The invention belongs to the technical field of
medicine and
pharmacology, and discloses a
medicine for relieving glucose and
lipid metabolism disorder and improving the
vascular function and a preparing method for the
medicine. The medicine for relieving glucose and
lipid metabolism disorder and improving the
vascular function is
salvianolic acid B. The molecular formula of
salvianolic acid B is C36H30O16. The preparing method for the medicine for relieving glucose and
lipid metabolism disorder and improving the
vascular function comprises the following steps that radix salviae miltiorrhizae medicinal materials are smashed into
fine powder and are sieved through a 20-60-mesh
sieve; an
ethanol solution is added into the
fine powder, the
fine powder is soaked under the temperature less than 5 DEG C, ultrasonic extracting is conducted, and the extraction process temperature is lower than 25 DEG C; centrifuging is conducted on extracted liquid, filtering is conducted,
ethanol is recovered after pressure reducing till the extracted liquid has no
alcohol smell, and the extracted liquid is concentrated and filtered; and the extracted liquid is clarified, enrichment is conducted through
macroporous resin first, then
chromatographic column chromatography purifying is conducted, freezing and
drying are conducted, and a
salvianolic acid B extract substance is obtained. The medicine for relieving glucose and
lipid metabolism disorder and improving the vascular function has the good protective effect on
myocardial infarction and also can obviously relieving injuring of
myocardial ischemia / reperfusion;
thrombus is prevented from forming by anti-
platelet aggregation;
microcirculation is improved; and anti-oxidation injury is avoided.