Compound for hormonous dermatitis, preparation, preparation method and application

A composition and dermatitis technology, applied in the field of biomedicine, can solve the problems of atrophy and thinning of the papillary dermis, decreased immune function, long treatment time, etc., and can inhibit bacterial infection, promote the formation of interstitial cells, and have a wide antibacterial spectrum. Effect

Inactive Publication Date: 2016-11-09
简婷婷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 2. The epidermis and dermis become thinner, and long-term use of hormones leads to atrophy and thinning of the stratum corneum and papillary dermis
[0007] 3. For facial microbial infection, hormones can inhibit the function of macrophages, affect the function of Langerhans cells, dissolve lymphocytes, and reduce the local immune function of the skin surface
[0009] Clinically, anti-inflammation, immune regulation, repair of skin barrier function, and inhibition of microbial growth on the skin surface are mainly used as treatment principles for steroid dermatitis.

Method used

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  • Compound for hormonous dermatitis, preparation, preparation method and application
  • Compound for hormonous dermatitis, preparation, preparation method and application
  • Compound for hormonous dermatitis, preparation, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Embodiment 1 provides a kind of skin repairing liquid suitable for steroid dermatitis, and its composition is as follows:

[0077] In parts by weight,

[0078] Phase A is: 85 parts of rose hydrosol, 0.05 parts of polylysine, 0.50 parts of jojoba wax, 2.00 parts of 1,2-glutaraldehyde, 1.50 parts of hydroxypropyl-β-cyclodextrin, EDTA-2Na0.08 2.00 parts of water-soluble vitamin E, 4072.50 parts of poloxamer, 1.00 parts of glycerin, 3.00 parts of 1,3-butanediol;

[0079] Phase B: 0.01 parts of grape seed extract, 0.50 parts of aloe vera gel, 0.30 parts of licorice extract, 0.50 parts of curcumin, 0.50 parts of apigenin, 1.00 parts of oat-β-glucan, 0.10 parts of amino dextran, water-soluble Azone 1.00 parts;

[0080] Phase C: 0.20 parts of allantoin, 0.50 parts of small molecule collagen, 1.50 parts of chitosan;

[0081] Phase D: 0.0003 parts of composite growth factor (that is, the concentration of composite growth factor in the final solution for hormone dermatitis repa...

Embodiment 2

[0089] Embodiment two provides a kind of skin repairing liquid suitable for steroid dermatitis, and its composition is as follows:

[0090] In parts by weight, phase A is: 50 parts of rose hydrosol, 0.01 part of polylysine, 1.00 parts of jojoba wax, 5.00 parts of 1,2-glutaraldehyde, 5.00 parts of hydroxypropyl-β-cyclodextrin, 0.01 part of EDTA-2Na, 2.00 part of water-soluble vitamin E, 0.5 part of polyvinylpyrrolidone, 1.00 part of glycerin;

[0091] Phase B: 0.1 parts of grape seed extract, 1.0 parts of aloe vera gel, 1.0 parts of licorice extract, 0.10 parts of curcumin, 0.10 parts of apigenin, 2.00 parts of oat-β-glucan, 1.00 parts of aminodextran, water-soluble Azone 0.10 parts;

[0092] Phase C: 0.20 parts of allantoin, 0.50 parts of small molecule collagen, 5.00 parts of tea polyphenols;

[0093] Phase D: 0.001 part of composite growth factor (that is, the concentration of composite growth factor in the final solution for hormone dermatitis repair is 10 micrograms per ...

Embodiment 3

[0101] Embodiment 3 provides a kind of skin repairing liquid suitable for steroid dermatitis, and its composition is as follows:

[0102] In parts by weight, phase A is: 85 parts of rose hydrosol, 0.10 parts of polylysine, 0.10 parts of jojoba wax, 1.00 parts of 1,2-glutaraldehyde, 0.50 parts of hydroxypropyl-β-cyclodextrin, 0.10 parts of EDTA-2Na, 2.00 parts of water-soluble vitamin E, 5.00 parts of polyethylene glycol, 5.00 parts of glycerin, 3.00 parts of 1,3-butanediol;

[0103] Phase B: 0.001 parts of grape seed extract, 0.10 parts of aloe vera gel, 0.10 parts of licorice extract, 1.00 parts of curcumin, 1.00 parts of apigenin, 0.50 parts of oat-β-glucan, 0.01 parts of amino dextran, water-soluble Azone 5.00 parts;

[0104] Phase C: 0.20 parts of allantoin, 0.50 parts of small molecule collagen, 0.50 parts of allicin;

[0105] Phase D: 0.0001 part of composite growth factor (that is, the concentration of composite growth factor in the final solution for repairing hormon...

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PUM

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Abstract

The invention relates to the field of biological medicine and specifically relates to a compound for hormonous dermatitis, a preparation, a preparation method and an application thereof. The compound comprises the following components: rose hydrosol, grape seed extract, aloe vera gel, liquorice extracting solution, curcumin, apigenin, oat-beta-glucan, amidogen glucan, water-soluble azone, polylysine, water soluble vitamin E, buxus chinensis, 1,2-glutaraldehyde, compound growth factor, hydroxypropyl-beta-cyclodextrin, EDTA-2Na, collagen, humectants, auxiliary material and natural preservatives. The components in the compound have mild action to skin and are free from irritation; the components are collocated with each other, can prevent inflammation and anaphylaxis caused by hormonous dermatitis on the basis of supplying moisture preservation and can restrain bacteria to infect the damaged skin. The added compound growth factor can promote metabolism and repairing of cells of corium layer, epidermis and especially cuticle and can promote the forming of intercellular substance, so as to repair the damaged skin and achieve the effects of protection and curing.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a composition, preparation, preparation method and application for steroid dermatitis. Background technique [0002] Hormone-dependent dermatitis is dermatitis caused by long-term and repeated improper use of external corticosteroids. The primary skin lesions disappear after topical glucocorticoids are used, but inflammatory lesions reappear after discontinuation. Repeated use of glucocorticoids is required to control symptoms and gradually An aggravated form of dermatitis. [0003] The detailed mechanism of the pathogenesis of steroid dermatitis is still unclear, but there are the following theories: [0004] The skin barrier function is damaged. There are many reasons for the damage of long-term topical hormone preparations to the skin barrier function, including: [0005] 1. Inhibit the proliferation of skin keratinocytes (KC), affect the differentiation of keratin and intermediat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/18A61K9/08A61K47/42A61K8/97A61K8/92A61K8/88A61K8/73A61K8/67A61K8/65A61K8/64A61K8/49A61K8/44A61K8/35A61K8/33A61Q19/00A61P17/00A61K31/12A61K31/198A61K31/352A61K31/716
CPCA61K36/87A61K8/33A61K8/35A61K8/44A61K8/4906A61K8/498A61K8/64A61K8/65A61K8/678A61K8/73A61K8/738A61K8/88A61K8/922A61K8/97A61K9/0014A61K9/08A61K31/12A61K31/198A61K31/352A61K31/716A61K36/484A61K36/738A61K36/886A61K36/896A61K38/18A61K38/1808A61K38/1825A61K47/42A61Q19/00A61K2300/00
Inventor 简婷婷
Owner 简婷婷
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