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161 results about "Anthraquinone Derivatives" patented technology

Anthraquinone derivative, as well as preparation method and application of anthraquinone derivative serving as antibacterial agent

InactiveCN102603525AHas selective inhibitory activityAntibacterial agentsOrganic active ingredientsEscherichia coliBacillus cereus
The invention provides an anthraquinone derivative, as well as a preparation method and application of the anthraquinone derivative serving as an antibacterial agent. The preparation method comprises the following steps: culturing a strain of Nigrospora sp. (HM565952) in a strain culture medium; fermenting the nigrospora sp. in a fermentation culture medium; filtering the fermentation broth, removing thallus, and extracting the fermentation broth with ethyl acetate; concentrating the extract, and performing chromatographic separation, and concentrating the eluent to obtain two types of yellow powder, namely 3,5,8-Trihydroxy-7-methoxy-2-methylanthracene-9,10-dione and austrocortirubin; and adding an acetic anhydride reagent in a solution dissolved with the compound, and reacting to obtain the anthraquinone derivative. The anthraquinone derivative obtained from the Nigrospora sp. (HM565952) has selective inhibitory activity to Bacillus subtilis, Bacillus cereus, Micrococcus tetragenus, Micrococcus lutea, Escherichia coli, Staphylococcus aureus, Staphylococcus albus, Vibrio parahaemolyticus and Vibrio anguillarum, and can be used for developing selective bacteriostatic agents; and the raw materials can be produced on a large scale, and not limited by resources. Therefore, the anthraquinone derivative has the advantage of wide application prospect.
Owner:OCEAN UNIV OF CHINA

Hydracid bisazo double-active-group reactive brilliant blue dyes, and preparation method and application thereof

The invention relates to hydracid bisazo double-active-group reactive brilliant blue dyes, and a preparation method and application thereof. The structural formula of the dyes is disclosed in the specification, wherein when R1=-SO3Na or H, R2=-H; and when R2=-COONa, R1=-H, and R3 is disclosed in the specification. The preparation method comprises the following steps: carrying out reaction on cyanuric chloride and 3,5-diamido-2,4,6-trimethylbenzenesulfoamino substituted anthraquinone derivatives to obtain a primary polycondensation solution; adding 2,4-diamidobenzenesulfonic acid (sodium 2,4-diamidobenzenesulfonate) or 3,5-diamidobenzoic acid (sodium 3,5-diamidobenzoate), and reacting to obtain a secondary polycondensation substance; carrying out diazotization on the para-position ester or meta-position ester to obtain diazonium salts; adding hydracid, and reacting to obtain an acidic coupling product; carrying out diazotization on the secondary polycondensation substance to obtain secondary polycondensation substance diazonium salts; and adding the secondary polycondensation substance diazonium salts into the acidic coupling product, and reacting to obtain the hydracid bisazo double-active-group reactive brilliant blue dyes. The dyes have the advantages of bright color, high fixation rate, favorable fastness, short dyeing equilibrium time and high substantivity, and can be used for dyeing and dye printing of cellulose fibers and protein fibers.
Owner:TAIZHOU QIANJIN CHEM CO LTD

Synthesis method, derivative and battery system of anthraquinone derivative containing carboxyl group

The invention provides a synthesis method, a derivative and a battery system of an anthraquinone derivative containing a carboxyl group. The synthesis method of the anthraquinone derivative containingthe carboxyl group includes the following steps that S1, dibasic acid containing a terminal carboxyl group and sulfoxide chloride are mixed, toluene is added as a reaction solvent, a catalyst is added, and heated to a set temperature reaction; S2, after the reaction is completed, the solvent and the sulfoxide chloride are removed, the toluene is added for distillation, and a reactant is obtained;S3, the reactant is mixed with amino-anthraquinone, the toluene is added as the reaction solvent, and heating is conducted to a reflux reaction; and S4, after the reaction is completed, the solvent is removed, solids are filtered and removed, the pH value of a filtrate is adjusted to a predetermined value, the solids are separated out, filtered, washed and dried, and the anthraquinone derivativecontaining the carboxyl group is obtained. According to the synthesis method of the anthraquinone derivative containing the carboxyl group, simpleness is achieved, operation is easy, the cost is low,and the synthesis method can be applied to the battery system to solve the problem of electrochemical energy storage.
Owner:CHINASALT JINTAN

Accessory ingredient used for bleaching slurry oxygen delignification and application thereof

The invention discloses an accessory ingredient used for bleaching slurry oxygen delignification, which aims to solve the problems that the traditional oxygen delignification technology adopts magnesium sulfate or sodium tripolyphosphate as fiber protection accessory ingredient to cause single chemical component and poor action effect, and can not perform good delignification action, and the improvement of the whiteness of the subsequent bleaching slurry is affected due to uneven reaction of oxygen and lignin. The accessory ingredient comprises the following components in percentage by weight: 5-15% of sodium dodecyl benzene sulfonate, 3-20% of sodium lignosulphonate, 5-25% of anthraquinone derivative, 25-65% of sodium sulfite and 1-15% of sodium tripolyphosphate. The accessory ingredient disclosed by the invention is compounded by various components, the delignification rate, the slurry yield and the slurry whiteness can be effectively improved, and the fiber is prevented from being degraded. Meanwhile, the use amount of bleaching agent in the subsequent bleaching process is effectively reduced, pollution on the environment by bleaching waste water is lowered, and the accessory ingredient has a higher economic value and a higher use value.
Owner:SICHUAN UNIVERSITY OF SCIENCE AND ENGINEERING

Synthesis and pharmaceuticals of novel bis-substituted anthraquinone derivatives

This invention relates to novel anthraquinone compounds useful in the treatment of allergic, inflammatory conditions, antioxidant, tumor condition, stem cell application, tissue engineering, applied in treating age-associate tissue degeneration, reverse organ failure in chronic high-turnover disease and therapeutic compositions containing such compounds. The compounds of the present invention are 1,4-, 1,5- and 1,8-difunctionalized anthraquinones or analogs thereof. According to the practice of the invention, there are provided bis-symmetrical substituted anthraquinone compounds according to formula I:
wherein R1, R2, R3 and R4 present a straight, aminoalkylamino side chains or branched chain alkyl group having 1 to 6 carbons which may be substituted with one or more groups of R5, or R1, R2, R3 and R4 present phenyl or benzyl which may be substituted with one or two groups of R6; wherein R5 is selected from the group consisting of halogen, —RNH2, —RNH2R, —ROH, —NO2, —OCH3, —OCH2CH3, and —OCH2CH2CH3; and wherein R6 is selected from the group consisting of a straight or branched chain alkyl group having 1 to 4 carbons, halogen, —RNH2, —RNH2R, —ROH, —NO2, —OCH3, —OCH2CH3, —OCH2CH2CH3, —CH2Br, —CH2Cl, —CH2OH, —C(CH3)3, —(CH2)20H, —(CH2)3OH, —(CH2)4OH, —CH2NH2, —(CH2)2NH2, —(CH2)3NH2, —(CH2)4NH2, —(CH2)5NH2, —CH2N(CH3)2, —(CH2)2N(CH3)2, —(CH2)2NH(CH2)2OH, —(CH2)3NH(CH2)2OH, —(CH2)2NHCH2OH, —(CH2)3NHCH2OH, —CH2CH(CH3)2, —CHCl2, —CH(CH3)Cl, —(CH2)2Cl, —(CH2)3Cl, —(CH2)3Br, —(CH2)4Br, and —(CH2)4Cl.
Chart 1. Activation of hTERT promoter-driven SEAP expression by c-Myc. About 1×107 hTERT-BJ1 cells were transfected with 13.5 μg each of plasmid pSEAP or pPhTERT-SEAP and of plasmid pMT2T or pMT2T-cMyc by electroporation. After 24 h, viable cells were harvested, and reinoculated at a density of 3×105/mL, and the SEAP activity after 24 h at 37 □. The transfection efficiency of each experiment was determined by cotransfection with 1.5 μg of plasmid pCMVβ. The values were determined from three experiments. P<0.05 is presented by an asterisk.
Owner:HUANG HSUSN
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