing-agent system composed of L-glutamine and 2-furancarboxylic acid. Amido and amino of L-glutamine synergistically act on the surface of nickel, so that mild activation is realized; furan epoxy atoms in 2-furancarboxylic acid and carboxyl form a steric-hindrance effect, so that gold ion release kinetics is regulated and controlled, and excessive substitution reaction is inhibited. The two synergistically solve the problems of unstable gold plating liquid, uneven coverage and the like in replacement gold plating on the nickel layer, and the obtained gold layer is compact and non-porous, and the gold plating liquid is stable. The process is environment-friendly and is suitable for high-reliability gold plating of the microelectronic packaging nickel substrate.

This invention relates to the field of electroplating technology, and discloses an electroplating gold solution, its preparation method, and its application. The electroplating gold solution, by concentration, comprises the following components: 3-15 g / L gold salt, 30-100 mg / L accelerator, 10-20 g / L complexing agent, 15-50 mg / L stabilizer, 10-50 mg / L inhibitor, 30-70 mg / L dispersant, and 10-20 g / L conductive salt; the solvent of the electroplating gold solution is water; the accelerator includes 3-amino-6-methylpyridazine. The electroplating gold solution provided by this invention, using 3-amino-6-methylpyridazine as an accelerator, can promote gold ion precipitation and improve electroplating efficiency; the electroplating gold solution does not use cyanide-containing raw materials, thus having good environmental friendliness; the electroplating gold solution has good stability and a low scrap rate, which helps to save costs; the composition and working parameters of the electroplating gold solution are reasonable, and it can form a uniform, bright coating without plating cracks, and can be applied to the electroplating gold surface treatment of ceramic substrates.

The application discloses a kind of for methanol and methyl methacrolein oxidation esterification catalyst and its preparation method and application, belong to catalytic synthesis technical field.The application first prepares silicon-titanium molecular sieve TS-1 carrier, then loads gold nanoparticles, and gold-based catalyst is prepared, TS-1 carrier can not only stabilize gold salt, Ti-O-Au bond can be formed between titanium species in TS-1 carrier and gold nanoparticles, improve the interaction between gold metal and carrier, more effectively limit the size of gold particle, form smaller size nano gold particle and good dispersity, improve the specific surface area of catalyst, to improve catalyst activity and stability.Mass concentration is 45-80% methanol and methyl methacrolein mixed solution and the obtained catalyst are mixed sufficiently, oxygen is input, and oxidation esterification reaction occurs under 70-160 DEG C, 0.5-2MPa, to prepare methyl methacrylate.The gold-based catalyst prepared by the application significantly improves the conversion rate of methyl methacrolein and the selectivity of methyl methacrylate.

The utility model provides a kind of gold salt recovery pollution prevention and control device, comprising: rack, lifting frame, gas injection module, PCB workpiece and gold sink tank;The lifting frame is located in the inside upper side of the rack, the PCB workpiece is located at the bottom of the lifting frame, the gold sink tank is located directly below the PCB workpiece;The gas injection module is fixedly arranged in the inside of rack by the mounting bracket of its two sides, the gas injection module is located between the lifting frame and PCB workpiece, and is located directly above the PCB workpiece;Further comprising a blower, the blower is located in the outside of the rack, the blower is connected with the gas injection module by air supply hose;The utility model solves the problem of waste and pollution caused by gold water spatter to the outside, and the problem of gold salt concentration control disorder caused by the water of spray.

This invention discloses a gold nanoparticle, its preparation method, and its application, relating to the field of biomaterials technology. The gold nanoparticle is prepared by a method comprising the following steps: preparing a first mixed solution containing a gold salt, a ligand, and a stabilizer; performing a first reaction to obtain a reaction solution; preparing a second mixed solution containing a reducing agent and the reaction solution; and performing a second reaction to obtain the gold nanoparticle. The ligand has the structure shown in the following general formula: R1 is selected from Cl, Br, C1-C4 alkane groups or hydroxyl groups; R2 is selected from Cl, Br, C1-C4 alkane groups or hydroxyl groups. The prepared gold nanoparticle exhibits good biocompatibility and antibacterial properties, demonstrating significant social, economic, and technological benefits, as well as high practical application value and promising prospects for wider application.

The invention belongs to the technical field of biology, and relates to a colorimetric probe for detecting myoglobin and a detection method. The colorimetric probe comprises a reagent A and a reagent B: a solution containing iodide ions; the preparation method of the reagent A comprises the following steps: adding a reducing agent into a solution containing a copper salt and a coordination stabilizer, stirring, adding a water-soluble gold salt or gold acid when the solution turns from red to green, and continuously stirring for 1-100 minutes to obtain a copper-gold nanoparticle solution; the thioacetamide is subjected to a hydrolysis reaction in an acid solution to generate hydrogen sulfide, then the copper-gold nanoparticle solution obtained in the step S1 is added for a reaction, and a hydrogen sulfide modified copper-gold nanoparticle solution is obtained. Through a coupling mechanism of acidic H2S in-situ release-Au-S bond binding-I-etching, nanomole-level, high-selectivity and label-free colorimetric detection of myoglobin is realized, and the method has sensitivity, reliability, economical efficiency and field applicability, and can be widely applied to rapid screening.

This invention relates to the preparation of albumin-based gold clusters and their application in the treatment of inflammatory bowel disease (IBD), belonging to the pharmaceutical field. The method uses thiol-containing albumin as a template, mixes it with a trivalent gold salt compound under alkaline conditions, and irradiates it in a microwave reactor at 40–70°C for 1–5 cycles, each cycle lasting 1–10 minutes. This allows for the rapid synthesis of hydrated gold clusters with a particle size less than 20 nm and excellent fluorescence properties without the need for an external reducing agent. This method offers advantages such as rapid reaction speed, high yield, and good batch stability, overcoming the problems of long reaction time, low efficiency, and non-uniform products associated with traditional hydrothermal methods. The obtained albumin-gold clusters exhibit good biocompatibility and targeting properties, effectively accumulating at sites of intestinal inflammation after oral or injectable administration, achieving targeted therapy for IBD and providing a novel drug solution for the clinical treatment of IBD.

The present invention discloses a cyanide-free Au-Sn electroplating solution and its application, belonging to the field of electroplating technology. The electroplating solution is composed of a gold source, a tin source, a gold complexing agent, a tin complexing agent, an additive, and a pH buffer. The gold source is a gold salt of mercapto sulfonic acid, and the tin complexing agent is mercaptoacetic acid and its salts. The pH of the cyanide-free Au-Sn electroplating solution is 3-11. The electroplating solution provided by the present invention does not contain highly toxic substances, has high storage stability and electroplating stability, and remains clear and transparent even after high and low temperature changes, light exposure, long-term storage, or long-term electroplating. A Au-Sn alloy plating with uniform and stable composition and high reproducibility can be obtained during long-term storage or long-term electroplating, thus effectively ensuring the performance of the Au-Sn alloy plating obtained by electroplating. The electroplating solution has excellent performance and is conducive to application in the packaging technology of microelectronic or optoelectronic devices.

The invention provides a gold salt, a purification method of the gold salt, a cyanide-free electroplating solution and a preparation method and a use method of the cyanide-free electroplating solution. The cyanide-free electroplating solution mainly comprises the gold salt purified through the purification method in the embodiment of the invention and conductive salt. According to the purification method in the embodiment of the invention, firstly, sodium gold mercaptosuccinate with the gold content of 35-49.51 w / % is dissolved in hot pure water at the temperature of 60-80 DEG C, and a sodium gold mercaptosuccinate solution is obtained; dropwise adding the gold sodium mercaptosuccinate solution into a water-insoluble weak-polarity organic solvent to obtain a mixed solution; stirring the mixed solution, and purifying the mixed solution after stirring to obtain purified gold salt; the gold content of the gold salt is 55.01-56.9 w / %, the total impurity content is less than 0.01%, and the single impurity content is less than 5PPM. The gold salt obtained through the purification method is high in gold content and low in impurity content, the electroplating liquid prepared by taking the gold salt as the cyanide-free electroplating raw material is high in stability and long in service life, and the obtained gold-plated layer is good in quality.

The application discloses a method for recovering gold from a leaching solution containing a gold thiothiosulfate salt, comprising the following steps: (1) mixing gold-containing raw materials with a leaching solution, and performing solid-liquid separation after uniform mixing to obtain a leaching solution containing a gold thiothiosulfate salt; (2) mixing polyionic liquid with the leaching solution containing the gold thiothiosulfate salt to obtain a mixed solution, and performing solid-liquid separation after sufficient mixing until the polyionic liquid adsorption is completed, so as to obtain polyionic liquid adsorbed with gold; and (3) immersing the polyionic liquid adsorbed with gold into an acidic thiourea solution, and obtaining soluble gold salt after desorption; the structural formula of the polyionic liquid is shown in the following formula (I)-(IV); and the method disclosed by the application uses a plurality of polyionic liquids with special structures as adsorbents, and realizes efficient separation and recovery of gold from a gold thiothiosulfate salt system. (I); (II); (III); (IV).

The invention discloses a near-infrared second-region luminous gold-copper nanoprobe and a preparation method and application thereof, and the preparation method comprises the following steps: dissolving gold salt and a phase transfer agent in an organic solvent, stirring and dissolving, and standing in an ice bath; adding a phosphine ligand, rapidly stirring, and adding a reducing agent; adding a selenium ligand, continuously stirring and reacting, separating an organic phase, spin-drying, alternately washing with a good solvent and a poor solvent, and performing centrifugal crystallization and purification to obtain a black crystal precursor I; dissolving a copper salt in an alcohol solvent, adding an organic phosphorus ligand, carrying out a reaction, carrying out centrifugal separation on a precipitate, washing the precipitate with a poor solvent, and drying the washed precipitate to obtain a precursor II; and mixing and dissolving the precursor I and the precursor II in an organic solvent, stirring, centrifuging, taking a supernatant, spin-drying the supernatant, alternately washing with a good solvent and a poor solvent, and performing centrifugal crystallization purification to obtain the black crystal. The NIR-II luminescent imaging-guided tumor precise phototherapy material has precise atomic structure, photo-thermal conversion, NIR-II luminescence and active oxygen generation performance, and can be used for NIR-II luminescent imaging-guided tumor precise phototherapy.

The present application relates to the field of electroplating technology and discloses a method for synthesizing potassium gold cyanide from gold-plated waste. The present application rationally utilizes gold-plated waste in the electroplating industry. By using a combined reducing agent to recover and purify the gold-containing solution obtained from the gold-plated waste, the gold mud reduction time can be shortened and the gold mud reduction efficiency can be improved. The purified gold mud is reacted with potassium cyanide and hydrogen peroxide in a one-step reaction to synthesize potassium gold cyanide. This method not only has a high yield and purity, but is also simpler and safer than conventional processes. It is conducive to the large-scale synthesis and recycling of gold salts from gold-plated waste and the mass production of gold-containing ore mining, providing an environmentally friendly, low-cost, and high-yield process route for the future production of potassium gold cyanide.

A method for producing a gold sulfite by generating fulminating gold as an intermediate substance, and an object thereof is to provide a highly safe method. 【Solution means】A production method including the steps of acid-dissolving a gold raw material to prepare a chloroauric acid solution, adding aqueous ammonia to the chloroauric acid solution to precipitate fulminating gold, washing the fulminating gold with pure water and an alkaline aqueous solution, and adding a metal sulfite to the washed fulminating gold to prepare a gold sulfite solution solves the problem.

The invention relates to a high-stability cyanide-free gold sulfite electroplating solution and an electroplating method, the cyanide-free gold sulfite electroplating solution comprises a main salt, a coordination agent, a conductive salt, a pH buffer agent, a main additive, an auxiliary additive and a solvent, the main salt is a gold sulfite salt, the main additive is a benzenesulfonamide derivative, and the pH value of the electroplating solution is 8.5-10. The cyanide-free gold sulfite electroplating solution with the benzenesulfonamide derivative as the main additive has the advantages that the stability is high, and a prepared plating layer is fine in crystal, uniform and bright, low in internal stress, good in binding force and wide in operation window.

A process for preparing a catalyst for the oxidative esterification of methacrolein to methyl methacrylate, the process comprising providing a support selected from the group consisting of oxides of silicon, carbides of silicon, metal oxides, and metal carbides. Particles of at least one oxide of a metal are provided on the support. The support is brought into contact with a gold salt and heated at a temperature in the range of 50 DEG C to 600 DEG C for a time in the range of at least 0.1 hours to 48 hours to convert the gold salt into gold nanoparticles having an average diameter of less than 12 nm and a standard deviation of + / -4 nm. Wherein at least 75% by number of the gold nanoparticles are located within 20 nm of the particles of the oxide of the metal.

The invention discloses preparation and application of a gold cluster compound of a non-viral targeted in-vivo gene delivery vector, and relates to the field of application of non-viral gene delivery vectors. Au and a specific ligand protamine and Ang-2 peptide have a synergistic effect to form a cluster compound, and the molar ratio of Au to Pro to Ang-2 is 17: 25: (10-40), preferably 17: 25: 34. Mixing the gold salt solution with the ligand to form a mixed solution; under the conditions of certain temperature and pH, the mixed solution system is subjected to a reduction reaction, high-valence Au ions in the gold salt are reduced into Au atoms or monovalent Au ions, and Au forms a gold cluster compound through physical or chemical interaction; the sulfydryl-containing ligand is polypeptide or protein with better biocompatibility, and the cluster compound disclosed by the invention can be used for successfully delivering nucleic acid into cells and has good biocompatibility.

The invention relates to the technical field of chemical gold plating, in particular to high-stability chemical nanogold liquid and a preparation method thereof. The high-stability chemical nanogold liquid comprises the following preparation raw materials by mass concentration: 2-4 g / L of gold salt, 22-35 g / L of a reducing agent, 6-8 g / L of a complexing agent, 12-16 g / L of a pH regulator, 20-50 mg / L of a stabilizer, 50-80 mg / L of an accelerator, 0.8-1.2 g / L of a composite homogenizing agent and 0.008-0.012 mg / L of a water-soluble rhodium compound, and the reducing agent is composed of formaldehyde with the mass concentration of 37% and oxalic acid in a mass ratio of 2: 3-4. Through precise compatibility of the components and function synergy, the balance of high stability, high deposition rate, excellent coating quality and long service life of the chemical nanogold liquid is achieved, and the chemical nanogold liquid is particularly suitable for the fields of microelectronics, high-frequency connectors and the like with strict requirements for coating uniformity and has remarkable industrial application value.

The application relates to the technical field of chemical plating, and particularly discloses a cyanide-free electroplating gold plating solution applied to a wafer and a preparation method thereof. The cyanide-free electroplating gold plating solution comprises a gold salt, a main complexing agent, an auxiliary complexing agent, a crystal grain adjusting agent, an organic phosphonic acid additive, a buffer and deionized water. The crystal grain adjusting agent can adjust the grain size and structure of the plating layer, so that the plating layer is more compact and uniform. The organic phosphonic acid additive can replace the position of a coordination agent which is prone to cause inclusions, effectively controls the interface adsorption of a cathode, is favorable to improving the inclusions in the plating layer, and improves the plating layer quality.

The application discloses a method for recovering gold sulfite from cyanide-free gold plating waste liquid, and the stable gold sulfite solution is prepared through the steps of concentrating, filtering, anti-solvent precipitation and gold sulfite dissolving of the cyanide-free gold plating waste liquid. The cyanide-free gold plating waste liquid can be efficiently recovered by the method, and the gold sulfite for cyanide-free gold plating is directly obtained, a gold closed loop is formed, the gold turnover rate is accelerated, and the production cost is effectively reduced.