The invention relates to a production method for preparing a rumen bypass series product, and belongs to the technical field of feed and feed additives. The rumen bypass series product comprises aminoacid, choline chloride, glucose, urea or ammonium chloride. The production method comprises the following steps of sieving the raw materials, adding auxiliary materials, performing granulating, rounding and drying, heating and melting palm oil, adding a surfactant, spraying the surfactant into the dried materials in a fluidized bed, performing coating, and after coating, performing sieving to obtain the rumen bypass series product. Compared with the prior art, the method has the advantages that the production cost is relatively low, and the prepared rumen bypass series product is regular in shape, relatively narrow in particle size distribution, easy to add and premix and relatively high in product percent of pass.