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91 results about "Saccharolipid" patented technology

Saccharolipids describe compounds in which fatty acids are linked directly to a sugar backbone, forming structures that are compatible with membrane bilayers. In the saccharolipids, a monosaccharide substitutes for the glycerol backbone present in glycerolipids and glycerophospholipids. The most familiar saccharolipids are the acylated glucosamine precursors of the lipid A component of the lipopolysaccharides in Gram-negative bacteria. Typical lipid A molecules are disaccharides of glucosamine, which are derivatized with as many as seven fatty-acyl chains. The minimal lipopolysaccharide required for growth in E. coli is Kdo2-Lipid A, a hexa-acylated disaccharide of glucosamine that is glycosylated with two 3-deoxy-D-manno-octulosonic acid (Kdo) residues.

Intra-intestinal nutrient emulsion for tumor patients

The invention belongs to the medicine field, and specifically relates to an intra-intestinal nutrient emulsion for tumor patients. The emulsion is characterized by comprises the following effective components: protein, fat, carbohydrate, total dietary fiber, green tea theine, taurine, L-carnitine, composite vitamins and mineral substances, and water. The protein is provided in an amino acid powder form, the formula of the amino acid powder is adjusted on the basis of 20 kinds of protein amino acids, wherein methionine is replaced by homocysteine, glutamine and glutamic acid are not added, the tryptophan content is low, and the content of branched chain amino acid reaches 35% or more; fat is provided in a saturated aliphatic acid or unsaturated fatty acid form, wherein in the unsaturated aliphatic acid the value of omega-6 / omega-3 is equal to 2-6 / 1; and the carbohydrate is provided in a form of glycerin, glucose, fructo-oligosaccharide or lentinan. Besides one prominent characteristic of the emulsion is that the emulsion is a high-fat and low-sugar type, and the ratio of sugar to fat is 1:1. The emulsion formula is adjusted according to the nutrient and metabolism requirements of tumor patients so as to develop an individualized intra-intestinal nutrient preparation for tumor patients, the preparation can provide balanced nutrients for tumor patients, effectively cures the malnutrition symptom, improves the life quality of patients, and can also be used to assist the tumor treatment.
Owner:湖北一半天制药有限公司

Application of galactooligosaccharides and derivatives of galactooligosaccharides as SGLT inhibitor

The invention belongs to the field of marine medicine, and particularly relates to an application of oligosaccharides containing D-galactose and L-galactose and derivatives of the oligosaccharides asa sodium-glucose cotransporter (SGLT) inhibitor. The galactooligosaccharides and derivatives are prepared by the following steps: by using red algae polysaccharide containing the D-/L-galactose as a raw material, performing degradation by using a physical method, a chemical method, a bioenzyme method or any combination of the above methods to prepare the galactooligosaccharides and the derivativesof the galactooligosaccharides with different degrees of polymerization, wherein the molecular skeleton contains the D-galactose and the L-galactose and derivatives thereof. The raw material of the product provided by the invention is from the red algae polysaccharide, and has the advantages of rich resources, a simple preparation process, high safety, clear targets and easy industrialization, the oligosaccharides and the derivatives are used as the SGLT1 and 2 inhibitor, and has broad application prospects in the development of medicines for treating diseases such as diabetes mellitus, obesity, diabetic nephropathy and glucose and lipid metabolism disorder and functional foods for improving non-alcoholic fatty liver diseases.
Owner:OCEAN UNIV OF CHINA

Method for producing sophorose ester through fermenting waste molasses and waste glycerin

InactiveCN102329833ASolve the problem of difficult storage and large emission pollutionReduce manufacturing costFungiMicroorganism based processesBiotechnologySporeling
The invention relates to a method for producing sophorose ester through fermenting waste molasses and waste glycerin, which comprises the following implementation steps that: (1) spore suspension preparation: torulopsis utilis TJZKBA 10326 is inoculated on the inclined surface of a culture medium and is cultured for 2 to 4 days at the constant temperature being 30 DEG C, and normal saline with the mass concentration being 0.75 percent is added for washing mycelia, and the bacterial suspension is obtained; (2) the bacterial suspension is used for being inoculated into the sterilized liquid seed culture medium, the spore suspension is inoculated into the cooled liquid seed culture medium according to the inoculation quantity with the volume percentage being 2 to 5, and liquid seeds are obtained; (3) the liquid seed culture medium is used for being inoculated into a sterilized 5L fermentation tank, then, the liquid culture medium is inoculated into the cooled fermentation tank culture medium according to the inoculation quantity with the volume percentage being 2 to 5, the fermentation temperature is 30 to 34 DEG C, the dissolved oxygen is controlled to be 30 to 40 percent, and the fermentation time is 48 to 72h; and (4) after the fermentation is completed, the mixed organic solvent of organic solvent ethyl acetate / isopropanol with the same volume as the fermentation liquid is used for extracting the sophorose ester. The method has the advantages that the process is simple, the cost is low, and the effect is obvious.
Owner:天津实发中科百奥工业生物技术有限公司

Three-high reducing assisting composition and preparation method thereof

The invention relates to the field of healthcare foods. A three-high reducing assisting composition mainly comprises sea cucumber polypeptide, corn oligopeptide, extract of semen cassia, hawthorn extract, ginseng extract, dioscorease rhizome extract, extracts from pueraria, dendrobium extract, indian buead extract, prunus persica kernel extract, L-arabinose, xylooligosaccharide, dietary fiber, arabian jasmine flower, xylitol and nutritive yeast powder. According to the three-high reducing assisting composition, traditional Chinese medicine and high technology are combined; comprehensive conditioning and accurate targeted treatment are combined; the function test result shows that three high can be comprehensively conditioned by assisting, and the effects of integrally regulating sugar andfat and conditioning the three highs together can be achieved; and meanwhile, the intestinal functions can be improved, the body immunity can be improved, and as a result, the effect of treating bothsymptoms and root causes can be achieved; the formula is subjected to scientific mixing of oligopeptide and medical food materials, so that the effects of efficient utilizing, fast acting and assisting of three highs (blood sugar, blood pressure and blood fat) reducing are obviously achieved; in addition, hormone and drug independence are avoided, so that the safety of eating is ensured.
Owner:DALIAN SHENLAN PEPTIDE TECH R & D CO LTD

Functional edible oil as well as preparation method and application thereof

PendingCN112772731AImprove glucose and lipid metabolism disordersGood for healthEdible oils/fatsNutritionCarbon chain
The invention relates to functional edible oil as well as a preparation method and application thereof. The functional edible oil is formed by performing ternary ester exchange on medium- carbon-chain glyceride, linoleic acid grease and linolenic acid grease. On the basis of the mass of fatty acid, the mass ratio of medium-carbon-chain fatty acid in the medium-carbon-chain glyceride to long-carbon-chain fatty acid in the linoleic acid grease and the linolenic acid grease is 2.3-4.0, and the mass ratio of linoleic acid to linolenic acid in the long-carbon-chain fatty acid is 0.5-1.0. The addition amount of the functional edible oil in foods is greater than or equal to 18.00%. The functional edible oil can significantly improve in-vivo glucose and lipid metabolism disorder, balance and supplement in-vivo necessary and functional fatty acids, and rapidly supplement energy, has a freezing point lower than 7.5 DEG C, can meet consumers, particularly, dietary and nutritional requirements of patients with metabolic syndromes such as overweight, obesity, fatty liver, hyperlipidemia, hyperglycemia, hypertension, hyperblood viscosity, hyperuricemia and hyperinsulinemia and athletes can be met, and the functional edible oil can be widely applied to foods and special medical application industries.
Owner:NANCHANG UNIV

Biological polysaccharide gel for oil displacement as well as preparation method and application thereof

The invention belongs to the technical field of tertiary oil recovery and particularly relates to biological polysaccharide gel for oil displacement as well as a preparation method and application thereof. The biological polysaccharide gel comprises the following components in percentage by weight: 2 to 5 percent of biological polysaccharide, 0.1 to 0.5 percent of biological polysaccharide dispersant, 10 to 20 percent of biological polysaccharide gelatinizing agent, 0.5 to 2 percent of biological polysaccharide regulator and the balance of water, wherein the biological polysaccharide is one ofxanthan gum, Curdlan, Welan gum and sclemglucan; the biological polysaccharide dispersant is one of sophorolipid, rhamnolipid, lipopeptid and lipoprotein; and the biological polysaccharide regulatoris one of ferric sulfate, ammonium carbonate, sodium acetate and sodium hydrogen carbonate. The biological polysaccharide gel has high anti-shearing property, temperature resistance and salt resistance and has good application prospect particularly in an oil well of a high-temperature and high-salt oil reservoir; and in field application, the water content is reduced by over 10 percent, the validity period exceeds 60 days and the average daily-increased oil quantity is more than 5 t.
Owner:CHINA PETROLEUM & CHEM CORP +1

Sophorolipid compound for improving soil and spraying device

The invention discloses a sophorolipid compound for improving soil and a spraying device, and belongs to the field of soil remediation. The invention relates to a sophorolipid compound for improving soil. The sophorolipid compound is prepared from the following components: sophorolipid, NaCl, ethylenediamine tetraacetic acid, diethyl aminoethyl hexanoate, konjac glucomannan and water. The spraying device for improving the soil comprises a storage layer, a rotating layer and a base which are sequentially connected from top to bottom, a plurality of helical teeth are arranged at the joint of the storage layer and the rotating layer, outflow channels are arranged above the adjacent helical teeth, and the outflow channels are communicated with the storage layer. According to the technical scheme, due to the special sprayed substance, the sprayed substance is a sophorolipid compound with certain viscosity. Therefore, in the technical scheme, the sophorolipid compound flowing from the storage layer to the outflow channel is cut through the helical teeth, so that the agglomerated viscous compound is prevented from blocking the channel, the volume of the compound is reduced, the single-flow sophorolipid compound can be sprayed out conveniently, and the spraying speed and distance of the sophorolipid compound can be kept conveniently.
Owner:HEFEI UNIV OF TECH

Special grease base oil for functional food as well as preparation method and application of special grease base oil

PendingCN112772924AWide melting rangeImprove glucose and lipid metabolism disordersEdible oils/fats with fatty acid estersFood ingredient functionsBiotechnologyNutrition
The invention discloses special grease base oil for a functional food as well as a preparation method and application of the special grease base oil. The special grease base oil is formed by performing ternary ester exchange on medium-carbon-chain glyceride, high-melting-point fat and linolenic acid grease, and performing ternary ester exchange on the medium-carbon-chain glyceride, the high-melting-point fat and the linolenic acid grease under the conditions of temperature and stirring intensity by taking lipase as a catalyst, so as to obtain the special grease base oil for the functional food in one step. The special grease base oil for for the functional food is wide in melting range, can remarkably improve in-vivo glucose and lipid metabolism disorder, balance and supplement in-vivo necessary and functional fatty acids and quickly supplement energy, can meet the requirements of consumers, particularly, dietary and nutritional requirements of patients with metabolic syndromes such as overweight, obesity, fatty liver, hyperlipidemia, hyperglycemia, hypertension, hyperblood viscosity, hyperuricemia and hyperinsulinemia and athletes can be met, and the special grease base oil can be widely applied to grease powder, margarine and sports nutritional foods.
Owner:NANCHANG UNIV

Microbial pesticide granule containing trehalose lipid as well as preparation method and application of microbial pesticide granule

PendingCN113243363AGood dispersionPlay the role of film protectionBiocidePlant growth regulatorsMicroorganismActive agent
The invention relates to a microbial pesticide granule containing trehalose lipid. The microbial pesticide granule comprises the following components in parts by weight: a phase-B component: 85-95 parts by weight of a granule carrier; a phase B component: 0.1-10 parts by weight of mother powder of microbial pesticide active ingredients; and a phase-C component: 0.1-3 parts by weight of functional slurry, and the functional slurry comprises the following components in parts by weight: 1-10 parts by weight of a binder, 1-20 parts by weight of an inducer, 1-20 parts by weight of a trehalose lipid surfactant, 0.1-5 parts by weight of warning coloration and the balance of water, totaling 100 parts by weight. According to the microbial pesticide granule containing trehalose lipid, trehalose lipid is used as an auxiliary agent and has excellent surface activity and interface activity, and trehalose lipid is a biological source surfactant, so that the biological activity of thalli in microbial powder is guaranteed, and effective components of microorganisms can be quickly and uniformly distributed on the surface of a particle carrier, which is beneficial to rapid colonization of thalli of the microbial granules in soil, promotion of plant growth, improvement of crop growth traits and improvement of quality, meanwhile, the trehalose lipid has good corrosion resistance, radiation resistance, drying and dehydration resistance protection and the like, great convenience is brought to storage, transportation and use of the microbial pesticide granules, and the storage period is guaranteed.
Owner:TIANJIN HIGHPOINT PLANT PROTECTION

Application of pharmaceutical adjuvant, sophorolipid, in field of medicine

The invention discloses an application of a pharmaceutical adjuvant, sophorolipid, in the field of medicine. Sophorolipid can be used as a pharmaceutical adjuvant in pharmaceutical production, and isnatural and nonhazardous, good in biocompatibility, strong in surface activity, dispersing capacity and emulsifying capacity, and capable of remarkably improving the stability of a main drug and the drug loading capacity and directly prolonging the drug storage time. Sophorolipid contains any one of lactone type sophorolipid and acid type sophorolipid or a mixture of the two in any ratio. The pharmaceutical adjuvant, sophorolipid, can be used for preparation of micro emulsion, submicron emulsion, lipidosome, microcapsules, magnetic medicine preparations or other preparations or other intramuscular injection or intravenous injection preparations with a surfactant. By adding the pharmaceutical adjuvant into preparation systems of different dosage forms with the proportion of 0.05%-3%, dosageforms meeting requirements can be prepared; the drug loading capacity and the preparation storage time are both obviously superior to those of a conventional surfactant, Tween 80, the adverse reaction occurring rate is lower than that of Tween 80, and therefore, the pharmaceutical adjuvant, sophorolipid, is an excellent natural microbial pharmaceutical adjuvant.
Owner:HEFEI UNIV OF TECH +1

Medicine for relieving glucose and lipid metabolism disorder and improving vascular function and preparing method for medicine

The invention belongs to the technical field of medicine and pharmacology, and discloses a medicine for relieving glucose and lipid metabolism disorder and improving the vascular function and a preparing method for the medicine. The medicine for relieving glucose and lipid metabolism disorder and improving the vascular function is salvianolic acid B. The molecular formula of salvianolic acid B is C36H30O16. The preparing method for the medicine for relieving glucose and lipid metabolism disorder and improving the vascular function comprises the following steps that radix salviae miltiorrhizae medicinal materials are smashed into fine powder and are sieved through a 20-60-mesh sieve; an ethanol solution is added into the fine powder, the fine powder is soaked under the temperature less than 5 DEG C, ultrasonic extracting is conducted, and the extraction process temperature is lower than 25 DEG C; centrifuging is conducted on extracted liquid, filtering is conducted, ethanol is recovered after pressure reducing till the extracted liquid has no alcohol smell, and the extracted liquid is concentrated and filtered; and the extracted liquid is clarified, enrichment is conducted through macroporous resin first, then chromatographic column chromatography purifying is conducted, freezing and drying are conducted, and a salvianolic acid B extract substance is obtained. The medicine for relieving glucose and lipid metabolism disorder and improving the vascular function has the good protective effect on myocardial infarction and also can obviously relieving injuring of myocardial ischemia / reperfusion; thrombus is prevented from forming by anti-platelet aggregation; microcirculation is improved; and anti-oxidation injury is avoided.
Owner:成都医学院第一附属医院

Bifidobacterium longum 070103 with effects of remarkably reducing blood sugar and blood fat by targeting glucokinase and application of bifidobacterium longum 070103

The invention discloses bifidobacterium longum 070103 capable of remarkably reducing blood sugar and blood fat by targeting glucokinase and application of the bifidobacterium longum 070103. The preservation number of the Bifidobacterium longum 070103 is GDMCC (China General Microbiological Culture Collection Center) NO: 62526, and the preservation number of the Bifidobacterium longum 070103 is CGMCC NO: 62526. The bifidobacterium longum 070103 is separated from intestinal flora of healthy people, when the bifidobacterium longum 070103 is used for fermenting milk, the bifidobacterium longum 070103 has an activation effect on human liver glucokinase in vitro, in addition, the strain is derived from excrement of the healthy people and has no toxic or side effect on the human body, and meanwhile, the whole genome sequencing analysis finds that the strain is free of toxic genes, so that the bifidobacterium longum 070103 can be used for fermenting milk. Compared with traditional medicines for treating glucose and lipid metabolism disorder metabolic diseases such as obesity and type 2 diabetes mellitus, the pharmaceutical composition has certain advantages. The strain can be used for preparing probiotic fermented milk and has a wide market prospect.
Owner:GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY +2

Biochar material for efficiently reducing soil arsenic pollution and preparation method thereof

The invention discloses a biochar material capable of efficiently reducing soil arsenic pollution. A preparation method of the biochar material comprises the following steps: S1, airing tea residues,crushing the tea residues, heating the tea residues to 500-600 DEG C, keeping the temperature for 2-3 hours, stopping heating, and conducting grinding and sieving for later use; S2, adding biochar obtained in the step S1 into an aqueous sodium alginate solution, conducting stirring for 3-4 hours, then slowly and dropwise adding the formed solution into an aqueous CaCl2 solution, continuing stirring for 6-8 hours in the process of dropwise adding, carrying out filtering, performing washing with water, and carrying out drying in vacuum for later use; and S3, adding a product obtained in the stepS2 into an aqueous cellobiose lipid solution, carrying out standing for 3-4 hours, performing ultrasonic treatment for 30-60 min, and carrying out filtering and vacuum drying to obtain the biochar material. The biochar material disclosed by the invention can maintain efficient and lasting adsorption and immobilization effects on effective arsenic in soil, and the component materials of the biochar material are natural and do not influence nutrients and trace elements in the soil, so the growth of planted crops is not influenced, and the content of arsenic in the planted crops can be effectively reduced.
Owner:景德镇市子轩知识产权服务有限公司
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