Chewable soft capsules and method for preparing same

A technology of soft capsules and chewability, which is applied in the field of chewable soft capsules and its preparation, can solve the problems of poor temperature resistance, affecting the taste, and easy adhesion of soft capsules, and achieve reasonable proportioning, good temperature resistance, and chewing good sex effect

Active Publication Date: 2012-03-21
SIRIO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] But there is following defective in above-mentioned prior art: (1) in order to make capsule easy to chew, must possess suitable chewing degree
Increasing the amount of plasticizer such as U.S. Patent US6280767 or maintaining a high moisture content such as U.S. Patent Application US20050136104 can keep the capsule soft and easy to chew, but this will lead to easy adhesion between soft capsules and soft capsules The adhesion between the packaging container and the poor temperature resistance will affect the storage stability of the product, especially not suitable for high-temperature and high-humidity areas; (2) After ordinary soft capsules are broken, the rubber cannot be quickly dissolved or dispersed, and cannot It is easy to be swallowed, and the elastic body like chewing gum will remain in the oral cavity, which will affect the acceptance of the eater; (3) due to the smell of the rubber itself, and the content accounts for 60-90% of the weight of the whole capsule, some of the content The bad smell of raw materials will greatly affect the taste when people take it
Chinese patent application 200910088218.6 and Chinese patent ZL00806658.2 respectively improved the taste of the rubber and the contents, but the distribution of the taste of the rubber and the contents is very uneven when chewing

Method used

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  • Chewable soft capsules and method for preparing same
  • Chewable soft capsules and method for preparing same
  • Chewable soft capsules and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-2

[0063] In Table 5 below, formulas 1-2 adjust the amount of plasticizer so that the hardness of the soft capsule is moderate. The formula of its content is characterized by fish oil, which has a strong fishy smell. Some people will burp after taking the control 1 sample, and the hiccup process has a fishy smell. Add flavors to the content through formulas 1-2 to alleviate this phenomenon . According to judgment standard, and embodiment is evaluated, as table 6.

[0064] Table 5. Soft capsule formula (kg)

[0065] example

[0066] The preparation method of above-mentioned soft capsule, step is as follows:

[0067] (A) Glue preparation: Weigh purified water and glycerin and mix well, add cellulose and stir evenly, the temperature of the glue tank reaches 55°C, put in gelatin and stir well, the temperature rises to 85°C, after the gelatin is dissolved, add it and dissolve it in purified water in advance The final sucralose is stirred evenly, and the obtained mixed glu...

Embodiment 3-5

[0075] The temperature resistance of the thickener selected in the present invention is better than that of gelatin, and the addition of the thickener in the following examples in Table 7 can improve the temperature resistance of the soft capsule, and the anti-adhesion ability will also be improved thereupon. According to judgment standard, and embodiment is evaluated, as table 8.

[0076] Table 7. Soft capsule formula (kg)

[0077] example

[0078] The preparation method of above-mentioned soft capsule, step is as follows:

[0079] (A) Glue preparation: Weigh purified water and plasticizer, mix well, add thickener and stir evenly, the temperature of the glue tank reaches 55°C, put in gelatin and stir well, the temperature rises to 90°C, add gelatin after dissolving and use in advance The purified water dissolves the processed pigment and essence and stirs evenly to obtain a mixed glue. The mixed glue is kept at a vacuum degree of -0.09Mpa and a temperature of 90°C...

Embodiment 6-9

[0087] The following examples in Table 9 highlight the color and fragrance of the product, such as recipes 6-7, exemplifying different flavor essences, which can be selected or matched according to preferences, and natural source essences can also be used. Formulations 8-9 can be selected from the appearance and color matching to make the product more attractive. According to the judging criteria, and the embodiment is evaluated, especially the crowd trial food acceptance index item, as shown in Table 10.

[0088] Table 9. Soft capsule formula (kg)

[0089] example

[0090] The preparation method of above-mentioned soft capsule, step is as follows:

[0091] (A) Glue preparation: Weigh purified water, plasticizer, sweetener and mix evenly, add thickener and stir evenly, the temperature of the glue tank reaches 55°C, put in gelatin and stir well, the temperature rises to 95°C, after the gelatin is dissolved Then add the pigment dissolved in purified water in advance ...

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Abstract

The invention discloses chewable soft capsules, which comprise capsule shells and contents sealed in the capsule shells. The chewable soft capsules are characterized by comprising the following raw materials in part by weight: 25 to 65 parts of glutin, 1 to 25 percent of thickening agent, 18 to 65 parts of plasticizer, 4 to 16 parts of water and a mixture containing one or more of 0.005 to 20 parts of sweetening agent, 0.005 to 2 parts of essence, 0.0001 to 10 parts of pigment and 0.0001 to 5 parts of acid additive. The invention also discloses a method for preparing the novel chewable soft capsules. The chewable soft capsules have the advantages of reasonable blending ratio, proper hardness, good temperature resistance, no adhesion, no deformation, stable storage, quick dissolution of effectively components and high chewiness; and when the chewing soft capsules are chewed, tastes of the capsule shells and the contents easily and uniformly spread in the mouth so as to cover up bad taste of raw materials.

Description

technical field [0001] The invention relates to a health food and a preparation method thereof, in particular to a chewable soft capsule and a preparation method thereof. Background technique [0002] In view of its unique sealing characteristics, soft capsules can effectively ensure the stability of active ingredients in the contents, and soft capsules have been widely used due to their dose controllability and portability. In addition to being used in medicines, soft capsules are also widely used in many health-enhancing health foods. In recent years, there has been an increasing demand for chewable soft capsules that are easy to take even without water, for the purpose of improving ingestibility. Chewable soft capsules do not have a disintegration process, so the active ingredients are absorbed quickly, which is especially suitable for children, the elderly and those who have difficulty swallowing. U.S. Patent US6280767 discloses a chewable soft capsule, which keeps the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A23L1/29A23P1/04A23L33/00A23P10/30
Inventor 陈琼方素琼林桂萍张志勇李建英
Owner SIRIO PHARMA CO LTD
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