Wound healing compositions involving medicinal honey, mineral ions and methylglyoxal, and methods of use

a technology of mineral ions and methylglyoxal, which is applied in the field of wound healing compositions, can solve the problems of reducing the activity of wound protease, affecting the healing effect of wounds, and affecting the healing effect of wounds, and achieves the effect of modulating biochemical mechanisms and reducing the active infection and the active infection

a technology of mineral ions and methylglyoxal, which is applied in the field of wound healing compositions, can solve the problems of reducing the activity of wound protease, affecting the healing effect of wounds, and affecting the healing effect of wounds, and achieves the effect of modulating biochemical mechanisms and reducing the active infection and the active infection

US20170216369A1Inactive Publication Date: 2017-08-03SABACINSKI KENNETH A +1
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  • Wound healing compositions involving medicinal honey, mineral ions and methylglyoxal, and methods of use
  • Wound healing compositions involving medicinal honey, mineral ions and methylglyoxal, and methods of use
  • Wound healing compositions involving medicinal honey, mineral ions and methylglyoxal, and methods of use

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[0062]Objects and advantages of this invention are further illustrated by the following examples, but the particular materials and amounts thereof recited in these examples, as well as other conditions and details, should not be construed to unduly limit this invention.

[0063]Example 1 demonstrates composition 1, embodiments 1 and 2.

[0064]Monofloral buckwheat honey fortified with methylglyoxal at a concentration of 1000 mg / kg is prepared and impregnated into acetate non-woven medical grade dressing (approximately 4 g MGO-fortified buckwheat honey in each 4″×5″ dressing). The dressings are protected with polyethylene liners applied to both sides, and dressings of 4″×5″ are sealed individually in foil pouches constructed of white polyester film fused to aluminum foil that constitutes an excellent barrier. The dressings are then sterilized with gamma radiation and verified as sterile before use.

[0065]Panels 1A, 1B, 1C, and 1D, show treatment using dressings impregnated with composition ...

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Abstract

The invention provides compositions based on either medicinal honey containing broad spectrum antibacterial activities of peroxide, polyphenols and methylglyoxal, or an effective amount of an active anti-inflammatory ingredient of mineral solids fortified with methylglyoxal antibacterial activity, or a mixture of both for the treatment of wounds; and methods of treating a wound, comprising contacting a wound with any one of the above compositions or a wound dressing containing any one of the above compositions.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a continuation application of and claims priority from U.S. Nonprovisional patent application Ser. No. 15 / 010,896 filed on Jan. 29, 2016, which claims the benefit of U.S. Provisional Patent Application Ser. No. 62 / 109,369, filed Jan. 29, 2015. The foregoing applications are incorporated in their entirety herein by reference.FIELD OF THE INVENTION[0002]The invention broadly relates to wound healing compositions, more specifically to wound healing compositions including various combinations of medicinal honey, methylglyoxal, pharmaceutically acceptable carriers, inorganic minerals with methylglyoxal, salts, and medicinal buckwheat honey.BACKGROUND OF THE INVENTION[0003]Undesirable and dangerous side effects and adverse drug interactions are well known for the predominantly synthetic organic pharmaceuticals that have been widely administered over the past several decades. These adverse effects have led many research group...

Claims

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Application Information

Patent Timeline
03 Aug 2017
Publication
US20170216369A1
IPC
A61K35/644; A61K33/06; A61L15/20; A61K33/04; A61K33/00; A61L15/40; A61K31/11; A61K33/30
CPC
A61K35/644; A61K31/11; A61K33/06; A61K33/30; A61K33/04; A61L2300/404; A61L15/40; A61L15/20
Inventors
SABACINSKI, KENNETH A.; WARDELL, MARK R.